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M. thermoresistible (build 8) TH_2508 (-)

annotation: putative anti-sigma-factor antagonist
coordinates: 532657 - 533088
length: 144

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2508--100% (144)putative anti-sigma-factor antagonist
M. thermoresistible (build 8)TH_2515-2e-0928.69% (122) PUTATIVE anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0529c-2e-0730.53% (95) hypothetical protein Mb0529c
M. gilvum PYR-GCKMflv_4788-2e-2947.06% (119) anti-sigma-factor antagonist
M. tuberculosis H37RvRv0516c-2e-0730.53% (95) hypothetical protein Rv0516c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2512-5e-1635.51% (107) hypothetical protein MAB_2512
M. marinum MMMAR_0853-1e-0632.63% (95) hypothetical protein MMAR_0853
M. avium 104MAV_4257-5e-2546.40% (125) STAS domain-containing protein
M. smegmatis MC2 155MSMEG_1786-7e-2449.17% (120) STAS domain-containing protein
M. ulcerans Agy99MUL_0605-7e-0732.63% (95) hypothetical protein MUL_0605
M. vanbaalenii PYR-1Mvan_1661-2e-2848.76% (121) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4788|M.gilvum_PYR-GCK          ---MPHVPGP---PTPPVPD------SLICHTARFDTTWTDPATAIVAGK
Mvan_1661|M.vanbaalenii_PYR-1       ---MPHVPDQHPAPPAPVSD------NVVCHTARFETRWPQPDTAIVSGL
MSMEG_1786|M.smegmatis_MC2_155      ---MPTISVAK--RSSPHSG------SHAPQRAHFTTEQINTATAVVTVH
TH_2508|M.thermoresistible__bu      ----MILPVPR--PSPGGGE------AVTCHAADFATRWVNSATVVIRVD
MAV_4257|M.avium_104                --------------MSVAQS------WQQSRTAQFTARWGLTG-TLITVD
Mb0529c|M.bovis_AF2122/97           MTTTIPTSKSACSVTTRPGN------AAVDYGGAQIRAYLHHLATVVTIR
Rv0516c|M.tuberculosis_H37Rv        MTTTIPTSKSACSVTTRPGN------AAVDYGGAQIRAYLHHLATVVTIR
MMAR_0853|M.marinum_M               ----MGIAITASSFADRQKN------GTFECSGAVVRAHCRHLATIVTIR
MUL_0605|M.ulcerans_Agy99           ----MGIAITASSFADRQKN------GTFECSGAVVRAHCRHLATIVTIR
MAB_2512|M.abscessus_ATCC_1997      ---MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRAT
                                                                    .           .::   

Mflv_4788|M.gilvum_PYR-GCK          GEVDAANGIRFVDYALRHADQTQWLVIDLSGLSFFSTAGFSALHTLNVQC
Mvan_1661|M.vanbaalenii_PYR-1       GELDAANGIDFVGYALRHSDRAHWLVVDLSGLTFFSTAGFSALHTLNVQC
MSMEG_1786|M.smegmatis_MC2_155      GDLDASNAGLLTDYALKALTRNAKLVLDLSDVAFFGAACFTALHTLNVRC
TH_2508|M.thermoresistible__bu      GELDAANSPQLVDYALRHAGRIKYLVADLTGVEFFGIAGFSAAHDINGRC
MAV_4257|M.avium_104                GELDAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSALHRINVIC
Mb0529c|M.bovis_AF2122/97           GEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDC
Rv0516c|M.tuberculosis_H37Rv        GEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDC
MMAR_0853|M.marinum_M               GEIDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEEC
MUL_0605|M.ulcerans_Agy99           GEIDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEEC
MAB_2512|M.abscessus_ATCC_1997      GEIDAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVALDRVRRHC
                                    *::** *   .     :       :: *:  : .:.   :     :   *

Mflv_4788|M.gilvum_PYR-GCK          VGEDIRWALVPGTAVHRVLR----ICDPDSALPICPDVPSALVAV-----
Mvan_1661|M.vanbaalenii_PYR-1       VSEDIRWALVPSKAVDRLLR----ICDPDHALPTCADVPTALTVV-----
MSMEG_1786|M.smegmatis_MC2_155      AGADAEWVVVPSKAVTRVLR----ICDPDSGLTTAPDVVSALSRK-----
TH_2508|M.thermoresistible__bu      AHAKLTWTLVPSPAVVRLLQ----ICDPDGTLPLNTTVPDSVWDN-----
MAV_4257|M.avium_104                SAAQTSWAMAPSPAVARLLR----LCDPDGTLPVTTPKAEPLLEPRRANG
Mb0529c|M.bovis_AF2122/97           RAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-
Rv0516c|M.tuberculosis_H37Rv        RAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-
MMAR_0853|M.marinum_M               HAAGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-
MUL_0605|M.ulcerans_Agy99           HAAGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-
MAB_2512|M.abscessus_ATCC_1997      KVQGIDWTVIPGDAVTKLLT----LSGDMAAYPVNDAIPDVWKKLAQ---
                                          *.: .. ** . *             .                 

Mflv_4788|M.gilvum_PYR-GCK          QEDPPRSFELITKTR
Mvan_1661|M.vanbaalenii_PYR-1       QQEPPRSLQLVAESR
MSMEG_1786|M.smegmatis_MC2_155      SDQ--RPLQLVENT-
TH_2508|M.thermoresistible__bu      GGSG-GLFQLIPEAG
MAV_4257|M.avium_104                DESPGPLLQLVTKPR
Mb0529c|M.bovis_AF2122/97           DRRRQLVLPLISRSA
Rv0516c|M.tuberculosis_H37Rv        DRRRQLVLPLISRSA
MMAR_0853|M.marinum_M               SSRRQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99           SSRRQLMLSLVRKTA
MAB_2512|M.abscessus_ATCC_1997      ---------------