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SQPDRTLGFPDGFVWGTATASYQIEGAVTAGGRAPSIWDTFSHKPGAVHNGDNGDVADDHYHRYREDVGL LADLGVTHYRFSLAWPRLQPDGKGPINTEGLDFYQRLVDELLAHDIQPWVTLYHWDLPQTLEDAGGWPAR DTAQRFADYAAMTHGKLHDRIRHWTTLNEPWCSAFLGYAAGAHAPGRTEPAAALAAAHHLMFGHGLAVAA MRAQDGDSQLGITVNLTPVSPATEEPADVDAARRVDAVSNRLFLDALLRGRYPADLSADVAMISDFGFVQ PGDEAVIAAPLDFLGVNYYFRETVRFGTGAPSDNPHARAWVGSTDVEPVRTGLPTTAMGWEIDPTGLYDV LSWVHREYGPVPIYVTENGAAFDDDAEADGSIRDDDRITFLDSHFRATLRAIDDGADIRGYFVWSLLDNF EWAYGYAKRFGLIHVDYATQVRTPKASARWFAEVTRRNGVPHVFRQNDAPADIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5142 | - | - | 100% (475) | beta-glucosidase A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1722 | - | 1e-40 | 30.02% (533) | glycoside hydrolase family protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3192c | - | 1e-32 | 27.16% (486) | putative glycosyl hydrolase (beta-glucosidase) |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5030 | - | 1e-38 | 29.73% (528) | glycoside hydrolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1722|M.gilvum_PYR-GCK MGGGTWRSQSTDRHLASDAVGRGAVRQVCRVGADGVRQNDGFGQSAHRAA
Mvan_5030|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK RRRYSRFMDSAQFVGRVGGLAVALGVGAALVTGSGVAWATEDSG--SSAS
Mvan_5030|M.vanbaalenii_PYR-1 -------MKSAQVVGRVGALAVALGVGAAVFTGSGVAWATEDAAGETTAE
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK AGAESSTARTSSQDRQAASPSKPARDRAGGRDDAEGGGAE-DRDAQAQDD
Mvan_5030|M.vanbaalenii_PYR-1 SGATTSEPADDGDAVEPADDGDTVEQVESDDDDEAVGQVEPEEEAEADED
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK -ATPETGGETGAPD-DASVDASG-PDTGGTTGDASAEDDDPDEAEERAAW
Mvan_5030|M.vanbaalenii_PYR-1 EAVVEPDEDEVAPDVEEAADADGAPSEDGDGGFQVPAAPREDDAPPTEPD
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK ADTGADTDADPDADPDADAS-AATDVATAAVP-SGAGPTAVVTTEVTVDP
Mvan_5030|M.vanbaalenii_PYR-1 EDTGSAAAVASSETGSSEADGVEPAVDTVAVQRLTVEPTAAVSTTVAS-P
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK PRVPSWRPWPTAFDLRGAVTYVVDLAVSVVDALFHPFAAGPPPPPGDPSA
Mvan_5030|M.vanbaalenii_PYR-1 PEVPSWRPWPTAFDLRSAVTYVVDLATSFVDALLSPFAAGPPRPPADPSG
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK WGLLAWVRRELFNSTPDEVDNPLPYTQSL-VDGDVVITGNVGVEDRDGDP
Mvan_5030|M.vanbaalenii_PYR-1 WALLAWVRREFFNGTPAPVENPLPHTQSLTADGGVVITGNVGVVDPDGDA
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK LTYEVIGRPRFGGEVTVDADGNFVYRPMNAMAAVGGTDEFTVAVTDDAAG
Mvan_5030|M.vanbaalenii_PYR-1 LTYSVIGRPHNGGTVAVDADGNFVYRPMNAMAAVGGTDTFTVAVSDEHDG
MSMEG_5142|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3192c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1722|M.gilvum_PYR-GCK LHVHGLLGWLQFVPILGSFLNPGGGHGITRTITVTVEPVDGIDLSLPDGF
Mvan_5030|M.vanbaalenii_PYR-1 LHVHGLFGWLQFVPILGNLLNPGGGHGRTVTIAVTVTPVDGIDLSLPDDF
MSMEG_5142|M.smegmatis_MC2_155 ------------------------------------MSQPDRTLGFPDGF
MAB_3192c|M.abscessus_ATCC_199 ------------MKWMNAVMASAAVVALGLTACSPRQEAPKEDAGWDRGF
. .*
Mflv_1722|M.gilvum_PYR-GCK KWGVAHSGFQAEGGPGSP---VDTGSDWYRWVHDPLNRLLGLVKGVPENG
Mvan_5030|M.vanbaalenii_PYR-1 RWGVAHSGFQAEGGPGSP---VDTRSDWYRWVHDPVNRLLGLVKGVPEDG
MSMEG_5142|M.smegmatis_MC2_155 VWGTATASYQIEGAVTAG---GRAPSIWDTFSHKPGAVHNGDNGDVADD-
MAB_3192c|M.abscessus_ATCC_199 YWGTATAGYQVEGSAPDSNWRRYVERSAGKPVHPDESNLLADGPVDPYKQ
**.* :.:* **. . * . . .
Mflv_1722|M.gilvum_PYR-GCK PGAYVSYEDDARLAREELGVNTFRMGIEWSRIFPDSTASVDISDEGGTVS
Mvan_5030|M.vanbaalenii_PYR-1 PGAYVSYDGDAALARDELGMNTFRMGIEWSRIFPESTAAVDISDEGGALS
MSMEG_5142|M.smegmatis_MC2_155 --HYHRYREDVGLL-ADLGVTHYRFSLAWPRLQPDGKGPINTEG------
MAB_3192c|M.abscessus_ATCC_199 ADDFRHRYAEDIANAHAMGVNTFRFGLEWSRVMPEPGKWDEKE-------
: : :*:. :*:.: *.*: *: : .
Mflv_1722|M.gilvum_PYR-GCK LADLQALDALANADEVAHYRDVFAALRFHGLDPMVTVNHFTLPVWVHDPV
Mvan_5030|M.vanbaalenii_PYR-1 LADLEALDELADQDEVAHYRAVFAALRRRGLDPFVTVNHFTLPVWVHDPI
MSMEG_5142|M.smegmatis_MC2_155 ---------------LDFYQRLVDELLAHDIQPWVTLYHWDLPQTLED--
MAB_3192c|M.abscessus_ATCC_199 ---------------LAYYDSVVATLRENGMTPMITLMHWVYPGWVAD--
: .* :. * ..: * :*: *: * : *
Mflv_1722|M.gilvum_PYR-GCK LARPLIQLGLPVAAAGWLSTETAVEFEKYAAYLAWKYGDQVDNWATLNEP
Mvan_5030|M.vanbaalenii_PYR-1 VARPLIQLGLPAPAAGWLSSNTAEEFEKYAAYVAWKYGDQVDNWATLNEP
MSMEG_5142|M.smegmatis_MC2_155 -------------AGGWPARDTAQRFADYAAMTHGKLHDRIRHWTTLNEP
MAB_3192c|M.abscessus_ATCC_199 -------------SGGFMN--NLPAFEEFAKAITKRYAGQGVLWVSINEP
:.*: . * .:* : .: *.::***
Mflv_1722|M.gilvum_PYR-GCK FPPVLTEFLAIPWVVPNWPPGVLRPDLASTFLVNQAIGHVAAYDAIHAWD
Mvan_5030|M.vanbaalenii_PYR-1 FPPVLTEFLAIPWVVPNWPPGVLRPDLASTFVVNQAIGHVAAYDAIHTWD
MSMEG_5142|M.smegmatis_MC2_155 WCSAFLGYAAG-----AHAPGRTEPAAALAAAHHLMFGHGLAVAAMRAQD
MAB_3192c|M.abscessus_ATCC_199 LAFGAMEVRTG----------AIKPDQFNGFLDRVADAHRAVYRAAHEAD
: .* . .* . * : *
Mflv_1722|M.gilvum_PYR-GCK TTSAVEGGPAAFVGFTHNMIPARPANPVNALDVGAAEAWNHYYNHWFPNA
Mvan_5030|M.vanbaalenii_PYR-1 TTAAAADGPAAFVGFTHNMIPARPANPVNPLDVQAADAWNHFYNKWFPNA
MSMEG_5142|M.smegmatis_MC2_155 GDSQLG--------ITVNLTPVSPAT-EEPADVDAARRVDAVSNRLFLDA
MAB_3192c|M.abscessus_ATCC_199 PEAKVT----------TNEAYIPPDVLAQFAGFGVKGIEGSFFDR-----
: * * : .. . . ::
Mflv_1722|M.gilvum_PYR-GCK VIDGWIDLDFDG----IKSADEIRP----DMADKVDFLGVQYYGSQPMVG
Mvan_5030|M.vanbaalenii_PYR-1 VIDGWVDANFDG----VKTADEIHP----EMAGKVDFLGVQYYGSQPMVG
MSMEG_5142|M.smegmatis_MC2_155 LLRGRYPADLSADVAMISDFGFVQPGDEAVIAAPLDFLGVNYYFRETVR-
MAB_3192c|M.abscessus_ATCC_199 ------------------------------VAGSLDYLGFDYY-------
:* :*:**.:**
Mflv_1722|M.gilvum_PYR-GCK FGVAPLPGFPFLRGFPIRCSAEET----TCSDFNQPIDPGGFREVLEVAA
Mvan_5030|M.vanbaalenii_PYR-1 FGVAPLPGFPFLRGFPIRCSGEEP----TCSDFNQPTDPGGFREVLELAG
MSMEG_5142|M.smegmatis_MC2_155 FGTGAPSDNPHARAWVGSTDVEPVRTGLPTTAMGWEIDPTGLYDVLSWVH
MAB_3192c|M.abscessus_ATCC_199 --TGTAADNPASAQS-------------MAARWNIKLQPEDIYYVSRHYA
... .. * : . :* .: *
Mflv_1722|M.gilvum_PYR-GCK SYG--KPLWVTENGIADAGDAKRP---------PYLVNHVAVVQDLVAHG
Mvan_5030|M.vanbaalenii_PYR-1 SYG--KPLWVTENGIADADDSKRP---------SYIVNHVAVVQDLVAHG
MSMEG_5142|M.smegmatis_MC2_155 REYGPVPIYVTENGAAFDDDAEADGSIRDDDRITFLDSHFRATLRAIDDG
MAB_3192c|M.abscessus_ATCC_199 QRYPGLPIYIVENGMVTDNGKPRADG---VTRSQYLSDTVFWLQRAKADG
*:::.*** . .. :: . . .*
Mflv_1722|M.gilvum_PYR-GCK LDIRGYTYWSFVDNLEWSEGYDLQFGLYGSDPDTPELERIPKVASIAALK
Mvan_5030|M.vanbaalenii_PYR-1 ADIRGYTYWSFVDNLEWSEGYELQFGLYGSDPETPELERIPKPASIAALS
MSMEG_5142|M.smegmatis_MC2_155 ADIRGYFVWSLLDNFEWAYGYAKRFGLIHVDYAT---QVRTPKASARWFA
MAB_3192c|M.abscessus_ATCC_199 IPIVGYNYWSLVDNYEWGS-YRPRFGLYTVDALGDPALKRVPTDAVATYT
* ** **::** **. * :*** * :
Mflv_1722|M.gilvum_PYR-GCK GITTANGLPVALLQNYLPG------------------------
Mvan_5030|M.vanbaalenii_PYR-1 GITTANGLPVSLLQTYIPS------------------------
MSMEG_5142|M.smegmatis_MC2_155 EVTRRNGVPHVFRQNDAPADIR---------------------
MAB_3192c|M.abscessus_ATCC_199 QITRDAGTVPGYRPVIPAAKCSTTVGQDSCAPLDPNGPTVALR
:* * ..