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M. marinum M MMAR_3852 (fadD35)

annotation: fatty-acid-CoA ligase FadD35
coordinates: 4789326 - 4790969
length: 547

ATTAAADQNQLSYDRGPIAPALLEMTIGANLAATASQCESRDALVDVRSGRRWSYAQLLTDVRQLATGLV
RAGIGRGDRVGIWAPNRWEWVLVQYATAEIGAVLVTINPAYQARELEYALRQSGVAMVIAASGFKGSDYA
AILAEVAPGCPELHDVAFLDGDGWAKLAGSGADLVALQEIATTLSADDPINIQYTSGTTGFPKGVTLSHR
NILNNGYLVGELLEYTAEDRICIPVPFYHCFGMVMGNLAATSHGACMVIPAPGFDPAATLRAVQAERCTS
LYGVPTMFIAELGLADFATYDLSSLRTGIMAGSTCPVEVMRKVIDQMHMAGISICYGMTETSPVATQTRS
NDSLQRRVTTVGRVGPHLEIKVVDPATGRIVPRGTAGEFCTRGYSVMSGYWKAPERTAEVIDPEGWMHTG
DLALMDECGYVQITGRIKDIVVRGGENISPREIEEFLHSHPDIVDAHVVGVPDERMGEELMAVVKLRAGA
PELTTGLLREYCAGQIAKFKIPRYLRLVDEFPMTVTGKVRKVEMRQQAIEYLRGQH*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3852fadD35-100% (547)fatty-acid-CoA ligase FadD35
M. marinum MMMAR_5050fadD35e-7534.17% (515) fatty-acid-CoA ligase FadD3
M. marinum MMMAR_4688fadD3_22e-7335.56% (495) fatty-acid-CoA ligase FadD3_2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2533cfadD350.078.39% (546) AMP-binding domain protein
M. gilvum PYR-GCKMflv_4867-0.061.91% (533) acyl-CoA synthetase
M. tuberculosis H37RvRv2505cfadD350.078.39% (546) AMP-binding domain protein
M. leprae Br4923MLBr_02546fadD23e-4528.74% (515) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_4377c-0.059.40% (532) AMP-binding domain protein
M. avium 104MAV_0600fadD4e-7835.08% (516) acyl-CoA synthetase
M. smegmatis MC2 155MSMEG_5649-0.060.83% (531) acyl-CoA synthetase
M. thermoresistible (build 8)TH_2068fadD32e-8237.28% (523) PROBABLE FATTY-ACID-CoA LIGASE FADD3 (FATTY-ACID-CoA
M. ulcerans Agy99MUL_4126fadD36e-7534.17% (515) acyl-CoA synthetase
M. vanbaalenii PYR-1Mvan_4008-0.061.12% (535) AMP-dependent synthetase and ligase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       MITGITLSDALARHAAVRPHACALADPRRHTTFGELDERVTRLASALAAR
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       GVRSGDRVAVLGLNSIELVESWLAAHRLGAIAVPVNFRLAAGEIGYVLSD
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       SAATAIVVDVALESMVVQVRQQVPALHTVVTIGGNLEQTIAAADPDLPQC
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       AVADDAPAFIMYTSGTTGFPKGAVLTHRNLYLHAFSSIATLGHRSDDDCW
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       MAVAPLFHTAGVSGMLPMFLTGGKTVIPPSGGFDPDATIAAVVDEQVTSC
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       WMTPAQWQSVCALPGLAAHDLSRLRRVWWGAAPASTTLLRTMIDTFTGAE
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       IIAAFGQTECSPITCLLRGEDAIAKIGSVGTPMLNVEVRVVDDEMNDVDR
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       GEVGEIVYLGPLVMKEYWNKAAETAEAFRGGWFHSGDLVRQDADGYFYVV
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3852|M.marinum_M               --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       DRKKDMIISGGENIYSAEVENVVATHPLVAEVAVIGVPHPKWGETPVAVI
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2533c|M.bovis_AF2122/97           ----------------------------------------------MAAA
Rv2505c|M.tuberculosis_H37Rv        ----------------------------------------------MAAA
MMAR_3852|M.marinum_M               ----------------------------------------------MATT
MSMEG_5649|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       VPREPTDPPTDAEIEAHCRAQLASYKRPKYVTLVDVLPRNAAGKVLKGRL
Mflv_4867|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0600|M.avium_104                --------------------------------------------------
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
TH_2068|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------MTKLRHYLERGAAEVHYLRSIFES
                                                                                      

Mb2533c|M.bovis_AF2122/97           EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMV----A
Rv2505c|M.tuberculosis_H37Rv        EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMV----A
MMAR_3852|M.marinum_M               AAADQNQLSYDRGPIAPALLEMTIGANLAATASQCESRDALVDVR----S
MSMEG_5649|M.smegmatis_MC2_155      ------MKSYDAGPTGAPVLEETIGANFERIAATYPEHEALVEVA----T
Mvan_4008|M.vanbaalenii_PYR-1       RDEHATLISYSAGPTDAALLDETIGTNFERTVSRYPDNEALVDVP----S
Mflv_4867|M.gilvum_PYR-GCK          -----MTGSYDAGPTDVAILEETIGANFARIARTHPGRDALVDVA----G
MAB_4377c|M.abscessus_ATCC_199      ------MKAYDAGATLSPIIEETIGENFERIARAHPDVGALVDVS----G
MAV_0600|M.avium_104                ----------------MTTDPRTVPAALDRLARRLPDHDALIT------E
MUL_4126|M.ulcerans_Agy99           ----------------MTSDPRTVPTALDRLVRRLPNHDALVT------D
TH_2068|M.thermoresistible__bu      --------------------MRTIPAVLDRAAERLPDHDALVTAATGGAE
MLBr_02546|M.leprae_Br4923          GALGFEPPLTYAAMAVAMRKWGDLAMLPAMPARRSPHRAALIDEE-----
                                                           :       .       **:        

Mb2533c|M.bovis_AF2122/97           RRRFNYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAE
Rv2505c|M.tuberculosis_H37Rv        RRRFNYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAE
MMAR_3852|M.marinum_M               GRRWSYAQLLTDVRQLATGLVRAGIGRGDRVGIWAPNRWEWVLVQYATAE
MSMEG_5649|M.smegmatis_MC2_155      GRRWTYAELNDEIDATARGLMALGVDKGDRVGIWAPNCAEWIMTQFAAAK
Mvan_4008|M.vanbaalenii_PYR-1       GRRWTYAELNAEIDSLARALMAIGIEKGDRVGIWAPNCPEWTMLQYATAK
Mflv_4867|M.gilvum_PYR-GCK          GRRWTYAELDAEIDTVARGLMAIGVERGDRVGIWAPNCPEWVIVQYATAK
MAB_4377c|M.abscessus_ATCC_199      DRRWTYRELDAEINRVARGLMSLGVAAGDRVGIWAPNCAEWVLVQYATAK
MAV_0600|M.avium_104                DRSFTAAALRDEVHRAAAALIELGVRAGDRVAIWSPNTWHWVVACLAIHH
MUL_4126|M.ulcerans_Agy99           ERSFTVSELNDEVYRAAAALIELGVKPAARVGIWSPNTWHWVVACLAIHH
TH_2068|M.thermoresistible__bu      ARRFSYAELRAEVRRAAAAMIAAGIAPGDRVALWAPNTWHWVVACLATHY
MLBr_02546|M.leprae_Br4923          -GTLTYKELDRAAHALANGLIAKGVRGGDGIAILARNHRWFVIANYGCAR
                                        .   *       * .::  *:  .  :.: : *   : :   .   

Mb2533c|M.bovis_AF2122/97           IGAILVTINPAYRVREVEYALRQSGVAMVIAVASFKDAD-YAAMLAEVGP
Rv2505c|M.tuberculosis_H37Rv        IGAILVTINPAYRVREVEYALRQSGVAMVIAVASFKDAD-YAAMLAEVGP
MMAR_3852|M.marinum_M               IGAVLVTINPAYQARELEYALRQSGVAMVIAASGFKGSD-YAAILAEVAP
MSMEG_5649|M.smegmatis_MC2_155      VGAILVNINPAYRTHEVAYVLRQSGVRTLVSASSFKTSD-YASMIAEVRP
Mvan_4008|M.vanbaalenii_PYR-1       IGAILVTINPAYRTHELAYVLRHSAVRLLVSATEFKTSD-YRAMVAEVRP
Mflv_4867|M.gilvum_PYR-GCK          IGAILVNINPAYRTHELRYVLEQSGVATLISATQFKTSD-YVAMVDEVRP
MAB_4377c|M.abscessus_ATCC_199      IGAILVNINPAYRTHELAYALNQSGVRTLICAKAFKSSD-YVAMASQVMP
MAV_0600|M.avium_104                AGAAMVPLNTRYTAAEAGDILARVGAPVLFGMGRFLGHDRLADLDRAALP
MUL_4126|M.ulcerans_Agy99           VGAAMVPLNTRYTADEAADILARTEAPVLFAMGHFLGSDRVAGLDRKALP
TH_2068|M.thermoresistible__bu      AGAVMVPLNTRYTASEAADVLARTGAPLLVAAGEFLGADKTADLDRDALP
MLBr_02546|M.leprae_Br4923          VGARIILLNSEFSGPQIKEVSEREGAKVIIYDDEY------TKVVSKAEP
                                     ** :: :*. :   :      :  .  :.    :        :   . *

Mb2533c|M.bovis_AF2122/97           RCPDLADVILLESD----RWDAL--AGAEP--DLPALQQTAARLDGSDPV
Rv2505c|M.tuberculosis_H37Rv        RCPDLADVILLESD----RWDAL--AGAEP--DLPALQQTAARLDGSDPV
MMAR_3852|M.marinum_M               GCPELHDVAFLDGD----GWAKL--AGSGA--DLVALQEIATTLSADDPI
MSMEG_5649|M.smegmatis_MC2_155      ECPDLLDVVFLDND----DWDRL--RANQV--DDAAFHERMATLANTDPI
Mvan_4008|M.vanbaalenii_PYR-1       ELPGLAEVLFLATE----DWARLGERADLV--SEDELRCRVRSLTPGDAI
Mflv_4867|M.gilvum_PYR-GCK          DVPALQRVLFIGTA----DWDTLRAAGSGV--DDADLRRRSGALSNRDPI
MAB_4377c|M.abscessus_ATCC_199      DAPGLRDVVFIGTS----DWTELVAGAERV--TETALRARMSQLSNTDPI
MAV_0600|M.avium_104                ALRHIVRIPIETDDPVPGSWDEFIAHG----TDLGAVAERAAAVTSDDVS
MUL_4126|M.ulcerans_Agy99           ALRHIVRIPIEEPD---GTWDEFIETG----TDTGAVTARAAAVSPDDVS
TH_2068|M.thermoresistible__bu      ALRRIVRIPVDKPD---GTWDEFIAGGSMSGAALAEVDARAAAVRPDDVS
MLBr_02546|M.leprae_Br4923          ALGKLRALGVNPDE-----EEPPGSTDETLAELIARSSSAPAPKVRKRAS
                                        :  : .                                        

Mb2533c|M.bovis_AF2122/97           NIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHC
Rv2505c|M.tuberculosis_H37Rv        NIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHC
MMAR_3852|M.marinum_M               NIQYTSGTTGFPKGVTLSHRNILNNGYLVGELLEYTAEDRICIPVPFYHC
MSMEG_5649|M.smegmatis_MC2_155      NIQYTSGTTGFPKGATLSHRNILNNGFFVTELIALGPDDRLCIVPPFYHC
Mvan_4008|M.vanbaalenii_PYR-1       NIQYTSGTTGSPKGATLSHRNILNNGYFVTDLIDFGPGDRLCIPVPFYHC
Mflv_4867|M.gilvum_PYR-GCK          NIQYTSGTTGFPKGATLSHRNILNNGFFVTEQIRLQPGDRLCIPVPFYHC
MAB_4377c|M.abscessus_ATCC_199      NIQYTSGTTGYPKGATLSHRNVLNNGFFVAESIQLQAGDRLCIPVPFYHC
MAV_0600|M.avium_104                DILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHN
MUL_4126|M.ulcerans_Agy99           DILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITADDRHLCINPFFHN
TH_2068|M.thermoresistible__bu      DILFTSGTTGRSKGALCAHRQSLDASAAWAECGRLSSDDRYLCINPFFHN
MLBr_02546|M.leprae_Br4923          IIILTSGTTGTPKGANRNTPASLAPLGGILSKVPFRAHEVTLLPAPMFHA
                                     *  *****. .**.       *             . :      *::* 

Mb2533c|M.bovis_AF2122/97           FGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIA
Rv2505c|M.tuberculosis_H37Rv        FGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIA
MMAR_3852|M.marinum_M               FGMVMGNLAATSHGACMVIPAPGFDPAATLRAVQAERCTSLYGVPTMFIA
MSMEG_5649|M.smegmatis_MC2_155      FGMVMGTLGAVSHGTTIVIPAPGFDPGITLSAVESEKCTGLYGVPTMFIA
Mvan_4008|M.vanbaalenii_PYR-1       FGMVMGNLGCTTHGATMVIPAAGFDPAATLAAIEKEHCTAVYGVPTMFIA
Mflv_4867|M.gilvum_PYR-GCK          FGMVMGNLGCTTHGATIVIPAPAFDPGLTLRAIETERCTAVYGVPTMFIA
MAB_4377c|M.abscessus_ATCC_199      FGMVMGNLGCTTHGATIVMPAPGFDPGRTLEAIERERCVGVYGVPTMFIA
MAV_0600|M.avium_104                FGYKAGILACLQTGAT-LIPHLTFDPLRALQAIEQHRITVLPGPPTIYQT
MUL_4126|M.ulcerans_Agy99           FGYKAGILACLQTGAT-LFPHLTFDPLRTLQAIERHRITVLPGPPTIYQT
TH_2068|M.thermoresistible__bu      FGYKAGILACIQTGAT-LYPQLTFDPEQAMRAVAEHRITVLPGPPTIYQT
MLBr_02546|M.leprae_Br4923          LGYLHATLAMFLGSTLVLRRR--FKPATVLEDIEKHQATAMVVVPVMLSR
                                    :*   . *.    .:  :     *.*  .:  :  .: . :   *.:   

Mb2533c|M.bovis_AF2122/97           ELGLPD--FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGM
Rv2505c|M.tuberculosis_H37Rv        ELGLPD--FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGM
MMAR_3852|M.marinum_M               ELGLAD--FATYDLSSLRTGIMAGSTCPVEVMRKVIDQMHMAGISICYGM
MSMEG_5649|M.smegmatis_MC2_155      MLGHPD--FANFDLSSLRTGIMAGSVCPIEVMKRVVADMHMAEVAICYGM
Mvan_4008|M.vanbaalenii_PYR-1       MLGHPD--LADCDVTSLRTGIMAGSPCPVEVMKRCVNELKMSEVGIAYGM
Mflv_4867|M.gilvum_PYR-GCK          MQNHPD--FAERDLSTLRTGIMAGAVCPVEVMKRCVEEMHLTEMSIAYGM
MAB_4377c|M.abscessus_ATCC_199      MLADPG--FAHRDLSTLRTGIMAGSVCPVEVMKRCIDEMHMAGVAIAYGM
MAV_0600|M.avium_104                LLDHPA--RRDYDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGL
MUL_4126|M.ulcerans_Agy99           LLDHPA--RDDYDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGL
TH_2068|M.thermoresistible__bu      ILDHPK--RGEYDLSSLRFAVTGAAVVPVVLIERMQSELDIDIVLTAYGL
MLBr_02546|M.leprae_Br4923          ILDTLENLETKSDLSSLRVVFVSGSQLGAELATRALEELG-PVIYNMYGS
                                                :: :**  . ..:     :  :    :    :   ** 

Mb2533c|M.bovis_AF2122/97           TETSPVSTQTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGE
Rv2505c|M.tuberculosis_H37Rv        TETSPVSTQTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGE
MMAR_3852|M.marinum_M               TETSPVATQTRSNDSLQRRVTTVGRVGPHLEIKVVDPATGRIVPRGTAGE
MSMEG_5649|M.smegmatis_MC2_155      TETSPVSCQTLIDDDLDRRTATIGRAHPHVEIKIIDPDTGETVERGQPGE
Mvan_4008|M.vanbaalenii_PYR-1       TETSPVSCQTRIEDDLDRRTATVGRAHPHVEIKIVDPDTGEIVKRGTAGE
Mflv_4867|M.gilvum_PYR-GCK          TETSPVSCQTLIDDDLERRTSTIGRVHPHVEIKIVDPETGEIVERGTPGE
MAB_4377c|M.abscessus_ATCC_199      TETSPVSCQTLFDDDLDRRTATVGRAHPHIEIKIVDPNSGETVQRGQSGE
MAV_0600|M.avium_104                TEANGMGTMCRADDDAVTVATTCGRPFADFELRID-----------DSGE
MUL_4126|M.ulcerans_Agy99           TEANGMGTMCRADDDALTVATTCGRPFADFELRIGP----------DTGE
TH_2068|M.thermoresistible__bu      TEASGFGTMCRPEDDAVTVATTCGRPIAGFELRIDNPA------EDGTGE
MLBr_02546|M.leprae_Br4923          TEIAFATIAG--PKDLQINSATVGPVVKGVKVKILD-DSGKEVPRGQVGR
                                    **           ..      * *     .::::              *.

Mb2533c|M.bovis_AF2122/97           FCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIK
Rv2505c|M.tuberculosis_H37Rv        FCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIK
MMAR_3852|M.marinum_M               FCTRGYSVMSGYWKAPERTAEVIDPEGWMHTGDLALMDECGYVQITGRIK
MSMEG_5649|M.smegmatis_MC2_155      FCTRGYSVMLGYWNDDEKTREAVDADGWMHTGDLAVMREDGYCTIVGRIK
Mvan_4008|M.vanbaalenii_PYR-1       FCTRGYSVMLGYWGDEDRTREAVDADGWMHTGDLAVMRDDGYCMIVGRIK
Mflv_4867|M.gilvum_PYR-GCK          FCTRGYSVMLGYWREDEKTAQAIDADGWMHTGDLAVMRPDGYCNIVGRIK
MAB_4377c|M.abscessus_ATCC_199      LCTRGYSVMLGYWNDEAHTREVLDTDGWMHTGDLAVMRDDGYCTIIGRLK
MAV_0600|M.avium_104                VLLRGPNVMLGYLDDPDATAAAIDADGWLHTGDIGVLDEAGNLRITDRLK
MUL_4126|M.ulcerans_Agy99           VLLRGPNVMLGYLDDPRATAAAIDADGWLHTGDIGVLDEAGNLRITDRLK
TH_2068|M.thermoresistible__bu      VLLRGPNVMLGYLDDPEATAAAIDADGWLHTGDVGKVDERGNLTITDRLK
MLBr_02546|M.leprae_Br4923          IFVGNAFPFEGYTGG----GGKQIIDGLLSSGDVGYFDEHDLLYISGRDD
                                    .   .   : **             :* : :**:. .   .   * .* .

Mb2533c|M.bovis_AF2122/97           DLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN
Rv2505c|M.tuberculosis_H37Rv        DLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN
MMAR_3852|M.marinum_M               DIVVRGGENISPREIEEFLHSHPDIVDAHVVGVPDERMGEELMAVVKLRA
MSMEG_5649|M.smegmatis_MC2_155      DMVIRGGENIYPREIEEFLYTHPDIDDAQVIGVPDERYGEEICAWIRMKP
Mvan_4008|M.vanbaalenii_PYR-1       DMVIRGGENVYPREIEEFLHTHPDIDDVQVIGVPDERYGEEICAWIKVRA
Mflv_4867|M.gilvum_PYR-GCK          DVVIRGGENIYPREIEEFLYTHPDVEDAHVIGVPDDRYGEEVCAWIRMRP
MAB_4377c|M.abscessus_ATCC_199      DMVIRGGENIYPREIEEFLLTHPDIEDVHVVGVPDEKYGEELCAWVRMRP
MAV_0600|M.avium_104                DMYICGGFNVYPAEVEQVLARMEGVADAAVIGVPDERLGEVGRAFVVPRP
MUL_4126|M.ulcerans_Agy99           DMYICGGFNVYPAEVEQVLARLDGVADVAVIGIPDHRLGEVGRAFIVARP
TH_2068|M.thermoresistible__bu      DMYICGGFNVYPAEVEQVLARLDGVAEAAVIGVPDQRLGEVGKAFVVRRP
MLBr_02546|M.leprae_Br4923          EMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVKKQ
                                    :: : ** *: * *:*:.:     : :  .:*: * . *    * :  : 

Mb2533c|M.bovis_AF2122/97           DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQA
Rv2505c|M.tuberculosis_H37Rv        DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQA
MMAR_3852|M.marinum_M               GAPELTTGLLREYCAGQIAKFKIPRYLRLVDEFPMTVTGKVRKVEMRQQA
MSMEG_5649|M.smegmatis_MC2_155      GRPPLDADKVREFASGKLAHYKIPRYVHVVDEFPMTVTGKIRKVQMREET
Mvan_4008|M.vanbaalenii_PYR-1       GAAPLDAHAVREFAAGKLAHYKIPRYVHMTDDFPMTVTGKVRKIDMRAET
Mflv_4867|M.gilvum_PYR-GCK          GRTALDAAAVREFATDKLAHYKIPRYVHVVDEFPMTVTGKIRKVEMREVS
MAB_4377c|M.abscessus_ATCC_199      DRVVIDAVAIRAFASGRLAHYKIPRYVHVVESFPMTVTGKVRKIEMRQQT
MAV_0600|M.avium_104                G-AQLDEQSVIAYTRDHLANFKAPRSVRFVDALPRNSGGKVVKPQLRELD
MUL_4126|M.ulcerans_Agy99           G-FNLDEKSVIDYTREHLANFKAPRSVRFVDTLPRNAGGKVVKPQLRELA
TH_2068|M.thermoresistible__bu      G-ATLDEQAVIAYCKQHLANFKVPRSVEFLDALPRNPGGKVVKPLLRERA
MLBr_02546|M.leprae_Br4923          D-ATIDEDAIKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELRDFE
                                    .   :    :  :   ::*.:* ** : . : :* .  **: *  :*   

Mb2533c|M.bovis_AF2122/97           LEYLRGQQ-------
Rv2505c|M.tuberculosis_H37Rv        LEYLRGQQ-------
MMAR_3852|M.marinum_M               IEYLRGQH-------
MSMEG_5649|M.smegmatis_MC2_155      VALLGLEA-------
Mvan_4008|M.vanbaalenii_PYR-1       VRILGL---------
Mflv_4867|M.gilvum_PYR-GCK          ARLLGL---------
MAB_4377c|M.abscessus_ATCC_199      IQIFGLPEPGRTDEQ
MAV_0600|M.avium_104                ---------------
MUL_4126|M.ulcerans_Agy99           ---------------
TH_2068|M.thermoresistible__bu      ---------------
MLBr_02546|M.leprae_Br4923          VH-------------