For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLA EQPAEEGQAEEDQQAPDAVAAEVPDAPGEPAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEP VAGDDADDESGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEAPQKAGGNSTSS DDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKSGAGDDGDEGPAPDDPPNTVVHERAPRSGDKS GNSDSGDDSGGNEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEP PHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWD AAGLGGADRKIEQALKPGDYIVVQVSKDPVGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQR LKEILREVVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEEPDVLVK VIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEHLAKAM DRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFI DMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPHCSGRGILLHADP VDSAPTTGRKADSGGRRNRRSKKNRAEEPSEKEAVAKVPTYAPGEHPMFKAMAASSSSEAEHGDGEVEES GEELTAAVDDQTAVQVALDLGETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDETNDTDVDADEDEDT DDDSDEDEDTEDDDELDDDLDDELDDDDSDSDDEDSESELTEPAAGRPAALEVTTIAERPRRRRAAGRPA GPPIHLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3715 | rne | - | 100% (988) | ribonuclease E Rne |
| M. ulcerans Agy99 | MUL_3341 | sigA | 2e-08 | 38.04% (92) | RNA polymerase sigma factor |
| M. ulcerans Agy99 | MUL_3967 | rho | 2e-07 | 28.89% (135) | transcription termination factor Rho |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2471c | rne | 0.0 | 73.37% (995) | ribonuclease E |
| M. gilvum PYR-GCK | Mflv_2634 | - | 0.0 | 64.84% (1024) | ribonuclease |
| M. tuberculosis H37Rv | Rv2444c | rne | 0.0 | 73.37% (995) | ribonuclease E |
| M. leprae Br4923 | MLBr_01468 | - | 0.0 | 72.28% (992) | putative ribonuclease |
| M. abscessus ATCC 19977 | MAB_1607 | - | 0.0 | 59.98% (1012) | ribonuclease E |
| M. marinum M | MMAR_3768 | rne | 0.0 | 95.48% (1017) | ribonuclease E Rne |
| M. avium 104 | MAV_1728 | - | 0.0 | 75.35% (994) | Rne protein |
| M. smegmatis MC2 155 | MSMEG_4626 | - | 0.0 | 63.70% (1080) | ribonuclease, Rne/Rng family protein |
| M. thermoresistible (build 8) | TH_0997 | rne | 0.0 | 68.45% (786) | POSSIBLE RIBONUCLEASE E RNE |
| M. vanbaalenii PYR-1 | Mvan_3947 | - | 0.0 | 67.11% (982) | ribonuclease |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2634|M.gilvum_PYR-GCK MADNENLQDSNHELGEEPQRLAE---TPSQAKSAPASEKLRVHSLARVLG
Mvan_3947|M.vanbaalenii_PYR-1 MADNENFEAATHDLTDEPQLAAD---SSGSAKDAPAPERLRVHSLARVLG
MSMEG_4626|M.smegmatis_MC2_155 MAEDAHTEDLS---TQTPQQEG-------------LPERLRVHSLARVLG
MUL_3715|M.ulcerans_Agy99 MVDGAPSSDPENEPTQRE----------------DLPDRLRVHSLARTLG
MMAR_3768|M.marinum_M MVDGAPSSDPENEPTQRE----------------DLPDRLRVHSLARTLG
Mb2471c|M.bovis_AF2122/97 MIDGAPPSDPP-EPSQHE----------------ELPDRLRVHSLARTLG
Rv2444c|M.tuberculosis_H37Rv MIDGAPPSDPP-EPSQHE----------------ELPDRLRVHSLARTLG
MLBr_01468|M.leprae_Br4923 MIDGAPPLEPSKEPTQHM----------------ELPDRLRVHSLARTLG
MAV_1728|M.avium_104 MVDGAPTADPSEESTRSG----------------DLPDRLRVHSLARTLG
TH_0997|M.thermoresistible__bu --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997 MADYELPEDLHTSAPEGEHAALTPDTPPAPAEQGELPEKLRVHSLARVLG
Mflv_2634|M.gilvum_PYR-GCK TTSRRIIDALAELDGRARSAHSTVGPDEADRVREVLAAPEPETTP-----
Mvan_3947|M.vanbaalenii_PYR-1 TTSRRIIDALVELDGRTRSAHSTVGREEADRVREVLAEP-----------
MSMEG_4626|M.smegmatis_MC2_155 TTSRRVLDALAEFDGRQRSAHSTVDKADAERVRAALTESPAAETPPEEAP
MUL_3715|M.ulcerans_Agy99 TSSRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLAEQP----------
MMAR_3768|M.marinum_M TSSRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLAEQP----------
Mb2471c|M.bovis_AF2122/97 TTSRRVLDALTALDGRVRSAHSTVDRVDAVRVRDLLATHL----------
Rv2444c|M.tuberculosis_H37Rv TTSRRVLDALTALDGRVRSAHSTVDRVDAVRVRDLLATHL----------
MLBr_01468|M.leprae_Br4923 TTSRRVLDVLSALDGRIRSAHSSVDRVDAVRVRDLLASQP----------
MAV_1728|M.avium_104 TTSKRVLDALSELDGRVRSAHSTVDREDAVRVRDLLAAQP----------
TH_0997|M.thermoresistible__bu --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997 TSTRRVLDALSNLDGRARSPHSNVDKQDAAKVREVLANEA----------
Mflv_2634|M.gilvum_PYR-GCK -------------EQVTEVATDAVEAQAEPQPEAQ-----AQSEAQAQPQ
Mvan_3947|M.vanbaalenii_PYR-1 -----------------EVAT--------PEPDPE-----ASTPEPAAPE
MSMEG_4626|M.smegmatis_MC2_155 AAETPVADLVVVQAEQVEVVTVSEAGPAEPAEPAEPEAPAAEAEAEAETE
MUL_3715|M.ulcerans_Agy99 ----------------------------AEEGQAEEDQQAPDAVAAEVPD
MMAR_3768|M.marinum_M ----------------------------AEEGQAEEGQQAPDAVAAEVPD
Mb2471c|M.bovis_AF2122/97 ----------------------------ETAG-----------VLAASVH
Rv2444c|M.tuberculosis_H37Rv ----------------------------ETAG-----------VLAASVH
MLBr_01468|M.leprae_Br4923 ----------------------------NSPH-----------ELTAVPD
MAV_1728|M.avium_104 ----------------------------SAELEP--------AAEDAASG
TH_0997|M.thermoresistible__bu --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997 ---------------------------EAAPVVAETPAPVAAEEAPAVVT
Mflv_2634|M.gilvum_PYR-GCK PGPEAPAPEAPAE------EEPESRLILETPSAPS----TAEPADYLPLF
Mvan_3947|M.vanbaalenii_PYR-1 LQAPDVDAETVTE------DEPESRLILETPVAP-----VSEPADYLPLF
MSMEG_4626|M.smegmatis_MC2_155 VADEAETPEPTFRGAVLVGDEPESRLILEHANIPPARETQTERPDYLPLF
MUL_3715|M.ulcerans_Agy99 APGE--PAEP------------ESRLMLETQETVQVVETWVERPHYMPLF
MMAR_3768|M.marinum_M APGE--PAEPDEP---------ESRLMLETQETVQVVETWVERPHYMPLF
Mb2471c|M.bovis_AF2122/97 APEA--SEEP------------ESRLMLETQE---TRNADVERPHYMPLF
Rv2444c|M.tuberculosis_H37Rv APEA--SEEP------------ESRLMLETQE---TRNADVERPHYMPLF
MLBr_01468|M.leprae_Br4923 NPVA--LEER------------DSRLVLET---------TVERPHYMPLF
MAV_1728|M.avium_104 GPDAGITGEP------------ESRLLLETPD-------ATERPHYMPLF
TH_0997|M.thermoresistible__bu --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997 GDSADSAEDPDNP--PTTPILIAEATVIEAAAVPVPAAAAPTAYDYGPLF
Mflv_2634|M.gilvum_PYR-GCK VAPQPVRFEDRYEDSDDDDEDASDSDD---SDDSDSDSDDDQSGRPAAKR
Mvan_3947|M.vanbaalenii_PYR-1 VAPQPVRFDEHDHD-DDDGDDVDDDGD---DVDSESDSDEDQPGRPAAKR
MSMEG_4626|M.smegmatis_MC2_155 VAPQPVSFEPAVVDDEDEDDDTETGAESDFDSGADSDSDDDQADRP--RR
MUL_3715|M.ulcerans_Agy99 VAPQPISEPVAGDDADDESGDEGDD-------------DEEQADRPGNRR
MMAR_3768|M.marinum_M VAPQPISEPVAGDDADDESGDEGDD-------------DEEQADRPANRR
Mb2471c|M.bovis_AF2122/97 VAPQPIPEPLADDEDVDDGPDYVADDS--------DADDEGQLDRPANRR
Rv2444c|M.tuberculosis_H37Rv VAPQPIPEPLADDEDVDDGPDYVADDS--------DADDEGQLDRPANRR
MLBr_01468|M.leprae_Br4923 VAPQPI--EVDDDSCADDDVESGDDSD--------VGDDEEQPDRPANRR
MAV_1728|M.avium_104 VAPQPLE-SSDDDGDADETADSDDSD----------GDDDEQADRPSSRR
TH_0997|M.thermoresistible__bu --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997 VAPQAPEPQERPAPVRTEKAEDVDEDAG---ETDDSDADGEGDGDRPARR
Mflv_2634|M.gilvum_PYR-GCK RRRGRRGRGRGRGEQNGDEPSDADGDS--------DGDAETEKARSDDSE
Mvan_3947|M.vanbaalenii_PYR-1 RRRGRRGRGRGRGEQNGDESS-ADSD---------EGDVDTEKAQSGESA
MSMEG_4626|M.smegmatis_MC2_155 RRRGRRGRGRGRGEQNDDATSDADTDS--------TEDQTDGDEQ--ESG
MUL_3715|M.ulcerans_Agy99 RRRGRRGRGRGRGEQGANDGQDQPGDDGDEAPQKAGGNSTSSDDSEAQDG
MMAR_3768|M.marinum_M RRRGRRGRGRGRGEQGANDGQDQPGDDGDEAPQKTGGNSTSSDDTEAQDG
Mb2471c|M.bovis_AF2122/97 RRRGRRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAETDDGDDRDS
Rv2444c|M.tuberculosis_H37Rv RRRGRRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAETDDGDDRDS
MLBr_01468|M.leprae_Br4923 RRRGRRGRGRGRGEQGGSDVQSDDVDG--------AVDSTESEDFDGQDF
MAV_1728|M.avium_104 RRRGRRGRGRGRGEQGGSDGPGDGDNDEPQNRGKKGGQSDGDDDSDGQDA
TH_0997|M.thermoresistible__bu --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997 RRRGRRGRGRGRGEQGGGEGSDDSGDD-AAAEGGEAAEGDDAADGTGDDS
Mflv_2634|M.gilvum_PYR-GCK DDNGEDDNGDDDGAGGDAGTRRRRRRRRRKSGSDDDN---GSGGSPDDPP
Mvan_3947|M.vanbaalenii_PYR-1 DDS-DDDSGEDDGTGADGATRRRRRRRRRKSGSDDD----GENGSPDDPP
MSMEG_4626|M.smegmatis_MC2_155 EDS--DDSGDEDSTTTEGGTRRRRRRRRRKSGSGDS----DDAVSPDDPP
MUL_3715|M.ulcerans_Agy99 ADSEESDNGDDDNGSADGASRRRRRRRRRKSGAGDDGD---EGPAPDDPP
MMAR_3768|M.marinum_M ADSEESDNGDDDNGSADGANRRRRRRRRRKSGAGDDGD---EGPAPDDPP
Mb2471c|M.bovis_AF2122/97 EDTEAGDNGEDENGSLEAGNRRRRRRRRRKSASGDDNDAALEGPLPDDPP
Rv2444c|M.tuberculosis_H37Rv EDTEAGDNGEDENGSLEAGNRRRRRRRRRKSASGDDNDAALEGPLPDDPP
MLBr_01468|M.leprae_Br4923 DESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGED-----EGCAPDDPP
MAV_1728|M.avium_104 EDADDSDTGDD--GSADGGNRRRRRRRRRKSGSGDDNE---DGPSPDDPP
TH_0997|M.thermoresistible__bu -------------------------------------------VSPDDPP
MAB_1607|M.abscessus_ATCC_1997 PAPDGDESNAEDGDTPEGASRRRRRRRRRKAGSGDDG----DGPSDDDPP
****
Mflv_2634|M.gilvum_PYR-GCK NTVVHEREPRKSG-RADKGDK-----SDEIQGISGSTRLEAKRQRRRDGR
Mvan_3947|M.vanbaalenii_PYR-1 NTVVHEREPRKSANRGDKTSS-----DSEIQGISGSTRLEAKRQRRRDGR
MSMEG_4626|M.smegmatis_MC2_155 NTVVHERAPRTER--SDKSD------DSEIQGISGSTRLEAKRQRRRDGR
MUL_3715|M.ulcerans_Agy99 NTVVHERAPRSGDKSGNSDSG-DDSGGNEIKGIDGSTRLEAKRQRRRDGR
MMAR_3768|M.marinum_M NTVVHERAPRSGGKSGNSDSG-DDSGGNEIKGIDGSTRLEAKRQRRRDGR
Mb2471c|M.bovis_AF2122/97 NTVVHERVPRAGDKAGNSQD--GGSGSTEIKGIDGSTRLEAKRQRRRDGR
Rv2444c|M.tuberculosis_H37Rv NTVVHERVPRAGDKAGNSQD--GGSGSTEIKGIDGSTRLEAKRQRRRDGR
MLBr_01468|M.leprae_Br4923 NTVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGR
MAV_1728|M.avium_104 NTVVHERPPRNGKNGG--DDG-NGSSSSEIKGIDGSTRLEAKRQRRRDGR
TH_0997|M.thermoresistible__bu NTVVHERVPRTEKEER-------DQAHSEIQGITGSTRLEAKRQRRRDGR
MAB_1607|M.abscessus_ATCC_1997 NTVVHERKPRAER-------------GDEIQGISGSTRLEAKRQRRRDGR
******* ** :*:** ****************
Mflv_2634|M.gilvum_PYR-GCK DAGRRRPPILSEAEFLARREAVERTMVVRDKVRTEPPHEGARYTQIAVLE
Mvan_3947|M.vanbaalenii_PYR-1 DAGRRRPPILSEAEFLARREAVERMMVIRDKVRTEPPHEGARYTQIAVLE
MSMEG_4626|M.smegmatis_MC2_155 DAGRRRPPILSEAEFLARREAVERTMIVRDKVRTEPPHEGARYTQIAVLE
MUL_3715|M.ulcerans_Agy99 DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPHPGSRYTQIAVLE
MMAR_3768|M.marinum_M DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPHPGSRYTQIAVLE
Mb2471c|M.bovis_AF2122/97 DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPLPGTRYTQIAVLE
Rv2444c|M.tuberculosis_H37Rv DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPLPGTRYTQIAVLE
MLBr_01468|M.leprae_Br4923 DAGRRRSSVLSEAEFLARRESVERVMVVRDRIRTEPPHPGARYTQIAVLE
MAV_1728|M.avium_104 DAGRRRPPVLTEAEFLARREAVERVMVVRDRIRTEPPHQGSRYTQIAVLE
TH_0997|M.thermoresistible__bu DAGRRRPPILSEAEFLARREAVERVMVVRDKVRTEPPHQGARYTQIAVLE
MAB_1607|M.abscessus_ATCC_1997 DAGRRRPPILTEAEFLARREAVDRVMVVRDKTRSEPPHEGARYTQIAVLE
******..:*:*********:*:* *::**: *:*** *:*********
Mflv_2634|M.gilvum_PYR-GCK DGVVVEHFVTSAAQVSLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
Mvan_3947|M.vanbaalenii_PYR-1 DGVVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MSMEG_4626|M.smegmatis_MC2_155 DGVVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MUL_3715|M.ulcerans_Agy99 DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MMAR_3768|M.marinum_M DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
Mb2471c|M.bovis_AF2122/97 DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
Rv2444c|M.tuberculosis_H37Rv DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MLBr_01468|M.leprae_Br4923 DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MAV_1728|M.avium_104 DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
TH_0997|M.thermoresistible__bu DGVVVEHFVTSSASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MAB_1607|M.abscessus_ATCC_1997 DGVLVEHFVTSAASASLVGNIYLGVVQNVLPSMEAAFVDIGRGRNGVLYA
**::*******:*..*********:*************************
Mflv_2634|M.gilvum_PYR-GCK GEVNWEAAGLGGAQRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
Mvan_3947|M.vanbaalenii_PYR-1 GEVNWEAAGLGGAQRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
MSMEG_4626|M.smegmatis_MC2_155 GEVNWEAAGLGGQNRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
MUL_3715|M.ulcerans_Agy99 GEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGHKGARLTTQVSLA
MMAR_3768|M.marinum_M GEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGHKGARLTTQVSLA
Mb2471c|M.bovis_AF2122/97 GEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
Rv2444c|M.tuberculosis_H37Rv GEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
MLBr_01468|M.leprae_Br4923 GEVNWEAAGLGGADRKIEQALKPGDYIVVQVNKDPVGHKGARLTTQVSLA
MAV_1728|M.avium_104 GEVNWEAAGLGGSDRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
TH_0997|M.thermoresistible__bu GEVNWEAAGLGGQNRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQLSLA
MAB_1607|M.abscessus_ATCC_1997 GEVNWDAAGLGGSNRKIEQALKSGDYVLVQVSKDPVGHKGARLTTQISLA
*****:****** :********.***::***.**************:***
Mflv_2634|M.gilvum_PYR-GCK GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSNAGVIIRTASEGV
Mvan_3947|M.vanbaalenii_PYR-1 GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MSMEG_4626|M.smegmatis_MC2_155 GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MUL_3715|M.ulcerans_Agy99 GRYLVYVAGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MMAR_3768|M.marinum_M GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
Mb2471c|M.bovis_AF2122/97 GRFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
Rv2444c|M.tuberculosis_H37Rv GRFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MLBr_01468|M.leprae_Br4923 GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGVIIRTASEGV
MAV_1728|M.avium_104 GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
TH_0997|M.thermoresistible__bu GRYLVYVPGATSTGISRKLPDTERQRLKEILREVVPPDAGVIIRTASEGV
MAB_1607|M.abscessus_ATCC_1997 GRYLVYVPGASSTGISRKLPDTERQRLKEILRDIVPADAGVIIRTASEGV
**:****.**:*********************::**.:************
Mflv_2634|M.gilvum_PYR-GCK KEDDIRTDVERLQKRWTDIEAKAAEVTAKKAGAAVALYEEPDVLVKVIRD
Mvan_3947|M.vanbaalenii_PYR-1 KEEDIRSDVERLQKRWTEIEAKAAEITEKKAGAAVALYEEPDVLVKVIRD
MSMEG_4626|M.smegmatis_MC2_155 KEEDIRSDVERLQKRWSEIEAKAAEVTEKKAGAAVALYEEPDVLVKVIRD
MUL_3715|M.ulcerans_Agy99 KEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEEPDVLVKVIRD
MMAR_3768|M.marinum_M KEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEEPDVLVKVIRD
Mb2471c|M.bovis_AF2122/97 KEDDIRADVARLRERWEQIEAKAQETKEKAAGAAVALYEEPDVLVKVIRD
Rv2444c|M.tuberculosis_H37Rv KEDDIRADVARLRERWEQIEAKAQETKEKAAGAAVALYEEPDVLVKVIRD
MLBr_01468|M.leprae_Br4923 KEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRD
MAV_1728|M.avium_104 KEDDIRGDVTRLQERWKQIEAKAIEIKEKAAGAAVALYEEPDVLVKVIRD
TH_0997|M.thermoresistible__bu KEEDIRADVNRLQERWTQIEAKAAELTEKKAGQAVALYEEPDVLVKVIRD
MAB_1607|M.abscessus_ATCC_1997 REEDIRADVQRLQEQWQGIEQSATDLTSKASGAAVALYEEPDVLVKVVRD
:*:*** ** **:::* ** .: : . * :* **************:**
Mflv_2634|M.gilvum_PYR-GCK LFNEDFSNLIVSGDQAWKTIDDYVTAVAPELLPRITRYEPAGSPEAGTAP
Mvan_3947|M.vanbaalenii_PYR-1 LFNEDFTGLTVSGDHAWKTINDYVTAVAPELLPRMTQYEPASP----DAP
MSMEG_4626|M.smegmatis_MC2_155 LFNEDFSSLIVSGDEAWNTINSYVEAVAPDLMPRLTKYEPAGP----DAP
MUL_3715|M.ulcerans_Agy99 LFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGP
MMAR_3768|M.marinum_M LFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGP
Mb2471c|M.bovis_AF2122/97 LFNEDFVGLIVSGDEAWNTINEYVNSVAPELVSKLTKYESADGPDGQSAP
Rv2444c|M.tuberculosis_H37Rv LFNEDFVGLIVSGDEAWNTINEYVNSVAPELVSKLTKYESADGPDGQSAP
MLBr_01468|M.leprae_Br4923 LFNDDFSGLVVSGDEAWNTINEYVNSVAPELVSKLTKYDPPIGPDGQHGP
MAV_1728|M.avium_104 LFNEDFAGLIVSGDDAWNTINEYVNSVAPDLVSKVTKYEPATGPDGTPGP
TH_0997|M.thermoresistible__bu LFNEDFSRLIVSGDHAWNTINEYVSTVAPDLMPRLTKYEPAS----EDGP
MAB_1607|M.abscessus_ATCC_1997 LFNEDFSKLIIEGDAAWDTIDDYVKTVAPDLLSRIERYESGE------GP
***:** * :.** **.**:.** :***:*:.:: :*:. .*
Mflv_2634|M.gilvum_PYR-GCK DVFAVHRIDEQLAKAMDRKVYLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
Mvan_3947|M.vanbaalenii_PYR-1 DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
MSMEG_4626|M.smegmatis_MC2_155 DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
MUL_3715|M.ulcerans_Agy99 DVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
MMAR_3768|M.marinum_M DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
Mb2471c|M.bovis_AF2122/97 DVFTVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGAG
Rv2444c|M.tuberculosis_H37Rv DVFTVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGAG
MLBr_01468|M.leprae_Br4923 DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSG
MAV_1728|M.avium_104 DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSG
TH_0997|M.thermoresistible__bu DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSG
MAB_1607|M.abscessus_ATCC_1997 DVFAVHRIDEQLAKALDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGAG
***:******:****:****:*****************:*********:*
Mflv_2634|M.gilvum_PYR-GCK GNLEQTVTRNNLEAAEETVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
Mvan_3947|M.vanbaalenii_PYR-1 GNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MSMEG_4626|M.smegmatis_MC2_155 GNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MUL_3715|M.ulcerans_Agy99 GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MMAR_3768|M.marinum_M GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
Mb2471c|M.bovis_AF2122/97 GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
Rv2444c|M.tuberculosis_H37Rv GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MLBr_01468|M.leprae_Br4923 GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MAV_1728|M.avium_104 GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
TH_0997|M.thermoresistible__bu GNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MAB_1607|M.abscessus_ATCC_1997 GNLEETVTRNNLEAAEEIVRQLRLRDVGGIVVIDFIDMVLESNRDLVLRR
****:***:******** ********:***********************
Mflv_2634|M.gilvum_PYR-GCK LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTTCTHCSGRGI
Mvan_3947|M.vanbaalenii_PYR-1 LTEALARDRTRHQVSEVTSLGLVQLTRKKLGTGLIEAFSTTCSHCAGRGI
MSMEG_4626|M.smegmatis_MC2_155 LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTACTHCGGRGI
MUL_3715|M.ulcerans_Agy99 LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPHCSGRGI
MMAR_3768|M.marinum_M LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPHCSGRGI
Mb2471c|M.bovis_AF2122/97 LTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPNCSGRGI
Rv2444c|M.tuberculosis_H37Rv LTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPNCSGRGI
MLBr_01468|M.leprae_Br4923 LTEVLARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPNCTGRGI
MAV_1728|M.avium_104 LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPNCGGRGI
TH_0997|M.thermoresistible__bu LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLLEAFSTTCTHCNGRGI
MAB_1607|M.abscessus_ATCC_1997 LTEALGRDRTRHQVSEVTSLGLVQLTRKKLGTGLIEAFSSTCTHCAGRGI
*** *.**********************:*****:****::*.:* ****
Mflv_2634|M.gilvum_PYR-GCK MLHGDPVDSS--SGSNGRKADSGGGGNGGGGGGGGRRSRRGKRGAKPEP-
Mvan_3947|M.vanbaalenii_PYR-1 MLHGDPVDSM--APANGRKSEPG----------TGRRSKRGKRGARAEQ-
MSMEG_4626|M.smegmatis_MC2_155 VLHGDPIDSA--SSNGGRKSDSSG----GGGSGGGRRGKRGKKGAARTE-
MUL_3715|M.ulcerans_Agy99 LLHADPVDS---APTTGRKADSG-----------GRRNRRSKKNRAEEPS
MMAR_3768|M.marinum_M LLHADPVDS---APTTGRKADSG-----------GRRNRRSKKNRAEEPS
Mb2471c|M.bovis_AF2122/97 LLHADPVDS---AAATGRKSEPG-----------ARRGKRSKKSRSEESS
Rv2444c|M.tuberculosis_H37Rv LLHADPVDS---AAATGRKSEPG-----------ARRGKRSKKSRSEESS
MLBr_01468|M.leprae_Br4923 LLHTDPANS---TPMVGRKSESG-----------GRRSKRSKKNRSDE--
MAV_1728|M.avium_104 LLHADPVDS---APSNGRKSESG-----------GRRGRR-KKSKAEEP-
TH_0997|M.thermoresistible__bu VLHTDPVDS---AQPS-RRSDSG-----------SRRSKRSKRSRSDD--
MAB_1607|M.abscessus_ATCC_1997 VLHVDPVDNASNASSPAKKAETG------------RRAKRSRKGKTDD--
:** ** :. : ::::.. ** :* ::.
Mflv_2634|M.gilvum_PYR-GCK -EVQVTKVPAHLPGEHPMFKAMAAANGKDE------DGEDGQDGEERDDV
Mvan_3947|M.vanbaalenii_PYR-1 -EVPVVKVPSHSPGEHPMFKAMAAANGKHE------DDDS---EHEDDGT
MSMEG_4626|M.smegmatis_MC2_155 -EVHVAKVPDHTPGEHPMFKAMAAANGKHEGDEDHEDHEDHETAEDTTAA
MUL_3715|M.ulcerans_Agy99 EKEAVAKVPTYAPGEHPMFKAMAASSS-----SEAEHGDGE---VEESGE
MMAR_3768|M.marinum_M EKEAVAKVPTHAPGEHPMFKAMAASSS-----SEAEHGDGE---VEESGE
Mb2471c|M.bovis_AF2122/97 DRSMVAKVPVHAPGEHPMFKAMAAGLS-----SLAGRGDEE---SGEPAA
Rv2444c|M.tuberculosis_H37Rv DRSMVAKVPVHAPGEHPMFKAMAAGLS-----SLAGRGDEE---SGEPAA
MLBr_01468|M.leprae_Br4923 --TAVVKVPVHAPGEHPMFKAMAAGSS-----SVVVGGEDE---SNESGT
MAV_1728|M.avium_104 ---VVAKVPVHSPGEHPMFKAMAAGSS-----TQAASDEDESA-AEEAGD
TH_0997|M.thermoresistible__bu --VQVVKVPPHPPGEHPLFKAMAAASERAD--SEAKDDTEETGDGGKDAA
MAB_1607|M.abscessus_ATCC_1997 --VVVARTPSHPQGEHPMFKAMAAANG-----------------------
*.:.* : ****:******.
Mflv_2634|M.gilvum_PYR-GCK SLAPEEVAEIDADATPTVADTDD---------------------------
Mvan_3947|M.vanbaalenii_PYR-1 AVPPEEVAELDADATRAVTDSD----------------------------
MSMEG_4626|M.smegmatis_MC2_155 EVRDDTRDEHDADERAHVVTAAVG--------------------------
MUL_3715|M.ulcerans_Agy99 ELTAAVDDQTAVQVALDLG-------------------------------
MMAR_3768|M.marinum_M ELTAAVDDQTAVQVALDLGQTD----------------------------
Mb2471c|M.bovis_AF2122/97 ELA----EQAGDQPPTDLD-------------------------------
Rv2444c|M.tuberculosis_H37Rv ELA----EQAGDQPPTDLD-------------------------------
MLBr_01468|M.leprae_Br4923 ELTGKIDEPLEEQAVAGLD-------------------------------
MAV_1728|M.avium_104 ELERKKAARAEELEAAEDT-------------------------------
TH_0997|M.thermoresistible__bu KVAAKVKEKVAAEDRAKVGAQDGVEEATPDGVETEAAAATRAERVRTAVS
MAB_1607|M.abscessus_ATCC_1997 --------HHEDDEDADVN-------------------------------
Mflv_2634|M.gilvum_PYR-GCK ------------------EFGDDSEDDDSEDDD-----------SEDDDS
Mvan_3947|M.vanbaalenii_PYR-1 ---------------------DDDLDDDFDDED-----------ADDEDT
MSMEG_4626|M.smegmatis_MC2_155 ------------------AAGDEDLDDSDEDSD-----------LDSDEE
MUL_3715|M.ulcerans_Agy99 -----------------ETEESEETDGTDETD------------DFDDDS
MMAR_3768|M.marinum_M -----------------ETEETDETDETDETD------------DFDDDS
Mb2471c|M.bovis_AF2122/97 ------------------DTAQADFEDTEDTD------------EDEDE-
Rv2444c|M.tuberculosis_H37Rv ------------------DTAQADFEDTEDTD------------EDEDE-
MLBr_01468|M.leprae_Br4923 ------------------DVDQEDFDTDEEDD------------LDDDEE
MAV_1728|M.avium_104 -------------------EDLEDTEDDDEDS------------DDSDDS
TH_0997|M.thermoresistible__bu GDAQASAGDLDDEDLANGDLEDEYLDDEDEDEDLEDGDLENGDLDDEDDD
MAB_1607|M.abscessus_ATCC_1997 ---------------------EDALDDDALEEV-----------EEVEEI
: . ::
Mflv_2634|M.gilvum_PYR-GCK EDDDSDVDEIDLDDDDEDEDDDIDELDDDEDSDDED--------------
Mvan_3947|M.vanbaalenii_PYR-1 DDED----EIDLDDDDDEADDDIEELDD-EDSDDEE--------------
MSMEG_4626|M.smegmatis_MC2_155 SDDESDEDEIELDDDEDELDEDIEVIGDSDDSDDSDDS------------
MUL_3715|M.ulcerans_Agy99 DDSDDSDEDDDTDETNDTDVDADEDEDTDDDSDED--------EDTEDD-
MMAR_3768|M.marinum_M DDSDDSDEDDDSDETNDTDVDAGEDEDTDDDSDEDSDDDSDEDEDTEDDE
Mb2471c|M.bovis_AF2122/97 LDADEDLEDLDDE-DLDEDLDVEDSDSDDEDSDED---------------
Rv2444c|M.tuberculosis_H37Rv LDADEDLEDLDDE-DLDEDLDVEDSDSDDEDSDED---------------
MLBr_01468|M.leprae_Br4923 LDDEEDLGDDDEELDLDDDLDVDE---DESDSEAD---------------
MAV_1728|M.avium_104 DDEDLDDEDIDDEEDLGDDDEDLELDDDDLDTEDS---------------
TH_0997|M.thermoresistible__bu EDLEDGEIDVDLDEDLDDDIEVLNGDPDDEEADEDVDS------------
MAB_1607|M.abscessus_ATCC_1997 VETIQSAETPDNVPDQDEPEHEPASAGSNAASEPWA--------------
: : . ::
Mflv_2634|M.gilvum_PYR-GCK -------------------------EDDDEDDDSDFDDDDEDEDSDEDDE
Mvan_3947|M.vanbaalenii_PYR-1 -------------------------TDEDSDD-----EDTDGEDSDEEEE
MSMEG_4626|M.smegmatis_MC2_155 ------------------------DEDDDSDDSDDDSDEDEDSDSDEDEE
MUL_3715|M.ulcerans_Agy99 --------------DELDDDLDDELDDDDSDSD-DEDSESELTEPAAGRP
MMAR_3768|M.marinum_M LDDDLDEDDLDDDLDEDDDDLDDELDDDDSDSD-DEDGESELTEPAAGRP
Mb2471c|M.bovis_AF2122/97 --------------------------AADADVD-EED--AAGLDGSPGEV
Rv2444c|M.tuberculosis_H37Rv --------------------------AADADVD-EED--AAGLDGSPGEV
MLBr_01468|M.leprae_Br4923 --------------------------LDSADVL-DRS--TLLIRNRSG--
MAV_1728|M.avium_104 --------------------------DDSDDSD-DSEDSDDSEDQRDPAA
TH_0997|M.thermoresistible__bu ---------------------YEDPYDADADADSDSDADADDEDSGDDRA
MAB_1607|M.abscessus_ATCC_1997 --------------------------EGAPEAAATEPGTAEPEAPAATPE
:
Mflv_2634|M.gilvum_PYR-GCK EE-----PVAAAPVGRHRRRAAARPAGPPIRD-
Mvan_3947|M.vanbaalenii_PYR-1 PV-----AVAVRP-GRQRRRAAARPAGPPSQD-
MSMEG_4626|M.smegmatis_MC2_155 PVREVYEPPVTAPRARVRRRAAARPAGPPSHD-
MUL_3715|M.ulcerans_Agy99 AAL----EVTTIAERPRRRRAAGRPAGPPIHLG
MMAR_3768|M.marinum_M AAL----EVTTIAERPRRRRAAGRPAGPPIHLG
Mb2471c|M.bovis_AF2122/97 DVP----GVTELAPTRPRRRVAGRPAGPPIRLD
Rv2444c|M.tuberculosis_H37Rv DVP----GVTELAPTRPRRRVAGRPAGPPIRLD
MLBr_01468|M.leprae_Br4923 -----------FARPR-RRRAAGRPAGPPIHVD
MAV_1728|M.avium_104 ECP----GVSALGRPR-RRRAAGRPAGPPIHAD
TH_0997|M.thermoresistible__bu AGR----YAAPTVTRRPRRRAAVRPAGPPVQS-
MAB_1607|M.abscessus_ATCC_1997 P-------AAAAPTRPRRRRSAARAAGPPVEH-
*** * *.**** .