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VRHVQDTVSTPDGSCPVSLFVPDTCEPVPGVVMYPDVGGFRPTFQEMAATLAGFGYAVLLPDMYYRHRGY APFSLPSAFTDPGERARMMALGDSLIPDMMASDADAYFDYLSTRAELRDNRFGVCGYCRGGRVSMIVAGR CPDRVAAVASFHGSQLAADSPNSPHLLASRMRAKVYVAAADNDELFPPQQAATLRRALTAAGVDHTIETY AAEHGFAVADNPGYDADAARRHWDALRDFFGSTLGAQPGNTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2786 | - | - | 100% (252) | alanine rich hydrolase |
| M. ulcerans Agy99 | MUL_2177 | - | 1e-82 | 58.51% (241) | alanine rich hydrolase |
| M. ulcerans Agy99 | MUL_2272 | - | 8e-12 | 27.17% (254) | hypothetical protein MUL_2272 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2787 | - | 1e-77 | 57.74% (239) | hypothetical protein Mb2787 |
| M. gilvum PYR-GCK | Mflv_4008 | - | 2e-76 | 56.02% (241) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2765 | - | 1e-77 | 57.74% (239) | hypothetical protein Rv2765 |
| M. leprae Br4923 | MLBr_01444 | - | 2e-11 | 25.78% (256) | putative dienelactone hydrolase |
| M. abscessus ATCC 19977 | MAB_3183c | - | 7e-64 | 50.21% (239) | dienelactone hydrolase |
| M. marinum M | MMAR_3553 | - | 1e-146 | 97.62% (252) | alanine rich hydrolase |
| M. avium 104 | MAV_3654 | - | 6e-83 | 61.41% (241) | hydrolase |
| M. smegmatis MC2 155 | MSMEG_2669 | - | 3e-71 | 51.43% (245) | hydrolase |
| M. thermoresistible (build 8) | TH_0693 | - | 3e-72 | 57.46% (228) | PROBABLE ALANINE RICH HYDROLASE |
| M. vanbaalenii PYR-1 | Mvan_2379 | - | 1e-77 | 56.43% (241) | dienelactone hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2786|M.ulcerans_Agy99 MRHVQDTVSTPDGSCPVSLFVPDTCEPVPGVVMYPDVGGFRPTFQEMAAT
MMAR_3553|M.marinum_M MRHVQDTVSTPDGSCPVSLFVPDTCEPVPGVVMYPDVGGFRPTFQEMAAT
Mflv_4008|M.gilvum_PYR-GCK MPTITDTVTTTDGSCPVTLHTPDGDGPWRGIVMYPDAGGVRPTFRTMADQ
Mvan_2379|M.vanbaalenii_PYR-1 MPRITDTVTTADGDCPVSLHTPDGGGPWRGIVMYPDAGGARPTFRAMADK
MSMEG_2669|M.smegmatis_MC2_155 MPTIKDTITTPDGTCPVTVATPEGSGPWPGVVLFPDAGGLRPTMEEMAAK
Mb2787|M.bovis_AF2122/97 MPKTTDTAATPDGTCAVRLFTPDGPGRWPGVVMFPDAGGVRDTFDRMAAK
Rv2765|M.tuberculosis_H37Rv MPKTTDTAATPDGTCAVRLFTPDGPGRWPGVVMFPDAGGVRDTFDRMAAK
MAV_3654|M.avium_104 MPKITDSISTADGTCPVRLFFPDGSGPWPGVVMYPDAGGVRDTFDQMAAE
TH_0693|M.thermoresistible__bu ----------------VTLHTPDGAGPWPGVVLFVDAGGTRDLMREMADR
MAB_3183c|M.abscessus_ATCC_199 MQRRDAQILTPDGLCSATLHLPDQPG--PAVVLYPDAGGARDVMRAMGDR
MLBr_01444|M.leprae_Br4923 --MTKIQIDAPDGPIDALLSVPPGPEPWPGVVVIHDAIGYEPDKESTNNH
. : * .:*: *. * .
MUL_2786|M.ulcerans_Agy99 LAGFGYAVLLPDMYYRHRGYAPFSLPSAFTDPGERARMMALGDSLIPDMM
MMAR_3553|M.marinum_M LAGFGYAVLLPDMYYRHRGYAPFSLPSAFTDPGERARMMALGDSLIPDMM
Mflv_4008|M.gilvum_PYR-GCK LAGHGYAVLLPDVYYREGDWAPFTMSTVFGDAAERRRLFGMISKVTPERM
Mvan_2379|M.vanbaalenii_PYR-1 LAGYGYAVLVPDVYYREGDWAPFTIATAFDDDVERRRLFSFMAKVTPEVM
MSMEG_2669|M.smegmatis_MC2_155 LAGFGYVVLVPDVYYRIPNWGPINLNTVFSDQDERKKLFEMMGTLTPEVI
Mb2787|M.bovis_AF2122/97 LAGFGYVVLLPDVYYREGDWAPFDMKTAFGDPQERARIMFMIGTLTPDRV
Rv2765|M.tuberculosis_H37Rv LAGFGYVVLLPDVYYREGDWAPFDMKTAFGDPQERARIMFMIGTLTPDRV
MAV_3654|M.avium_104 LAGFGYAVLLPDVYYRSGEWAPFDMATVFADQQERNRLFAMIGSVTPDRM
TH_0693|M.thermoresistible__bu LAGYGYAVLVPDVYYRHGRWEPFDMRTVFGDPSERARLYRMIRSITPDMM
MAB_3183c|M.abscessus_ATCC_199 LASWGYVVLVPDVYYREGNWQPFNMATAFGDTQERGRLFATMGTLTPDRI
MLBr_01444|M.leprae_Br4923 IAMAGYVAITPNLYSR-GSRARCITRVMRELLTKRGRAFDDILATR----
:* **..: *::* * :* :
MUL_2786|M.ulcerans_Agy99 ASDADAYFDYLSTRAELRDNRFGVCGYCRGGRVSMIVAGRCPDRVAAVAS
MMAR_3553|M.marinum_M ASDADAYFDYLSTRAEVRDNRFGVCGYCRGGRISMIVAGRCPDRVAAVAS
Mflv_4008|M.gilvum_PYR-GCK ESDAVAFFDYLADRPEVSGETFGTTGYCMGGRTSLVVAGRVPQRVAAAMS
Mvan_2379|M.vanbaalenii_PYR-1 AADATAFFDYLAGRPEVRGDTFGTTGYCMGGRTSLVLAGRLPDRVSAAMS
MSMEG_2669|M.smegmatis_MC2_155 ASDAEAFFDYLAARPDVTGEKFGTTGYCMGGRASLIVATRVPDRVAAALS
Mb2787|M.bovis_AF2122/97 TRDADALLNYLASRPEVIGDRFGVCGYCMGGRMSVVVAGRLPDRVAAAAA
Rv2765|M.tuberculosis_H37Rv TRDADALLNYLASRPEVIGDRFGVCGYCMGGRMSVVVAGRLPDRVAAAAA
MAV_3654|M.avium_104 ATDAAAFFDYLAARPEVSGDRFGVCGYCMGGRTSLIVAGRLPDRVAAAAS
TH_0693|M.thermoresistible__bu ETDARAFFDFLQSRPEVKGDRFGVFGYCMGGRMSVTVAGRVPDRVAAAAS
MAB_3183c|M.abscessus_ATCC_199 DADAGSFLDFLADQPEVTGELVGLTGYCMGGRISLRVAATHASRVGAVAS
MLBr_01444|M.leprae_Br4923 --------DYLLAMPKCSG-RVGIAGFCMGGRFALVMS---PKGFDASAP
::* .. . .* *:* *** :: :: .. . * .
MUL_2786|M.ulcerans_Agy99 FHGSQLAA-DSPNSPHLLASRMRAKVYVAAADNDELFPPQQAATLRRALT
MMAR_3553|M.marinum_M FHGSQLAA-DNPNSPHLLASRMRAKVYVAAADNDELFPRQQAATLRRALT
Mflv_4008|M.gilvum_PYR-GCK FHGGGLVT-DDAESPHLLADRIRAAVYVGAAHNDNSFTRADGETLDKALS
Mvan_2379|M.vanbaalenii_PYR-1 FHGGGLAT-DDPHSPHLLADQMRAAVYVGAARSDRSFTTEDGERLEKALT
MSMEG_2669|M.smegmatis_MC2_155 FHGGRIAVEDDPDSPHLLADKIQAVVYVAGAENDASFTEDDAKRLEDALS
Mb2787|M.bovis_AF2122/97 FHPGGLVA-NSPDSPHLLADRISATVYIGGAENDPSFTADHAEKLDKAFS
Rv2765|M.tuberculosis_H37Rv FHPGGLVA-NSPDSPHLLADRISATVYIGGAENDPSFTADHAEKLDKAFS
MAV_3654|M.avium_104 FHGGGLVT-DSDDSPHLLADRMSATVYVGGAQDDASFTTDHAEQLDKALT
TH_0693|M.thermoresistible__bu FHAAGLVT-DDPTSPHLLAERIKATVYVAGAQDDDGFTPAHAETLGKALT
MAB_3183c|M.abscessus_ATCC_199 FHGGNLAKADDLNSPHHLAGRITGVVLIAAAEEDASFPAEQEQLLGQVLT
MLBr_01444|M.leprae_Br4923 FYGTPLPR-------NLSETLNGACPIVASFGGRDPLGIGAPKRLRQATQ
*: : : . :.. : * .
MUL_2786|M.ulcerans_Agy99 AAGVDHTIETYA-AEHGFAVADN---------PGYDADAARRHWDALRDF
MMAR_3553|M.marinum_M AAGVDHTIETYA-AEHGFAVADN---------PGYDADAAHRHWDALRDF
Mflv_4008|M.gilvum_PYR-GCK AAGVEHTVDWYS-AQHGFAVPDN---------GPYDESAARRHWDAMQSF
Mvan_2379|M.vanbaalenii_PYR-1 STGVEHTIEWYP-AFHGFAVPDN---------GPYDEPAARRHWEAMRSF
MSMEG_2669|M.smegmatis_MC2_155 GASVEHTIEFYP-AGHGFAVPDHL--------SVYDEAAAQRHWENTERV
Mb2787|M.bovis_AF2122/97 AAGVPHRIECYP-AAHGFAVPDN---------PSYDAAADERHWAAMTET
Rv2765|M.tuberculosis_H37Rv AAGVPHRIECYP-AAHGFAVPDN---------PSYDAAADERHWAAMTET
MAV_3654|M.avium_104 AAGVRHTIEWYS-AAHGFAVPDN---------APYDPAAAERHWDAMRDV
TH_0693|M.thermoresistible__bu DAGVEHTIEFYP-AGHGFAVPDN---------LPYDEQAAERHWDALRAL
MAB_3183c|M.abscessus_ATCC_199 DAGVRHTIETYP-AKHGFAVTDN---------PTYDEGAAQRHWKALEDL
MLBr_01444|M.leprae_Br4923 TRHITTDIKVYPDAGHSFANKLPGQPLMRITGFGYNQAATEDAWSRVFAF
: :. *. * *.** *: * . *
MUL_2786|M.ulcerans_Agy99 FGSTLGAQPGNTG
MMAR_3553|M.marinum_M FGSTLGAQPGSTG
Mflv_4008|M.gilvum_PYR-GCK FAAHLV-------
Mvan_2379|M.vanbaalenii_PYR-1 FATHLV-------
MSMEG_2669|M.smegmatis_MC2_155 FGAALASA-----
Mb2787|M.bovis_AF2122/97 FGAALN-------
Rv2765|M.tuberculosis_H37Rv FGAALN-------
MAV_3654|M.avium_104 FAAALPR------
TH_0693|M.thermoresistible__bu FDRELSG------
MAB_3183c|M.abscessus_ATCC_199 YGATLGH------
MLBr_01444|M.leprae_Br4923 FDKHLRTD-----
: *