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M. vanbaalenii PYR-1 Mvan_0702 (-)

annotation: anti-sigma-factor antagonist
coordinates: 743789 - 744247
length: 152

SITDPLPASSTQRVFRPDPTSFELREEHHRATFSACELPPSTVLVTIHGEVDATNSMALACYIEKRLGGA
RKLILDLQTVEFFAASGFAALSNINVVCARSGVRWTLLAGTHVRRLLRICDPVRELPVAEPAAKYSRTRP
SDRKLLVGRHD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0702--100% (152)anti-sigma-factor antagonist
M. vanbaalenii PYR-1Mvan_2530-1e-2138.46% (143) anti-sigma-factor antagonist
M. vanbaalenii PYR-1Mvan_1661-3e-1539.39% (99) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0529c-3e-0730.23% (86) hypothetical protein Mb0529c
M. gilvum PYR-GCKMflv_0203-2e-6781.21% (149) anti-sigma-factor antagonist
M. tuberculosis H37RvRv0516c-3e-0730.23% (86) hypothetical protein Rv0516c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2512-7e-1439.80% (98) hypothetical protein MAB_2512
M. marinum MMMAR_0853-3e-0836.49% (74) hypothetical protein MMAR_0853
M. avium 104MAV_4257-3e-1841.76% (91) STAS domain-containing protein
M. smegmatis MC2 155MSMEG_1786-2e-1740.17% (117) STAS domain-containing protein
M. thermoresistible (build 8)TH_2508-2e-1641.00% (100) PUTATIVE putative anti-sigma-factor antagonist
M. ulcerans Agy99MUL_0605-2e-0836.49% (74) hypothetical protein MUL_0605

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_0702|M.vanbaalenii_PYR-1       MSITDPLPASSTQRVFRPDPTSFELREEHHRATFSACELPPSTVLVTIHG
Mflv_0203|M.gilvum_PYR-GCK          MAISEALPPSSTQRVFRPDPTSFELREEHHRATFSACELPPTTVLVTIHG
MSMEG_1786|M.smegmatis_MC2_155      ---------MPTISVAKRSSPHSG-SHAPQRAHFTTEQINTATAVVTVHG
TH_2508|M.thermoresistible__bu      -----------MILPVPRPSPGGGEAVTCHAADFATRWVNSATVVIRVDG
MAV_4257|M.avium_104                ------------MSVAQSWQ-------QSRTAQFTARWGLTG-TLITVDG
Mb0529c|M.bovis_AF2122/97           -----MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRG
Rv0516c|M.tuberculosis_H37Rv        -----MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRG
MMAR_0853|M.marinum_M               ---------MGIAITASSFADRQKNGTFECSGAVVRAHCRHLATIVTIRG
MUL_0605|M.ulcerans_Agy99           ---------MGIAITASSFADRQKNGTFECSGAVVRAHCRHLATIVTIRG
MAB_2512|M.abscessus_ATCC_1997      --MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATG
                                                                   .           .::   *

Mvan_0702|M.vanbaalenii_PYR-1       EVDATNSMALACYIEKRLGGARKLILDLQTVEFFAASGFAALSNINVVCA
Mflv_0203|M.gilvum_PYR-GCK          EIDATNNMPLAHYIEKRIGDSRKLIVDLQTVEFFAASGFAALFNVNVVCH
MSMEG_1786|M.smegmatis_MC2_155      DLDASNAGLLTDYALKALTRNAKLVLDLSDVAFFGAACFTALHTLNVRCA
TH_2508|M.thermoresistible__bu      ELDAANSPQLVDYALRHAGRIKYLVADLTGVEFFGIAGFSAAHDINGRCA
MAV_4257|M.avium_104                ELDAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSALHRINVICS
Mb0529c|M.bovis_AF2122/97           EIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCR
Rv0516c|M.tuberculosis_H37Rv        EIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCR
MMAR_0853|M.marinum_M               EIDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECH
MUL_0605|M.ulcerans_Agy99           EIDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECH
MAB_2512|M.abscessus_ATCC_1997      EIDAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVALDRVRRHCK
                                    ::** *   :     :       :: *:  : .:.   :     :   * 

Mvan_0702|M.vanbaalenii_PYR-1       RSGVRWTLLAGTHVRRLLR----ICDPVRELPVAEPAAKYSRT-------
Mflv_0203|M.gilvum_PYR-GCK          RRGVRWQLLAGPHVRRLLR----VCDPQRELPVTGSSAKYTRT-------
MSMEG_1786|M.smegmatis_MC2_155      GADAEWVVVPSKAVTRVLR----ICDPDSGLTTAPDVVSALSR------K
TH_2508|M.thermoresistible__bu      HAKLTWTLVPSPAVVRLLQ----ICDPDGTLPLNTTVPDSVWD------N
MAV_4257|M.avium_104                AAQTSWAMAPSPAVARLLR----LCDPDGTLPVTTPKAEPLLEPRRANGD
Mb0529c|M.bovis_AF2122/97           AAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-D
Rv0516c|M.tuberculosis_H37Rv        AAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI-D
MMAR_0853|M.marinum_M               AAGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-S
MUL_0605|M.ulcerans_Agy99           AAGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEAN-S
MAB_2512|M.abscessus_ATCC_1997      VQGIDWTVIPGDAVTKLLT----LSGDMAAYPVNDAIPDVWKK-------
                                         * : ..  * . *             .      .           

Mvan_0702|M.vanbaalenii_PYR-1       -RPSDRKLLVGRHD
Mflv_0203|M.gilvum_PYR-GCK          -RPRDRKLLVGGYH
MSMEG_1786|M.smegmatis_MC2_155      SDQR-PLQLVENT-
TH_2508|M.thermoresistible__bu      GGSGGLFQLIPEAG
MAV_4257|M.avium_104                ESPGPLLQLVTKPR
Mb0529c|M.bovis_AF2122/97           RRRQLVLPLISRSA
Rv0516c|M.tuberculosis_H37Rv        RRRQLVLPLISRSA
MMAR_0853|M.marinum_M               SRRQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99           SRRQLMLSLVRKTA
MAB_2512|M.abscessus_ATCC_1997      --------LAQ---
                                            *