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MTVQHTSLRHIIDGAQFDAVLVRDDAAGAPPTVLVVHGMEGRSDAQLQFANRLAERGYQAIAVDLFGEDV SRGGMEATSAAMTGFLDDREALARRLATVFGTLTGAAEVDADRVAAIGFCFGGLCVLDLARAGHPLVGVA SFHGLLTPPPQPQQREVTAKVIVFHGWDDPFAPPEDVVALGREFSGRGIDWQLHAYGNTLHAFMAPFADD PARGVLFSESASRRAWTSAELFLAECFGTEIPAH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4080 | - | - | 100% (244) | dienelactone hydrolase |
| M. vanbaalenii PYR-1 | Mvan_3034 | - | 3e-08 | 30.04% (223) | dienelactone hydrolase |
| M. vanbaalenii PYR-1 | Mvan_2379 | - | 3e-07 | 26.14% (241) | dienelactone hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2787 | - | 1e-07 | 25.10% (243) | hypothetical protein Mb2787 |
| M. gilvum PYR-GCK | Mflv_3311 | - | 1e-08 | 35.86% (145) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2765 | - | 1e-07 | 25.10% (243) | hypothetical protein Rv2765 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3265c | - | 5e-11 | 37.93% (145) | hypothetical protein MAB_3265c |
| M. marinum M | MMAR_1955 | - | 4e-07 | 26.52% (230) | alanine rich hydrolase |
| M. avium 104 | MAV_0487 | - | 7e-08 | 30.25% (119) | dienelactone hydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_2444 | - | 2e-07 | 24.78% (226) | dienelactone hydrolase family protein |
| M. thermoresistible (build 8) | TH_0693 | - | 3e-09 | 25.56% (223) | PROBABLE ALANINE RICH HYDROLASE |
| M. ulcerans Agy99 | MUL_2786 | - | 6e-08 | 27.89% (147) | alanine rich hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2787|M.bovis_AF2122/97 --MPKTTDTAATPDGTCAVRLFTPDG------------------------
Rv2765|M.tuberculosis_H37Rv --MPKTTDTAATPDGTCAVRLFTPDG------------------------
MMAR_1955|M.marinum_M --MPIISDSVSTPDGTCPVRLFTPAG------------------------
TH_0693|M.thermoresistible__bu ------------------VTLHTPDG------------------------
MUL_2786|M.ulcerans_Agy99 --MRHVQDTVSTPDGSCPVSLFVPDT------------------------
Mflv_3311|M.gilvum_PYR-GCK --MTPLQRYIAEEIATDHVDGLMSRREALRRLALLGVGGAAATALIAACG
MAB_3265c|M.abscessus_ATCC_199 --MTPLQRYIAEEIATDHIEGLLTRREAFRRLALLGVGATAAGALISACG
MAV_0487|M.avium_104 MTDIDLTDLAAAHAGSQPLRGYLATP------------------------
MSMEG_2444|M.smegmatis_MC2_155 -----MTITISTPDG--PIDALLSTP------------------------
Mvan_4080|M.vanbaalenii_PYR-1 --MTVQHTSLRHIIDGAQFDAVLVRD------------------------
.
Mb2787|M.bovis_AF2122/97 --------------------------------------------------
Rv2765|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1955|M.marinum_M --------------------------------------------------
TH_0693|M.thermoresistible__bu --------------------------------------------------
MUL_2786|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3311|M.gilvum_PYR-GCK QNQQSAETTAEPSPTSDTPTSDAPPPGMDAALPTEPVTWAGPKGELQGAW
MAB_3265c|M.abscessus_ATCC_199 TGNK---PVAAPAPAN----SGAPPPGMDNVVVTEPITWRGPNGTLQGAW
MAV_0487|M.avium_104 --------------------------------------------------
MSMEG_2444|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4080|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2787|M.bovis_AF2122/97 ---PGRWPGVVMFPDAGGVRDTFDRMAAKLAGFGYVVLLPDVYYREGDWA
Rv2765|M.tuberculosis_H37Rv ---PGRWPGVVMFPDAGGVRDTFDRMAAKLAGFGYVVLLPDVYYREGDWA
MMAR_1955|M.marinum_M ---PGPWPGVIMFPDAGGVRETFEQMAATLAGHGYVVLLPDVYYREGDWT
TH_0693|M.thermoresistible__bu ---AGPWPGVVLFVDAGGTRDLMREMADRLAGYGYAVLVPDVYYRHGRWE
MUL_2786|M.ulcerans_Agy99 ---CEPVPGVVMYPDVGGFRPTFQEMAATLAGFGYAVLLPDMYYRHRGYA
Mflv_3311|M.gilvum_PYR-GCK AQAAEPRGGILVIHENKGLNDWTRSVAGRLAGAGYSSLAIDLLSERGGTA
MAB_3265c|M.abscessus_ATCC_199 ATAAEPRGTVLVIHENKGLNDWVRSVAGRLAGVGYSSLAIDLLSEEGGAS
MAV_0487|M.avium_104 -SGTGPWPGVVLIHEVFGIDDVMRRHTDRLAGLGYLTLAVDLFSAGGAAR
MSMEG_2444|M.smegmatis_MC2_155 -TGSGPWPGVVIIHDAIGYGPDNELVSERVAQAGYLAITPNLYSRGGRAR
Mvan_4080|M.vanbaalenii_PYR-1 -DAAGAPPTVLVVHGMEGRSDAQLQFANRLAERGYQAIAVDLFGEDVSRG
::: * : :* ** : ::
Mb2787|M.bovis_AF2122/97 PFDMKTAFGDPQERARIMFMIGTLTPDRVTRDADALLNYLASRPEVIGDR
Rv2765|M.tuberculosis_H37Rv PFDMKTAFGDPQERARIMFMIGTLTPDRVTRDADALLNYLASRPEVIGDR
MMAR_1955|M.marinum_M PFAMETVFGDADERARLMFMLGTLTPDRVTRDAGAYFDYLATRPQVSGER
TH_0693|M.thermoresistible__bu PFDMRTVFGDPSERARLYRMIRSITPDMMETDARAFFDFLQSRPEVKGDR
MUL_2786|M.ulcerans_Agy99 PFSLPSAFTDPGERARMMALGDSLIPDMMASDADAYFDYLSTRAELRDNR
Mflv_3311|M.gilvum_PYR-GCK TFADP---------AEATAALGARTPEDMVADLRSGIAEVQRRTPDK--K
MAB_3265c|M.abscessus_ATCC_199 AFKDP---------AEATGTLGRIAPERFIADLKSGVDEILRRVPGK--P
MAV_0487|M.avium_104 CLIST---------MTAMIRGRGRAFADIAAARDYLAGSADCTG-----K
MSMEG_2444|M.smegmatis_MC2_155 CITRM---------FRDLLTQRGRALDDILAARDHLKSLPECTG-----T
Mvan_4080|M.vanbaalenii_PYR-1 GMEAT----------SAAMTGFLDDREALARRLATVFGTLTGAAEVDADR
: .
Mb2787|M.bovis_AF2122/97 FGVCGYCMGGRMSVVVAGRLPDRVAAAAAFHPGGLVANSPDSPHLLADRI
Rv2765|M.tuberculosis_H37Rv FGVCGYCMGGRMSVVVAGRLPDRVAAAAAFHPGGLVANSPDSPHLLADRI
MMAR_1955|M.marinum_M FGVCGYCMGGRISVLLAGRQPDRVAAAASFHGGGLVTDNPDSPHLLADRM
TH_0693|M.thermoresistible__bu FGVFGYCMGGRMSVTVAGRVPDRVAAAASFHAAGLVTDDPTSPHLLAERI
MUL_2786|M.ulcerans_Agy99 FGVCGYCRGGRVSMIVAGRCPDRVAAVASFHGSQLAADSPNSPHLLASRM
Mflv_3311|M.gilvum_PYR-GCK VAAIGFCMGGGLVWRLLAAGTPELAAAFPFYG-----PTPEAPDFAGSRD
MAB_3265c|M.abscessus_ATCC_199 AGAVGFCFGGGLVWQLLAAGEPRLAAAAPFYG-----PLPDNPDFSRSK-
MAV_0487|M.avium_104 VGVIGFCMGGGFALLTANTG---YDAAAVNYG-----QLPRHLDTALAGA
MSMEG_2444|M.smegmatis_MC2_155 VGVVGFCSGGQFALIMGPKG---FAASAPFYGT----PLPRHLDRTLDAS
Mvan_4080|M.vanbaalenii_PYR-1 VAAIGFCFGG-LCVLDLARAGHPLVGVASFHG-----LLTPPPQPQQREV
.. *:* ** . . : . .
Mb2787|M.bovis_AF2122/97 SATVYIGGAENDPSFTADHAEKLDKAFSAAGVPHRIECYP-AAHGFAVP-
Rv2765|M.tuberculosis_H37Rv SATVYIGGAENDPSFTADHAEKLDKAFSAAGVPHRIECYP-AAHGFAVP-
MMAR_1955|M.marinum_M TARLYVGGAQNDPSFTTDHAEQLEKALTAAGVEHTIEWYP-GAHGFAVP-
TH_0693|M.thermoresistible__bu KATVYVAGAQDDDGFTPAHAETLGKALTDAGVEHTIEFYP-AGHGFAVP-
MUL_2786|M.ulcerans_Agy99 RAKVYVAAADNDELFPPQQAATLRRALTAAGVDHTIETYA-AEHGFAVA-
Mflv_3311|M.gilvum_PYR-GCK VAVLAFYGELDQRVNATE--PDARAALEKAGLVHEIVIEPGANHAFFN--
MAB_3265c|M.abscessus_ATCC_199 AAVLAFYGELDERVTASK--DQAADALRRGGLLHEIAVEPGADHAFFN--
MAV_0487|M.avium_104 CPIVGSYGGRDPSLRGAT--RKLNEALTKAGIEHDVKEYPAASHAFLNDD
MSMEG_2444|M.smegmatis_MC2_155 CPIVASFGRRDPLGIGAP--ARLRRVVEAKNIPADIKVYPSAGHSFANIL
Mvan_4080|M.vanbaalenii_PYR-1 TAKVIVFHGWDDPFAPPEDVVALGREFSGRGIDWQLHAYGNTLHAFMAPF
. : : . . .: : *.*
Mb2787|M.bovis_AF2122/97 -------------DNPSYDAAADERHWAAMTETFGAALN-------
Rv2765|M.tuberculosis_H37Rv -------------DNPSYDAAADERHWAAMTETFGAALN-------
MMAR_1955|M.marinum_M -------------DNPPYDEACAQRHWTAMTDLFAATLSR------
TH_0693|M.thermoresistible__bu -------------DNLPYDEQAAERHWDALRALFDRELSG------
MUL_2786|M.ulcerans_Agy99 -------------DNPGYDADAARRHWDALRDFFGSTLGAQPGNTG
Mflv_3311|M.gilvum_PYR-GCK ------------DTGDRYDPAAAADAWERTLAWLTAHVG-------
MAB_3265c|M.abscessus_ATCC_199 ------------DSGPRYNASAAVDAWQRLLGWLGQHIG-------
MAV_0487|M.avium_104 EAGPRILRPLLRVAGIGPEPDSAQDAWNRIAAFFATHLH-------
MSMEG_2444|M.smegmatis_MC2_155 PA-----QPLLRVTGFGYDEAATTDAWTRVFAFFDEHLKPKTAGQA
Mvan_4080|M.vanbaalenii_PYR-1 ADDP--------ARGVLFSESASRRAWTSAELFLAECFGTEIPAH-
. . . * : .