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MITGITLSDALARHAAVRPHACALADPRRHTTFGELDERVTRLASALAARGVRSGDRVAVLGLNSIELVE SWLAAHRLGAIAVPVNFRLAAGEIGYVLSDSAATAIVVDVALESMVVQVRQQVPALHTVVTIGGNLEQTI AAADPDLPQCAVADDAPAFIMYTSGTTGFPKGAVLTHRNLYLHAFSSIATLGHRSDDDCWMAVAPLFHTA GVSGMLPMFLTGGKTVIPPSGGFDPDATIAAVVDEQVTSCWMTPAQWQSVCALPGLAAHDLSRLRRVWWG AAPASTTLLRTMIDTFTGAEIIAAFGQTECSPITCLLRGEDAIAKIGSVGTPMLNVEVRVVDDEMNDVDR GEVGEIVYLGPLVMKEYWNKAAETAEAFRGGWFHSGDLVRQDADGYFYVVDRKKDMIISGGENIYSAEVE NVVATHPLVAEVAVIGVPHPKWGETPVAVIVPREPTDPPTDAEIEAHCRAQLASYKRPKYVTLVDVLPRN AAGKVLKGRLRDEHATLISYSAGPTDAALLDETIGTNFERTVSRYPDNEALVDVPSGRRWTYAELNAEID SLARALMAIGIEKGDRVGIWAPNCPEWTMLQYATAKIGAILVTINPAYRTHELAYVLRHSAVRLLVSATE FKTSDYRAMVAEVRPELPGLAEVLFLATEDWARLGERADLVSEDELRCRVRSLTPGDAINIQYTSGTTGS PKGATLSHRNILNNGYFVTDLIDFGPGDRLCIPVPFYHCFGMVMGNLGCTTHGATMVIPAAGFDPAATLA AIEKEHCTAVYGVPTMFIAMLGHPDLADCDVTSLRTGIMAGSPCPVEVMKRCVNELKMSEVGIAYGMTET SPVSCQTRIEDDLDRRTATVGRAHPHVEIKIVDPDTGEIVKRGTAGEFCTRGYSVMLGYWGDEDRTREAV DADGWMHTGDLAVMRDDGYCMIVGRIKDMVIRGGENVYPREIEEFLHTHPDIDDVQVIGVPDERYGEEIC AWIKVRAGAAPLDAHAVREFAAGKLAHYKIPRYVHMTDDFPMTVTGKVRKIDMRAETVRILGL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4008 | - | - | 100% (1043) | AMP-dependent synthetase and ligase |
M. vanbaalenii PYR-1 | Mvan_1563 | - | 0.0 | 75.86% (526) | acyl-CoA synthetase |
M. vanbaalenii PYR-1 | Mvan_0131 | - | e-137 | 51.16% (516) | acyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2533c | fadD35 | 0.0 | 59.25% (535) | AMP-binding domain protein |
M. gilvum PYR-GCK | Mflv_4867 | - | 0.0 | 73.08% (535) | acyl-CoA synthetase |
M. tuberculosis H37Rv | Rv2505c | fadD35 | 0.0 | 59.25% (535) | AMP-binding domain protein |
M. leprae Br4923 | MLBr_02546 | fadD2 | 9e-47 | 28.49% (509) | acyl-CoA synthetase |
M. abscessus ATCC 19977 | MAB_4377c | - | 0.0 | 69.16% (535) | AMP-binding domain protein |
M. marinum M | MMAR_3852 | fadD35 | 0.0 | 61.12% (535) | fatty-acid-CoA ligase FadD35 |
M. avium 104 | MAV_5018 | - | 1e-128 | 51.20% (498) | acyl-CoA synthetase |
M. smegmatis MC2 155 | MSMEG_5649 | - | 0.0 | 74.21% (535) | acyl-CoA synthetase |
M. thermoresistible (build 8) | TH_2878 | - | 1e-138 | 52.52% (516) | PUTATIVE AMP-binding enzyme, putative |
M. ulcerans Agy99 | MUL_4126 | fadD3 | 8e-79 | 36.83% (524) | acyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 MITGITLSDALARHAAVRPHACALADPRRHTTFGELDERVTRLASALAAR MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 GVRSGDRVAVLGLNSIELVESWLAAHRLGAIAVPVNFRLAAGEIGYVLSD MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 SAATAIVVDVALESMVVQVRQQVPALHTVVTIGGNLEQTIAAADPDLPQC MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 AVADDAPAFIMYTSGTTGFPKGAVLTHRNLYLHAFSSIATLGHRSDDDCW MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 MAVAPLFHTAGVSGMLPMFLTGGKTVIPPSGGFDPDATIAAVVDEQVTSC MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 WMTPAQWQSVCALPGLAAHDLSRLRRVWWGAAPASTTLLRTMIDTFTGAE MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 IIAAFGQTECSPITCLLRGEDAIAKIGSVGTPMLNVEVRVVDDEMNDVDR MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 GEVGEIVYLGPLVMKEYWNKAAETAEAFRGGWFHSGDLVRQDADGYFYVV MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 -------------------------------------------------- Rv2505c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3852|M.marinum_M -------------------------------------------------- Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 DRKKDMIISGGENIYSAEVENVVATHPLVAEVAVIGVPHPKWGETPVAVI MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------- TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 -------------------------------------------------- Mb2533c|M.bovis_AF2122/97 ----------------------------------------------MAAA Rv2505c|M.tuberculosis_H37Rv ----------------------------------------------MAAA MMAR_3852|M.marinum_M ----------------------------------------------MATT Mflv_4867|M.gilvum_PYR-GCK -------------------------------------------------- MAB_4377c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_5649|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4008|M.vanbaalenii_PYR-1 VPREPTDPPTDAEIEAHCRAQLASYKRPKYVTLVDVLPRNAAGKVLKGRL MUL_4126|M.ulcerans_Agy99 -------------------------------------------------- MAV_5018|M.avium_104 -------------------------------------------------M TH_2878|M.thermoresistible__bu -------------------------------------------------- MLBr_02546|M.leprae_Br4923 ----------------------------MTKLRHYLERGAAEVHYLRSIF Mb2533c|M.bovis_AF2122/97 EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRF Rv2505c|M.tuberculosis_H37Rv EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRF MMAR_3852|M.marinum_M AAADQNQLSYDRGPIAPALLEMTIGANLAATASQCESRDALVDVRSGRRW Mflv_4867|M.gilvum_PYR-GCK -----MTGSYDAGPTDVAILEETIGANFARIARTHPGRDALVDVAGGRRW MAB_4377c|M.abscessus_ATCC_199 ------MKAYDAGATLSPIIEETIGENFERIARAHPDVGALVDVSGDRRW MSMEG_5649|M.smegmatis_MC2_155 ------MKSYDAGPTGAPVLEETIGANFERIAATYPEHEALVEVATGRRW Mvan_4008|M.vanbaalenii_PYR-1 RDEHATLISYSAGPTDAALLDETIGTNFERTVSRYPDNEALVDVPSGRRW MUL_4126|M.ulcerans_Agy99 ----------------MTSDPRTVPTALDRLVRRLPNHDALVTD--ERSF MAV_5018|M.avium_104 LSLTAQLAHHPTQANEQPYLSRRQNWVNQLERHALMQPNATALRFLGKGL TH_2878|M.thermoresistible__bu --------------LQQPYLARRQNWVNHLARHALMQPDATALRFMGQTT MLBr_02546|M.leprae_Br4923 ESGALGFEPPLTYAAMAVAMRKWGDLAMLPAMPARRSPHRAALIDEEGTL . Mb2533c|M.bovis_AF2122/97 NYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAI Rv2505c|M.tuberculosis_H37Rv NYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAI MMAR_3852|M.marinum_M SYAQLLTDVRQLATGLVRAGIGRGDRVGIWAPNRWEWVLVQYATAEIGAV Mflv_4867|M.gilvum_PYR-GCK TYAELDAEIDTVARGLMAIGVERGDRVGIWAPNCPEWVIVQYATAKIGAI MAB_4377c|M.abscessus_ATCC_199 TYRELDAEINRVARGLMSLGVAAGDRVGIWAPNCAEWVLVQYATAKIGAI MSMEG_5649|M.smegmatis_MC2_155 TYAELNDEIDATARGLMALGVDKGDRVGIWAPNCAEWIMTQFAAAKVGAI Mvan_4008|M.vanbaalenii_PYR-1 TYAELNAEIDSLARALMAIGIEKGDRVGIWAPNCPEWTMLQYATAKIGAI MUL_4126|M.ulcerans_Agy99 TVSELNDEVYRAAAALIELGVKPAARVGIWSPNTWHWVVACLAIHHVGAA MAV_5018|M.avium_104 TWGELHGRVRALADALSRRGVGFGDRVMVLMLNRPEFMESVLAINMLGAI TH_2878|M.thermoresistible__bu TWADLHHRVNRLAGALRRRGVEFGDRVLILMLNRTEFIETMLAANRLGAI MLBr_02546|M.leprae_Br4923 TYKELDRAAHALANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGAR . :* * .* *: . : : * : . :** Mb2533c|M.bovis_AF2122/97 LVTINPAYRVREVEYALRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDL Rv2505c|M.tuberculosis_H37Rv LVTINPAYRVREVEYALRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDL MMAR_3852|M.marinum_M LVTINPAYQARELEYALRQSGVAMVIAASGFKGSDYAAILAEVAPGCPEL Mflv_4867|M.gilvum_PYR-GCK LVNINPAYRTHELRYVLEQSGVATLISATQFKTSDYVAMVDEVRPDVPAL MAB_4377c|M.abscessus_ATCC_199 LVNINPAYRTHELAYALNQSGVRTLICAKAFKSSDYVAMASQVMPDAPGL MSMEG_5649|M.smegmatis_MC2_155 LVNINPAYRTHEVAYVLRQSGVRTLVSASSFKTSDYASMIAEVRPECPDL Mvan_4008|M.vanbaalenii_PYR-1 LVTINPAYRTHELAYVLRHSAVRLLVSATEFKTSDYRAMVAEVRPELPGL MUL_4126|M.ulcerans_Agy99 MVPLNTRYTADEAADILARTEAPVLFAMGHFLGSDRVAGLDRKALPALRH MAV_5018|M.avium_104 AVPLNFRLTAAEIAFLVQDCQARVVITEAVLAP--VATGVRDIESLLDTV TH_2878|M.thermoresistible__bu AVPVNFRMTPPEIAFLAKDCEAKVIATEPVLAG--VATAVRDLAPSLSSV MLBr_02546|M.leprae_Br4923 IILLNSEFSGPQIKEVSEREGAKVIIYDD-----EYTKVVSKAEPALGKL : :* : . : Mb2533c|M.bovis_AF2122/97 ADVILLESDRWDALAGA--EPDLPA-LQQTAARLDGSDPVNIQYTSGTTA Rv2505c|M.tuberculosis_H37Rv ADVILLESDRWDALAGA--EPDLPA-LQQTAARLDGSDPVNIQYTSGTTA MMAR_3852|M.marinum_M HDVAFLDGDGWAKLAGS--GADLVA-LQEIATTLSADDPINIQYTSGTTG Mflv_4867|M.gilvum_PYR-GCK QRVLFIGTADWDTLRAAGSGVDDAD-LRRRSGALSNRDPINIQYTSGTTG MAB_4377c|M.abscessus_ATCC_199 RDVVFIGTSDWTELVAGAERVTETA-LRARMSQLSNTDPINIQYTSGTTG MSMEG_5649|M.smegmatis_MC2_155 LDVVFLDNDDWDRLRAN--QVDDAA-FHERMATLANTDPINIQYTSGTTG Mvan_4008|M.vanbaalenii_PYR-1 AEVLFLATEDWARLGERADLVSEDE-LRCRVRSLTPGDAINIQYTSGTTG MUL_4126|M.ulcerans_Agy99 IVRIPIEEPDGTWDEFIETGTDTGA-VTARAAAVSPDDVSDILFTSGTTG MAV_5018|M.avium_104 VVAG---GSSDDAVLGYDDLIDETG-AAHQPVDIPNDAAALIMYTSGTTG TH_2878|M.thermoresistible__bu IVAGAADGSDTPDVLDYEALIAEPG-EDPPPVDIPDDSPALIMYTSGTTG MLBr_02546|M.leprae_Br4923 RALGVNPDEEEPPGSTDETLAELIARSSSAPAPKVRKRASIIILTSGTTG * *****. Mb2533c|M.bovis_AF2122/97 YPKGVTLSHRNILNNGYLVGELLGYTAQ-DRICIPVPFYHCFGMVMGNLA Rv2505c|M.tuberculosis_H37Rv YPKGVTLSHRNILNNGYLVGELLGYTAQ-DRICIPVPFYHCFGMVMGNLA MMAR_3852|M.marinum_M FPKGVTLSHRNILNNGYLVGELLEYTAE-DRICIPVPFYHCFGMVMGNLA Mflv_4867|M.gilvum_PYR-GCK FPKGATLSHRNILNNGFFVTEQIRLQPG-DRLCIPVPFYHCFGMVMGNLG MAB_4377c|M.abscessus_ATCC_199 YPKGATLSHRNVLNNGFFVAESIQLQAG-DRLCIPVPFYHCFGMVMGNLG MSMEG_5649|M.smegmatis_MC2_155 FPKGATLSHRNILNNGFFVTELIALGPD-DRLCIVPPFYHCFGMVMGTLG Mvan_4008|M.vanbaalenii_PYR-1 SPKGATLSHRNILNNGYFVTDLIDFGPG-DRLCIPVPFYHCFGMVMGNLG MUL_4126|M.ulcerans_Agy99 RSKGVLCAHRQSLSASASWAANGKITAD-DRHLCINPFFHNFGYKAGILA MAV_5018|M.avium_104 RPKGAVLTHTNLTGQTMTGLYTNGADINNDVGFIGVPFFHIAGIG-NMLT TH_2878|M.thermoresistible__bu NPKGAVLTHSNLTGQAMTNLFTIGVDLANDVGFIGVPLFHIAGIAGNVLS MLBr_02546|M.leprae_Br4923 TPKGANRNTPASLAPLGGILSKVPFRAH-EVTLLPAPMFHALGYLHATLA .**. : *::* * * Mb2533c|M.bovis_AF2122/97 ATSHGA-AMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPD-- Rv2505c|M.tuberculosis_H37Rv ATSHGA-AMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPD-- MMAR_3852|M.marinum_M ATSHGA-CMVIPAPGFDPAATLRAVQAERCTSLYGVPTMFIAELGLAD-- Mflv_4867|M.gilvum_PYR-GCK CTTHGA-TIVIPAPAFDPGLTLRAIETERCTAVYGVPTMFIAMQNHPD-- MAB_4377c|M.abscessus_ATCC_199 CTTHGA-TIVMPAPGFDPGRTLEAIERERCVGVYGVPTMFIAMLADPG-- MSMEG_5649|M.smegmatis_MC2_155 AVSHGT-TIVIPAPGFDPGITLSAVESEKCTGLYGVPTMFIAMLGHPD-- Mvan_4008|M.vanbaalenii_PYR-1 CTTHGA-TMVIPAAGFDPAATLAAIEKEHCTAVYGVPTMFIAMLGHPD-- MUL_4126|M.ulcerans_Agy99 CLQTG--ATLFPHLTFDPLRTLQAIERHRITVLPGPPTIYQTLLDHPA-- MAV_5018|M.avium_104 GLLLGIPTVIYPLGAFEPGQLLDVLAAEKVTGIFLVPAQWQAVCAEQR-- TH_2878|M.thermoresistible__bu GLTLGLPTVLYPLGAFDPGGLLDVLEAEKVTGIFLVPAQWQAVCAEQR-- MLBr_02546|M.leprae_Br4923 MFLGST---LVLRRRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLENL . : *.* * : .: . : *. Mb2533c|M.bovis_AF2122/97 FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVST Rv2505c|M.tuberculosis_H37Rv FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVST MMAR_3852|M.marinum_M FATYDLSSLRTGIMAGSTCPVEVMRKVIDQMHMAGISICYGMTETSPVAT Mflv_4867|M.gilvum_PYR-GCK FAERDLSTLRTGIMAGAVCPVEVMKRCVEEMHLTEMSIAYGMTETSPVSC MAB_4377c|M.abscessus_ATCC_199 FAHRDLSTLRTGIMAGSVCPVEVMKRCIDEMHMAGVAIAYGMTETSPVSC MSMEG_5649|M.smegmatis_MC2_155 FANFDLSSLRTGIMAGSVCPIEVMKRVVADMHMAEVAICYGMTETSPVSC Mvan_4008|M.vanbaalenii_PYR-1 LADCDVTSLRTGIMAGSPCPVEVMKRCVNELKMSEVGIAYGMTETSPVSC MUL_4126|M.ulcerans_Agy99 RDDYDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGT MAV_5018|M.avium_104 ARPRDLK-LRVISWGAAPAPDALLREMSAMFPGTQILAAFGQTEMSPVTC TH_2878|M.thermoresistible__bu ARPRDLR-LRALSWGAAPASDTLLQEMTEVFPGTKIFAAFGQTEMSPVTC MLBr_02546|M.leprae_Br4923 ETKSDLSSLRVVFVSGSQLGAELATRALEELG-PVIYNMYGSTEIAFATI :: ** ..: : . : : :* ** Mb2533c|M.bovis_AF2122/97 QTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSV Rv2505c|M.tuberculosis_H37Rv QTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSV MMAR_3852|M.marinum_M QTRSNDSLQRRVTTVGRVGPHLEIKVVDPATGRIVPRGTAGEFCTRGYSV Mflv_4867|M.gilvum_PYR-GCK QTLIDDDLERRTSTIGRVHPHVEIKIVDPETGEIVERGTPGEFCTRGYSV MAB_4377c|M.abscessus_ATCC_199 QTLFDDDLDRRTATVGRAHPHIEIKIVDPNSGETVQRGQSGELCTRGYSV MSMEG_5649|M.smegmatis_MC2_155 QTLIDDDLDRRTATIGRAHPHVEIKIIDPDTGETVERGQPGEFCTRGYSV Mvan_4008|M.vanbaalenii_PYR-1 QTRIEDDLDRRTATVGRAHPHVEIKIVDPDTGEIVKRGTAGEFCTRGYSV MUL_4126|M.ulcerans_Agy99 MCRADDDALTVATTCGRPFADFELRIG-PDTGEVLLRGP---------NV MAV_5018|M.avium_104 MLLGEDAIR-KRGSVGKVIPTVAARVVDENMN-DVPVGEVGEIVYRAPTL TH_2878|M.thermoresistible__bu MLLAEDAVR-KLGSVGKVIPTVAARIVDDTMN-DVPVGEVGEIVYRAPTL MLBr_02546|M.leprae_Br4923 AG--PKDLQINSATVGPVVKGVKVKILDD-SGKEVPRGQVGRIFVGNAFP . : * . :: . : * Mb2533c|M.bovis_AF2122/97 MAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGE Rv2505c|M.tuberculosis_H37Rv MAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGE MMAR_3852|M.marinum_M MSGYWKAPERTAEVIDPEGWMHTGDLALMDECGYVQITGRIKDIVVRGGE Mflv_4867|M.gilvum_PYR-GCK MLGYWREDEKTAQAIDADGWMHTGDLAVMRPDGYCNIVGRIKDVVIRGGE MAB_4377c|M.abscessus_ATCC_199 MLGYWNDEAHTREVLDTDGWMHTGDLAVMRDDGYCTIIGRLKDMVIRGGE MSMEG_5649|M.smegmatis_MC2_155 MLGYWNDDEKTREAVDADGWMHTGDLAVMREDGYCTIVGRIKDMVIRGGE Mvan_4008|M.vanbaalenii_PYR-1 MLGYWGDEDRTREAVDADGWMHTGDLAVMRDDGYCMIVGRIKDMVIRGGE MUL_4126|M.ulcerans_Agy99 MLGYLDDPRATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGF MAV_5018|M.avium_104 MSGYWNNPEATAEAFAG-GWFHSGDLVRMDEDGYVWVVDRKKDMIISGGE TH_2878|M.thermoresistible__bu MAGYWNNPQATAEAFAG-GWFHSGDLVRQDEEGYIWVVDRKKDMIISGGE MLBr_02546|M.leprae_Br4923 FEGYTGG----GGKQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGE : ** * : :**: . : .* .:: : ** Mb2533c|M.bovis_AF2122/97 NISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAPELTIE Rv2505c|M.tuberculosis_H37Rv NISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAPELTIE MMAR_3852|M.marinum_M NISPREIEEFLHSHPDIVDAHVVGVPDERMGEELMAVVKLRAGAPELTTG Mflv_4867|M.gilvum_PYR-GCK NIYPREIEEFLYTHPDVEDAHVIGVPDDRYGEEVCAWIRMRPGRTALDAA MAB_4377c|M.abscessus_ATCC_199 NIYPREIEEFLLTHPDIEDVHVVGVPDEKYGEELCAWVRMRPDRVVIDAV MSMEG_5649|M.smegmatis_MC2_155 NIYPREIEEFLYTHPDIDDAQVIGVPDERYGEEICAWIRMKPGRPPLDAD Mvan_4008|M.vanbaalenii_PYR-1 NVYPREIEEFLHTHPDIDDVQVIGVPDERYGEEICAWIKVRAGAAPLDAH MUL_4126|M.ulcerans_Agy99 NVYPAEVEQVLARLDGVADVAVIGIPDHRLGEVGRAFIVARPG-FNLDEK MAV_5018|M.avium_104 NIYCAEVENVLASHPDIVEVAVIGRAHEKWGEVPIAVAAVANDN-LALED TH_2878|M.thermoresistible__bu NIYCAEVENVLAAHPAVAEVAVVGRPHEKWGEVPVAVVALNPDAELTMAE MLBr_02546|M.leprae_Br4923 NVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVKKQD-ATIDED *: *:*:.: : : .:* . . * * . Mb2533c|M.bovis_AF2122/97 RLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQQ Rv2505c|M.tuberculosis_H37Rv RLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQQ MMAR_3852|M.marinum_M LLREYCAGQIAKFKIPRYLRLVDEFPMTVTGKVRKVEMRQQAIEYLRGQH Mflv_4867|M.gilvum_PYR-GCK AVREFATDKLAHYKIPRYVHVVDEFPMTVTGKIRKVEMREVSARLLGL-- MAB_4377c|M.abscessus_ATCC_199 AIRAFASGRLAHYKIPRYVHVVESFPMTVTGKVRKIEMRQQTIQIFGLPE MSMEG_5649|M.smegmatis_MC2_155 KVREFASGKLAHYKIPRYVHVVDEFPMTVTGKIRKVQMREETVALLGLEA Mvan_4008|M.vanbaalenii_PYR-1 AVREFAAGKLAHYKIPRYVHMTDDFPMTVTGKVRKIDMRAETVRILGL-- MUL_4126|M.ulcerans_Agy99 SVIDYTREHLANFKAPRSVRFVDTLPRNAGGKVVKPQLRELA-------- MAV_5018|M.avium_104 -LDEFLTERLARYKHPKALEIVDALPRNPAGKVLKTELRIRYGGG----- TH_2878|M.thermoresistible__bu -LEEFLADRLARYKHPKVLEIVDALPRNPAGKVLKTELRARFAAGPSAEK MLBr_02546|M.leprae_Br4923 AIKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELRDFEVH------ : : ::*.:* *: : . : :* . **: * ::* Mb2533c|M.bovis_AF2122/97 -------------- Rv2505c|M.tuberculosis_H37Rv -------------- MMAR_3852|M.marinum_M -------------- Mflv_4867|M.gilvum_PYR-GCK -------------- MAB_4377c|M.abscessus_ATCC_199 PGRTDEQ------- MSMEG_5649|M.smegmatis_MC2_155 -------------- Mvan_4008|M.vanbaalenii_PYR-1 -------------- MUL_4126|M.ulcerans_Agy99 -------------- MAV_5018|M.avium_104 -------------- TH_2878|M.thermoresistible__bu EQSSSGATTSAGSS MLBr_02546|M.leprae_Br4923 --------------