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GDIIVGSEALSSGVLTRYALQTSYRKLHRNVYVPRDFSLDARSRARAAWLWSGRTATLAGYSAAAMLGSR WLPDDAPAELARVRHPSPAGIRIHTGVIADDEICRVGGMDCTTPARTAYDLGRRLPVETGAIRLDALLNA TKTDVADVMSVAERYRGARGIRRLRTTLDLVDPGAESPQETRLRLVLVRAGLPRPVTQIPVLDERGRVRR RIDMGWPDRMVGAEYDGAHHWQDPAAHASDIDRLEFLAAPGWTIIRVSHEHLRYRTPAVIARVRDALKCA EATVVRANS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0914 | - | - | 100% (290) | hypothetical protein MSMEG_0914 |
| M. smegmatis MC2 155 | MSMEG_0881 | - | 1e-70 | 52.17% (276) | hypothetical protein MSMEG_0881 |
| M. smegmatis MC2 155 | MSMEG_5314 | - | 5e-70 | 50.37% (270) | hypothetical protein MSMEG_5314 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3546 | - | 5e-69 | 53.12% (256) | hypothetical protein Mb3546 |
| M. gilvum PYR-GCK | Mflv_4792 | - | 2e-56 | 44.49% (272) | hypothetical protein Mflv_4792 |
| M. tuberculosis H37Rv | Rv3517 | - | 5e-69 | 53.12% (256) | hypothetical protein Rv3517 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4161 | - | 4e-69 | 46.50% (286) | hypothetical protein MAB_4161 |
| M. marinum M | MMAR_4658 | - | 3e-72 | 51.47% (272) | hypothetical protein MMAR_4658 |
| M. avium 104 | MAV_1002 | - | 4e-72 | 54.72% (254) | hypothetical protein MAV_1002 |
| M. thermoresistible (build 8) | TH_3487 | - | 2e-73 | 51.09% (274) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0276 | - | 1e-69 | 50.00% (272) | hypothetical protein MUL_0276 |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | 1e-70 | 49.31% (288) | hypothetical protein Mvan_5044 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4161|M.abscessus_ATCC_1997 MGDVPWPLIRSEALTNRVVTGYALR-QFTALYPGIYAPTDAQITPRKRAE
TH_3487|M.thermoresistible__bu MAEG--PFLGSEARAAGLVTRRTLRSRHRLIYQNVYLPVGVQLTAQTRAV
MMAR_4658|M.marinum_M MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIPRGKKLTAVTRAI
MUL_0276|M.ulcerans_Agy99 MEILDWPFRGTEALAAGAVTPHRLRTHFEMVHRNVYIARGKKLTAVTRAI
MAV_1002|M.avium_104 -----------------------------MVHRNVYVRRGQQLTPVTRAV
Mvan_5044|M.vanbaalenii_PYR-1 ----MDPFLGTEALAAGSLTRYRLKTRFELVHRNVYALNREQLTPVQKAR
MSMEG_0914|M.smegmatis_MC2_155 ---MGDIIVGSEALSSGVLTRYALQTSYRKLHRNVYVPRDFSLDARSRAR
Mb3546|M.bovis_AF2122/97 ---MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRAQ
Rv3517|M.tuberculosis_H37Rv ---MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRAQ
Mflv_4792|M.gilvum_PYR-GCK ---MRRPFVGSEALASGALTRSALRWNYRRIFPDVYLPVDVRPTLYDLTV
:. .:* :
MAB_4161|M.abscessus_ATCC_1997 AAWLWSRRKGTIAGISAAALHGTKWLPQQGPVVLIHTNRRAPRGITLWSD
TH_3487|M.thermoresistible__bu AAWLWARRDATVAGLSAAALHGTKWIDPALPAELIRPSPGSPDGIVIHRD
MMAR_4658|M.marinum_M AAWLWSGRSATAVGLSAAALHRTGWIDDWLPAELNRRGRDKARGIISHSA
MUL_0276|M.ulcerans_Agy99 AAWLWSGRSATAVGLSPAPLHRTGWIDDWLPAELNRRGRDKARDIISHSA
MAV_1002|M.avium_104 AAWLWSGRTATLAGLSAAALHRTAWIDDWLPAELNRAGRDKARGIILHSD
Mvan_5044|M.vanbaalenii_PYR-1 AAWLWSGRRGTLVGLSAAAVLGSRWIDARLPAELNQRSQHKTPGIVLRAD
MSMEG_0914|M.smegmatis_MC2_155 AAWLWSGRTATLAGYSAAAMLGSRWLPDDAPAELARVRHPSPAGIRIHTG
Mb3546|M.bovis_AF2122/97 AAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWSD
Rv3517|M.tuberculosis_H37Rv AAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWSD
Mflv_4792|M.gilvum_PYR-GCK AAWLWSGRRGVIAGAAASALHGSRWVVPTVPIEMIWQNGRPPPGIVVRNE
*****: * .. .* :.:.: : *: . : . .*
MAB_4161|M.abscessus_ATCC_1997 SLPEGERMFVDGLPVTTPARTAFDIGRRTPVDLAVQHLDALMNATRLSRT
TH_3487|M.thermoresistible__bu RLEPGEVCTLRGIPVTTPARTAYDIGRRQTLTRAVVRLDALANATGLTAD
MMAR_4658|M.marinum_M CLDEDEVCVRDGIALTTPARTAFDLGRRKGLTTAVIRLDALTRATELKVA
MUL_0276|M.ulcerans_Agy99 CLDEDEVCVRDGIALTTPARTAFDLGRRKGLTTAVIRLDALTRATELKVA
MAV_1002|M.avium_104 TLCDDETTMRDGMSLTTPARTAFDLGRRKGLTTAVIRLDALMHASDVKTA
Mvan_5044|M.vanbaalenii_PYR-1 TLGPDEIVTARGMPVTSPARTAFDLGRRRGLTLAVIRMDALMRTTGATTS
MSMEG_0914|M.smegmatis_MC2_155 VIADDEICRVGGMDCTTPARTAYDLGRRLPVETGAIRLDALLNATKTDVA
Mb3546|M.bovis_AF2122/97 RVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKLA
Rv3517|M.tuberculosis_H37Rv RVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKLA
Mflv_4792|M.gilvum_PYR-GCK RIDGDETCVRGGMLVTTPERTAFDLARHLRRDQAVARLDALANATEVKAV
: .* *: *:* *** *:.*: .. :*** .::
MAB_4161|M.abscessus_ATCC_1997 DIETVATHHRGARGLHHLANVLGLVDGGAESPWETRTRLLVVRAGFPAPQ
TH_3487|M.thermoresistible__bu AVTAVIDRRRGARGLVRLRRAVGLMDGGAASPPETRTRLLLLAAGFPRPR
MMAR_4658|M.marinum_M DVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLVIRSGLPAPQ
MUL_0276|M.ulcerans_Agy99 DVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIRLLIIRSGLPAPQ
MAV_1002|M.avium_104 DVELLADRHRGARGLVQLRRVLTLVDGGAESPYETKTRLLLAGSGLPRPQ
Mvan_5044|M.vanbaalenii_PYR-1 DIATLLTRHKGARGLVQLRRALELVDPASESPQESRTRLLLVKAGLPPER
MSMEG_0914|M.smegmatis_MC2_155 DVMSVAERYRGARGIRRLRTTLDLVDPGAESPQETRLRLVLVRAGLPRPV
Mb3546|M.bovis_AF2122/97 DVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRPQ
Rv3517|M.tuberculosis_H37Rv DVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRPQ
Mflv_4792|M.gilvum_PYR-GCK DVLALAERHPAARGIRRAVAALSLMDGGAQSPRETWLRLLLVDEWLDPLR
: : : .:**: . .: *:* .: ** *: **:: :
MAB_4161|M.abscessus_ATCC_1997 TQLVVRNRFGDFVARLDMGWPDHKVGIEFDGAQHWTSAQQRTRDIDRATE
TH_3487|M.thermoresistible__bu TQVVVCDPFGYFIGRIDIGWPEYRVGVEYDGAWHWADAAAHAQTIDRVAD
MMAR_4658|M.marinum_M TEIKVLDDWGAVAARIGMGWPECKVGVEFDSAGQWNN-AARSDAVDRSAE
MUL_0276|M.ulcerans_Agy99 TEIKVLDDRGAVAARIGMGWPECKVGVEFDSAGQWNN-AARSDAFDRSAE
MAV_1002|M.avium_104 TQIEVRNEWGAVLARIDMGWEEWKVGVEFDGAQHWTDPAQRTRDIDRFAE
Mvan_5044|M.vanbaalenii_PYR-1 SQIDVFDRDGYHVGRVDMGWETWKVGVEYEGEQHWTNPEQYAHDIDRQAA
MSMEG_0914|M.smegmatis_MC2_155 TQIPVLDERGRVRRRIDMGWPDRMVGAEYDGAHHWQDPAAHASDIDRLEF
Mb3546|M.bovis_AF2122/97 TQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAEA
Rv3517|M.tuberculosis_H37Rv TQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAEA
Mflv_4792|M.gilvum_PYR-GCK TQVEVGD--GRTTVHLDLGYDEPRIGLEYEGSHHSEDRRTYVHDIGRTEF
::: * : * :.:*: :* :::. : . . *
MAB_4161|M.abscessus_ATCC_1997 LVDEGWRIIRVSSDMVRHRSGTILARVAEAFVAA----RAA---------
TH_3487|M.thermoresistible__bu LEEQGWIIIRISRDILRYRPGVFLARVRNALRAHGWPDHASVRLDARLEP
MMAR_4658|M.marinum_M LEARGWTIVRVNAQTLKNRPDIVVAQVRHALVR-----RT----------
MUL_0276|M.ulcerans_Agy99 LEARGWTIVRVNTQTLKNRPDIVVTQVRHALVR-----RT----------
MAV_1002|M.avium_104 LEARGWTIVRVSADMLRYRPYDILSRTRNALRASGCPLRSPSVDLLGTTQ
Mvan_5044|M.vanbaalenii_PYR-1 LEAEGWRIIRVSAEILRDRPTTIVSRVWLALRAAGAPVQPPNLNL-----
MSMEG_0914|M.smegmatis_MC2_155 LAAPGWTIIRVSHEHLRYRTPAVIARVRDALKCAEATVVRANS-------
Mb3546|M.bovis_AF2122/97 LTELGWTDVRVTVEDT---EGGIIWRVSAAWQRRT---------------
Rv3517|M.tuberculosis_H37Rv LTELGWTDVRVTVEDT---EGGIIWRVSAAWQRRT---------------
Mflv_4792|M.gilvum_PYR-GCK IERHGWVAIKVVKEHS---PEFIRFRVREAFARRGVTPRLRSGSRNRQRP
: ** ::: : . :. *
MAB_4161|M.abscessus_ATCC_1997 ----------------------
TH_3487|M.thermoresistible__bu ----------------------
MMAR_4658|M.marinum_M ----------------------
MUL_0276|M.ulcerans_Agy99 ----------------------
MAV_1002|M.avium_104 PISPNKSTFGGKGRPFGGKGRP
Mvan_5044|M.vanbaalenii_PYR-1 ----------------------
MSMEG_0914|M.smegmatis_MC2_155 ----------------------
Mb3546|M.bovis_AF2122/97 ----------------------
Rv3517|M.tuberculosis_H37Rv ----------------------
Mflv_4792|M.gilvum_PYR-GCK RP--------------------