For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2517 (-)

annotation: putative site-specific recombinase, phage integrase family protein
coordinates: 1352921 - 1353787
length: 289

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2517 - - 100% (289) putative site-specific recombinase, phage integrase family protein
M. thermoresistible (build 8) TH_1542 xerD 2e-14 31.52% (184) tyrosine recombinase XerD
M. thermoresistible (build 8) TH_0846 xerC 2e-11 30.34% (234) PROBABLE INTEGRASE/RECOMBINASE XERC

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2918c xerC 1e-14 27.94% (247) site-specific tyrosine recombinase XerC
M. gilvum PYR-GCK Mflv_3500 xerD 5e-14 30.98% (184) site-specific tyrosine recombinase XerD
M. tuberculosis H37Rv Rv2646 - 4e-18 29.61% (233) integrase
M. leprae Br4923 MLBr_01365 xerD 2e-13 32.89% (152) site-specific tyrosine recombinase XerD
M. abscessus ATCC 19977 MAB_2366 xerD 8e-14 31.52% (184) site-specific tyrosine recombinase XerD
M. marinum M MMAR_1433 - 6e-15 32.54% (169) site-specific integrase
M. avium 104 MAV_0779 - 2e-39 50.96% (157) site-specific recombinase, phage integrase family protein
M. smegmatis MC2 155 MSMEG_3744 xerD 8e-14 29.90% (194) site-specific tyrosine recombinase XerD
M. ulcerans Agy99 MUL_1690 xerD 6e-14 34.23% (149) site-specific tyrosine recombinase XerD
M. vanbaalenii PYR-1 Mvan_3281 xerD 3e-14 30.98% (184) site-specific tyrosine recombinase XerD

CLUSTAL 2.0.9 multiple sequence alignment


TH_2517|M.thermoresistible__bu      ------------------------LESVQYPLVNTWRTWQFAQSLSKRTV
MAV_0779|M.avium_104                --------------------------------------------------
Mflv_3500|M.gilvum_PYR-GCK          ----------------MGVG-AVLDGQLQGYLDHLAIERGVAANTLSSYR
Mvan_3281|M.vanbaalenii_PYR-1       -------------MT-TGVDPAALDDQFQGYLDHLAIERGVAANTLSSYR
MSMEG_3744|M.smegmatis_MC2_155      -------------MTGTSALRAVLDEQVQGYLDHLTIERGVAANTLSSYR
MLBr_01365|M.leprae_Br4923          ------------------MTTAALQTQLQGYLDYLIIERSIAANTLSSYR
MUL_1690|M.ulcerans_Agy99           ------------------MSTLTLDTQLQGYLDHLAIERGVAANTLSSYR
MAB_2366|M.abscessus_ATCC_1997      ----------------MTAAVGLLDGEIQSYLDHLDVERGVAANTLSSYR
Mb2918c|M.bovis_AF2122/97           -----------------------MQAILDEFDEYLALQCGRSVHTRRAYL
MMAR_1433|M.marinum_M               MTKELAAVVDDDGVWQLRGTAAEQFGLVNEFLGYLADRN-FSPRTCRAYA
Rv2646|M.tuberculosis_H37Rv         -----MNTATRVRLARKRADRLNLKLIKNGHHFRLRDADEITLAVGHLGV
                                                                                      

TH_2517|M.thermoresistible__bu      DERVATVTRMANWCQTSPESATS-----EQIAEWLAAGDWMPR-------
MAV_0779|M.avium_104                --------------------------------------------------
Mflv_3500|M.gilvum_PYR-GCK          RDLRRYAEHLKARGVGDLAAVTE-----TDVSEFLVALRLGDP-------
Mvan_3281|M.vanbaalenii_PYR-1       RDLRRYAEHLASRGVTDLAGVAE-----ADVSEFLVSLRRGDP-------
MSMEG_3744|M.smegmatis_MC2_155      RDLRRYAEHLRQRGIDDLARVAE-----SDVSDFLVALRRGDP-------
MLBr_01365|M.leprae_Br4923          RDLIRYSKHLSDRGIEDLAKVGE-----HDVSEFLVALRRGDP-------
MUL_1690|M.ulcerans_Agy99           RDLRRYSKHLEDRGITDLAKVGE-----DDVSEFLVALRRGDP-------
MAB_2366|M.abscessus_ATCC_1997      RDLRRYQQHLADRKIDRLAEVCE-----TDVSDFVVTLRRGDP-------
Mb2918c|M.bovis_AF2122/97           GDLRSLFAFLADRGSS-LDALTL-----SVLRSWLAATAG----------
MMAR_1433|M.marinum_M               YDLLAFARWLRDEQLG-VAEVNV-----DVLLRFLTACREATLPGRPGGN
Rv2646|M.tuberculosis_H37Rv         VEAFLAAAKSQNKPPGPPPSLHAPPSWRRDIDDYLLNLNAAGQR-----P
                                                                                      

TH_2517|M.thermoresistible__bu      ---------------TRWTYHRALSAWFTWLQLQG---------------
MAV_0779|M.avium_104                --------------------------------------------------
Mflv_3500|M.gilvum_PYR-GCK          -----DGGVVPLSAVSAARALIAVRGLHRFAAAEG--------------I
Mvan_3281|M.vanbaalenii_PYR-1       -----DNGVVPLSAVSAARAVIAVRGLHRFAAAEG--------------I
MSMEG_3744|M.smegmatis_MC2_155      -----DAGVTALSAVSAARAVVAVRGLHRFAAAEG--------------L
MLBr_01365|M.leprae_Br4923          -----DSGVAALSAVSAARALIAVRGLHRFAVAEG--------------L
MUL_1690|M.ulcerans_Agy99           -----ESGVLGLSAVSAARALIAVRGLHRFAAAEG--------------L
MAB_2366|M.abscessus_ATCC_1997      -----ANGVPELSASSAARALIAVRGLHRFAAIEG--------------L
Mb2918c|M.bovis_AF2122/97           ---------AGAARTTLARRTSAVKAFTAWAVRRG--------------L
MMAR_1433|M.marinum_M               VYSIRDGRNQGYAPATINRRLAAISSLFAFREMRDPDARSLVGSSRAARL
Rv2646|M.tuberculosis_H37Rv         ATIRLRKTVLCAAAHGLGRPPADVTAEHLLDWLGKQQHLSPEGRKTYRST
                                                                                      

TH_2517|M.thermoresistible__bu      ------HRLDNPMLRLGDPKRPKSVP-----RPLSNADVARLLTTRMHTR
MAV_0779|M.avium_104                ----------------------------------------------MHHR
Mflv_3500|M.gilvum_PYR-GCK          AAIDVARDVKPPTPSRRLPKSLSIDE---VLALLEAAGGDSEADSPLTLR
Mvan_3281|M.vanbaalenii_PYR-1       TTVDVAREVKPPTPGRRLPKSLSIDE---VLALLEAAGGDGEADGPLTLR
MSMEG_3744|M.smegmatis_MC2_155      TENDVARAVKPPTPSRRLPKSLTLDE---VLALLEAAGGDSEADSPLTLR
MLBr_01365|M.leprae_Br4923          VDLDVARAVRPPTPGRRLPKSLTVDE---VLALLESVGGESRADGPLVLR
MUL_1690|M.ulcerans_Agy99           AALDVARAVRPPTPGRRLPKSLTIDE---VLALLEGAGGDNPADGPLTLR
MAB_2366|M.abscessus_ATCC_1997      APTDVARAVKPPTPNRRLPKSLTVEQ---VEALLNAAGGGG-SDGPLDLR
Mb2918c|M.bovis_AF2122/97           LAGDPAARLQVPKARRTLPAVLRQDQ---ALRAMAAAESGAEQGDPLALR
MMAR_1433|M.marinum_M               RSRGERSGLLAHTAKPKSRSQLRVREPRWLPRGLSREESAALLGSFRSWR
Rv2646|M.tuberculosis_H37Rv         LRGFFVWAYEMDRVRDYVADSLPKVRCPKQPPRPAGDDVWQAALAKADRR
                                                                                     *

TH_2517|M.thermoresistible__bu      TRAMVLLATFEGLRTFEIAKVRGEHFDLVSRTMTVTGKGGITATLPLHHR
MAV_0779|M.avium_104                TRVMILLAALGGLRVAEISRVRGEDIDIAKPAIHVVGKGKRSAWLPLHVL
Mflv_3500|M.gilvum_PYR-GCK          NRALLELLYSTGARISEAVGLDIDDVDTSARSVLLRGKGGKQRLIPIGRP
Mvan_3281|M.vanbaalenii_PYR-1       NRALLELLYSTGARISEAVGLDVDDVDTEARSVLLRGKGGKQRLIPIGRP
MSMEG_3744|M.smegmatis_MC2_155      NRALLELLYSTGARISEAVGLDVDDVDTQARSVLLHGKGGKQRLVPIGRP
MLBr_01365|M.leprae_Br4923          NRALLELLYSTGSRISEAVGLDVDDVDTQARTVLLQGKGGKQRLVPVGRP
MUL_1690|M.ulcerans_Agy99           NRALLELLYSTGSRISEAVGLDVDDIDTQARTVLLQGKGGKQRLVPVGRP
MAB_2366|M.abscessus_ATCC_1997      NRALLELLYSTGARISEAVGLDVDDVDVQARSVLLWGKGGKQRLVPVGRP
Mb2918c|M.bovis_AF2122/97           DRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQP
MMAR_1433|M.marinum_M               DRAIGGLMLLSGLRSAEVLGLRVSDIDIARRWVRVLGKGGKERSVPIDTD
Rv2646|M.tuberculosis_H37Rv         IELMIRLAGEAGLRRAEAAQAHTGDLMDGG-LLLVHGKGGKRRIVPISDY
                                     . :  *    * *  *       ..      : : ***     :*.   

TH_2517|M.thermoresistible__bu      VVEHAYRMPRKGYWFPG---------------RNGGHQRRESVGQTIKEA
MAV_0779|M.avium_104                LVDAALTMPTRGWWFPAN------------SRRPGDHVHSKSVSDIIGNA
Mflv_3500|M.gilvum_PYR-GCK          AVTALETYLVRGRPDLARRGRG---TPAIFLNARGGRLSRQSAWQVLQDA
Mvan_3281|M.vanbaalenii_PYR-1       AVSALDNYLVRGRPDLARRGRG---TPAIFLNARGGRLSRQSAWQVLQDA
MSMEG_3744|M.smegmatis_MC2_155      AVSALDAYLVRGRPDLARRGRG---TPAIFLNARGGRLSRQSAWQVLQDS
MLBr_01365|M.leprae_Br4923          AVQALDAYLVRGRSDLARRGPGMLATPAIFLNARGGRLSRQSAWQVLQDA
MUL_1690|M.ulcerans_Agy99           AVQALDAYLVRGRPELARRGRG---TPAIFLNARGGRLSRQSAWQVLQDA
MAB_2366|M.abscessus_ATCC_1997      AVEALQAYLVRGRPDLARRGRG--GVPALFLNSRGGRLSRQSAWQVLADA
Mb2918c|M.bovis_AF2122/97           AADALHAWLVDGRRALVTAESG----HALLLGARGRRLDVRQARTAVHQT
MMAR_1433|M.marinum_M               VAGAIQTYLLAERPETDADELF----VVAKGAHRGRPLTAAGLRTVFRYH
Rv2646|M.tuberculosis_H37Rv         LAALIRDTPHG----------------YLFPNGTGGHLTAEHVGKLVSRA
                                     .                                *           .   

TH_2517|M.thermoresistible__bu      ITRAG--AVGSAHQLRHWFGTALVEAGVDLRTVQTLLRHQNLSSTEIYTQ
MAV_0779|M.avium_104                MRRAG--VRGTPHGLRHWYGTTLLDDGADLRTVQELLRHRSLSTTQIYTR
Mflv_3500|M.gilvum_PYR-GCK          AGRAGVTATVSPHVLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTM
Mvan_3281|M.vanbaalenii_PYR-1       AERAGITATVSPHVLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTM
MSMEG_3744|M.smegmatis_MC2_155      AERAGIASAVSPHTLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTM
MLBr_01365|M.leprae_Br4923          AEHAGITSGVSPHMLRHSFATHLLEGGADIRVVQELMGHASVTTTQIYTL
MUL_1690|M.ulcerans_Agy99           AERADITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTL
MAB_2366|M.abscessus_ATCC_1997      AERAKISAAVSPHTLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTL
Mb2918c|M.bovis_AF2122/97           VAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTH
MMAR_1433|M.marinum_M               RERSGVAAGH-PHALRHSFGTALAEAGVDLSVIQALMGHDHVDSAAAYIH
Rv2646|M.tuberculosis_H37Rv         L-----PGDATMHTLRHRYATRAYRGSHNLRAVQQLLGHASIVTTERYTA
                                                * ***  .*     . :: .:* *: *  : ::  *  

TH_2517|M.thermoresistible__bu      VKEPRRADAIQLLDPFQLDMVALSASPWKEAA
MAV_0779|M.avium_104                VTDERRAAAVGRLNPFR------GAS------
Mflv_3500|M.gilvum_PYR-GCK          VTVNALREVWAGAHPRAR--------------
Mvan_3281|M.vanbaalenii_PYR-1       VTVTALREVWAGAHPRAR--------------
MSMEG_3744|M.smegmatis_MC2_155      VTVHTLREVWAGAHPRAQ--------------
MLBr_01365|M.leprae_Br4923          VTVQALREVWAGAHPRAK--------------
MUL_1690|M.ulcerans_Agy99           VTVHALREVWAGAHPRAT--------------
MAB_2366|M.abscessus_ATCC_1997      VTVSALREVWAGAHPRAR--------------
Mb2918c|M.bovis_AF2122/97           VAVARLRAVHERAHPRA---------------
MMAR_1433|M.marinum_M               LAPTFLREEFDAARARLRARS-----------
Rv2646|M.tuberculosis_H37Rv         LCDDEVRAAAAAAW------------------
                                    :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2517	-	-	100% (289)	putative site-specific recombinase, phage integrase family protein
M. thermoresistible (build 8)	TH_1542	xerD	2e-14	31.52% (184)	tyrosine recombinase XerD
M. thermoresistible (build 8)	TH_0846	xerC	2e-11	30.34% (234)	PROBABLE INTEGRASE/RECOMBINASE XERC