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TTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVL DLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLAD AIDRRRQLVLPLISRSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0516c | - | - | 100% (158) | hypothetical protein Rv0516c |
| M. tuberculosis H37Rv | Rv1365c | rsfA | 4e-06 | 28.85% (104) | anti-anti-sigma factor RSFA (anti-sigma factor antagonist) |
| M. tuberculosis H37Rv | Rv1904 | - | 1e-04 | 23.36% (137) | hypothetical protein Rv1904 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0529c | - | 2e-87 | 100.00% (158) | hypothetical protein Mb0529c |
| M. gilvum PYR-GCK | Mflv_0343 | - | 2e-24 | 45.71% (140) | anti-sigma-factor antagonist |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2512 | - | 6e-08 | 32.18% (87) | hypothetical protein MAB_2512 |
| M. marinum M | MMAR_0853 | - | 2e-39 | 53.02% (149) | hypothetical protein MMAR_0853 |
| M. avium 104 | MAV_4635 | - | 1e-37 | 54.55% (143) | STAS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0586 | - | 5e-20 | 40.91% (132) | STAS domain-containing protein |
| M. thermoresistible (build 8) | TH_2515 | - | 1e-28 | 45.77% (142) | PUTATIVE anti-sigma-factor antagonist |
| M. ulcerans Agy99 | MUL_0605 | - | 1e-39 | 53.02% (149) | hypothetical protein MUL_0605 |
| M. vanbaalenii PYR-1 | Mvan_0395 | - | 3e-24 | 47.14% (140) | anti-sigma-factor antagonist |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0343|M.gilvum_PYR-GCK ----------------MYGNPTFHCAGADIR----AHCRQLATVVKVAGR
Mvan_0395|M.vanbaalenii_PYR-1 ----------------MYGNPTFHCDGADIR----AHCRQLATVVTISGH
MSMEG_0586|M.smegmatis_MC2_155 ----------------------MVCDGASMR----AHHRQLATVVTVKGA
Rv0516c|M.tuberculosis_H37Rv MTTTIPTSKSACSVTTRPGNAAVDYGGAQIR----AYLHHLATVVTIRGE
Mb0529c|M.bovis_AF2122/97 MTTTIPTSKSACSVTTRPGNAAVDYGGAQIR----AYLHHLATVVTIRGE
MMAR_0853|M.marinum_M ----MGIAITASSFADRQKNGTFECSGAVVR----AHCRHLATIVTIRGE
MUL_0605|M.ulcerans_Agy99 ----MGIAITASSFADRQKNGTFECSGAVVR----AHCRHLATIVTIRGE
MAV_4635|M.avium_104 --------MTIAGTETRHDNCVFDCDGAQVR----AHHRHLATVVHIRGV
TH_2515|M.thermoresistible__bu -------MTVPIHAAHRFGNRPFDCSGAKIR----AQCRHLATVVTISGT
MAB_2512|M.abscessus_ATCC_1997 -MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATGE
. . : *.:* *
Mflv_0343|M.gilvum_PYR-GCK LDNANVERAGRYIDRFILPEKPFVLDLSEVDSFGEEAISLLFVIDDLCTA
Mvan_0395|M.vanbaalenii_PYR-1 LDDVNVETASHYVDRFILTEKPFVLDLSGVDSFTREAISLLFAIDDVCAS
MSMEG_0586|M.smegmatis_MC2_155 IGSENLDQISAYVRRLVIPEKSIVLDLSGVNSFAPQAVSLFYAIDARCGE
Rv0516c|M.tuberculosis_H37Rv IDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRA
Mb0529c|M.bovis_AF2122/97 IDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRA
MMAR_0853|M.marinum_M IDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHA
MUL_0605|M.ulcerans_Agy99 IDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHA
MAV_4635|M.avium_104 IDDANVDRISHHIRRFTLGENPVVLDVADVSQFAEAGISLLYAFDADCRA
TH_2515|M.thermoresistible__bu IDDSNADRVGSYISRFIPTEQAFVLDLSGLDTFSPAGISFLDRVDDACQT
MAB_2512|M.abscessus_ATCC_1997 IDAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVALDRVRRHCKV
:. * : : ...***: : * .: : . *
Mflv_0343|M.gilvum_PYR-GCK AGEEWSLIASRAVEQTLR------DSGIEFPAAGSVPEALNHFADAMVAR
Mvan_0395|M.vanbaalenii_PYR-1 AGVDWSMIASRAVEQTLR------DAGIEFPAAGSVPEALNHFADAMVTR
MSMEG_0586|M.smegmatis_MC2_155 LGVDWAVVASGAVLAELD------DDDAGVPLTASVPDALHHFAEGTMAR
Rv0516c|M.tuberculosis_H37Rv AGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRR
Mb0529c|M.bovis_AF2122/97 AGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRR
MMAR_0853|M.marinum_M AGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEANSSR
MUL_0605|M.ulcerans_Agy99 AGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEANSSR
MAV_4635|M.avium_104 AEVEWTLVASSAVTAVLD----DTGHDASFPIMRSVHEVLRDRADAIAVR
TH_2515|M.thermoresistible__bu AGMDWAVVCSPAVIKTLD-----ADQDSSYPVTDSVAAALHQFADVIAAR
MAB_2512|M.abscessus_ATCC_1997 QGIDWTVIPGDAVTKLLT----LSGDMAAYPVNDAIPDVWKKLAQ-----
:*::: . ** * * :: . .. *:
Mflv_0343|M.gilvum_PYR-GCK RRL-LPLLTKTA
Mvan_0395|M.vanbaalenii_PYR-1 RQL-LPLLTKTA
MSMEG_0586|M.smegmatis_MC2_155 RRL-LPLLVKSA
Rv0516c|M.tuberculosis_H37Rv RQLVLPLISRSA
Mb0529c|M.bovis_AF2122/97 RQLVLPLISRSA
MMAR_0853|M.marinum_M RQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99 RQLMLSLVRKTA
MAV_4635|M.avium_104 RRMALPLVKKTS
TH_2515|M.thermoresistible__bu RRVLLPLLGKSA
MAB_2512|M.abscessus_ATCC_1997 ------------