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M. vanbaalenii PYR-1 Mvan_5030 (-)

annotation: glycoside hydrolase family protein
coordinates: 5382544 - 5385201
length: 885

KSAQVVGRVGALAVALGVGAAVFTGSGVAWATEDAAGETTAESGATTSEPADDGDAVEPADDGDTVEQVE
SDDDDEAVGQVEPEEEAEADEDEAVVEPDEDEVAPDVEEAADADGAPSEDGDGGFQVPAAPREDDAPPTE
PDEDTGSAAAVASSETGSSEADGVEPAVDTVAVQRLTVEPTAAVSTTVASPPEVPSWRPWPTAFDLRSAV
TYVVDLATSFVDALLSPFAAGPPRPPADPSGWALLAWVRREFFNGTPAPVENPLPHTQSLTADGGVVITG
NVGVVDPDGDALTYSVIGRPHNGGTVAVDADGNFVYRPMNAMAAVGGTDTFTVAVSDEHDGLHVHGLFGW
LQFVPILGNLLNPGGGHGRTVTIAVTVTPVDGIDLSLPDDFRWGVAHSGFQAEGGPGSPVDTRSDWYRWV
HDPVNRLLGLVKGVPEDGPGAYVSYDGDAALARDELGMNTFRMGIEWSRIFPESTAAVDISDEGGALSLA
DLEALDELADQDEVAHYRAVFAALRRRGLDPFVTVNHFTLPVWVHDPIVARPLIQLGLPAPAAGWLSSNT
AEEFEKYAAYVAWKYGDQVDNWATLNEPFPPVLTEFLAIPWVVPNWPPGVLRPDLASTFVVNQAIGHVAA
YDAIHTWDTTAAAADGPAAFVGFTHNMIPARPANPVNPLDVQAADAWNHFYNKWFPNAVIDGWVDANFDG
VKTADEIHPEMAGKVDFLGVQYYGSQPMVGFGVAPLPGFPFLRGFPIRCSGEEPTCSDFNQPTDPGGFRE
VLELAGSYGKPLWVTENGIADADDSKRPSYIVNHVAVVQDLVAHGADIRGYTYWSFVDNLEWSEGYELQF
GLYGSDPETPELERIPKPASIAALSGITTANGLPVSLLQTYIPS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5030--100% (885)glycoside hydrolase family protein
M. vanbaalenii PYR-1Mvan_1597-6e-3631.90% (395) hypothetical protein Mvan_1597
M. vanbaalenii PYR-1Mvan_5057-4e-3230.15% (544) hypothetical protein Mvan_5057

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0912-5e-0936.36% (132) hypothetical protein Mb0912
M. gilvum PYR-GCKMflv_1722-0.073.90% (889) glycoside hydrolase family protein
M. tuberculosis H37RvRv0888-5e-0936.36% (132) hypothetical protein Rv0888
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3192c-3e-2726.67% (510) putative glycosyl hydrolase (beta-glucosidase)
M. marinum MMMAR_2416lgt1e-0829.52% (166) prolipoprotein diacylglyceryl transferases Lgt
M. avium 104MAV_3172-5e-0631.25% (112) prolipoprotein diacylglyceryl transferase
M. smegmatis MC2 155MSMEG_5142-2e-3829.73% (528) beta-glucosidase A
M. thermoresistible (build 8)TH_0997rne7e-0626.26% (198) POSSIBLE RIBONUCLEASE E RNE
M. ulcerans Agy99MUL_3715rne2e-0628.10% (153) ribonuclease E Rne

CLUSTAL 2.0.9 multiple sequence alignment


Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           PAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDADDE
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEA
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          ------------MGGGTWRSQSTDRHLASDAVGRGAVRQVCRVGADGVRQ
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           PQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKS
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            -------------------MDYAKRIGQVGALAVVLGVGAAVTT-HAIGS
Rv0888|M.tuberculosis_H37Rv         -------------------MDYAKRIGQVGALAVVLGVGAAVTT-HAIGS
Mvan_5030|M.vanbaalenii_PYR-1       -------------------MKSAQVVGRVGALAVALGVGAAVFTGSGVAW
Mflv_1722|M.gilvum_PYR-GCK          NDGFGQSAHRAARRRYSRFMDSAQFVGRVGGLAVALGVGAALVTGSGVAW
MMAR_2416|M.marinum_M               -------------MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIGIVM
MAV_3172|M.avium_104                --------------MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAGIVA
TH_0997|M.thermoresistible__bu      ---------VSPDDPPNTVVHERVPRTEKEER------DQAHSEIQGITG
MUL_3715|M.ulcerans_Agy99           GAGDDGDEGPAPDDPPNTVVHERAPRSGDKSGNSDSGDDSGGNEIKGIDG
MSMEG_5142|M.smegmatis_MC2_155      ----------------------------MSQPDRTLGFPDGFVWGTATAS
MAB_3192c|M.abscessus_ATCC_199      ----MKWMNAVMASAAVVALGLTACSPRQEAPKEDAGWDRGFYWGTATAG
                                                                            .     .   

Mb0912|M.bovis_AF2122/97            AAPTDPSSSSTDSPVDACSPLGGSASSLAAIPGASVPQVGVRQVD-----
Rv0888|M.tuberculosis_H37Rv         AAPTDPSSSSTDSPVDACSPLGGSASSLAAIPGASVPQVGVRQVD-----
Mvan_5030|M.vanbaalenii_PYR-1       ATEDAAGETTAESGATTSEPADDGDAVEPADDGDTVEQVESDDDDEAVGQ
Mflv_1722|M.gilvum_PYR-GCK          ATEDSG--SSASAGAESSTARTSSQDRQAASPSKPARDRAGGRDDAEGGG
MMAR_2416|M.marinum_M               GLMIGDRRFAARGGERGVIYDIALWMVPFGLIGGRLYHLSTDWQTYFG--
MAV_3172|M.avium_104                ALLIGDRRWEARGGERGVIYDIALWTVPFGLVGGRLYHLATDWRTYWG--
TH_0997|M.thermoresistible__bu      STRLEAKRQRRRDGRDAGRRRPPILSEAEFLARREAVERVMVVRDKVR--
MUL_3715|M.ulcerans_Agy99           STRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVR--
MSMEG_5142|M.smegmatis_MC2_155      YQIEGAVTAGGRAPSIWDTFSHKPGAVHNGDNGDVADDHYHRYREDVG--
MAB_3192c|M.abscessus_ATCC_199      YQVEGSAPDSNWRRYVERSAGKPVHPDESNLLADGPVDPYKQADDFRHR-
                                                                         .            

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       VEPEEEAEADEDEAVVEPDEDEVAPDVEEAADADGAPSEDGDGGFQVPAA
Mflv_1722|M.gilvum_PYR-GCK          AE-DRDAQAQDD-ATPETGGETGAPD-DASVDASG-PDTGGTTGDASAED
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       PREDDAPPTEPDEDTGSAAAVASSETGSSEADGVEPAVDTVAVQRLTVEP
Mflv_1722|M.gilvum_PYR-GCK          DDPDEAEERAAWADTGADTDADPDADPDADAS-AATDVATAAVP-SGAGP
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            -----------PGSIP-----------DDLLNALIDFLAAVRNGLVPIIE
Rv0888|M.tuberculosis_H37Rv         -----------PGSIP-----------DDLLNALIDFLAAVRNGLVPIIE
Mvan_5030|M.vanbaalenii_PYR-1       TAAVSTTVAS-PPEVPSWRPWPTAFDLRSAVTYVVDLATSFVDALLSPFA
Mflv_1722|M.gilvum_PYR-GCK          TAVVTTEVTVDPPRVPSWRPWPTAFDLRGAVTYVVDLAVSVVDALFHPFA
MMAR_2416|M.marinum_M               -----------EGGAGLG---AALRIWDGGLGIWGAVTLGTVGAWIGCRR
MAV_3172|M.avium_104                -----------PGGAGFG---AAVRIWDGGLGIWGAVALGAVGAWIGCRR
TH_0997|M.thermoresistible__bu      -----------TEPPHQGARYTQIAVLEDGVVVEHFVTSSASASLVGNIY
MUL_3715|M.ulcerans_Agy99           -----------TEPPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIY
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------LLADLGVTHYRFSLAWPR
MAB_3192c|M.abscessus_ATCC_199      --------------------------YAEDIANAHAMGVNTFRFGLEWSR
                                                                        .        .    

Mb0912|M.bovis_AF2122/97            NRTP--------------------------VANPQ---QVSVPEGGTVGP
Rv0888|M.tuberculosis_H37Rv         NRTP--------------------------VANPQ---QVSVPEGGTVGP
Mvan_5030|M.vanbaalenii_PYR-1       AGPPRPPADPSGWALLAWVRREFFNGTPAPVENPLPHTQSLTADGGVVIT
Mflv_1722|M.gilvum_PYR-GCK          AGPPPPPGDPSAWGLLAWVRRELFNSTPDEVDNPLPYTQSL-VDGDVVIT
MMAR_2416|M.marinum_M               RGIPLP-----------------------AFLDAVAPGVVMGQAIG----
MAV_3172|M.avium_104                HGIPLP-----------------------AFADALAPGIILAQAIG----
TH_0997|M.thermoresistible__bu      LGIVQN-----------------------VLPSMEAAFVDIGRGRNGVLY
MUL_3715|M.ulcerans_Agy99           LGIVQN-----------------------VLPSMEAAFVDIGRGRNGVLY
MSMEG_5142|M.smegmatis_MC2_155      LQPDGK--------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      VMPEP---------------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            VRFDACDPDGNRMTFAVRERGAPGGPQHGIVTVDQRTASFIYTADPGFVG
Rv0888|M.tuberculosis_H37Rv         VRFDACDPDGNRMTFAVRERGAPGGPQHGIVTVDQRTASFIYTADPGFVG
Mvan_5030|M.vanbaalenii_PYR-1       GNVGVVDPDGDALTYSVIGRPHNGG--TVAVDADGNFVYRPMNAMAAVGG
Mflv_1722|M.gilvum_PYR-GCK          GNVGVEDRDGDPLTYEVIGRPRFGG--EVTVDADGNFVYRPMNAMAAVGG
MMAR_2416|M.marinum_M               -RLGNYFNQELYGRETTVPWGLE------IFYRRDPSGFVDVHSLDGVST
MAV_3172|M.avium_104                -RLGNYFNQELYGRETTLPWGLE------IFYRRDPSGYIDPHSLDGVST
TH_0997|M.thermoresistible__bu      AGEVNWEAAGLGGQNRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQLSL
MUL_3715|M.ulcerans_Agy99           AGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGHKGARLTTQVSL
MSMEG_5142|M.smegmatis_MC2_155      ---GPINTEGLDFYQR-------------LVDELLAHDIQPWVTLYHWDL
MAB_3192c|M.abscessus_ATCC_199      ---GKWDEKELAYYDS-------------VVATLRENGMTPMITLMHWVY
                                                                                      

Mb0912|M.bovis_AF2122/97            TDTFSVNVS-----------DDTS-LHVHGLAGYLG----------PFHG
Rv0888|M.tuberculosis_H37Rv         TDTFSVNVS-----------DDTS-LHVHGLAGYLG----------PFHG
Mvan_5030|M.vanbaalenii_PYR-1       TDTFTVAVS-----------DEHDGLHVHGLFGWLQFVPILGNLLNPGGG
Mflv_1722|M.gilvum_PYR-GCK          TDEFTVAVT-----------DDAAGLHVHGLLGWLQFVPILGSFLNPGGG
MMAR_2416|M.marinum_M               GQVAVVVQP----------------TFLYELIWNLLVFAALIYLDRR---
MAV_3172|M.avium_104                GQVALVVQP----------------TFLYELLWNLLIFVALLYADRR---
TH_0997|M.thermoresistible__bu      AGRYLVYVPGATSTGISRKLPDTERQRLKEILREVVPPDAGVIIRTASEG
MUL_3715|M.ulcerans_Agy99           AGRYLVYVAGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEG
MSMEG_5142|M.smegmatis_MC2_155      PQTLEDAGG-----------------------------------------
MAB_3192c|M.abscessus_ATCC_199      PGWVADSGG-----------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            HDDVATVTVFVG----------------------------NTPTDTISGD
Rv0888|M.tuberculosis_H37Rv         HDDVATVTVFVG----------------------------NTPTDTISGD
Mvan_5030|M.vanbaalenii_PYR-1       HGRTVTIAVTVTPVDGIDLSLPDDFRWGVAHSGFQAEGGPGSPVDTRSDW
Mflv_1722|M.gilvum_PYR-GCK          HGITRTITVTVEPVDGIDLSLPDGFKWGVAHSGFQAEGGPGSPVDTGSDW
MMAR_2416|M.marinum_M               ------FTIGHGRLFASY------------------VALYCVGRFCVELL
MAV_3172|M.avium_104                ------LTLGHGRLFALY------------------VAGYCVGRFCVELL
TH_0997|M.thermoresistible__bu      V-KEEDIRADVNRLQERWTQIEAKAAELTEKKAGQAVALYEEPDVLVKVI
MUL_3715|M.ulcerans_Agy99           V-KEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEEPDVLVKVI
MSMEG_5142|M.smegmatis_MC2_155      ---------------------------------WPARDTAQRFADYAAMT
MAB_3192c|M.abscessus_ATCC_199      ---------------------------------------FMNNLPAFEEF
                                                                                      

Mb0912|M.bovis_AF2122/97            FSMLTYNIAGLPFPLS----------------------------------
Rv0888|M.tuberculosis_H37Rv         FSMLTYNIAGLPFPLS----------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       YRWVHDPVNRLLGLVKGVPEDGPGAYVSYDGDAALARDELGMNTFRMGIE
Mflv_1722|M.gilvum_PYR-GCK          YRWVHDPLNRLLGLVKGVPENGPGAYVSYEDDARLAREELGVNTFRMGIE
MMAR_2416|M.marinum_M               RDDTATHIAGIRIN---SFTSTFVFIGAVVYIILAPKGREDPASVR----
MAV_3172|M.avium_104                RDDTATHIAGIRIN---SFTSTFVFIGAVVYLMAAPKGREDPESLR----
TH_0997|M.thermoresistible__bu      RDLFNEDFSRLIVSGDHAWNTINEYVSTVAPDLMPRLTKYEPASED----
MUL_3715|M.ulcerans_Agy99           RDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQV
MSMEG_5142|M.smegmatis_MC2_155      HGKLHDRIR-----------------------------------------
MAB_3192c|M.abscessus_ATCC_199      AKAITKRYAG----------------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            -SAILPRFFYTKEIGKR--------LNAYYVANVQEDFAYHQFLIKKSKM
Rv0888|M.tuberculosis_H37Rv         -SAILPRFFYTKEIGKR--------LNAYYVANVQEDFAYHQFLIKKSKM
Mvan_5030|M.vanbaalenii_PYR-1       WSRIFPESTAAVDISDEGGALSLADLEALDELADQDEVAHYRAVFAALRR
Mflv_1722|M.gilvum_PYR-GCK          WSRIFPDSTASVDISDEGGTVSLADLQALDALANADEVAHYRDVFAALRF
MMAR_2416|M.marinum_M               -----GTAAAAEEVPEPEPAGEVATAAAPAGDTEGDEPTGLAETAKAAEV
MAV_3172|M.avium_104                -----GNQYVEEEPAEPEPATVAATTEAAT--------EGVAAPADG---
TH_0997|M.thermoresistible__bu      GPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTG
MUL_3715|M.ulcerans_Agy99           GPDVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTG
MSMEG_5142|M.smegmatis_MC2_155      ---------HWTTLNEPWCSAFLGYAAGAHAPGRTEPAAALAAAHHLMFG
MAB_3192c|M.abscessus_ATCC_199      ------QGVLWVSINEPLAFGAMEVRTGAIKPDQFNGFLDRVADAHRAVY
                                                   .           .                      

Mb0912|M.bovis_AF2122/97            PSQTP---------------PEPPTLLWPIGVPFSDG----LNTLSEFKV
Rv0888|M.tuberculosis_H37Rv         PSQTP---------------PEPPTLLWPIGVPFSDG----LNTLSEFKV
Mvan_5030|M.vanbaalenii_PYR-1       RGLDPFVTVNHFTLPVWVHDPIVARPLIQLGLPAPAAGWLSSNTAEEFEK
Mflv_1722|M.gilvum_PYR-GCK          HGLDPMVTVNHFTLPVWVHDPVLARPLIQLGLPVAAAGWLSTETAVEFEK
MMAR_2416|M.marinum_M               AEPETVGSAVAGDESTADTEASDAVESEVGEAAEAEAPEAEAEEAEVGEV
MAV_3172|M.avium_104                -----------------------------AEAAGADATAQRPEESAEPDV
TH_0997|M.thermoresistible__bu      SGGNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVL
MUL_3715|M.ulcerans_Agy99           SGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVL
MSMEG_5142|M.smegmatis_MC2_155      HG---------------------------LAVAAMRAQDGDSQLGITVNL
MAB_3192c|M.abscessus_ATCC_199      R-------------------------------AAHEADPEAKVTTNEAYI
                                                                                      

Mb0912|M.bovis_AF2122/97            QRLDRQTWYECTSDNCLTLKG---------------------------FT
Rv0888|M.tuberculosis_H37Rv         QRLDRQTWYECTSDNCLTLKG---------------------------FT
Mvan_5030|M.vanbaalenii_PYR-1       YAAYVAWKYGDQVDNWATLNEPFPPVLTEFLAIPWVVPNWPPGVLRPDLA
Mflv_1722|M.gilvum_PYR-GCK          YAAYLAWKYGDQVDNWATLNEPFPPVLTEFLAIPWVVPNWPPGVLRPDLA
MMAR_2416|M.marinum_M               E-VAEAVEGEVEEAEEAEPGE---------VEVAEAVEGEVEAAAEAEEA
MAV_3172|M.avium_104                E-KPESEETEAEAAEEPE-------------------------------S
TH_0997|M.thermoresistible__bu      RRLTEALARDRTRHQVSEVTS---------LGLVQLTRKRLGTGLLEAFS
MUL_3715|M.ulcerans_Agy99           RRLTEALARDRTRHQVSEVTS---------LGLVQLTRKRLGTGLIEAFS
MSMEG_5142|M.smegmatis_MC2_155      TPVSPATEEPADVD-----------------------------------A
MAB_3192c|M.abscessus_ATCC_199      PPDVLAQFAGFGVKG---------------------------------IE
                                                                                      

Mb0912|M.bovis_AF2122/97            YSQMRLPGGDTVDVYNLHTNTGGGPTTNANLAQVANYIQQNSAGRAVIVT
Rv0888|M.tuberculosis_H37Rv         YSQMRLPGGDTVDVYNLHTNTGGGPTTNANLAQVANYIQQNSAGRAVIVT
Mvan_5030|M.vanbaalenii_PYR-1       STFVVNQAIGHVAAYDAIHTWDTTAAAADGPAAFVGFTHNMIPARPANPV
Mflv_1722|M.gilvum_PYR-GCK          STFLVNQAIGHVAAYDAIHAWDTTSAVEGGPAAFVGFTHNMIPARPANPV
MMAR_2416|M.marinum_M               EEAEEAEEAEEAEEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEVEAVDEA
MAV_3172|M.avium_104                EETEAAEEPGEPEAEEP-------------------------------EE
TH_0997|M.thermoresistible__bu      TTCTHCNGRGIVLHTDPVDSAQPS-RRSDSGSRRSKRSKRSRSDD----V
MUL_3715|M.ulcerans_Agy99           TSCPHCSGRGILLHADPVDSAPTTGRKADSGGRRNRRSKKNRAEEPSEKE
MSMEG_5142|M.smegmatis_MC2_155      ARRVDAVSNRLFLDALLRGRYPADLSADVAMISDFGFVQPGDEAVIAAPL
MAB_3192c|M.abscessus_ATCC_199      GSFFDRVAGSLDYLGFDYYTGTAADNPASAQSMAARWNIKLQPEDIYYVS
                                                                                      

Mb0912|M.bovis_AF2122/97            GDFNARYSDDQSALLQFAQVNGLTDAWVQVEHGPTTPPFAPTCMVGNECE
Rv0888|M.tuberculosis_H37Rv         GDFNARYSDDQSALLQFAQVNGLTDAWVQVEHGPTTPPFAPTCMVGNECE
Mvan_5030|M.vanbaalenii_PYR-1       NPLDVQAADAWNHFYNKWFPNAVIDGWVDANFDGVKTADEIHPEMAGKVD
Mflv_1722|M.gilvum_PYR-GCK          NALDVGAAEAWNHYYNHWFPNAVIDGWIDLDFDGIKSADEIRPDMADKVD
MMAR_2416|M.marinum_M               AEAEAPEVGEIEAAEAVEGEVEVAAEAEEAEAGEDEPKEAEEVAEAEGSE
MAV_3172|M.avium_104                PEAEEPEE----------------PETEEPEADSDE--------------
TH_0997|M.thermoresistible__bu      QVVKVPPHPPGEHPLFKAMAAASERADSEAKDDTEETGDGGKDAAKVAAK
MUL_3715|M.ulcerans_Agy99           AVAKVPTYAPGEHPMFKAMAASSSSEAEHGDGEVEESGE------ELTAA
MSMEG_5142|M.smegmatis_MC2_155      DFLGVNYYFRETVRFGTGAPSDNPHARAWVGSTDVEPVRTGLPTTAMGWE
MAB_3192c|M.abscessus_ATCC_199      RHYAQRYPGLPIYIVENGMVTDNGKPRADGVTRSQYLSDTVFWLQRAKAD
                                                                                      

Mb0912|M.bovis_AF2122/97            LLDKIFYRSGQGVTLQAVSYG-----------------------------
Rv0888|M.tuberculosis_H37Rv         LLDKIFYRSGQGVTLQAVSYG-----------------------------
Mvan_5030|M.vanbaalenii_PYR-1       FLGVQYYGSQPMVGFGVAPLPGFPFLRGFPIRCS----------------
Mflv_1722|M.gilvum_PYR-GCK          FLGVQYYGSQPMVGFGVAPLPGFPFLRGFPIRCS----------------
MMAR_2416|M.marinum_M               AEDKTVQAIDGGQTGVDDAGEADAEPDDDSTAAEPEVVVEQADIEEIEPQ
MAV_3172|M.avium_104                ------------------------EPE-----------------------
TH_0997|M.thermoresistible__bu      VKEKVAAEDRAKVGAQDGVEEATPDGVETEAAAATRAERVRTAVSGDAQA
MUL_3715|M.ulcerans_Agy99           VDDQTAVQVALDLGETE---------------------------------
MSMEG_5142|M.smegmatis_MC2_155      IDPTGLYDVLSWVHREYGPVP-----------------------------
MAB_3192c|M.abscessus_ATCC_199      GIPIVGYNYWSLVDN-----------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            ---------------------------------NEAPKFFNSKGEPLSDH
Rv0888|M.tuberculosis_H37Rv         ---------------------------------NEAPKFFNSKGEPLSDH
Mvan_5030|M.vanbaalenii_PYR-1       ---------------GEEPTCSDFNQPTDPGGFREVLELAGSYGKPLWVT
Mflv_1722|M.gilvum_PYR-GCK          ---------------AEETTCSDFNQPIDPGGFREVLEVAASYGKPLWVT
MMAR_2416|M.marinum_M               EPEAEAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVDVDATATEAE
MAV_3172|M.avium_104                -------------------------------------------------E
TH_0997|M.thermoresistible__bu      SAGDLDDEDLANGDLEDEYLDDEDEDEDLEDGDLENGDLDDEDDDEDLED
MUL_3715|M.ulcerans_Agy99           ---------------ESEETDGTDETDDFDDDSDDSDDSDEDDDTDETND
MSMEG_5142|M.smegmatis_MC2_155      -------------------------------------IYVTENGAAFDDD
MAB_3192c|M.abscessus_ATCC_199      ---------------------------------------YEWGSYRPRFG
                                                                                      

Mb0912|M.bovis_AF2122/97            SPAVVGFH------YVADNVAVR---------------------------
Rv0888|M.tuberculosis_H37Rv         SPAVVGFH------YVADNVAVR---------------------------
Mvan_5030|M.vanbaalenii_PYR-1       ENGIADADDSKRPSYIVNHVAVVQDLVAHGADIRGYTYWSFVDNLEWSEG
Mflv_1722|M.gilvum_PYR-GCK          ENGIADAGDAKRPPYLVNHVAVVQDLVAHGLDIRGYTYWSFVDNLEWSEG
MMAR_2416|M.marinum_M               ESGDESPEPAADSEEPEADESAPEDSAEDTSSGESDTQSELEQSQTIEQG
MAV_3172|M.avium_104                ESGEAPEQPVAE--EPEPAPQQPE--------------------------
TH_0997|M.thermoresistible__bu      GEIDVDLDEDLDDDIEVLNGDPDDEEADEDVDSYEDPYDADADADSDSDA
MUL_3715|M.ulcerans_Agy99           TDVDADEDEDTDDDSDEDEDTEDDDELDDDLDDELDDDDSDSDDE-DSES
MSMEG_5142|M.smegmatis_MC2_155      AEADGSIRDDDRITFLDSHFRATLRAIDDGADIRGYFVWSLLDNFEWAYG
MAB_3192c|M.abscessus_ATCC_199      LYTVDALGDPALKRVPTDAVATYTQITRDAGTVPGYRPVIPAAKCSTTVG
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       YELQFGLYGSDPETPELERIPKPASIAALSGITTANGLPVSLLQTYIPS-
Mflv_1722|M.gilvum_PYR-GCK          YDLQFGLYGSDPDTPELERIPKVASIAALKGITTANGLPVALLQNYLPG-
MMAR_2416|M.marinum_M               SDQTSAGDGEGPPPSAAVDGDTGPTRQGWRGRLRNRMRRSGR--------
MAV_3172|M.avium_104                ------------------------TKRRWGARLRDRL--SGR--------
TH_0997|M.thermoresistible__bu      DADDEDSGDDRAAGRYAAPTVTRRPRRRAAVRPAGPPVQS----------
MUL_3715|M.ulcerans_Agy99           ELTEPAAG--RPAALEVTTIAERPRRRRAAGRPAGPPIHLG---------
MSMEG_5142|M.smegmatis_MC2_155      YAKRFGLIHVDYATQVRTP---KASARWFAEVTRRNGVPHVFRQNDAPAD
MAB_3192c|M.abscessus_ATCC_199      QDSCAPLDPNGPTVALR---------------------------------
                                                                                      

Mb0912|M.bovis_AF2122/97            --
Rv0888|M.tuberculosis_H37Rv         --
Mvan_5030|M.vanbaalenii_PYR-1       --
Mflv_1722|M.gilvum_PYR-GCK          --
MMAR_2416|M.marinum_M               --
MAV_3172|M.avium_104                --
TH_0997|M.thermoresistible__bu      --
MUL_3715|M.ulcerans_Agy99           --
MSMEG_5142|M.smegmatis_MC2_155      IR
MAB_3192c|M.abscessus_ATCC_199      --