For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_1722 (-)

annotation: glycoside hydrolase family protein
coordinates: 1790275 - 1793079
length: 934

MGGGTWRSQSTDRHLASDAVGRGAVRQVCRVGADGVRQNDGFGQSAHRAARRRYSRFMDSAQFVGRVGGL
AVALGVGAALVTGSGVAWATEDSGSSASAGAESSTARTSSQDRQAASPSKPARDRAGGRDDAEGGGAEDR
DAQAQDDATPETGGETGAPDDASVDASGPDTGGTTGDASAEDDDPDEAEERAAWADTGADTDADPDADPD
ADASAATDVATAAVPSGAGPTAVVTTEVTVDPPRVPSWRPWPTAFDLRGAVTYVVDLAVSVVDALFHPFA
AGPPPPPGDPSAWGLLAWVRRELFNSTPDEVDNPLPYTQSLVDGDVVITGNVGVEDRDGDPLTYEVIGRP
RFGGEVTVDADGNFVYRPMNAMAAVGGTDEFTVAVTDDAAGLHVHGLLGWLQFVPILGSFLNPGGGHGIT
RTITVTVEPVDGIDLSLPDGFKWGVAHSGFQAEGGPGSPVDTGSDWYRWVHDPLNRLLGLVKGVPENGPG
AYVSYEDDARLAREELGVNTFRMGIEWSRIFPDSTASVDISDEGGTVSLADLQALDALANADEVAHYRDV
FAALRFHGLDPMVTVNHFTLPVWVHDPVLARPLIQLGLPVAAAGWLSTETAVEFEKYAAYLAWKYGDQVD
NWATLNEPFPPVLTEFLAIPWVVPNWPPGVLRPDLASTFLVNQAIGHVAAYDAIHAWDTTSAVEGGPAAF
VGFTHNMIPARPANPVNALDVGAAEAWNHYYNHWFPNAVIDGWIDLDFDGIKSADEIRPDMADKVDFLGV
QYYGSQPMVGFGVAPLPGFPFLRGFPIRCSAEETTCSDFNQPIDPGGFREVLEVAASYGKPLWVTENGIA
DAGDAKRPPYLVNHVAVVQDLVAHGLDIRGYTYWSFVDNLEWSEGYDLQFGLYGSDPDTPELERIPKVAS
IAALKGITTANGLPVALLQNYLPG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1722--100% (934)glycoside hydrolase family protein
M. gilvum PYR-GCKMflv_2538-3e-3531.54% (409) peptidase S15
M. gilvum PYR-GCKMflv_0506-1e-3432.74% (391) putative outer membrane adhesin like protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0912-3e-0634.48% (145) hypothetical protein Mb0912
M. tuberculosis H37RvRv0888-3e-0634.48% (145) hypothetical protein Rv0888
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3192c-4e-2726.08% (510) putative glycosyl hydrolase (beta-glucosidase)
M. marinum MMMAR_4644-4e-0727.24% (279) hypothetical protein MMAR_4644
M. avium 104-----
M. smegmatis MC2 155MSMEG_5142-3e-4030.02% (533) beta-glucosidase A
M. thermoresistible (build 8)TH_2316-7e-1233.90% (177) conserved hypothetical protein
M. ulcerans Agy99MUL_3715rne2e-0528.57% (154) ribonuclease E Rne
M. vanbaalenii PYR-1Mvan_5030-0.073.90% (889) glycoside hydrolase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4644|M.marinum_M               --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5030|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
TH_2316|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4644|M.marinum_M               --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          ---------MGGGTWRSQSTDRHLASDAVGRGAVRQVCRVGADGVRQNDG
Mvan_5030|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
TH_2316|M.thermoresistible__bu      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE
                                                                                      

Mb0912|M.bovis_AF2122/97            ----------------MDYAKRIGQVGALAVVLGVGAAVTT-HAIGSAAP
Rv0888|M.tuberculosis_H37Rv         ----------------MDYAKRIGQVGALAVVLGVGAAVTT-HAIGSAAP
MMAR_4644|M.marinum_M               ----------------MGYASHAVRVGALVFVLVVGAAVATDQAIGHAAP
Mflv_1722|M.gilvum_PYR-GCK          FGQSAHRAARRRYSRFMDSAQFVGRVGGLAVALGVGAALVTGSGVAWATE
Mvan_5030|M.vanbaalenii_PYR-1       ----------------MKSAQVVGRVGALAVALGVGAAVFTGSGVAWATE
MSMEG_5142|M.smegmatis_MC2_155      ---------------MSQPDRTLGFPDGFVWGTATASYQIEGAVTAGGRA
MAB_3192c|M.abscessus_ATCC_199      ---------------MKWMNAVMASAAVVALGLTACSPRQEAPKEDAGWD
TH_2316|M.thermoresistible__bu      ----------------------VGRVGALAVALGVGVAVATGGTAVAWAD
MUL_3715|M.ulcerans_Agy99           PAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDADDE
                                                                .                     

Mb0912|M.bovis_AF2122/97            TDPSSSSTDSPVDACSPLGG---SASSLA---------------------
Rv0888|M.tuberculosis_H37Rv         TDPSSSSTDSPVDACSPLGG---SASSLA---------------------
MMAR_4644|M.marinum_M               TDSDASNGESWADVPAPPGGENIAASLLPG--------------------
Mflv_1722|M.gilvum_PYR-GCK          DSG--SSASAGAESSTARTSSQDRQAASPSKPARDRAGGRDDAEGGGAE-
Mvan_5030|M.vanbaalenii_PYR-1       DAAGETTAESGATTSEPADDGDAVEPADDGDTVEQVESDDDDEAVGQVEP
MSMEG_5142|M.smegmatis_MC2_155      PSIWDTFSHKPGAVHNGDNG------------------------------
MAB_3192c|M.abscessus_ATCC_199      RGFYWGTATAGYQVEGSAPD------------------------------
TH_2316|M.thermoresistible__bu      SGSTASSSSSQDSSSKSNPAQTRSSAKSGIGSGAGSGPGSRLDRPASRAP
MUL_3715|M.ulcerans_Agy99           SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEA
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4644|M.marinum_M               --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          DRDAQAQDD-ATPETGGETGAPD-DASVDASG-PDTGGTTGDASAEDDDP
Mvan_5030|M.vanbaalenii_PYR-1       EEEAEADEDEAVVEPDEDEVAPDVEEAADADGAPSEDGDGGFQVPAAPRE
MSMEG_5142|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
TH_2316|M.thermoresistible__bu      LGGSGADSSATEQTGAVSSGTSAWRSAGMPAG---------------TSL
MUL_3715|M.ulcerans_Agy99           PQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKS
                                                                                      

Mb0912|M.bovis_AF2122/97            ---------------------------------AIPGASVPQVGVR----
Rv0888|M.tuberculosis_H37Rv         ---------------------------------AIPGASVPQVGVR----
MMAR_4644|M.marinum_M               -------------AAQPGAVPGAALPGTALPGTALPGAASPGMGTP----
Mflv_1722|M.gilvum_PYR-GCK          DEAEERAAWADTGADTDADPDADPDADAS-AATDVATAAVP-SGAGPTAV
Mvan_5030|M.vanbaalenii_PYR-1       DDAPPTEPDEDTGSAAAVASSETGSSEADGVEPAVDTVAVQRLTVEPTAA
MSMEG_5142|M.smegmatis_MC2_155      ---------------------------------DVADDHYHR--------
MAB_3192c|M.abscessus_ATCC_199      --------------------------------------------------
TH_2316|M.thermoresistible__bu      TGRLADSVRDAVKPWRPATTRSTDPTPVETPAEANPEAQPDAHAGSPGES
MUL_3715|M.ulcerans_Agy99           GAGDDGDEGPAPDDPPNTVVHERAPRSGDKSGNSDSGDDSGGNEIKGIDG
                                                                                      

Mb0912|M.bovis_AF2122/97            -----QVDPGSIP-----------DDLLNALIDFLAAVRNGLVPIIENRT
Rv0888|M.tuberculosis_H37Rv         -----QVDPGSIP-----------DDLLNALIDFLAAVRNGLVPIIENRT
MMAR_4644|M.marinum_M               -----QLDPSNIP-----------DDLLNAVINFLASIRNGVVPILENRT
Mflv_1722|M.gilvum_PYR-GCK          VTTEVTVDPPRVPSWRPWPTAFDLRGAVTYVVDLAVSVVDALFHPFAAGP
Mvan_5030|M.vanbaalenii_PYR-1       VSTTVAS-PPEVPSWRPWPTAFDLRSAVTYVVDLATSFVDALLSPFAAGP
MSMEG_5142|M.smegmatis_MC2_155      -----------------------YREDVGLLADLGVTHYR-----FSLAW
MAB_3192c|M.abscessus_ATCC_199      ------------------------SNWRRYVERSAGKPVHPDESNLLADG
TH_2316|M.thermoresistible__bu      TAPETQPAPSSRGIRSMTAVLPDTESTNTESTNTESTVQHDDSERRSSLR
MUL_3715|M.ulcerans_Agy99           STRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTE
                                                                                      

Mb0912|M.bovis_AF2122/97            P--------------------VANPQQVSVPE---------GGTVGPVRF
Rv0888|M.tuberculosis_H37Rv         P--------------------VANPQQVSVPE---------GGTVGPVRF
MMAR_4644|M.marinum_M               P--------------------VATPQQLEIDV---------NGSTGLVPF
Mflv_1722|M.gilvum_PYR-GCK          PPPPGDPSAWGLLAWVRRELFNSTPDEVDNPLPYTQSL-VDGDVVITGNV
Mvan_5030|M.vanbaalenii_PYR-1       PRPPADPSGWALLAWVRREFFNGTPAPVENPLPHTQSLTADGGVVITGNV
MSMEG_5142|M.smegmatis_MC2_155      P-------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199      P-------------------------------------------------
TH_2316|M.thermoresistible__bu      STAASVPELSTPVRLADATAVRALAERLTERRSVTLESVRAFTDVAATTA
MUL_3715|M.ulcerans_Agy99           PPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEA
                                    .                                                 

Mb0912|M.bovis_AF2122/97            DACDPDGNRMTFAVRERGAPGGPQHGIVTVDQRTASFIYTADPGFVGTDT
Rv0888|M.tuberculosis_H37Rv         DACDPDGNRMTFAVRERGAPGGPQHGIVTVDQRTASFIYTADPGFVGTDT
MMAR_4644|M.marinum_M               SAYDPDGNRMTFKVNPRGTPGGPQHGMVNIDESRAAFVYTPEPNFVGIDT
Mflv_1722|M.gilvum_PYR-GCK          GVEDRDGDPLTYEVIGRPRFGG--EVTVDADGNFVYRPMNAMAAVGGTDE
Mvan_5030|M.vanbaalenii_PYR-1       GVVDPDGDALTYSVIGRPHNGG--TVAVDADGNFVYRPMNAMAAVGGTDT
MSMEG_5142|M.smegmatis_MC2_155      -RLQPDG-----------------KGPINTEGLDFYQRLVDELLAHDIQP
MAB_3192c|M.abscessus_ATCC_199      ------------------------VDPYKQADDFRHRYAEDIANAHAMGV
TH_2316|M.thermoresistible__bu      LTSAASVAAATVEPVALITAAPEATPAVDAEQPAAPRLVTGLLAAVGLAP
MUL_3715|M.ulcerans_Agy99           AFVDIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDP
                                                                                      

Mb0912|M.bovis_AF2122/97            FSVNVSDDTS--LHVHGLAGYLG-----------PFHGHDDVATVTVFVG
Rv0888|M.tuberculosis_H37Rv         FSVNVSDDTS--LHVHGLAGYLG-----------PFHGHDDVATVTVFVG
MMAR_4644|M.marinum_M               FTVAVSDDTS--LHVHGLAGYLG-----------PFHGHDDVATVTIFVG
Mflv_1722|M.gilvum_PYR-GCK          FTVAVTDDAAG-LHVHGLLGWLQFVPIL-GSFLNPGGGHGITRTITVTVE
Mvan_5030|M.vanbaalenii_PYR-1       FTVAVSDEHDG-LHVHGLFGWLQFVPIL-GNLLNPGGGHGRTVTIAVTVT
MSMEG_5142|M.smegmatis_MC2_155      WVTLYHWDLP--QTLEDAGGWPAR------------DTAQRFADYAAMTH
MAB_3192c|M.abscessus_ATCC_199      NTFRFGLEWS--RVMPEPGKWDE-------------KELAYYDSVVATLR
TH_2316|M.thermoresistible__bu      FTANSPLAPTQSTPLLALLGWARR---------ETDRAYTQQARSLVTAR
MUL_3715|M.ulcerans_Agy99           VGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQRLKEILREVV
                                                        :                             

Mb0912|M.bovis_AF2122/97            ----------------------------NTPTDTISGDFSMLTYNIAGLP
Rv0888|M.tuberculosis_H37Rv         ----------------------------NTPTDTISGDFSMLTYNIAGLP
MMAR_4644|M.marinum_M               ----------------------------NIPTGTISGDFSMLTYNIAGLP
Mflv_1722|M.gilvum_PYR-GCK          PVDGIDLSLPDGFKWGVAHSGFQAEGGPGSPVDTGSDWYRWVHDPLNRLL
Mvan_5030|M.vanbaalenii_PYR-1       PVDGIDLSLPDDFRWGVAHSGFQAEGGPGSPVDTRSDWYRWVHDPVNRLL
MSMEG_5142|M.smegmatis_MC2_155      ----------------------------GKLHDRIRHWTTLNEPWCSAFL
MAB_3192c|M.abscessus_ATCC_199      -------------------------------ENGMTPMITLMHWVYPGWV
TH_2316|M.thermoresistible__bu      P----------------------AVVSTAAVVDPLPADLIGETERIGRIT
MUL_3715|M.ulcerans_Agy99           PSDAG---------------VIIRTASEGVKEDDIRADVTRLQERWNQIE
                                                                    .                 

Mb0912|M.bovis_AF2122/97            FPLS-----------------------------------SAILPRFFYTK
Rv0888|M.tuberculosis_H37Rv         FPLS-----------------------------------SAILPRFFYTK
MMAR_4644|M.marinum_M               FPLS-----------------------------------SAMLPRFLYTK
Mflv_1722|M.gilvum_PYR-GCK          GLVKGVPENGPGAYVSYEDDARLAREELGVNTFRMGIEWSRIFPDSTASV
Mvan_5030|M.vanbaalenii_PYR-1       GLVKGVPEDGPGAYVSYDGDAALARDELGMNTFRMGIEWSRIFPESTAAV
MSMEG_5142|M.smegmatis_MC2_155      GYAAG-----------------------------------------AHAP
MAB_3192c|M.abscessus_ATCC_199      ADSGG---------------------------------------------
TH_2316|M.thermoresistible__bu      GPGITDGPNRLN--------------------------IYGTDLGIMWDM
MUL_3715|M.ulcerans_Agy99           AKAVEIKQKAAG-----------AAVALYEEPDVLVKVIRDLFNEDFAGL
                                                                                      

Mb0912|M.bovis_AF2122/97            EIGKR--------LNAYYVANVQEDFAYHQFLIKKSKMPSQTP-------
Rv0888|M.tuberculosis_H37Rv         EIGKR--------LNAYYVANVQEDFAYHQFLIKKSKMPSQTP-------
MMAR_4644|M.marinum_M               EIGKR--------LNNFSVSNVQEDFSYHEFLIKKSRMPSQTP-------
Mflv_1722|M.gilvum_PYR-GCK          DISDEGGTVSLADLQALDALANADEVAHYRDVFAALRFHGLDPMVTVNHF
Mvan_5030|M.vanbaalenii_PYR-1       DISDEGGALSLADLEALDELADQDEVAHYRAVFAALRRRGLDPFVTVNHF
MSMEG_5142|M.smegmatis_MC2_155      GRTEP----------AAALAAAHHLMFGHGLAVAAMRAQDGDS-------
MAB_3192c|M.abscessus_ATCC_199      ------------------FMNNLPAFEEFAKAITKRYAGQG---------
TH_2316|M.thermoresistible__bu      GEWRGQRAVHVVFGDTFSGPNMSGDWISNAIMISTSRTLYENPAG-----
MUL_3715|M.ulcerans_Agy99           VVSGDDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHR--
                                                                    .                 

Mb0912|M.bovis_AF2122/97            --------PEPPTLLWPIGVPFSDG----LNTLSEFKVQRLDRQTWYECT
Rv0888|M.tuberculosis_H37Rv         --------PEPPTLLWPIGVPFSDG----LNTLSEFKVQRLDRQTWYECT
MMAR_4644|M.marinum_M               --------PSPPTLLWPIGVPFSDG----LNSLAVFKVKRLDRQTWFQCD
Mflv_1722|M.gilvum_PYR-GCK          TLPVWVHDPVLARPLIQLGLPVAAAGWLSTETAVEFEKYAAYLAWKYGDQ
Mvan_5030|M.vanbaalenii_PYR-1       TLPVWVHDPIVARPLIQLGLPAPAAGWLSSNTAEEFEKYAAYVAWKYGDQ
MSMEG_5142|M.smegmatis_MC2_155      ----------------QLGITVNLT-----PVSPATEEPADVDAARRVDA
MAB_3192c|M.abscessus_ATCC_199      ----------------VLWVSINEP--------LAFGAMEVRTGAIKPDQ
TH_2316|M.thermoresistible__bu      ----FLEQTGPAFQFIPGGQLLSWFFPAEVTVIPTAGVHANGTQYVNYMS
MUL_3715|M.ulcerans_Agy99           -----IDEHLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSGGN
                                                                                      

Mb0912|M.bovis_AF2122/97            SDNCLTLKG----------------------------FTYSQMRLPGGDT
Rv0888|M.tuberculosis_H37Rv         SDNCLTLKG----------------------------FTYSQMRLPGGDT
MMAR_4644|M.marinum_M               ADNCLTPKG----------------------------FSYSQLQLPGGNT
Mflv_1722|M.gilvum_PYR-GCK          VDNWATLNEPFPPVLTEFLAIPWVVP-NWPPGVLRPDLASTFLVNQAIGH
Mvan_5030|M.vanbaalenii_PYR-1       VDNWATLNEPFPPVLTEFLAIPWVVP-NWPPGVLRPDLASTFVVNQAIGH
MSMEG_5142|M.smegmatis_MC2_155      VSNRLFLDA---------------------------LLRGRYPADLSADV
MAB_3192c|M.abscessus_ATCC_199      FNGFLDR------------------------------VADAHRAVYRAAH
TH_2316|M.thermoresistible__bu      VRQWGVPGSWTTN--------------------FSAISRYDQATDTWVTV
MUL_3715|M.ulcerans_Agy99           LEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLT
                                                                                      

Mb0912|M.bovis_AF2122/97            VDVYNLHTNTGGGPTTNANLAQVANYIQQNSAGRAVIVTG-DFNARYSDD
Rv0888|M.tuberculosis_H37Rv         VDVYNLHTNTGGGPTTNANLAQVANYIQQNSAGRAVIVTG-DFNARYSDD
MMAR_4644|M.marinum_M               MDLYNLHANTGGGVLTNANLRQLANYILQNSAGRAVIVTG-DFNALYSED
Mflv_1722|M.gilvum_PYR-GCK          VAAYDAIHAWDTTSAVEGGPAAFVGFTHNMIPARPANPVN-ALDVGAAEA
Mvan_5030|M.vanbaalenii_PYR-1       VAAYDAIHTWDTTAAAADGPAAFVGFTHNMIPARPANPVN-PLDVQAADA
MSMEG_5142|M.smegmatis_MC2_155      AMISDFGFVQPGDEAVIAAPLDFLGVNYYFRETVRFGTGA-PSDNPHARA
MAB_3192c|M.abscessus_ATCC_199      EADPEAKVTTNEAYIPPDVLAQFAGFGVKGIEGSFFDRVAGSLDYLGFDY
TH_2316|M.thermoresistible__bu      PSSVRSAGWLRSSTPYRAGDQNFQQMAYVLQPVDQVGEDGVRYVYAFGTP
MUL_3715|M.ulcerans_Agy99           EALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPHCSGRGILL
                                                          .                           

Mb0912|M.bovis_AF2122/97            QSALLQFAQVNGLTDAWVQVEHGPTTPPFAPTCMVGNECELLDKIFYRSG
Rv0888|M.tuberculosis_H37Rv         QSALLQFAQVNGLTDAWVQVEHGPTTPPFAPTCMVGNECELLDKIFYRSG
MMAR_4644|M.marinum_M               QAGLLDFAGSTGLTDAWVEVEHGPTTPPFAPDCMVGNECELLDKIFYRSG
Mflv_1722|M.gilvum_PYR-GCK          WNHYYNHWFPNAVIDGWIDLDFDGIKSADEIRPDMADKVDFLGVQYYGSQ
Mvan_5030|M.vanbaalenii_PYR-1       WNHFYNKWFPNAVIDGWVDANFDGVKTADEIHPEMAGKVDFLGVQYYGSQ
MSMEG_5142|M.smegmatis_MC2_155      WVG----------STDVEPVRTGLPTTAMGWEIDPTGLYDVLSWVHREYG
MAB_3192c|M.abscessus_ATCC_199      YTG----------TAADNPASAQSMAARWNIKLQPEDIYYVSRHYAQRYP
TH_2316|M.thermoresistible__bu      SGRQGSVHLSRVPEEHITDVSKYEYWDGNAWVSSAAHAAPIIGESTRSAG
MUL_3715|M.ulcerans_Agy99           HADPVDSAPTTGRKADSGGRRNRRSKKNRAEEPSEKEAVAKVPTYAPGEH
                                                                                      

Mb0912|M.bovis_AF2122/97            ----------------QGVTLQAVSYGNEAPKFFN---------------
Rv0888|M.tuberculosis_H37Rv         ----------------QGVTLQAVSYGNEAPKFFN---------------
MMAR_4644|M.marinum_M               ----------------TGVTLQATAYSNEAPNFNN---------------
Mflv_1722|M.gilvum_PYR-GCK          PMVGFGVAPLPGFPFLRGFPIRCSAEETTCSDFNQPIDPGGFREVLEVAA
Mvan_5030|M.vanbaalenii_PYR-1       PMVGFGVAPLPGFPFLRGFPIRCSGEEPTCSDFNQPTDPGGFREVLELAG
MSMEG_5142|M.smegmatis_MC2_155      -----------------PVPIYVTEN------------------------
MAB_3192c|M.abscessus_ATCC_199      -----------------GLPIYIVENG-----------------------
TH_2316|M.thermoresistible__bu      ---------------LFGFIIDWANDPNVFGGYLG---------------
MUL_3715|M.ulcerans_Agy99           PMFKAMAASSSSEAEHGDGEVEESGEELTAAVDDQTAVQVALDLGETEES
                                                        :                             

Mb0912|M.bovis_AF2122/97            SKGEPLSDHSPAVVGFH------YVADNVAVR------------------
Rv0888|M.tuberculosis_H37Rv         SKGEPLSDHSPAVVGFH------YVADNVAVR------------------
MMAR_4644|M.marinum_M               SNGQPLSDHSPPAVAFH------YETTNVSYPN-----------------
Mflv_1722|M.gilvum_PYR-GCK          SYGKPLWVTENGIADAGDAKRPPYLVNHVAVVQDLVAHGLDIRGYT----
Mvan_5030|M.vanbaalenii_PYR-1       SYGKPLWVTENGIADADDSKRPSYIVNHVAVVQDLVAHGADIRGYT----
MSMEG_5142|M.smegmatis_MC2_155      --GAAFDDDAEADGSIRDDDRITFLDSHFRATLRAIDDGADIRGYF----
MAB_3192c|M.abscessus_ATCC_199      ------MVTDNGKPRADGVTRSQYLSDTVFWLQRAKADGIPIVGYN----
TH_2316|M.thermoresistible__bu      ---GLFGAKTGGNVGEMSVQYNEYLGKYVILYGNGRTNNIEMRIADSPEG
MUL_3715|M.ulcerans_Agy99           EETDGTDETDDFDDDSDDSDDSDEDDDTDETNDTDVDADEDEDTDDDSDE
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4644|M.marinum_M               --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          YWSFVDNLEWSEGYDLQFG--LYGSDPDTPELERIPKVASIAALKGITTA
Mvan_5030|M.vanbaalenii_PYR-1       YWSFVDNLEWSEGYELQFG--LYGSDPETPELERIPKPASIAALSGITTA
MSMEG_5142|M.smegmatis_MC2_155      VWSLLDNFEWAYGYAKRFG--LIHVDYAT---QVRTPKASARWFAEVTRR
MAB_3192c|M.abscessus_ATCC_199      YWSLVDNYEWGS-YRPRFG--LYTVDALGDPALKRVPTDAVATYTQITRD
TH_2316|M.thermoresistible__bu      PWSDPIILATPQQYPGLYAPMIHPWSGTGYLLDENGDPDPESLYWNMSMW
MUL_3715|M.ulcerans_Agy99           DEDTEDDDELDDDLDDELDDDDSDSDDEDSESELTEPAAGRPAALEVTTI
                                                                                      

Mb0912|M.bovis_AF2122/97            --------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------
MMAR_4644|M.marinum_M               --------------------------------------
Mflv_1722|M.gilvum_PYR-GCK          NGLPVALLQNYLPG------------------------
Mvan_5030|M.vanbaalenii_PYR-1       NGLPVSLLQTYIPS------------------------
MSMEG_5142|M.smegmatis_MC2_155      NGVPHVFRQNDAPADIR---------------------
MAB_3192c|M.abscessus_ATCC_199      AGTVPGYRPVIPAAKCSTTVGQDSCAPLDPNGPTVALR
TH_2316|M.thermoresistible__bu      GPYNVYLMQTDLSSLVEV--------------------
MUL_3715|M.ulcerans_Agy99           AERPRRRRAAGRPAGPPIHLG-----------------