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STSEPSHAGFPISHVAQRTGLSIDALRWFEREGLFPRVPRDAGGRRRFSDDDIERVQLMLRLRRTGMPVR DMRRFIELLAGGEETHAERLELLFAQRVRILAAMERLTEDLRVVDFKVAYYTESVNGASAQSAGGKKN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4121c | - | - | 100% (139) | MerR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2246 | - | 3e-06 | 35.16% (91) | thiol-specific antioxidant related protein/peroxidoxin BcpB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0361 | hspR | 6e-05 | 32.32% (99) | HEAT shock protein transcriptional regulator HspR |
| M. gilvum PYR-GCK | Mflv_3212 | - | 5e-06 | 30.86% (81) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0353 | hspR | 6e-05 | 32.32% (99) | HEAT shock protein transcriptional repressor HspR |
| M. leprae Br4923 | MLBr_02493 | hspR | 3e-05 | 31.13% (106) | heat shock regulator |
| M. marinum M | MMAR_2990 | hspR_2 | 2e-07 | 32.67% (101) | heat shock protein transcriptional repressor HspR_2 |
| M. avium 104 | MAV_2720 | - | 7e-07 | 31.96% (97) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_1447 | - | 5e-08 | 33.02% (106) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_0931 | soxR | 1e-05 | 32.84% (67) | redox-sensitive transcriptional activator SoxR |
| M. ulcerans Agy99 | MUL_0596 | hspR | 3e-05 | 31.78% (107) | heat shock protein transcriptional repressor HspR |
| M. vanbaalenii PYR-1 | Mvan_4935 | - | 4e-18 | 37.82% (119) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4121c|M.abscessus_ATCC_199 --MSTSEP--------SHAGFPISHVAQRTGLSIDALRWFEREGLFPRVP
Mvan_4935|M.vanbaalenii_PYR-1 MVIVSSNPDCL-----ESHGVSIAEAAQRTGLSRHTLRYYERAGLIESVE
Mb0361|M.bovis_AF2122/97 ---MAKNPKD-----GESRTFLISVAAELAGMHAQTLRTYDRLGLVS-PR
Rv0353|M.tuberculosis_H37Rv ---MAKNPKD-----GESRTFLISVAAELAGMHAQTLRTYDRLGLVS-PR
MUL_0596|M.ulcerans_Agy99 ---MAKNSRE-----GEARTFLISVAAELAGMHAQTLRTYDRLGLVS-PR
MLBr_02493|M.leprae_Br4923 --MMTRNSRDP--RQQESRTFLISAAAELAGMHAQTLRTYDRLGLVS-PS
MMAR_2990|M.marinum_M ---MADRPGHAGGPAPDVGVYGISVTAELSGIAVQSLRLYERHGLVT-PA
MAV_2720|M.avium_104 ---MRGDP----TPRSARGVYGISVASELSGIPPQTLRHYERRGLLT-PA
Mflv_3212|M.gilvum_PYR-GCK --------------------MRIGKLAEATGATTATLRYYEDEGLLPPAE
TH_0931|M.thermoresistible__bu ---------------MGAHELTPSEMSARSGVAVSALHFYEREGLIT-SR
MSMEG_1447|M.smegmatis_MC2_155 ----MTVPG------TDQDLLQIGEVAARTELSVKTIRHYDEVGLVVPSA
. : : ::: :: **.
MAB_4121c|M.abscessus_ATCC_199 RDAGGRRRFSDDDIERVQLMLRL-RRTGMPVRDMRRFIELLAGGEETHAE
Mvan_4935|M.vanbaalenii_PYR-1 RSTSGRRQYAASDLDWFAFLVRL-RQTGMPITQMQQFARLRADGAATLEQ
Mb0361|M.bovis_AF2122/97 RTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIELTSQ-VEALQS
Rv0353|M.tuberculosis_H37Rv RTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIELTSQ-VEALQS
MUL_0596|M.ulcerans_Agy99 RTSGGGRRYSEHDVNLLRQVQQLSQEEGVNLAGIKRIIELTNQ-VEALQS
MLBr_02493|M.leprae_Br4923 RASGGGRRYSQHDVELLRQVQRLSQNEGVNLAGIKRIIELTNQ-VEALQL
MMAR_2990|M.marinum_M RSEGGTRRYSADDLVRLQRVSVL-IEAGINLAGISRILNLEDD-NAALAA
MAV_2720|M.avium_104 RSDGGTRRYSDDDLARLKRISQL-VDQGVNLVGVARILDLESK-NDQLKA
Mflv_3212|M.gilvum_PYR-GCK RSPAGYRDYAADTIARVGFIRRG-QAAGFSLAQIRQILDIRDSGHAPCTH
TH_0931|M.thermoresistible__bu RTAGNQRRYPREMLRRVAFIRMS-QRLGIPLARIREALATLPSDRVPTSK
MSMEG_1447|M.smegmatis_MC2_155 RSAGGFRLYTTDDVRRLMAIRRM-KPLGFTLDEMGRLLDALAVLDKPAAT
* .. * :. : . : *. : : .
MAB_4121c|M.abscessus_ATCC_199 RLELLFAQR-VRILAAMERLTEDLRVVDFKVAYYTESVN-----------
Mvan_4935|M.vanbaalenii_PYR-1 RRQLLDEHR-RHVEAAIAVQQGHLAALTDKIAHYEQLIT-----------
Mb0361|M.bovis_AF2122/97 RLQEMAEEL-AVLRANQRREVAVVPKSTALVVWK----------------
Rv0353|M.tuberculosis_H37Rv RLQEMAEEL-AVLRANQRREVAVVPKSTALVVWK----------------
MUL_0596|M.ulcerans_Agy99 RLQEMADEL-ETMRAKQRREVALVPRSTALVVWQRAGPAEPAFRHTPPGY
MLBr_02493|M.leprae_Br4923 KLQELTDEL-VMLRANQRRDLAVVPKSTALVLWQ----------------
MMAR_2990|M.marinum_M ANCDLLASN-RSLR---DAARAAVRLMNHGRSAE----------------
MAV_2720|M.avium_104 DYSALELLN-AQLKTRQNSERAAAPRQ--GRGEA----------------
Mflv_3212|M.gilvum_PYR-GCK VRDLLDIRL-TDLDEQISALVALRETIARLRQGAESVDPE----------
TH_0931|M.thermoresistible__bu DWAELSAGWRADLDERILHLQRLRDNLADCIGCGCLSLKTCALSN-----
MSMEG_1447|M.smegmatis_MC2_155 AAERATAAE--VVSDCHTRAQEACDRLTRHLAYAR---------------
:
MAB_4121c|M.abscessus_ATCC_199 --------GASAQSAGGKKN-
Mvan_4935|M.vanbaalenii_PYR-1 --------GRQGDQT------
Mb0361|M.bovis_AF2122/97 --------PRR----------
Rv0353|M.tuberculosis_H37Rv --------PRR----------
MUL_0596|M.ulcerans_Agy99 GPVPVLKNPERLDPVLKKPEM
MLBr_02493|M.leprae_Br4923 --------PRKPR--------
MMAR_2990|M.marinum_M --------NGEGGDTS-----
MAV_2720|M.avium_104 --------RREAV--------
Mflv_3212|M.gilvum_PYR-GCK --------SCSADDVCRYL--
TH_0931|M.thermoresistible__bu ---PDDALAARGPGAARL---
MSMEG_1447|M.smegmatis_MC2_155 ------ELTEQLAKVRG----