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M. vanbaalenii PYR-1 Mvan_2530 (-)

annotation: anti-sigma-factor antagonist
coordinates: 2671752 - 2672219
length: 155

VAVGTKTIYRPLTAVTDEQERCGHATFAVRRCSAHRMAIAVIGEIDAVNGRALGRYVERHTRISRQLVLD
LRAVDFFGSQGFTALYYISVHCARSDVDWVIVGSPAVRRLLAICDPDGELPLTDALSSALARLDRLAHGG
QHLVWTAKSGWHAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2530--100% (155)anti-sigma-factor antagonist
M. vanbaalenii PYR-1Mvan_0702-2e-2138.46% (143) anti-sigma-factor antagonist
M. vanbaalenii PYR-1Mvan_1661-4e-1739.45% (109) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1939-1e-0834.26% (108) hypothetical protein Mb1939
M. gilvum PYR-GCKMflv_3879-6e-5767.76% (152) anti-sigma-factor antagonist
M. tuberculosis H37RvRv1904-8e-0934.26% (108) hypothetical protein Rv1904
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2512-4e-1335.79% (95) hypothetical protein MAB_2512
M. marinum MMMAR_2800-3e-0832.41% (108) hypothetical protein MMAR_2800
M. avium 104MAV_4257-9e-2043.69% (103) STAS domain-containing protein
M. smegmatis MC2 155MSMEG_1786-7e-1740.74% (108) STAS domain-containing protein
M. thermoresistible (build 8)TH_2508-5e-2043.36% (113) PUTATIVE putative anti-sigma-factor antagonist
M. ulcerans Agy99MUL_2925-2e-0832.41% (108) hypothetical protein MUL_2925

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_2530|M.vanbaalenii_PYR-1       ----MVAVGTKTIYRPLTAVTDEQERCGHATFAVRRCSAHRMAIAVIGEI
Mflv_3879|M.gilvum_PYR-GCK          ----MVAIRTERIFAPSISSDEDQTRCGAAIFATRTCSPNRIAVAVVGEV
MSMEG_1786|M.smegmatis_MC2_155      -------MPTISVAKRSSPHSG-SHAPQRAHFTTEQINTATAVVTVHGDL
TH_2508|M.thermoresistible__bu      ---------MILPVPRPSPGGGEAVTCHAADFATRWVNSATVVIRVDGEL
MAV_4257|M.avium_104                ----------MSVAQSWQ-------QSRTAQFTARWGLTG-TLITVDGEL
Mb1939|M.bovis_AF2122/97            ---MRTVAIGPGAGPSSTRPSSQPSDLHSGLRAVTECTGSAVVVHVGGDI
Rv1904|M.tuberculosis_H37Rv         ---MRTVAIGPGAGPSSTRPSSQPSDLHSGLRAVTECTGSAVVVHVGGDI
MMAR_2800|M.marinum_M               MRRVNTVAMGSSPSSSSTRLSSPAGDPHTGLRAVTECTGSAVVVHVGGDV
MUL_2925|M.ulcerans_Agy99           ---MNTVAMGSSPSSSSTRLSSPAGDPHTGLRAVTECTGSAVVVHVGGDV
MAB_2512|M.abscessus_ATCC_1997      MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATGEI
                                                                 .  :.         : . *::

Mvan_2530|M.vanbaalenii_PYR-1       DAVNGRALGRYVERHTRISRQ---LVLDLRAVDFFGSQGFTALYYISVHC
Mflv_3879|M.gilvum_PYR-GCK          DAVNGRELARYVERHLRVSRQ---LVLDLRAVDFFGSQGFTALYYISVHC
MSMEG_1786|M.smegmatis_MC2_155      DASNAGLLTDYALKALTRNAK---LVLDLSDVAFFGAACFTALHTLNVRC
TH_2508|M.thermoresistible__bu      DAANSPQLVDYALRHAGRIKY---LVADLTGVEFFGIAGFSAAHDINGRC
MAV_4257|M.avium_104                DAANADQLAAYVQQSVNRSRR---VILDLRGLNFIGTAGFSALHRINVIC
Mb1939|M.bovis_AF2122/97            DASNEVAWQRLVSKSAAIAIAPGPFVIDIRDLDFMGSCAYAVLAQESVRC
Rv1904|M.tuberculosis_H37Rv         DASNEVAWQRLVSKSAAIAIAPGPFVIDIRDLDFMGSCAYAVLAQESVRC
MMAR_2800|M.marinum_M               DASNEVVWQRLVNRSAAIAIAPGPFVIDIRDLDFIGSCAYAVLAQESVRC
MUL_2925|M.ulcerans_Agy99           DASNEVVWQRLVNRSAAIAIAPGPFVIDIRDLDFIGSCAYAVLAQESVRC
MAB_2512|M.abscessus_ATCC_1997      DAVNANHLAEYATRYLDGHRT---LVLDLQGLRFFGTDGLVALDRVRRHC
                                    ** *       . :          .: *:  : *:*     .       *

Mvan_2530|M.vanbaalenii_PYR-1       ARSDVDWVIVGS-PAVRRLLAICDPDGELPLTDALSSALARLDR---LAH
Mflv_3879|M.gilvum_PYR-GCK          TRSDVDWAIVAS-PPVRRLLSICDPESELPLADDLTAALARLDR---RAQ
MSMEG_1786|M.smegmatis_MC2_155      AGADAEWVVVPS-KAVTRVLRICDPDSGLTTAPDVVSALSR------KSD
TH_2508|M.thermoresistible__bu      AHAKLTWTLVPS-PAVVRLLQICDPDGTLPLNTTVPDSVWD------NGG
MAV_4257|M.avium_104                SAAQTSWAMAPS-PAVARLLRLCDPDGTLPVTTPKAEPLLEPRRANGDES
Mb1939|M.bovis_AF2122/97            RRRGVNMRLVSNQPIVARTIAACGLRRLIPLYAMVETALAP------PPS
Rv1904|M.tuberculosis_H37Rv         RRRGVNMRLVSNQPIVARTIAACGLRRLIPLYATVETALAP------PPS
MMAR_2800|M.marinum_M               RRRGVNLRLVSNQPIVARTIAACGLRRLLPMYSSVEAALSP------VPN
MUL_2925|M.ulcerans_Agy99           RRRGVNLRLVSNQPIVARTIAACGLRRLLPMYSSVEAALSP------VPN
MAB_2512|M.abscessus_ATCC_1997      KVQGIDWTVIPG-DAVTKLLTLSGDMAAYPVNDAIPDVWKK------LAQ
                                            :  .   * : :  ..     .                    

Mvan_2530|M.vanbaalenii_PYR-1       GGQHLVWTAKSGWHAR
Mflv_3879|M.gilvum_PYR-GCK          RHTPFVWSARSVWRTG
MSMEG_1786|M.smegmatis_MC2_155      QR-PLQLVENT-----
TH_2508|M.thermoresistible__bu      SGGLFQLIPEAG----
MAV_4257|M.avium_104                PGPLLQLVTKPR----
Mb1939|M.bovis_AF2122/97            AH--------------
Rv1904|M.tuberculosis_H37Rv         AH--------------
MMAR_2800|M.marinum_M               GH--------------
MUL_2925|M.ulcerans_Agy99           GH--------------
MAB_2512|M.abscessus_ATCC_1997      ----------------