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TVTSIRSRSADCRRFSIASTSLTFACRTEGAGSATRATVSVWGEVDAANAKHFAHTVREVAEGNAALILD LSEVNFMAFDGASALYAISAQLAREGVTWCVIASPAVSRVLELCDPEGLIPATTIPSVRGAKPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4700 | - | - | 100% (135) | anti-sigma-factor antagonist |
| M. vanbaalenii PYR-1 | Mvan_2530 | - | 4e-16 | 41.58% (101) | anti-sigma-factor antagonist |
| M. vanbaalenii PYR-1 | Mvan_0702 | - | 2e-11 | 40.96% (83) | anti-sigma-factor antagonist |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0529c | - | 6e-09 | 37.68% (69) | hypothetical protein Mb0529c |
| M. gilvum PYR-GCK | Mflv_2023 | - | 5e-54 | 76.30% (135) | anti-sigma-factor antagonist |
| M. tuberculosis H37Rv | Rv0516c | - | 6e-09 | 37.68% (69) | hypothetical protein Rv0516c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2512 | - | 2e-09 | 34.07% (91) | hypothetical protein MAB_2512 |
| M. marinum M | MMAR_0853 | - | 2e-07 | 29.91% (107) | hypothetical protein MMAR_0853 |
| M. avium 104 | MAV_4257 | - | 9e-15 | 41.11% (90) | STAS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1786 | - | 5e-12 | 38.46% (104) | STAS domain-containing protein |
| M. thermoresistible (build 8) | TH_2508 | - | 9e-13 | 38.00% (100) | PUTATIVE putative anti-sigma-factor antagonist |
| M. ulcerans Agy99 | MUL_0605 | - | 2e-07 | 29.91% (107) | hypothetical protein MUL_0605 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4700|M.vanbaalenii_PYR-1 ----MTVTSIRSRSADCRRFSIASTSLTFACRTEGAGSATRATVSVWGEV
Mflv_2023|M.gilvum_PYR-GCK ----MTVTSIHSRSADCRSFAIASTALAVACRTEGRGAQKCVTVSVRGEV
MSMEG_1786|M.smegmatis_MC2_155 ----MPTISVAKRSSPHSG-SHAPQRAHFTTEQINTAT---AVVTVHGDL
TH_2508|M.thermoresistible__bu ------MILPVPRPSPGGGEAVTCHAADFATRWVNSAT---VVIRVDGEL
MAV_4257|M.avium_104 -------MSVAQSWQ-------QSRTAQFTARWGLTG----TLITVDGEL
Mb0529c|M.bovis_AF2122/97 ---MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEI
Rv0516c|M.tuberculosis_H37Rv ---MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEI
MMAR_0853|M.marinum_M -------MGIAITASSFADRQKNGTFECSGAVVRAHCRHLATIVTIRGEI
MUL_0605|M.ulcerans_Agy99 -------MGIAITASSFADRQKNGTFECSGAVVRAHCRHLATIVTIRGEI
MAB_2512|M.abscessus_ATCC_1997 MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATGEI
. : *::
Mvan_4700|M.vanbaalenii_PYR-1 DAANAKHFAHTVREVAEGNAALILDLSEVNFMAFDGASALYAISAQLARE
Mflv_2023|M.gilvum_PYR-GCK DALNAKHFAHTVREMAGGSAALVLDLTEVSFLAFDGASALYAISAHLARE
MSMEG_1786|M.smegmatis_MC2_155 DASNAGLLTDYALKALTRNAKLVLDLSDVAFFGAACFTALHTLNVRCAGA
TH_2508|M.thermoresistible__bu DAANSPQLVDYALRHAGRIKYLVADLTGVEFFGIAGFSAAHDINGRCAHA
MAV_4257|M.avium_104 DAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSALHRINVICSAA
Mb0529c|M.bovis_AF2122/97 DAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAA
Rv0516c|M.tuberculosis_H37Rv DAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAA
MMAR_0853|M.marinum_M DAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHAA
MUL_0605|M.ulcerans_Agy99 DAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHAA
MAB_2512|M.abscessus_ATCC_1997 DAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVALDRVRRHCKVQ
** * . . :: *: : .:. :
Mvan_4700|M.vanbaalenii_PYR-1 GVTWCVIASPAVSRVLE----LCDPEGLIPATTIPSVRG---------AK
Mflv_2023|M.gilvum_PYR-GCK DVTWCVVPSPAVSRVVK----LCDPEGLIPLQDIASVRG---------VK
MSMEG_1786|M.smegmatis_MC2_155 DAEWVVVPSKAVTRVLR----ICDPDSGLTTAPDVVSALSR------KSD
TH_2508|M.thermoresistible__bu KLTWTLVPSPAVVRLLQ----ICDPDGTLPLNTTVPDSVWD------NGG
MAV_4257|M.avium_104 QTSWAMAPSPAVARLLR----LCDPDGTLPVTTPKAEPLLEPRRANGDES
Mb0529c|M.bovis_AF2122/97 GVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-DRR
Rv0516c|M.tuberculosis_H37Rv GVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-DRR
MMAR_0853|M.marinum_M GAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-SSR
MUL_0605|M.ulcerans_Agy99 GAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-SSR
MAB_2512|M.abscessus_ATCC_1997 GIDWTVIPGDAVTKLLT----LSGDMAAYPVNDAIPDVWKKLAQ------
* : .. ** . : .
Mvan_4700|M.vanbaalenii_PYR-1 PA----------
Mflv_2023|M.gilvum_PYR-GCK PA----------
MSMEG_1786|M.smegmatis_MC2_155 QR-PLQLVENT-
TH_2508|M.thermoresistible__bu SGGLFQLIPEAG
MAV_4257|M.avium_104 PGPLLQLVTKPR
Mb0529c|M.bovis_AF2122/97 RQLVLPLISRSA
Rv0516c|M.tuberculosis_H37Rv RQLVLPLISRSA
MMAR_0853|M.marinum_M RQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99 RQLMLSLVRKTA
MAB_2512|M.abscessus_ATCC_1997 ------------