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M. thermoresistible (build 8) TH_0967 (-)

annotation: transcriptional regulator, IclR family protein, C- domain protein
coordinates: 1914404 - 1915111
length: 236

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0967--100% (236)transcriptional regulator, IclR family protein, C- domain protein
M. thermoresistible (build 8)TH_3197-2e-3035.37% (229) PUTATIVE putative transcriptional regulatory protein
M. thermoresistible (build 8)TH_2042-7e-1226.24% (221) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3013-4e-1327.85% (219) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_2399-9e-9977.39% (230) regulatory protein, IclR
M. tuberculosis H37RvRv2989-4e-1327.85% (219) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3295-1e-1228.83% (222) IclR family transcriptional regulator
M. marinum MMMAR_4779-2e-8874.09% (220) transcriptional regulatory protein
M. avium 104MAV_0876-2e-9377.52% (218) transcriptional regulator
M. smegmatis MC2 155MSMEG_4868-1e-10582.89% (228) transcriptional regulator
M. ulcerans Agy99MUL_0348-2e-8874.09% (220) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_4247-1e-10078.26% (230) regulatory proteins, IclR

CLUSTAL 2.0.9 multiple sequence alignment


TH_0967|M.thermoresistible__bu      ---------MTSVKGRGAPAERPAAVSQTLARGLSALQAVAGAPDGLTVQ
MSMEG_4868|M.smegmatis_MC2_155      ---MPANAAQSAARTRVEGAPSAAPGSQTLARGLSALQAIADAPGGLTVQ
Mflv_2399|M.gilvum_PYR-GCK          -----------MADPGNANAGPGAPGSQTLARGLNALQLVAGSPNGLTVA
Mvan_4247|M.vanbaalenii_PYR-1       MNRPAGDQAPVTGEPGPATAGAGAPGSQTLARGLNALQLVAKSPTGLTVG
MMAR_4779|M.marinum_M               -------------------MTGSGAGSQTLARGLTALQLVAASPAGLSMQ
MUL_0348|M.ulcerans_Agy99           -------------------MTGSGAGSQTLARGLTALQLVAASPAGLSMQ
MAV_0876|M.avium_104                -------------------MTGSGTGSQTLARGLTALQMVADAPAGLTVQ
Mb3013|M.bovis_AF2122/97            --------------------MRQHSGIGVLDKAVGVLHAVAESPCGL--A
Rv2989|M.tuberculosis_H37Rv         --------------------MRQHSGIGVLDKAVGVLHAVAESPCGL--A
MAB_3295|M.abscessus_ATCC_1997      --------------------MRQHSGIGVLDKAVQVLTAIGDSPCGL--A
                                                            .   .* :.: .*  :. :* **   

TH_0967|M.thermoresistible__bu      QVADEVGVHRTIAYRLLGTLSQFRYVIRGDDGRYRPAAALALLGAAFDNN
MSMEG_4868|M.smegmatis_MC2_155      QVADHLGAHRTIAYRLLATLSQFRYVAKGEDGRYRPAAALAVLGSSFDNN
Mflv_2399|M.gilvum_PYR-GCK          QVAEDIGVHRTIAYRLLSTLAQYRFVSKGEDGRYRSAAALAVLGASFDNN
Mvan_4247|M.vanbaalenii_PYR-1       QVAEDIGVHRTIAYRLLSTLAQYRFVAKGEDGRYRSAAALAVLGASFDNN
MMAR_4779|M.marinum_M               EVADRVGVHRTIAYRLLLTLTQFRLVAKGEDGRFRPAAGLAVLGASFDHN
MUL_0348|M.ulcerans_Agy99           EVADRVGVHRTIAYRLLLTLTQFRLVAKGEDGRFRPAAGLAVLGASFDHN
MAV_0876|M.avium_104                QLADQVGVHRTIAYRLLTTLAEFRLVAKGEDGRYRPAAGLAVLGASFDRN
Mb3013|M.bovis_AF2122/97            ELCDRTDLPRATAYRLAAALEVHRLLGRGQDGHWRLGPAITELATHVDDP
Rv2989|M.tuberculosis_H37Rv         ELCDRTDLPRATAYRLAAALEVHRLLGRGQDGHWRLGPAITELATHVDDP
MAB_3295|M.abscessus_ATCC_1997      ELCERTGLPRATAHRLAAGLEVHRLLSRDGDGQWQLGAGLTELAAHVNDP
                                    ::.:  .  *: *:**   *  .* : :. **::: ...:: *.: .:  

TH_0967|M.thermoresistible__bu      LRQYSVPVLRALADEVGTTVSLLVAEGDQQVAIAVIVPTQVFYQLSFHEG
MSMEG_4868|M.smegmatis_MC2_155      VRQLAIPTLRTLADELGTTVSLLVAEGDQQVAIAVIVPSQVYYQLSFHEG
Mflv_2399|M.gilvum_PYR-GCK          VRQLCVPTLRGLADELGTTVSLLVAEGDQQVAIAVMVPTNVFYQLSFHEG
Mvan_4247|M.vanbaalenii_PYR-1       VRQLCVPTLRALADELGTTVSLLVAEGDQQVAIAVMVPTNVFYQLSFHEG
MMAR_4779|M.marinum_M               VRQLSLPTLRALADDLGTTVSLLVAEGDEQVALAVIVPTQVAYQLAFHEG
MUL_0348|M.ulcerans_Agy99           VRQLSLPTLRALADDLGTTVSLLVAEGDEQVALAVIVPTQVAYQLAFHEG
MAV_0876|M.avium_104                VRQLCLPTLRALADELGTTVSLLVAEGDQQVAIAVIVPSHVAYQLSFHEG
Mb3013|M.bovis_AF2122/97            LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEP-AAGLRDTVPVG
Rv2989|M.tuberculosis_H37Rv         LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEP-AAGLRDTVPVG
MAB_3295|M.abscessus_ATCC_1997      LLSASAQVLPKLREITGESVQLYRREGTVRICVAALEP-PAGLRDTVPVG
                                    :   .  .*  * :  * :*.:   **  ::.:*.: *  .  : :.  *

TH_0967|M.thermoresistible__bu      SRYPIDRGAAGIALLAS---------MPPRPGERDLVRQTREQGWVITHG
MSMEG_4868|M.smegmatis_MC2_155      SRHPLDRGAAGVALLAS---------MPPRPGERDLVRQTREQGWVITHG
Mflv_2399|M.gilvum_PYR-GCK          SRYPLDRGAAGIALLAS---------MPPRPQERDLVRQARQQGWVITHG
Mvan_4247|M.vanbaalenii_PYR-1       SRYPLDRGAAGIALLAS---------MPPRPGERDLVQQTRQQGWVITHG
MMAR_4779|M.marinum_M               SRYPLDRGAAGIALLAS---------MAARPGERELVAATRRRGWVTTFG
MUL_0348|M.ulcerans_Agy99           SRYPLDRGAAGIALLAS---------MAARPGERELVAATRRRGWVTTFG
MAV_0876|M.avium_104                SRYPLDRGAAGIALLAC---------MPPRPGERELVSRARERGWVTTYG
Mb3013|M.bovis_AF2122/97            ARLPMTAGSGAKVLLAHTDAATQAAVLPKAVFSARALAEVCRRGWAQSVA
Rv2989|M.tuberculosis_H37Rv         ARLPMTAGSGAKVLLAHTDAATQAAVLPKAVFSARALAEVCRRGWAQSVA
MAB_3295|M.abscessus_ATCC_1997      SRLPMSAGSGAKVLLAHSDPGTQAAVLPGATFTERALADVRKRGWAQSAA
                                    :* *:  *:.. .***          :.        :  . .:**. : .

TH_0967|M.thermoresistible__bu      EIEPDTYGLAVPVRRRPHAPATCINLISHREDVVRRG----KDAVVRAAQ
MSMEG_4868|M.smegmatis_MC2_155      EIEPNTYGLAVPVRRRPPSPPTCINLISHREDVVLGG----KDAVVRAAR
Mflv_2399|M.gilvum_PYR-GCK          EIEPNTFGLAVPVRRRQPSPPTCINLISHREDVVIDG----RDAVIKAAN
Mvan_4247|M.vanbaalenii_PYR-1       EIEPNTYGLAVPVRRRPPSPPTCINLISHREDVVLDG----RDSVIKAAA
MMAR_4779|M.marinum_M               EIEPNTYGLAVPVSRPAPAPPTCINLISHREDVVMRA----KGAVIDAAR
MUL_0348|M.ulcerans_Agy99           EIEPNTYGLAVPVSRPAPAPPTCINLISHREDVVMRA----KGAVIDAAR
MAV_0876|M.avium_104                EIEPNTYGLAVGVRRPAPSPPTCINLISHREDVVMRG----KDAVMRAAE
Mb3013|M.bovis_AF2122/97            EREPGVASVSAPVRDGRGVVIAAISVSGPIDRMGRRPGVRWAADLLSAAD
Rv2989|M.tuberculosis_H37Rv         EREPGVASVSAPVRDGRGVVIAAISVSGPIDRMGRRPGVRWAADLLSAAD
MAB_3295|M.abscessus_ATCC_1997      EREAGVASVSAPVRDRHGNVIAAISVSGPIDRMGRRPGARWAADLVAASE
                                    * *... .::. *        :.*.: .  : :           :: *: 

TH_0967|M.thermoresistible__bu      ELSAILN
MSMEG_4868|M.smegmatis_MC2_155      ELSAILH
Mflv_2399|M.gilvum_PYR-GCK          ELSAVLS
Mvan_4247|M.vanbaalenii_PYR-1       ELSEALN
MMAR_4779|M.marinum_M               QLSTQLS
MUL_0348|M.ulcerans_Agy99           QLSTQLS
MAV_0876|M.avium_104                QLSKLLS
Mb3013|M.bovis_AF2122/97            ALTRRL-
Rv2989|M.tuberculosis_H37Rv         ALTRRL-
MAB_3295|M.abscessus_ATCC_1997      AITARL-
                                     ::  *