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MDAYGDLVTEAPSVVNRTAALLRAVSSDTGTGVSTTELARRTGIPRATAHRLLESLATEGLVERDARSGQ WFLGPEIYVLGAASAPRYNITEKAAADVAALARDTGESAFFSLRRGDHTVVLLAEDGDFPIRSHVLYEGA RFPLGVVSSGMAVLAYLPDAAIHAYLERADLQSEWGNGFRIDAVWERVALTRKTGWAVNPGQVVEGSWGM AAAVFDANQNPIGALTLTGIEARFNADRQPVLGQLLLRHAHRLSRTVRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4380 | - | - | 100% (259) | IclR family regulatory protein |
| M. abscessus ATCC 19977 | MAB_3295 | - | 1e-12 | 29.49% (217) | IclR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4493 | - | 9e-12 | 29.63% (162) | IclR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1748 | - | 2e-11 | 33.10% (145) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3087 | - | 1e-13 | 25.60% (250) | transcriptional regulator, TrmB |
| M. tuberculosis H37Rv | Rv1719 | - | 2e-11 | 33.10% (145) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1725 | - | 5e-13 | 30.88% (217) | transcriptional regulatory protein |
| M. avium 104 | MAV_3513 | - | 1e-11 | 26.58% (222) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_3335 | - | 7e-17 | 27.42% (248) | transcriptional regulator, IclR family protein, putative |
| M. thermoresistible (build 8) | TH_2042 | - | 2e-13 | 27.78% (216) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1967 | - | 3e-13 | 30.41% (217) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4894 | - | 5e-74 | 54.88% (246) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4380|M.abscessus_ATCC_1997 MDAYGDLVTEAP---------------------SVVNRTAALLRAVSSDT
Mvan_4894|M.vanbaalenii_PYR-1 ------MQDKGT---------------------QVLARAATLLRAIGGGD
MMAR_1725|M.marinum_M ------MRQDSG--------------------IGVIDKAVGLLRATAESP
MUL_1967|M.ulcerans_Agy99 ------MRQDSG--------------------IGVIDKAVGLLRATAKSP
TH_2042|M.thermoresistible__bu ------MRKDSG--------------------IGVLDKAVSVLHSVAESP
Mb1748|M.bovis_AF2122/97 ------MSAEEQDTRSGG--------------IQVIARAAELLRVLQAHP
Rv1719|M.tuberculosis_H37Rv ------MSAEEQDTRSGG--------------IQVIARAAELLRVLQAHP
Mflv_3087|M.gilvum_PYR-GCK ------MAQHDKTSTTSPTDAPAA--------VQSVDRALQVLEIVAAHG
MAV_3513|M.avium_104 ------MPAKRARVAGPAAAAPAADALAPQYPIESVDNALKLLLLLGEQP
MSMEG_3335|M.smegmatis_MC2_155 ------MNTPGDSAGAPNPGTSTS--------IRSMNSVLSTLRIFEEVA
: : . *
MAB_4380|M.abscessus_ATCC_1997 GTG-VSTTELARRTGIPRATAHRLLESLATEGLVER-DARSGQWFLGPEI
Mvan_4894|M.vanbaalenii_PYR-1 LTG-MSTTEIARTADLPRPTAHRLLTALAEEGLVDR-DTTTGRWTLGPEL
MMAR_1725|M.marinum_M C----GLAELCERTGLPRATAYRLAAALEVHRLLGR-DED-GRWGLGPAI
MUL_1967|M.ulcerans_Agy99 C----GLAELCERTGLPRATAYRLAAALEVHRLLGR-DED-GRWGLGPAI
TH_2042|M.thermoresistible__bu C----GLAELCERTGLPRATAHRLAAGLEVHRLLAR-DGD-GRWCLGPAV
Mb1748|M.bovis_AF2122/97 GG--LSQAEIGERVGMARSTVSRILNALEDEGLVAS-RGARGPYRLGPEI
Rv1719|M.tuberculosis_H37Rv GG--LSQAEIGERVGMARSTVSRILNALEDEGLVAS-RGARGPYRLGPEI
Mflv_3087|M.gilvum_PYR-GCK Q---AGVTEIAAELGVHKSTVSRLVAVLEARGYVEQ-VSERGKYRLGFAI
MAV_3513|M.avium_104 E---IRLSEATRYLGVASSTAHRLLAMLAYRGFVRQ-DPVSKAYLPGPSL
MSMEG_3335|M.smegmatis_MC2_155 TRQPIGVSDLSRVTGIPKSTVQRCLVTLKQAGWLKVVDTAQTRWGVTARA
:: .: .*. * * : :
MAB_4380|M.abscessus_ATCC_1997 YVLGAASAPRYNITEKAAADVAALARDTGESAFFSLRRGDHTVVLLAEDG
Mvan_4894|M.vanbaalenii_PYR-1 YLLGTGAAHRYDITDQSRDVIERLARETGESAFLSARRGDETVCILSREG
MMAR_1725|M.marinum_M TELAAHVD--DPLLTAGATVLPRLRETTGESVQLYRREGTSRVCVAALEP
MUL_1967|M.ulcerans_Agy99 TELAAHVD--DPLLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEP
TH_2042|M.thermoresistible__bu TELAARVD--DPLLAAAAVVLPRLREITGESVQLYRREGTSRICVAALEP
Mb1748|M.bovis_AF2122/97 TRMATTVR--LGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVP
Rv1719|M.tuberculosis_H37Rv TRMATTVR--LGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVP
Mflv_3087|M.gilvum_PYR-GCK PRLAHVAGGQNDLVKLGQAACDMLSAGVGETANLAVLDADRIVNIVEAIG
MAV_3513|M.avium_104 TGVAFAIFGRLDIARSAAPIMRALSEQLRETVHVGMLDGASVRFVAAVEG
MSMEG_3335|M.smegmatis_MC2_155 LSLGLRGAGEQDLRQLADPVIKRLAADTGETVHLALRDGNESVIIGRADT
:. : * *:. . . :
MAB_4380|M.abscessus_ATCC_1997 DFPIRSHVLYEGARFPLGVVSSGMAVLAYLPDAAIHAYLERADLQSEWGN
Mvan_4894|M.vanbaalenii_PYR-1 SFPLRSHVLHEGIRFPLGVASAGLAILSHLPDRDIDEYFTRSDLEPRWPA
MMAR_1725|M.marinum_M PAGLR-DTVPVGARLPMTAGSGAKVLLAHSDPATQQAVLP----------
MUL_1967|M.ulcerans_Agy99 PAGLR-DTVPVGARLPMTAGSGAKVLLAHSDPATQQAVLP----------
TH_2042|M.thermoresistible__bu PAGLR-DTVPVGTRLPMTAGSGAKVLLAYADSTTQQAVLS----------
Mb1748|M.bovis_AF2122/97 PQRLR-AVSAVGESFPLYCCANGKALLAALPPERQARALP-SRLAPLTAN
Rv1719|M.tuberculosis_H37Rv PQRLR-AVSAVGESFPLYCCANGKALLAALPPERQARALP-SRLAPLTAN
Mflv_3087|M.gilvum_PYR-GCK PSEIT-LRTWVGQSCPAYATSSGKVLLAGLDPAELPARIR-PPLTEFTDS
MAV_3513|M.avium_104 PAAVR-VASRLGRALPAHCTSTGKVMLAQLSAAELRALLPRERLKRITAH
MSMEG_3335|M.smegmatis_MC2_155 TKDVR-VILELGTRLPLQATSAGVAMLARLAPAEVAEVLS-HEVDQVEGA
: * * : . .:*: :
MAB_4380|M.abscessus_ATCC_1997 G-FRIDAVWERVALTRKTGWAVNPGQVV-EGSWGMAAAVFDANQNPIGAL
Mvan_4894|M.vanbaalenii_PYR-1 S-HSEAAIRERIAATRTTGYAVNPGLLV-EGSWGMGAAVFDRTGRPAWAL
MMAR_1725|M.marinum_M ---TAKFTDRVLAEVRRRGWAQSVAERE-PGVASVSAPVRDGRGVVVAAI
MUL_1967|M.ulcerans_Agy99 ---TAKFTDRVLAEVRRRGWAQSVAERE-PGVASVSAPVRDGRGVVVAAI
TH_2042|M.thermoresistible__bu ---NAKFSERALAEVHKRGWAQSVAERE-PGVASVSAPVRDGRGTVVAAV
Mb1748|M.bovis_AF2122/97 TITDRAALRDELNRIRVDGVAYDREEQT-EGICAVGAVLRGVSVELVAVS
Rv1719|M.tuberculosis_H37Rv TITDRAALRDELNRIRVDGVAYDREEQT-EGICAVGAVLRGVSVELVAVS
Mflv_3087|M.gilvum_PYR-GCK TLCGLAELQDELAAVRERGWACVREELE-VGLNAVAAPVYDVHAQVIAAL
MAV_3513|M.avium_104 SIGSRAALETELAAIRERGYATNREESE-EGVASVAVPIPTRAPGLRLAL
MSMEG_3335|M.smegmatis_MC2_155 SVPSTDQLRREIEMTAVRGYALNVSSWYRPHVCSVGVAVTDSMDRPIAGI
: * * .:.. :
MAB_4380|M.abscessus_ATCC_1997 TLTGIEARFNADRQPVLGQLLLRHAHRLSRTVRR-----
Mvan_4894|M.vanbaalenii_PYR-1 SLTGVETRFRPERRGEMGALLLELAHELTVRLRR-----
MMAR_1725|M.marinum_M SVSGPIDRIGRRPGARWAADLLAAADELARRL-------
MUL_1967|M.ulcerans_Agy99 SVSGPIDRIGRRPGARWAADLLAAADELARRL-------
TH_2042|M.thermoresistible__bu SVSGPIDRIGRRPGARWAADLLAAAEALTRRL-------
Mb1748|M.bovis_AF2122/97 -VPVPAQRFYG-REAELAGALLAWVSKVDAWFNGTEDRK
Rv1719|M.tuberculosis_H37Rv -VPVPAQRFYG-REAELAGALLAWVSKVDAWFNGTEDRK
Mflv_3087|M.gilvum_PYR-GCK SVSGPSYRLAVDRFDEVAKQTVAAAEQISRRLGWTTRN-
MAV_3513|M.avium_104 NAAAPQNRLDAARYPAVAAALVAAAKEIGDQLG------
MSMEG_3335|M.smegmatis_MC2_155 AISIPEMRYDAANEATLAELANAAAAEINGLIRSA----
. * . . : .