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MGRVFIGSEALAAGALTRSALRWNYRRILPDVYVPAASQLSLRDRTIAAWLWSGRGAVVAGAAAAALHGA KWVDAEVPIELIWRCGRPPPGVVVRNERIDGDEVTGVAGMLVTTPERTAFDLARHLRRNPAVARLDALAN ATDVKAVDVLTLAQRYPGARGMRRAVKSLSLMDGGAQSPRESRLRLLLVDTWLDPVRTQIKVGEGRDVAY LDMGYDEPMIGLDYEGAHHNEDRKTYVYDIGRAERIESRGWIDIKVVKEHSSEFIQARVTEAFARRGYTP RLRPLPRKRRRRRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1656 | - | - | 100% (294) | hypothetical protein Mvan_1656 |
| M. vanbaalenii PYR-1 | Mvan_1730 | - | 2e-71 | 50.36% (278) | hypothetical protein Mvan_1730 |
| M. vanbaalenii PYR-1 | Mvan_5526 | - | 1e-56 | 44.60% (278) | hypothetical protein Mvan_5526 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3546 | - | 1e-66 | 49.64% (274) | hypothetical protein Mb3546 |
| M. gilvum PYR-GCK | Mflv_4792 | - | 1e-125 | 73.47% (294) | hypothetical protein Mflv_4792 |
| M. tuberculosis H37Rv | Rv3517 | - | 1e-66 | 49.64% (274) | hypothetical protein Rv3517 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2184 | - | 2e-65 | 46.05% (291) | hypothetical protein MAB_2184 |
| M. marinum M | MMAR_0375 | - | 1e-69 | 50.00% (276) | hypothetical protein MMAR_0375 |
| M. avium 104 | MAV_4752 | - | 4e-69 | 50.54% (279) | hypothetical protein MAV_4752 |
| M. smegmatis MC2 155 | MSMEG_0850 | - | 4e-77 | 55.47% (274) | hypothetical protein MSMEG_0850 |
| M. thermoresistible (build 8) | TH_4125 | - | 2e-97 | 64.03% (278) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 2e-68 | 49.28% (276) | hypothetical protein MUL_4737 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2184|M.abscessus_ATCC_1997 ----------MAAVFVGSEAVSAGQLTRHELQRFYRPIFRGVYLPKSAEP
MSMEG_0850|M.smegmatis_MC2_155 ----------MGEVVIGGEALAKGLVTRNDLRHHYRRLFPGVYVR--GEP
MMAR_0375|M.marinum_M MDAREARAARSEDVFVGSEAVRRGRLSPYRLRTEFRAIYPDVYLPAHAAP
MUL_4737|M.ulcerans_Agy99 MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLPAHAAP
MAV_4752|M.avium_104 ---------MGEAPVVGSEELASGRLNRHRLRVAYRPVFPNVYLPAQVEP
Mvan_1656|M.vanbaalenii_PYR-1 ----------MGRVFIGSEALAAGALTRSALRWNYRRILPDVYVPAASQL
Mflv_4792|M.gilvum_PYR-GCK ----------MRRPFVGSEALASGALTRSALRWNYRRIFPDVYLPVDVRP
TH_4125|M.thermoresistible__bu ----------MREVFIGSAALRGGGLTRGRLRWNYRAMYPDVYVAKDRPP
Mb3546|M.bovis_AF2122/97 ----------MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADL
Rv3517|M.tuberculosis_H37Rv ----------MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADL
.:*. : * :. *: : : .**:
MAB_2184|M.abscessus_ATCC_1997 TLRDRTVAAWLASGRRGVVAGLAASNLHGASWVDHDVPIELVGVKCRQQE
MSMEG_0850|M.smegmatis_MC2_155 TLRDRTVGAWLWSGRRGVLAGVAASALHGSAWVDPDVPIELIWRNGRPPA
MMAR_0375|M.marinum_M SFRTRCKAAWLWTGRRGVLAGLAAAGLHGSDWIGDDEPVELIWRNPHPPA
MUL_4737|M.ulcerans_Agy99 SFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRNPHPPA
MAV_4752|M.avium_104 TLPLRIRAAWLWSGRTAVIAGAAAAAVHGAAWIPDAVPIELIHHNTRAPD
Mvan_1656|M.vanbaalenii_PYR-1 SLRDRTIAAWLWSGRGAVVAGAAAAALHGAKWVDAEVPIELIWRCGRPPP
Mflv_4792|M.gilvum_PYR-GCK TLYDLTVAAWLWSGRRGVIAGAAASALHGSRWVVPTVPIEMIWQNGRPPP
TH_4125|M.thermoresistible__bu TLRQFIVGAWLWSGREGVITGRAAAALHGAKYVDDATPIELIWKAGRPPP
Mb3546|M.bovis_AF2122/97 TAWSRAQAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPA
Rv3517|M.tuberculosis_H37Rv TAWSRAQAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPA
: .*** : * .*: * :*: :**: :: . *:: :
MAB_2184|M.abscessus_ATCC_1997 GLIARNERIGADEITRISGLPVTHRVRTAFDLGRYQPRTRAMGCLDALMR
MSMEG_0850|M.smegmatis_MC2_155 GLIVRNETLAADEVMRVAGLPVTTPARTAFDLARHLPRDEAVARIDALAW
MMAR_0375|M.marinum_M GVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARLDALMR
MUL_4737|M.ulcerans_Agy99 GVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARLDALMR
MAV_4752|M.avium_104 GVLIRRDGLCPGETQICDGLAVTTPERTAFDIGRRGAVRSAVVRLDSLAR
Mvan_1656|M.vanbaalenii_PYR-1 GVVVRNERIDGDEVTGVAGMLVTTPERTAFDLARHLRRNPAVARLDALAN
Mflv_4792|M.gilvum_PYR-GCK GIVVRNERIDGDETCVRGGMLVTTPERTAFDLARHLRRDQAVARLDALAN
TH_4125|M.thermoresistible__bu RIIVRNERLDAADVTTVDDMLVTTPARTAFDLARHLPRDAAVRHLDALAG
Mb3546|M.bovis_AF2122/97 GIHTWSDRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALAR
Rv3517|M.tuberculosis_H37Rv GIHTWSDRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALAR
: : : : .: .* ***:*:.* :: :*:*
MAB_2184|M.abscessus_ATCC_1997 NQVFALDEVAGLSQRYPKVRGVRQLRELLPLIDAGAQSPRESLIRLQLRD
MSMEG_0850|M.smegmatis_MC2_155 TRRVTVDDVAALIERYPAARGIRAARAVLRLVDAGADSPRETWLRLRLTD
MMAR_0375|M.marinum_M ATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRETWLRMVLID
MUL_4737|M.ulcerans_Agy99 ATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLRMVLID
MAV_4752|M.avium_104 ATGFKADDVLRVAGAHPRSPGLRRLEAALGLVDPGAQSPRESYLRLLLID
Mvan_1656|M.vanbaalenii_PYR-1 ATDVKAVDVLTLAQRYPGARGMRRAVKSLSLMDGGAQSPRESRLRLLLVD
Mflv_4792|M.gilvum_PYR-GCK ATEVKAVDVLALAERHPAARGIRRAVAALSLMDGGAQSPRETWLRLLLVD
TH_4125|M.thermoresistible__bu ATGVCAADVLPLADRYRRARGLPRARVALDLMDGGAQSPRETRLRLILVD
Mb3546|M.bovis_AF2122/97 ATDLKLADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIR
Rv3517|M.tuberculosis_H37Rv ATDLKLADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIR
. :* : : *: * *:* ** ****: :*: *
MAB_2184|M.abscessus_ATCC_1997 AGLPRAQTQVPVFDG-YTPIAFLDIGWPQYLVAVEYDGDHHRRDRRQYVK
MSMEG_0850|M.smegmatis_MC2_155 AGLPPDSTQIPVVDERGRIVAILDMGWERHLVAVNYDGVFHQSDRKRYVR
MMAR_0375|M.marinum_M AGLPVPVTQIPVHQN-WRLVAVLDMGWQKYQVAAEYDGDQHRFDRRQYAR
MUL_4737|M.ulcerans_Agy99 AGLPVPVTQIPVHQN-WRLVAVLDMGWQKYQVAAEYDGDQHRFDRRQYAR
MAV_4752|M.avium_104 AGLPRPQTQVPVPGADGLPVAYLDMGWPEWMVAVEYDGDHHRTDRRQYVK
Mvan_1656|M.vanbaalenii_PYR-1 TWLDPVRTQIKVGE--GRDVAYLDMGYDEPMIGLDYEGAHHNEDRKTYVY
Mflv_4792|M.gilvum_PYR-GCK EWLDPLRTQVEVGD--GRTTVHLDLGYDEPRIGLEYEGSHHSEDRRTYVH
TH_4125|M.thermoresistible__bu DGLPRPRTQIGVSD--GVNEAFIDMGWDEPMVGLDYEGAHHSADRRQYVH
Mb3546|M.bovis_AF2122/97 AGFPRPQTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNK
Rv3517|M.tuberculosis_H37Rv AGFPRPQTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNK
: **: * . :*:*: :. :*:* * **: :
MAB_2184|M.abscessus_ATCC_1997 DLARLRMLEERGWTVIRVIAEESPGAWIARTTAALRSRGCHIEIDEMQRS
MSMEG_0850|M.smegmatis_MC2_155 DLKTLRALEDRGWIVIRVVAEDDIADVITRVAAAP------------WLA
MMAR_0375|M.marinum_M DQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALA-----------RRG
MUL_4737|M.ulcerans_Agy99 EQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALA-----------RRG
MAV_4752|M.avium_104 DIRRLEMLEQLGWVIVRVVAEDRPADIVRRVRAALAKS---------GVA
Mvan_1656|M.vanbaalenii_PYR-1 DIGRAERIESRGWIDIKVVKEHSSEFIQARVTEAFARRGYTPRLRPLPRK
Mflv_4792|M.gilvum_PYR-GCK DIGRTEFIERHGWVAIKVVKEHSPEFIRFRVREAFARRGVTPRLRSGSRN
TH_4125|M.thermoresistible__bu DIGRAELIVGQGWLDIRVVAEHSRRFILHRTREAFARRG-----------
Mb3546|M.bovis_AF2122/97 DIKRAEALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------
Rv3517|M.tuberculosis_H37Rv DIKRAEALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------
: . : ** ::* . *. *
MAB_2184|M.abscessus_ATCC_1997 TRPFAA-
MSMEG_0850|M.smegmatis_MC2_155 PRLH---
MMAR_0375|M.marinum_M HRET---
MUL_4737|M.ulcerans_Agy99 HRET---
MAV_4752|M.avium_104 PRLSV--
Mvan_1656|M.vanbaalenii_PYR-1 RRRRRP-
Mflv_4792|M.gilvum_PYR-GCK RQRPRP-
TH_4125|M.thermoresistible__bu WHLPKPV
Mb3546|M.bovis_AF2122/97 -------
Rv3517|M.tuberculosis_H37Rv -------