For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MQDKGTQVLARAATLLRAIGGGDLTGMSTTEIARTADLPRPTAHRLLTALAEEGLVDRDTTTGRWTLGPE LYLLGTGAAHRYDITDQSRDVIERLARETGESAFLSARRGDETVCILSREGSFPLRSHVLHEGIRFPLGV ASAGLAILSHLPDRDIDEYFTRSDLEPRWPASHSEAAIRERIAATRTTGYAVNPGLLVEGSWGMGAAVFD RTGRPAWALSLTGVETRFRPERRGEMGALLLELAHELTVRLRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4894 | - | - | 100% (253) | regulatory proteins, IclR |
| M. vanbaalenii PYR-1 | Mvan_4411 | - | 2e-16 | 28.70% (230) | regulatory proteins, IclR |
| M. vanbaalenii PYR-1 | Mvan_2134 | - | 1e-12 | 28.69% (251) | regulatory proteins, IclR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1802c | - | 7e-15 | 31.95% (241) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2399 | - | 1e-12 | 28.07% (171) | regulatory protein, IclR |
| M. tuberculosis H37Rv | Rv1773c | - | 7e-15 | 31.95% (241) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4380 | - | 4e-74 | 54.88% (246) | IclR family regulatory protein |
| M. marinum M | MMAR_1725 | - | 8e-15 | 31.75% (252) | transcriptional regulatory protein |
| M. avium 104 | MAV_3839 | - | 3e-12 | 30.18% (222) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_3335 | - | 2e-17 | 27.90% (233) | transcriptional regulator, IclR family protein, putative |
| M. thermoresistible (build 8) | TH_0967 | - | 3e-13 | 30.59% (170) | transcriptional regulator, IclR family protein, C- domain |
| M. ulcerans Agy99 | MUL_1967 | - | 4e-15 | 31.75% (252) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4894|M.vanbaalenii_PYR-1 -------------MQDKGTQVLARAATLLRAIGGGDLTG-MSTTEIARTA
MAB_4380|M.abscessus_ATCC_1997 -------MDAYGDLVTEAPSVVNRTAALLRAVSSDTGTG-VSTTELARRT
Mb1802c|M.bovis_AF2122/97 ---MPPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGH--LRLVDLCERL
Rv1773c|M.tuberculosis_H37Rv ---MPPTEGKSTTNRDEGIQVLRRAVAALDEIAAEPGH--LRLVDLCERL
MMAR_1725|M.marinum_M ------------MRQDSGIGVIDKAVGLLRATAESP----CGLAELCERT
MUL_1967|M.ulcerans_Agy99 ------------MRQDSGIGVIDKAVGLLRATAKSP----CGLAELCERT
MAV_3839|M.avium_104 -------------------------MGVLHTVAQSP----CGLAELCERT
Mflv_2399|M.gilvum_PYR-GCK -MADP--GNANAGPGAPGSQTLARGLNALQLVAGSPNG--LTVAQVAEDI
TH_0967|M.thermoresistible__bu -MTSVKGRGAPAERPAAVSQTLARGLSALQAVAGAPDG--LTVQQVADEV
MSMEG_3335|M.smegmatis_MC2_155 MNTPGDSAGAPNPGTSTSIRSMNSVLSTLRIFEEVATRQPIGVSDLSRVT
* ::.
Mvan_4894|M.vanbaalenii_PYR-1 DLPRPTAHRLLTALAEEGLVD-RDTTTGRWTLGPELYLLGTGAAHRYDIT
MAB_4380|M.abscessus_ATCC_1997 GIPRATAHRLLESLATEGLVE-RDARSGQWFLGPEIYVLGAASAPRYNIT
Mb1802c|M.bovis_AF2122/97 GLAKSTTRRLLVGLVEVGLVS-VDS-HGRFALGERLLGFGSVTGAHIAAA
Rv1773c|M.tuberculosis_H37Rv GLAKSTTRRLLVGLVEVGLVS-VDS-HGRFALGERLLGFGSVTGAHIAAA
MMAR_1725|M.marinum_M GLPRATAYRLAAALEVHRLLG-RDE-DGRWGLGPAITELAAHVDDPLLTA
MUL_1967|M.ulcerans_Agy99 GLPRATAYRLAAALEVHRLLG-RDE-DGRWGLGPAITELAAHVDDPLLTA
MAV_3839|M.avium_104 ELPRATAYRLAAALEVHRLLA-RGD-DGRWRLGPAVTELAAHVNDPLLAA
Mflv_2399|M.gilvum_PYR-GCK GVHRTIAYRLLSTLAQYRFVS-KGE-DGRYRSAAALAVLGASFDNNVRQL
TH_0967|M.thermoresistible__bu GVHRTIAYRLLGTLSQFRYVI-RGD-DGRYRPAAALALLGAAFDNNLRQY
MSMEG_3335|M.smegmatis_MC2_155 GIPKSTVQRCLVTLKQAGWLKVVDTAQTRWGVTARALSLGLRGAGEQDLR
: :. . * * : . :: :.
Mvan_4894|M.vanbaalenii_PYR-1 DQSRDVIERLARETGESAFLSARRGDETVCILSREGSFPLRSHVLHEGIR
MAB_4380|M.abscessus_ATCC_1997 EKAAADVAALARDTGESAFFSLRRGDHTVVLLAEDGDFPIRSHVLYEGAR
Mb1802c|M.bovis_AF2122/97 FR-PTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLR-AVSAVGLR
Rv1773c|M.tuberculosis_H37Rv FR-PTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLR-AVSAVGLR
MMAR_1725|M.marinum_M G--ATVLPRLRETTGESVQLYRREGTSRVCVAALEPPAGLR-DTVPVGAR
MUL_1967|M.ulcerans_Agy99 G--ATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLR-DTVPVGAR
MAV_3839|M.avium_104 G--SAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLR-DTVPVGAR
Mflv_2399|M.gilvum_PYR-GCK C--VPTLRGLADELGTTVSLLVAEGDQQVAIAVMVPTNVFYQLSFHEGSR
TH_0967|M.thermoresistible__bu S--VPVLRALADEVGTTVSLLVAEGDQQVAIAVIVPTQVFYQLSFHEGSR
MSMEG_3335|M.smegmatis_MC2_155 QLADPVIKRLAADTGETVHLALRDGNESVIIGRADTTKDVR-VILELGTR
* :. : * : . * *
Mvan_4894|M.vanbaalenii_PYR-1 FPLGVASAGLAILSHLPDRDIDEYFTRSDLEPRWPASHSEAAIRERIAAT
MAB_4380|M.abscessus_ATCC_1997 FPLGVVSSGMAVLAYLPDAAIHAYLERADLQSEWGNGFRIDAVWERVALT
Mb1802c|M.bovis_AF2122/97 FPLNGTANGKAALAALDDADAEAALCRLDPM-------VAEGLRREIVEI
Rv1773c|M.tuberculosis_H37Rv FPLNGTANGKAALAALDDADAEAALCRLDPM-------VAEGLRREIVEI
MMAR_1725|M.marinum_M LPMTAGSGAKVLLAHSDPATQQAVLP------------TAKFTDRVLAEV
MUL_1967|M.ulcerans_Agy99 LPMTAGSGAKVLLAHSDPATQQAVLP------------TAKFTDRVLAEV
MAV_3839|M.avium_104 LPMTAGSGAKVLLAHSDAATQKAVLA------------NAKFTERTLAEV
Mflv_2399|M.gilvum_PYR-GCK YPLDRGAAGIALLASMPPR---------------------PQERDLVRQA
TH_0967|M.thermoresistible__bu YPIDRGAAGIALLASMPPR---------------------PGERDLVRQT
MSMEG_3335|M.smegmatis_MC2_155 LPLQATSAGVAMLARLAPAEVAEVLSHEVDQVEGASVPSTDQLRREIEMT
*: : . . *: :
Mvan_4894|M.vanbaalenii_PYR-1 RTTGYAVNPGLLV-EGSWGMGAAVFDRTGRPAWALSLTGVETRFRPERRG
MAB_4380|M.abscessus_ATCC_1997 RKTGWAVNPGQVV-EGSWGMAAAVFDANQNPIGALTLTGIEARFNADRQP
Mb1802c|M.bovis_AF2122/97 RRTGIAFDRNEHT-PGIS-AAAIARRALGDNVIAISVPAPTARFLEKE-Q
Rv1773c|M.tuberculosis_H37Rv RRTGIAFDRNEHT-PGIS-AAAIARRALGDNVIAISVPAPTARFLEKE-Q
MMAR_1725|M.marinum_M RRRGWAQSVAERE-PGVASVSAPVRDGRGVVVAAISVSGPIDRIGRRPGA
MUL_1967|M.ulcerans_Agy99 RRRGWAQSVAERE-PGVASVSAPVRDGRGVVVAAISVSGPIDRIGRRPGA
MAV_3839|M.avium_104 RRRGWAQSVAERE-PGVASVSAPVRDSRGAVIAAISVSGPIDRIGRRPGA
Mflv_2399|M.gilvum_PYR-GCK RQQGWVITHGEIE-PNTFGLAVPVRRRQPSPPTCINLISHREDVVIDGRD
TH_0967|M.thermoresistible__bu REQGWVITHGEIE-PDTYGLAVPVRRRPHAPATCINLISHREDVVRRGKD
MSMEG_3335|M.smegmatis_MC2_155 AVRGYALNVSSWYRPHVCSVGVAVTDSMDRPIAGIAISIPEMRYDAANEA
* . .. . : :
Mvan_4894|M.vanbaalenii_PYR-1 EMGALLLELAHELTVRLRR-
MAB_4380|M.abscessus_ATCC_1997 VLGQLLLRHAHRLSRTVRR-
Mb1802c|M.bovis_AF2122/97 RIIAALRAAADSPDWTR---
Rv1773c|M.tuberculosis_H37Rv RIIAALRAAADSPDWTR---
MMAR_1725|M.marinum_M RWAADLLAAADELARRL---
MUL_1967|M.ulcerans_Agy99 RWAADLLAAADELARRL---
MAV_3839|M.avium_104 RWAADLVSAAEALTRRL---
Mflv_2399|M.gilvum_PYR-GCK AVIKAANELSAVLS------
TH_0967|M.thermoresistible__bu AVVRAAQELSAILN------
MSMEG_3335|M.smegmatis_MC2_155 TLAELANAAAAEINGLIRSA
: