For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TPLQRYIAEEIATDHIEGLLTRREAFRRLALLGVGATAAGALISACGTGNKPVAAPAPANSGAPPPGMDN VVVTEPITWRGPNGTLQGAWATAAEPRGTVLVIHENKGLNDWVRSVAGRLAGVGYSSLAIDLLSEEGGAS AFKDPAEATGTLGRIAPERFIADLKSGVDEILRRVPGKPAGAVGFCFGGGLVWQLLAAGEPRLAAAAPFY GPLPDNPDFSRSKAAVLAFYGELDERVTASKDQAADALRRGGLLHEIAVEPGADHAFFNDSGPRYNASAA VDAWQRLLGWLGQHIG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3265c | - | - | 100% (297) | hypothetical protein MAB_3265c |
| M. abscessus ATCC 19977 | MAB_3183c | - | 7e-14 | 28.09% (235) | dienelactone hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2787 | - | 9e-12 | 28.39% (236) | hypothetical protein Mb2787 |
| M. gilvum PYR-GCK | Mflv_3311 | - | 1e-115 | 65.57% (305) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2765 | - | 9e-12 | 28.39% (236) | hypothetical protein Rv2765 |
| M. leprae Br4923 | MLBr_01444 | - | 4e-10 | 27.31% (216) | putative dienelactone hydrolase |
| M. marinum M | MMAR_3032 | - | 8e-12 | 26.53% (245) | hypothetical protein MMAR_3032 |
| M. avium 104 | MAV_0487 | - | 2e-19 | 32.59% (224) | dienelactone hydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_3558 | - | 1e-102 | 58.39% (310) | carboxymethylenebutenolidase |
| M. thermoresistible (build 8) | TH_0693 | - | 1e-10 | 29.13% (230) | PROBABLE ALANINE RICH HYDROLASE |
| M. ulcerans Agy99 | MUL_2272 | - | 1e-11 | 26.41% (231) | hypothetical protein MUL_2272 |
| M. vanbaalenii PYR-1 | Mvan_3034 | - | 1e-112 | 63.52% (318) | dienelactone hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3311|M.gilvum_PYR-GCK MTPLQRYIAEEIATDHVDGLMSRREALRRLALLGVGGAAATALIAACGQN
Mvan_3034|M.vanbaalenii_PYR-1 ---MQRYIAEEIATDHVDGLLTRREAMRRLALLGVGGAAATALIAACGQN
MSMEG_3558|M.smegmatis_MC2_155 MTPLQRYIAEEIATDHLDGLMSRREALRRLGLLGLSTAAATAVIAACSER
MAB_3265c|M.abscessus_ATCC_199 MTPLQRYIAEEIATDHIEGLLTRREAFRRLALLGVGATAAGALISACGTG
MMAR_3032|M.marinum_M --MTPTYGNCARVPRTVATRLQLDDAMTTIDID-----------------
MUL_2272|M.ulcerans_Agy99 --------------------------MTTIDID-----------------
MLBr_01444|M.leprae_Br4923 --------------------------MTKIQID-----------------
MAV_0487|M.avium_104 --------------------------MTDIDLTDL---------------
Mb2787|M.bovis_AF2122/97 -----------------------MPKTTDT--------------------
Rv2765|M.tuberculosis_H37Rv -----------------------MPKTTDT--------------------
TH_0693|M.thermoresistible__bu --------------------------------------------------
Mflv_3311|M.gilvum_PYR-GCK QQ--SAETT--AEP--SPTSDTPTSDAPPPGMDAALPTEPVTWAGPKGEL
Mvan_3034|M.vanbaalenii_PYR-1 RQPETAGTS--PEAPGSPASSTADRAAPPPGMDRALPTTPVTWAGPAGEL
MSMEG_3558|M.smegmatis_MC2_155 EQTTTATTENTTDTAGPPTTETQPPSAEPPGMQTALPTAAVTWAGPTGEL
MAB_3265c|M.abscessus_ATCC_199 NKPVAAPAP-------------ANSGAPPPGMDNVVVTEPITWRGPNGTL
MMAR_3032|M.marinum_M ----------------------TPAG--PIDALLGVPTGEGPWPG-----
MUL_2272|M.ulcerans_Agy99 ----------------------TPAG--PIDALLGVPTGEGPWPG-----
MLBr_01444|M.leprae_Br4923 ----------------------APDG--PIDALLSVPPGPEPWPG-----
MAV_0487|M.avium_104 --------------------AAAHAGSQPLRGYLATPSGTGPWPG-----
Mb2787|M.bovis_AF2122/97 ----------------------AATPDGTCAVRLFTPDGPGRWPG-----
Rv2765|M.tuberculosis_H37Rv ----------------------AATPDGTCAVRLFTPDGPGRWPG-----
TH_0693|M.thermoresistible__bu -------------------------------VTLHTPDGAGPWPG-----
* *
Mflv_3311|M.gilvum_PYR-GCK QGAWAQA------------AEPRGGILVIHENKGLNDWTRSVAGRLAGAG
Mvan_3034|M.vanbaalenii_PYR-1 QGAWAPAGASEATGNEGTSGDARGGILVIHENKGLNDWVRSVAGRLAGAG
MSMEG_3558|M.smegmatis_MC2_155 QGAWAEA------------PDARGAVLVIHENKGLTDHIRSVAGRFAGIG
MAB_3265c|M.abscessus_ATCC_199 QGAWATA------------AEPRGTVLVIHENKGLNDWVRSVAGRLAGVG
MMAR_3032|M.marinum_M -------------------------VVVVHDAIGYAPDNEAISERIAAAG
MUL_2272|M.ulcerans_Agy99 -------------------------VVVVHDAIGYAPDNEAISERIAAAG
MLBr_01444|M.leprae_Br4923 -------------------------VVVIHDAIGYEPDKESTNNHIAMAG
MAV_0487|M.avium_104 -------------------------VVLIHEVFGIDDVMRRHTDRLAGLG
Mb2787|M.bovis_AF2122/97 -------------------------VVMFPDAGGVRDTFDRMAAKLAGFG
Rv2765|M.tuberculosis_H37Rv -------------------------VVMFPDAGGVRDTFDRMAAKLAGFG
TH_0693|M.thermoresistible__bu -------------------------VVLFVDAGGTRDLMREMADRLAGYG
:::. : * ::* *
Mflv_3311|M.gilvum_PYR-GCK YSSLAIDLLSERG---------GTATFADPAEATAALGARTPEDMVADLR
Mvan_3034|M.vanbaalenii_PYR-1 YSSLAIDLLSGQG---------GTATFADPAEATAALGQRTPEDMVADLK
MSMEG_3558|M.smegmatis_MC2_155 YSALAIDLLSGQG---------GTGQFADPADATAALSKIPPEEFVANLR
MAB_3265c|M.abscessus_ATCC_199 YSSLAIDLLSEEG---------GASAFKDPAEATGTLGRIAPERFIADLK
MMAR_3032|M.marinum_M YLALTPNMYARGG---------RARCITRVFRELLTKRGRALDDILAARD
MUL_2272|M.ulcerans_Agy99 YLALTPNMYARGG---------RARCITRVFRELLTKRGRALDDILAARD
MLBr_01444|M.leprae_Br4923 YVAITPNLYSRGS---------RARCITRVMRELLTKRGRAFDDILATRD
MAV_0487|M.avium_104 YLTLAVDLFSAGG---------AARCLISTMTAMIRGRGRAFADIAAARD
Mb2787|M.bovis_AF2122/97 YVVLLPDVYYREGDWAPFDMKTAFGDPQERARIMFMIGTLTPDRVTRDAD
Rv2765|M.tuberculosis_H37Rv YVVLLPDVYYREGDWAPFDMKTAFGDPQERARIMFMIGTLTPDRVTRDAD
TH_0693|M.thermoresistible__bu YAVLVPDVYYRHGRWEPFDMRTVFGDPSERARLYRMIRSITPDMMETDAR
* : :: . . .
Mflv_3311|M.gilvum_PYR-GCK SGIAEVQRRTPD--KKVAAIGFCMGGGLVWRLLAAGTPELAAAFPFYG--
Mvan_3034|M.vanbaalenii_PYR-1 SGIAEVARRTPG--KKVAAIGFCMGGGLVWRLLAAGSPELAAAFPFYG--
MSMEG_3558|M.smegmatis_MC2_155 SGIDELSRRAPD--RKLAAVGFCMGGGLVWRLLAAGTPQLAAAVPFYG--
MAB_3265c|M.abscessus_ATCC_199 SGVDEILRRVPG--KPAGAVGFCFGGGLVWQLLAAGEPRLAAAAPFYG--
MMAR_3032|M.marinum_M HLLAMAECSG-----QVGIAGFCMGGQFALILSPRG---FGASAPFYGT-
MUL_2272|M.ulcerans_Agy99 HLLAMAECSG-----QVGIAGFCMGGQFALILSPRG---FGASAPFYGT-
MLBr_01444|M.leprae_Br4923 YLLAMPKCSG-----RVGIAGFCMGGRFALVMSPKG---FDASAPFYGT-
MAV_0487|M.avium_104 YLAGSADCTG-----KVGVIGFCMGGGFALLTANTG---YDAAAVNYG--
Mb2787|M.bovis_AF2122/97 ALLNYLASRPEVIGDRFGVCGYCMGGRMSVVVAGRLPDRVAAAAAFHPGG
Rv2765|M.tuberculosis_H37Rv ALLNYLASRPEVIGDRFGVCGYCMGGRMSVVVAGRLPDRVAAAAAFHPGG
TH_0693|M.thermoresistible__bu AFFDFLQSRPEVKGDRFGVFGYCMGGRMSVTVAGRVPDRVAAAASFHAAG
. *:*:** : *: :
Mflv_3311|M.gilvum_PYR-GCK ---PTPEAPDFAGSRDVAVLAFYGELDQ--RVNATEPDARAALEKAGLVH
Mvan_3034|M.vanbaalenii_PYR-1 ---PTPDNPDFAASKDVAVLGFYGELDQ--RVNATEPVAAAALQKAGLVH
MSMEG_3558|M.smegmatis_MC2_155 ---PTPDDPDFAGSKDVAVLAFYGALDQ--RVNATEPVARAALEKAGLVH
MAB_3265c|M.abscessus_ATCC_199 ---PLPDNPDFSRSK-AAVLAFYGELDE--RVTASKDQAADALRRGGLLH
MMAR_3032|M.marinum_M ---PLPRHLSETLDGACPIVASFGNRDP--LGLGAPSRLREVTQAKQIPA
MUL_2272|M.ulcerans_Agy99 ---PLPRHLSETLDGACPIVASFGNRDP--LGLGAPSRLREVTQAKQIPA
MLBr_01444|M.leprae_Br4923 ---PLPRNLSETLNGACPIVASFGGRDP--LGIGAPKRLRQATQTRHITT
MAV_0487|M.avium_104 ---QLPRHLDTALAGACPIVGSYGGRDP--SLRGATRKLNEALTKAGIEH
Mb2787|M.bovis_AF2122/97 LVANSPDSPHLLADRISATVYIGGAENDPSFTADHAEKLDKAFSAAGVPH
Rv2765|M.tuberculosis_H37Rv LVANSPDSPHLLADRISATVYIGGAENDPSFTADHAEKLDKAFSAAGVPH
TH_0693|M.thermoresistible__bu LVTDDPTSPHLLAERIKATVYVAGAQDDDGFTPAHAETLGKALTDAGVEH
* . : * : . :
Mflv_3311|M.gilvum_PYR-GCK EIVIEPGANHAFFN--------------DTGDRYDPAAAADAWERTLAWL
Mvan_3034|M.vanbaalenii_PYR-1 ELVTEPGANHAFFN--------------DTGDRYDPAAAADAWSRTLDWL
MSMEG_3558|M.smegmatis_MC2_155 ELVTEPGANHAFFN--------------DTGDRYDPTAAADAWRRIQEWF
MAB_3265c|M.abscessus_ATCC_199 EIAVEPGADHAFFN--------------DSGPRYNASAAVDAWQRLLGWL
MMAR_3032|M.marinum_M DIKGYPGAGHSFANKLPR-----QPLLRITGFGYNEAATEDAWGRVFAFF
MUL_2272|M.ulcerans_Agy99 DIEGYPGAGHSFANKLPR-----QPLLRITGFGYNEAATEDAWGRVFAFF
MLBr_01444|M.leprae_Br4923 DIKVYPDAGHSFANKLPG-----QPLMRITGFGYNQAATEDAWSRVFAFF
MAV_0487|M.avium_104 DVKEYPAASHAFLNDDEAGPRILRPLLRVAGIGPEPDSAQDAWNRIAAFF
Mb2787|M.bovis_AF2122/97 RIECYP-AAHGFAVP--------------DNPSYDAAADERHWAAMTETF
Rv2765|M.tuberculosis_H37Rv RIECYP-AAHGFAVP--------------DNPSYDAAADERHWAAMTETF
TH_0693|M.thermoresistible__bu TIEFYP-AGHGFAVP--------------DNLPYDEQAAERHWDALRALF
: * * *.* . : : * :
Mflv_3311|M.gilvum_PYR-GCK TAHVG------
Mvan_3034|M.vanbaalenii_PYR-1 AAHVG------
MSMEG_3558|M.smegmatis_MC2_155 TAHLA------
MAB_3265c|M.abscessus_ATCC_199 GQHIG------
MMAR_3032|M.marinum_M GEHLAAGTSRG
MUL_2272|M.ulcerans_Agy99 GEHLAAGTSGN
MLBr_01444|M.leprae_Br4923 DKHLRTD----
MAV_0487|M.avium_104 ATHLH------
Mb2787|M.bovis_AF2122/97 GAALN------
Rv2765|M.tuberculosis_H37Rv GAALN------
TH_0693|M.thermoresistible__bu DRELSG-----
: