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M. vanbaalenii PYR-1 Mvan_4008 (-)

annotation: AMP-dependent synthetase and ligase
coordinates: 4285723 - 4288854
length: 1043

MITGITLSDALARHAAVRPHACALADPRRHTTFGELDERVTRLASALAARGVRSGDRVAVLGLNSIELVE
SWLAAHRLGAIAVPVNFRLAAGEIGYVLSDSAATAIVVDVALESMVVQVRQQVPALHTVVTIGGNLEQTI
AAADPDLPQCAVADDAPAFIMYTSGTTGFPKGAVLTHRNLYLHAFSSIATLGHRSDDDCWMAVAPLFHTA
GVSGMLPMFLTGGKTVIPPSGGFDPDATIAAVVDEQVTSCWMTPAQWQSVCALPGLAAHDLSRLRRVWWG
AAPASTTLLRTMIDTFTGAEIIAAFGQTECSPITCLLRGEDAIAKIGSVGTPMLNVEVRVVDDEMNDVDR
GEVGEIVYLGPLVMKEYWNKAAETAEAFRGGWFHSGDLVRQDADGYFYVVDRKKDMIISGGENIYSAEVE
NVVATHPLVAEVAVIGVPHPKWGETPVAVIVPREPTDPPTDAEIEAHCRAQLASYKRPKYVTLVDVLPRN
AAGKVLKGRLRDEHATLISYSAGPTDAALLDETIGTNFERTVSRYPDNEALVDVPSGRRWTYAELNAEID
SLARALMAIGIEKGDRVGIWAPNCPEWTMLQYATAKIGAILVTINPAYRTHELAYVLRHSAVRLLVSATE
FKTSDYRAMVAEVRPELPGLAEVLFLATEDWARLGERADLVSEDELRCRVRSLTPGDAINIQYTSGTTGS
PKGATLSHRNILNNGYFVTDLIDFGPGDRLCIPVPFYHCFGMVMGNLGCTTHGATMVIPAAGFDPAATLA
AIEKEHCTAVYGVPTMFIAMLGHPDLADCDVTSLRTGIMAGSPCPVEVMKRCVNELKMSEVGIAYGMTET
SPVSCQTRIEDDLDRRTATVGRAHPHVEIKIVDPDTGEIVKRGTAGEFCTRGYSVMLGYWGDEDRTREAV
DADGWMHTGDLAVMRDDGYCMIVGRIKDMVIRGGENVYPREIEEFLHTHPDIDDVQVIGVPDERYGEEIC
AWIKVRAGAAPLDAHAVREFAAGKLAHYKIPRYVHMTDDFPMTVTGKVRKIDMRAETVRILGL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_4008--100% (1043)AMP-dependent synthetase and ligase
M. vanbaalenii PYR-1Mvan_1563-0.075.86% (526) acyl-CoA synthetase
M. vanbaalenii PYR-1Mvan_0131-e-13751.16% (516) acyl-CoA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2533cfadD350.059.25% (535) AMP-binding domain protein
M. gilvum PYR-GCKMflv_4867-0.073.08% (535) acyl-CoA synthetase
M. tuberculosis H37RvRv2505cfadD350.059.25% (535) AMP-binding domain protein
M. leprae Br4923MLBr_02546fadD29e-4728.49% (509) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_4377c-0.069.16% (535) AMP-binding domain protein
M. marinum MMMAR_3852fadD350.061.12% (535) fatty-acid-CoA ligase FadD35
M. avium 104MAV_5018-1e-12851.20% (498) acyl-CoA synthetase
M. smegmatis MC2 155MSMEG_5649-0.074.21% (535) acyl-CoA synthetase
M. thermoresistible (build 8)TH_2878-1e-13852.52% (516) PUTATIVE AMP-binding enzyme, putative
M. ulcerans Agy99MUL_4126fadD38e-7936.83% (524) acyl-CoA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       MITGITLSDALARHAAVRPHACALADPRRHTTFGELDERVTRLASALAAR
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       GVRSGDRVAVLGLNSIELVESWLAAHRLGAIAVPVNFRLAAGEIGYVLSD
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       SAATAIVVDVALESMVVQVRQQVPALHTVVTIGGNLEQTIAAADPDLPQC
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       AVADDAPAFIMYTSGTTGFPKGAVLTHRNLYLHAFSSIATLGHRSDDDCW
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       MAVAPLFHTAGVSGMLPMFLTGGKTVIPPSGGFDPDATIAAVVDEQVTSC
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       WMTPAQWQSVCALPGLAAHDLSRLRRVWWGAAPASTTLLRTMIDTFTGAE
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       IIAAFGQTECSPITCLLRGEDAIAKIGSVGTPMLNVEVRVVDDEMNDVDR
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       GEVGEIVYLGPLVMKEYWNKAAETAEAFRGGWFHSGDLVRQDADGYFYVV
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       DRKKDMIISGGENIYSAEVENVVATHPLVAEVAVIGVPHPKWGETPVAVI
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           ----------------------------------------------MAAA
Rv2505c|M.tuberculosis_H37Rv        ----------------------------------------------MAAA
MMAR_3852|M.marinum_M               ----------------------------------------------MATT
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       VPREPTDPPTDAEIEAHCRAQLASYKRPKYVTLVDVLPRNAAGKVLKGRL
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MAV_5018|M.avium_104                -------------------------------------------------M
TH_2878|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          ----------------------------MTKLRHYLERGAAEVHYLRSIF
                                                                                      

Mb2533c|M.bovis_AF2122/97           EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRF
Rv2505c|M.tuberculosis_H37Rv        EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRF
MMAR_3852|M.marinum_M               AAADQNQLSYDRGPIAPALLEMTIGANLAATASQCESRDALVDVRSGRRW
Mflv_4867|M.gilvum_PYR-GCK          -----MTGSYDAGPTDVAILEETIGANFARIARTHPGRDALVDVAGGRRW
MAB_4377c|M.abscessus_ATCC_199      ------MKAYDAGATLSPIIEETIGENFERIARAHPDVGALVDVSGDRRW
MSMEG_5649|M.smegmatis_MC2_155      ------MKSYDAGPTGAPVLEETIGANFERIAATYPEHEALVEVATGRRW
Mvan_4008|M.vanbaalenii_PYR-1       RDEHATLISYSAGPTDAALLDETIGTNFERTVSRYPDNEALVDVPSGRRW
MUL_4126|M.ulcerans_Agy99           ----------------MTSDPRTVPTALDRLVRRLPNHDALVTD--ERSF
MAV_5018|M.avium_104                LSLTAQLAHHPTQANEQPYLSRRQNWVNQLERHALMQPNATALRFLGKGL
TH_2878|M.thermoresistible__bu      --------------LQQPYLARRQNWVNHLARHALMQPDATALRFMGQTT
MLBr_02546|M.leprae_Br4923          ESGALGFEPPLTYAAMAVAMRKWGDLAMLPAMPARRSPHRAALIDEEGTL
                                                                             .        

Mb2533c|M.bovis_AF2122/97           NYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAI
Rv2505c|M.tuberculosis_H37Rv        NYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAI
MMAR_3852|M.marinum_M               SYAQLLTDVRQLATGLVRAGIGRGDRVGIWAPNRWEWVLVQYATAEIGAV
Mflv_4867|M.gilvum_PYR-GCK          TYAELDAEIDTVARGLMAIGVERGDRVGIWAPNCPEWVIVQYATAKIGAI
MAB_4377c|M.abscessus_ATCC_199      TYRELDAEINRVARGLMSLGVAAGDRVGIWAPNCAEWVLVQYATAKIGAI
MSMEG_5649|M.smegmatis_MC2_155      TYAELNDEIDATARGLMALGVDKGDRVGIWAPNCAEWIMTQFAAAKVGAI
Mvan_4008|M.vanbaalenii_PYR-1       TYAELNAEIDSLARALMAIGIEKGDRVGIWAPNCPEWTMLQYATAKIGAI
MUL_4126|M.ulcerans_Agy99           TVSELNDEVYRAAAALIELGVKPAARVGIWSPNTWHWVVACLAIHHVGAA
MAV_5018|M.avium_104                TWGELHGRVRALADALSRRGVGFGDRVMVLMLNRPEFMESVLAINMLGAI
TH_2878|M.thermoresistible__bu      TWADLHHRVNRLAGALRRRGVEFGDRVLILMLNRTEFIETMLAANRLGAI
MLBr_02546|M.leprae_Br4923          TYKELDRAAHALANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGAR
                                    .  :*       * .*   *:  .  : :   *   :     .   :** 

Mb2533c|M.bovis_AF2122/97           LVTINPAYRVREVEYALRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDL
Rv2505c|M.tuberculosis_H37Rv        LVTINPAYRVREVEYALRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDL
MMAR_3852|M.marinum_M               LVTINPAYQARELEYALRQSGVAMVIAASGFKGSDYAAILAEVAPGCPEL
Mflv_4867|M.gilvum_PYR-GCK          LVNINPAYRTHELRYVLEQSGVATLISATQFKTSDYVAMVDEVRPDVPAL
MAB_4377c|M.abscessus_ATCC_199      LVNINPAYRTHELAYALNQSGVRTLICAKAFKSSDYVAMASQVMPDAPGL
MSMEG_5649|M.smegmatis_MC2_155      LVNINPAYRTHEVAYVLRQSGVRTLVSASSFKTSDYASMIAEVRPECPDL
Mvan_4008|M.vanbaalenii_PYR-1       LVTINPAYRTHELAYVLRHSAVRLLVSATEFKTSDYRAMVAEVRPELPGL
MUL_4126|M.ulcerans_Agy99           MVPLNTRYTADEAADILARTEAPVLFAMGHFLGSDRVAGLDRKALPALRH
MAV_5018|M.avium_104                AVPLNFRLTAAEIAFLVQDCQARVVITEAVLAP--VATGVRDIESLLDTV
TH_2878|M.thermoresistible__bu      AVPVNFRMTPPEIAFLAKDCEAKVIATEPVLAG--VATAVRDLAPSLSSV
MLBr_02546|M.leprae_Br4923          IILLNSEFSGPQIKEVSEREGAKVIIYDD-----EYTKVVSKAEPALGKL
                                     : :*      :         .  :                         

Mb2533c|M.bovis_AF2122/97           ADVILLESDRWDALAGA--EPDLPA-LQQTAARLDGSDPVNIQYTSGTTA
Rv2505c|M.tuberculosis_H37Rv        ADVILLESDRWDALAGA--EPDLPA-LQQTAARLDGSDPVNIQYTSGTTA
MMAR_3852|M.marinum_M               HDVAFLDGDGWAKLAGS--GADLVA-LQEIATTLSADDPINIQYTSGTTG
Mflv_4867|M.gilvum_PYR-GCK          QRVLFIGTADWDTLRAAGSGVDDAD-LRRRSGALSNRDPINIQYTSGTTG
MAB_4377c|M.abscessus_ATCC_199      RDVVFIGTSDWTELVAGAERVTETA-LRARMSQLSNTDPINIQYTSGTTG
MSMEG_5649|M.smegmatis_MC2_155      LDVVFLDNDDWDRLRAN--QVDDAA-FHERMATLANTDPINIQYTSGTTG
Mvan_4008|M.vanbaalenii_PYR-1       AEVLFLATEDWARLGERADLVSEDE-LRCRVRSLTPGDAINIQYTSGTTG
MUL_4126|M.ulcerans_Agy99           IVRIPIEEPDGTWDEFIETGTDTGA-VTARAAAVSPDDVSDILFTSGTTG
MAV_5018|M.avium_104                VVAG---GSSDDAVLGYDDLIDETG-AAHQPVDIPNDAAALIMYTSGTTG
TH_2878|M.thermoresistible__bu      IVAGAADGSDTPDVLDYEALIAEPG-EDPPPVDIPDDSPALIMYTSGTTG
MLBr_02546|M.leprae_Br4923          RALGVNPDEEEPPGSTDETLAELIARSSSAPAPKVRKRASIIILTSGTTG
                                                                             *  *****.

Mb2533c|M.bovis_AF2122/97           YPKGVTLSHRNILNNGYLVGELLGYTAQ-DRICIPVPFYHCFGMVMGNLA
Rv2505c|M.tuberculosis_H37Rv        YPKGVTLSHRNILNNGYLVGELLGYTAQ-DRICIPVPFYHCFGMVMGNLA
MMAR_3852|M.marinum_M               FPKGVTLSHRNILNNGYLVGELLEYTAE-DRICIPVPFYHCFGMVMGNLA
Mflv_4867|M.gilvum_PYR-GCK          FPKGATLSHRNILNNGFFVTEQIRLQPG-DRLCIPVPFYHCFGMVMGNLG
MAB_4377c|M.abscessus_ATCC_199      YPKGATLSHRNVLNNGFFVAESIQLQAG-DRLCIPVPFYHCFGMVMGNLG
MSMEG_5649|M.smegmatis_MC2_155      FPKGATLSHRNILNNGFFVTELIALGPD-DRLCIVPPFYHCFGMVMGTLG
Mvan_4008|M.vanbaalenii_PYR-1       SPKGATLSHRNILNNGYFVTDLIDFGPG-DRLCIPVPFYHCFGMVMGNLG
MUL_4126|M.ulcerans_Agy99           RSKGVLCAHRQSLSASASWAANGKITAD-DRHLCINPFFHNFGYKAGILA
MAV_5018|M.avium_104                RPKGAVLTHTNLTGQTMTGLYTNGADINNDVGFIGVPFFHIAGIG-NMLT
TH_2878|M.thermoresistible__bu      NPKGAVLTHSNLTGQAMTNLFTIGVDLANDVGFIGVPLFHIAGIAGNVLS
MLBr_02546|M.leprae_Br4923          TPKGANRNTPASLAPLGGILSKVPFRAH-EVTLLPAPMFHALGYLHATLA
                                     .**.                        :      *::*  *     * 

Mb2533c|M.bovis_AF2122/97           ATSHGA-AMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPD--
Rv2505c|M.tuberculosis_H37Rv        ATSHGA-AMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPD--
MMAR_3852|M.marinum_M               ATSHGA-CMVIPAPGFDPAATLRAVQAERCTSLYGVPTMFIAELGLAD--
Mflv_4867|M.gilvum_PYR-GCK          CTTHGA-TIVIPAPAFDPGLTLRAIETERCTAVYGVPTMFIAMQNHPD--
MAB_4377c|M.abscessus_ATCC_199      CTTHGA-TIVMPAPGFDPGRTLEAIERERCVGVYGVPTMFIAMLADPG--
MSMEG_5649|M.smegmatis_MC2_155      AVSHGT-TIVIPAPGFDPGITLSAVESEKCTGLYGVPTMFIAMLGHPD--
Mvan_4008|M.vanbaalenii_PYR-1       CTTHGA-TMVIPAAGFDPAATLAAIEKEHCTAVYGVPTMFIAMLGHPD--
MUL_4126|M.ulcerans_Agy99           CLQTG--ATLFPHLTFDPLRTLQAIERHRITVLPGPPTIYQTLLDHPA--
MAV_5018|M.avium_104                GLLLGIPTVIYPLGAFEPGQLLDVLAAEKVTGIFLVPAQWQAVCAEQR--
TH_2878|M.thermoresistible__bu      GLTLGLPTVLYPLGAFDPGGLLDVLEAEKVTGIFLVPAQWQAVCAEQR--
MLBr_02546|M.leprae_Br4923          MFLGST---LVLRRRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLENL
                                        .    :     *.*   *  :  .: . :   *.            

Mb2533c|M.bovis_AF2122/97           FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVST
Rv2505c|M.tuberculosis_H37Rv        FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVST
MMAR_3852|M.marinum_M               FATYDLSSLRTGIMAGSTCPVEVMRKVIDQMHMAGISICYGMTETSPVAT
Mflv_4867|M.gilvum_PYR-GCK          FAERDLSTLRTGIMAGAVCPVEVMKRCVEEMHLTEMSIAYGMTETSPVSC
MAB_4377c|M.abscessus_ATCC_199      FAHRDLSTLRTGIMAGSVCPVEVMKRCIDEMHMAGVAIAYGMTETSPVSC
MSMEG_5649|M.smegmatis_MC2_155      FANFDLSSLRTGIMAGSVCPIEVMKRVVADMHMAEVAICYGMTETSPVSC
Mvan_4008|M.vanbaalenii_PYR-1       LADCDVTSLRTGIMAGSPCPVEVMKRCVNELKMSEVGIAYGMTETSPVSC
MUL_4126|M.ulcerans_Agy99           RDDYDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGT
MAV_5018|M.avium_104                ARPRDLK-LRVISWGAAPAPDALLREMSAMFPGTQILAAFGQTEMSPVTC
TH_2878|M.thermoresistible__bu      ARPRDLR-LRALSWGAAPASDTLLQEMTEVFPGTKIFAAFGQTEMSPVTC
MLBr_02546|M.leprae_Br4923          ETKSDLSSLRVVFVSGSQLGAELATRALEELG-PVIYNMYGSTEIAFATI
                                        ::  **    ..:     :  .    :    :   :* **      

Mb2533c|M.bovis_AF2122/97           QTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSV
Rv2505c|M.tuberculosis_H37Rv        QTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSV
MMAR_3852|M.marinum_M               QTRSNDSLQRRVTTVGRVGPHLEIKVVDPATGRIVPRGTAGEFCTRGYSV
Mflv_4867|M.gilvum_PYR-GCK          QTLIDDDLERRTSTIGRVHPHVEIKIVDPETGEIVERGTPGEFCTRGYSV
MAB_4377c|M.abscessus_ATCC_199      QTLFDDDLDRRTATVGRAHPHIEIKIVDPNSGETVQRGQSGELCTRGYSV
MSMEG_5649|M.smegmatis_MC2_155      QTLIDDDLDRRTATIGRAHPHVEIKIIDPDTGETVERGQPGEFCTRGYSV
Mvan_4008|M.vanbaalenii_PYR-1       QTRIEDDLDRRTATVGRAHPHVEIKIVDPDTGEIVKRGTAGEFCTRGYSV
MUL_4126|M.ulcerans_Agy99           MCRADDDALTVATTCGRPFADFELRIG-PDTGEVLLRGP---------NV
MAV_5018|M.avium_104                MLLGEDAIR-KRGSVGKVIPTVAARVVDENMN-DVPVGEVGEIVYRAPTL
TH_2878|M.thermoresistible__bu      MLLAEDAVR-KLGSVGKVIPTVAARIVDDTMN-DVPVGEVGEIVYRAPTL
MLBr_02546|M.leprae_Br4923          AG--PKDLQINSATVGPVVKGVKVKILDD-SGKEVPRGQVGRIFVGNAFP
                                         .       : *     .  ::     .  :  *            

Mb2533c|M.bovis_AF2122/97           MAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGE
Rv2505c|M.tuberculosis_H37Rv        MAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGE
MMAR_3852|M.marinum_M               MSGYWKAPERTAEVIDPEGWMHTGDLALMDECGYVQITGRIKDIVVRGGE
Mflv_4867|M.gilvum_PYR-GCK          MLGYWREDEKTAQAIDADGWMHTGDLAVMRPDGYCNIVGRIKDVVIRGGE
MAB_4377c|M.abscessus_ATCC_199      MLGYWNDEAHTREVLDTDGWMHTGDLAVMRDDGYCTIIGRLKDMVIRGGE
MSMEG_5649|M.smegmatis_MC2_155      MLGYWNDDEKTREAVDADGWMHTGDLAVMREDGYCTIVGRIKDMVIRGGE
Mvan_4008|M.vanbaalenii_PYR-1       MLGYWGDEDRTREAVDADGWMHTGDLAVMRDDGYCMIVGRIKDMVIRGGE
MUL_4126|M.ulcerans_Agy99           MLGYLDDPRATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGF
MAV_5018|M.avium_104                MSGYWNNPEATAEAFAG-GWFHSGDLVRMDEDGYVWVVDRKKDMIISGGE
TH_2878|M.thermoresistible__bu      MAGYWNNPQATAEAFAG-GWFHSGDLVRQDEEGYIWVVDRKKDMIISGGE
MLBr_02546|M.leprae_Br4923          FEGYTGG----GGKQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGE
                                    : **              * : :**:      .   : .* .:: : ** 

Mb2533c|M.bovis_AF2122/97           NISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAPELTIE
Rv2505c|M.tuberculosis_H37Rv        NISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAPELTIE
MMAR_3852|M.marinum_M               NISPREIEEFLHSHPDIVDAHVVGVPDERMGEELMAVVKLRAGAPELTTG
Mflv_4867|M.gilvum_PYR-GCK          NIYPREIEEFLYTHPDVEDAHVIGVPDDRYGEEVCAWIRMRPGRTALDAA
MAB_4377c|M.abscessus_ATCC_199      NIYPREIEEFLLTHPDIEDVHVVGVPDEKYGEELCAWVRMRPDRVVIDAV
MSMEG_5649|M.smegmatis_MC2_155      NIYPREIEEFLYTHPDIDDAQVIGVPDERYGEEICAWIRMKPGRPPLDAD
Mvan_4008|M.vanbaalenii_PYR-1       NVYPREIEEFLHTHPDIDDVQVIGVPDERYGEEICAWIKVRAGAAPLDAH
MUL_4126|M.ulcerans_Agy99           NVYPAEVEQVLARLDGVADVAVIGIPDHRLGEVGRAFIVARPG-FNLDEK
MAV_5018|M.avium_104                NIYCAEVENVLASHPDIVEVAVIGRAHEKWGEVPIAVAAVANDN-LALED
TH_2878|M.thermoresistible__bu      NIYCAEVENVLAAHPAVAEVAVVGRPHEKWGEVPVAVVALNPDAELTMAE
MLBr_02546|M.leprae_Br4923          NVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVKKQD-ATIDED
                                    *:   *:*:.:     : :  .:*  . . *    *      .       

Mb2533c|M.bovis_AF2122/97           RLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQQ
Rv2505c|M.tuberculosis_H37Rv        RLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQQ
MMAR_3852|M.marinum_M               LLREYCAGQIAKFKIPRYLRLVDEFPMTVTGKVRKVEMRQQAIEYLRGQH
Mflv_4867|M.gilvum_PYR-GCK          AVREFATDKLAHYKIPRYVHVVDEFPMTVTGKIRKVEMREVSARLLGL--
MAB_4377c|M.abscessus_ATCC_199      AIRAFASGRLAHYKIPRYVHVVESFPMTVTGKVRKIEMRQQTIQIFGLPE
MSMEG_5649|M.smegmatis_MC2_155      KVREFASGKLAHYKIPRYVHVVDEFPMTVTGKIRKVQMREETVALLGLEA
Mvan_4008|M.vanbaalenii_PYR-1       AVREFAAGKLAHYKIPRYVHMTDDFPMTVTGKVRKIDMRAETVRILGL--
MUL_4126|M.ulcerans_Agy99           SVIDYTREHLANFKAPRSVRFVDTLPRNAGGKVVKPQLRELA--------
MAV_5018|M.avium_104                -LDEFLTERLARYKHPKALEIVDALPRNPAGKVLKTELRIRYGGG-----
TH_2878|M.thermoresistible__bu      -LEEFLADRLARYKHPKVLEIVDALPRNPAGKVLKTELRARFAAGPSAEK
MLBr_02546|M.leprae_Br4923          AIKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELRDFEVH------
                                     :  :   ::*.:* *: : . : :* .  **: * ::*           

Mb2533c|M.bovis_AF2122/97           --------------
Rv2505c|M.tuberculosis_H37Rv        --------------
MMAR_3852|M.marinum_M               --------------
Mflv_4867|M.gilvum_PYR-GCK          --------------
MAB_4377c|M.abscessus_ATCC_199      PGRTDEQ-------
MSMEG_5649|M.smegmatis_MC2_155      --------------
Mvan_4008|M.vanbaalenii_PYR-1       --------------
MUL_4126|M.ulcerans_Agy99           --------------
MAV_5018|M.avium_104                --------------
TH_2878|M.thermoresistible__bu      EQSSSGATTSAGSS
MLBr_02546|M.leprae_Br4923          --------------