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VHRNVYVRRGQQLTPVTRAVAAWLWSGRTATLAGLSAAALHRTAWIDDWLPAELNRAGRDKARGIILHSD TLCDDETTMRDGMSLTTPARTAFDLGRRKGLTTAVIRLDALMHASDVKTADVELLADRHRGARGLVQLRR VLTLVDGGAESPYETKTRLLLAGSGLPRPQTQIEVRNEWGAVLARIDMGWEEWKVGVEFDGAQHWTDPAQ RTRDIDRFAELEARGWTIVRVSADMLRYRPYDILSRTRNALRASGCPLRSPSVDLLGTTQPISPNKSTFG GKGRPFGGKGRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1002 | - | - | 100% (293) | hypothetical protein MAV_1002 |
| M. avium 104 | MAV_3234 | - | 2e-82 | 58.91% (258) | hypothetical protein MAV_3234 |
| M. avium 104 | MAV_4706 | - | 2e-69 | 54.51% (255) | hypothetical protein MAV_4706 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3585c | - | 1e-71 | 54.30% (256) | hypothetical protein Mb3585c |
| M. gilvum PYR-GCK | Mflv_1289 | - | 1e-54 | 46.12% (258) | hypothetical protein Mflv_1289 |
| M. tuberculosis H37Rv | Rv3555c | - | 1e-70 | 53.91% (256) | hypothetical protein Rv3555c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4161 | - | 2e-73 | 54.33% (254) | hypothetical protein MAB_4161 |
| M. marinum M | MMAR_4658 | - | 2e-99 | 70.24% (252) | hypothetical protein MMAR_4658 |
| M. smegmatis MC2 155 | MSMEG_5314 | - | 2e-75 | 56.25% (256) | hypothetical protein MSMEG_5314 |
| M. thermoresistible (build 8) | TH_3487 | - | 1e-78 | 56.20% (258) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0276 | - | 2e-95 | 68.25% (252) | hypothetical protein MUL_0276 |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | 9e-85 | 58.27% (266) | hypothetical protein Mvan_5044 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3585c|M.bovis_AF2122/97 -------MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVEL
Rv3555c|M.tuberculosis_H37Rv -------MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVEL
MAB_4161|M.abscessus_ATCC_1997 -------MGDVPWPLIRSEALTNRVVTGYALRQ-FTALYPGIYAPTDAQI
TH_3487|M.thermoresistible__bu -------MAEG--PFLGSEARAAGLVTRRTLRSRHRLIYQNVYLPVGVQL
MMAR_4658|M.marinum_M -------MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIPRGKKL
MUL_0276|M.ulcerans_Agy99 -------MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIARGKKL
MAV_1002|M.avium_104 ------------------------------------MVHRNVYVRRGQQL
Mvan_5044|M.vanbaalenii_PYR-1 -----------MDPFLGTEALAAGSLTRYRLKTRFELVHRNVYALNREQL
MSMEG_5314|M.smegmatis_MC2_155 MGCDRPGMQTIDWPFRAVEALEAGALTFRELRRFHTAVYPGVWVPREAEL
Mflv_1289|M.gilvum_PYR-GCK -------MTAMDRVILGGEAVRAGVATRHELARDYTRLYRGVFVRNGIEI
:: .:: ::
Mb3585c|M.bovis_AF2122/97 TARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPP
Rv3555c|M.tuberculosis_H37Rv TARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPP
MAB_4161|M.abscessus_ATCC_1997 TPRKRAEAAWLWSRRKGTIAGISAAALHGTKWLPQQGPVVLIHTNRRAPR
TH_3487|M.thermoresistible__bu TAQTRAVAAWLWARRDATVAGLSAAALHGTKWIDPALPAELIRPSPGSPD
MMAR_4658|M.marinum_M TAVTRAIAAWLWSGRSATAVGLSAAALHRTGWIDDWLPAELNRRGRDKAR
MUL_0276|M.ulcerans_Agy99 TAVTRAIAAWLWSGRSATAVGLSPAPLHRTGWIDDWLPAELNRRGRDKAR
MAV_1002|M.avium_104 TPVTRAVAAWLWSGRTATLAGLSAAALHRTAWIDDWLPAELNRAGRDKAR
Mvan_5044|M.vanbaalenii_PYR-1 TPVQKARAAWLWSGRRGTLVGLSAAAVLGSRWIDARLPAELNQRSQHKTP
MSMEG_5314|M.smegmatis_MC2_155 SPVQRARAAWLWSGRAGVPAGLSASAMLGSKWIDQRDPAELIHTNRRPPR
Mflv_1289|M.gilvum_PYR-GCK TLRDRAIGAWLATGRKGVISGRTAAALHGAPLVDLTIPIELTGAKGRSQE
: :* .*** : * .. * :.:.: : : *
Mb3585c|M.bovis_AF2122/97 RIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALA
Rv3555c|M.tuberculosis_H37Rv RIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALA
MAB_4161|M.abscessus_ATCC_1997 GITLWSDSLPEGERMFVDGLPVTTPARTAFDIGRRTPVDL-AVQHLDALM
TH_3487|M.thermoresistible__bu GIVIHRDRLEPGEVCTLRGIPVTTPARTAYDIGRRQTLTR-AVVRLDALA
MMAR_4658|M.marinum_M GIISHSACLDEDEVCVRDGIALTTPARTAFDLGRRKGLTT-AVIRLDALT
MUL_0276|M.ulcerans_Agy99 DIISHSACLDEDEVCVRDGIALTTPARTAFDLGRRKGLTT-AVIRLDALT
MAV_1002|M.avium_104 GIILHSDTLCDDETTMRDGMSLTTPARTAFDLGRRKGLTT-AVIRLDALM
Mvan_5044|M.vanbaalenii_PYR-1 GIVLRADTLGPDEIVTARGMPVTSPARTAFDLGRRRGLTL-AVIRMDALM
MSMEG_5314|M.smegmatis_MC2_155 LLTVHSDTLSDGETQVIDGMVVTTPARTAFDLGRRLPFVD-GVQRIDALM
Mflv_1289|M.gilvum_PYR-GCK GLILRNESLAPDEVTRRSGLPVSTRVRTAFDLGRHLERPE-ALARLDALM
: * * *: ::: .***:*:**: .: ::***
Mb3585c|M.bovis_AF2122/97 NSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLI
Rv3555c|M.tuberculosis_H37Rv NSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLI
MAB_4161|M.abscessus_ATCC_1997 NATRLSRTDIETVATHHRGARGLHHLANVLGLVDGGAESPWETRTRLLVV
TH_3487|M.thermoresistible__bu NATGLTADAVTAVIDRRRGARGLVRLRRAVGLMDGGAASPPETRTRLLLL
MMAR_4658|M.marinum_M RATELKVADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLVI
MUL_0276|M.ulcerans_Agy99 RATELKVADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLII
MAV_1002|M.avium_104 HASDVKTADVELLADRHRGARGLVQLRRVLTLVDGGAESPYETKTRLLLA
Mvan_5044|M.vanbaalenii_PYR-1 RTTGATTSDIATLLTRHKGARGLVQLRRALELVDPASESPQESRTRLLLV
MSMEG_5314|M.smegmatis_MC2_155 NATHVKVEEVLALAEGYRGARGVRRLRLILEYVDGGAESPYESSTRIMLV
Mflv_1289|M.gilvum_PYR-GCK WNQRYAIDDVLALAERHPRARGVTQLRELLPLVDGGAASPRESALRLALI
: : ***: :* : :* .: ** *: *: :
Mb3585c|M.bovis_AF2122/97 DAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRA
Rv3555c|M.tuberculosis_H37Rv DAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRA
MAB_4161|M.abscessus_ATCC_1997 RAGFPAPQTQLVVRNRFGDFVARLDMGWPDHKVGIEFDGAQHWTSAQQRT
TH_3487|M.thermoresistible__bu AAGFPRPRTQVVVCDPFGYFIGRIDIGWPEYRVGVEYDGAWHWADAAAHA
MMAR_4658|M.marinum_M RSGLPAPQTEIKVLDDWGAVAARIGMGWPECKVGVEFDSAGQWNN-AARS
MUL_0276|M.ulcerans_Agy99 RSGLPAPQTEIKVLDDRGAVAARIGMGWPECKVGVEFDSAGQWNN-AARS
MAV_1002|M.avium_104 GSGLPRPQTQIEVRNEWGAVLARIDMGWEEWKVGVEFDGAQHWTDPAQRT
Mvan_5044|M.vanbaalenii_PYR-1 KAGLPPERSQIDVFDRDGYHVGRVDMGWETWKVGVEYEGEQHWTNPEQYA
MSMEG_5314|M.smegmatis_MC2_155 TNGFPEPETQIEVADASGTVFARLDMGWPEYRVAVEFDGAQHWTDSEQRS
Mflv_1289|M.gilvum_PYR-GCK DSGFPKPETQIPVFAG-TRPIAFLDMGWEEYGVAVEYDGDHHRKDRRQYV
*:* .::: * . :.:*: *.:*::. : .
Mb3585c|M.bovis_AF2122/97 RDIERSTALLDLGWTIIRVTSELLRYRRGTFVGRVDAAMRAAGWRP----
Rv3555c|M.tuberculosis_H37Rv RDIERSTALLDLGWTIIRVTSELLWYRRGTFVGRVDAAMRAAGWRP----
MAB_4161|M.abscessus_ATCC_1997 RDIDRATELVDEGWRIIRVSSDMVRHRSGTILARVAEAFVAARAA-----
TH_3487|M.thermoresistible__bu QTIDRVADLEEQGWIIIRISRDILRYRPGVFLARVRNALRAHGWPDHASV
MMAR_4658|M.marinum_M DAVDRSAELEARGWTIVRVNAQTLKNRPDIVVAQVRHALVR-----RT--
MUL_0276|M.ulcerans_Agy99 DAFDRSAELEARGWTIVRVNTQTLKNRPDIVVTQVRHALVR-----RT--
MAV_1002|M.avium_104 RDIDRFAELEARGWTIVRVSADMLRYRPYDILSRTRNALRASGCPLRSPS
Mvan_5044|M.vanbaalenii_PYR-1 HDIDRQAALEAEGWRIIRVSAEILRDRPTTIVSRVWLALRAAGAPVQPPN
MSMEG_5314|M.smegmatis_MC2_155 WDIDRQAMLEALGWTVIRVSAGLLHGRRQVVVDRVRAALLARGCRMGPGR
Mflv_1289|M.gilvum_PYR-GCK KDIARLRMLEERGWSVVRVIAEDM---PAAWLRRVADALRRKGCPLAWVA
. * * ** ::*: : : :. *:
Mb3585c|M.bovis_AF2122/97 ------------------------------
Rv3555c|M.tuberculosis_H37Rv ------------------------------
MAB_4161|M.abscessus_ATCC_1997 ------------------------------
TH_3487|M.thermoresistible__bu RLDARLEP----------------------
MMAR_4658|M.marinum_M ------------------------------
MUL_0276|M.ulcerans_Agy99 ------------------------------
MAV_1002|M.avium_104 VDLLGTTQPISPNKSTFGGKGRPFGGKGRP
Mvan_5044|M.vanbaalenii_PYR-1 LNL---------------------------
MSMEG_5314|M.smegmatis_MC2_155 AERAF-------------------------
Mflv_1289|M.gilvum_PYR-GCK GKTIAA------------------------