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M. vanbaalenii PYR-1 Mvan_4007 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 4284602 - 4285699
length: 365

MDFRYHTEHDDLRAALRGFLHQTAPAARVREVAAGDGCDISLWRRLCTELELPGLHLSQECGGAGGSLVE
AAIVFEELGRALTPVPMAATVFAIEAVLRLGDDRQRSRLLPALLSGERIATLAAARPDALDPARVTVRAD
RHAGRTELSGESSPVLHGHVADLFVVPAVADGRVALYVVAADAPGVTVDRLPSFDTTRPVARLRLQQAPA
EPLVAGPHDGIERVLDTARVLLSAEMLGGAEACLAMAVEYSCTREQFDRPIGSFQAVKHSCADMMIEIDA
TRAAVMFAAMSAADPDELRITAPLVKAQAADTFTLCAGAAFQVHGGIAFTWEHDMHLYFRRAKTTEALFG
GSAHHRSLLADRVGL

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_4007 - - 100% (365) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_0393 - 4e-51 36.76% (370) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4312 - 3e-46 35.41% (353) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1968c fadE18 1e-142 70.68% (365) acyl-CoA dehydrogenase FADE18
M. gilvum PYR-GCK Mflv_0345 - 6e-56 38.15% (367) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv1933c fadE18 1e-142 70.68% (365) acyl-CoA dehydrogenase FADE18
M. leprae Br4923 MLBr_00737 fadE25 8e-21 25.07% (383) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3123 - 4e-57 37.50% (368) putative acyl-CoA dehydrogenase
M. marinum M MMAR_2861 fadE18 1e-144 72.05% (365) acyl-CoA dehydrogenase FadE18
M. avium 104 MAV_1838 - 3e-53 37.50% (368) acyl-CoA dehydrogenase protein
M. smegmatis MC2 155 MSMEG_6585 - 1e-57 39.57% (369) acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4038 - 2e-70 41.76% (364) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_2893 fadE18 1e-144 71.78% (365) acyl-CoA dehydrogenase FadE18

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0345|M.gilvum_PYR-GCK          --------------------------MADTAG------EWVFSDEQNQLR
MSMEG_6585|M.smegmatis_MC2_155      MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETTEFRFTDEQGQLR
MAV_1838|M.avium_104                -----------------------------MTG--------LSLDESRELA
Mb1968c|M.bovis_AF2122/97           -------------------------------------MDFRYSTEQDDFR
Rv1933c|M.tuberculosis_H37Rv        -------------------------------------MDFRYSTEQDDFR
MMAR_2861|M.marinum_M               -------------------------------------MDFRYSTEQDDFR
MUL_2893|M.ulcerans_Agy99           -------------------------------------MDFRYSTEQDDFR
Mvan_4007|M.vanbaalenii_PYR-1       -------------------------------------MDFRYHTEHDDLR
TH_4038|M.thermoresistible__bu      ------------------VSTPPAERTKEVDEMTDIPDAFAATDAQDELR
MAB_3123|M.abscessus_ATCC_1997      ------MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLR
MLBr_00737|M.leprae_Br4923          ---------------------------MVGWSGNPLFDLFKLPEEHNELR
                                                                                   :: 

Mflv_0345|M.gilvum_PYR-GCK          AAVRAFCADHVDESSVRAAMES----DPPFDAKVWSRLGSELGVLGMAVP
MSMEG_6585|M.smegmatis_MC2_155      AAVRKFGAEYFDEQTVRRLMES----EPRFDPAVWARLGAELGVLGLAVP
MAV_1838|M.avium_104                RSVRAACERFAPEERVRAIAYNGGGVDAGFDTELWKVLCAQVGVAAIGMP
Mb1968c|M.bovis_AF2122/97           ASLRGFLGRGAP---VREMAAA-----DGSDRRLWQRLCTELELPALHVP
Rv1933c|M.tuberculosis_H37Rv        ASLRGFLGRGAP---VREMAAA-----DGSDRRLWQRLCTELELPALHVP
MMAR_2861|M.marinum_M               ESLRGFLRDQAPPARVRQVAAV-----GGHDKKLWHRLCAELELPALHAP
MUL_2893|M.ulcerans_Agy99           ESLRGFLRDQAPPARVRQVAAV-----GGHDKKLWHRLCAELELPALHAP
Mvan_4007|M.vanbaalenii_PYR-1       AALRGFLHQTAPAARVREVAAG-----DGCDISLWRRLCTELELPGLHLS
TH_4038|M.thermoresistible__bu      RTVRGFFEKKMPEHEVRRIMETP----EGYDRAVWRQMADQLGLQGVAIP
MAB_3123|M.abscessus_ATCC_1997      SLVRSWCERVWTPKHVRQIAEAG-----SVDLDAWRALGSELGVVGLSLP
MLBr_00737|M.leprae_Br4923          ATIRALAEKEIAPHAADVDQRAR------FPEEALAALN-ASGFNAIHVP
                                      :*           .                     :     . .:  .

Mflv_0345|M.gilvum_PYR-GCK          ESAGGAGGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAASGG----
MSMEG_6585|M.smegmatis_MC2_155      EADGGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVAASAGPV-R
MAV_1838|M.avium_104                EDLGGAGFDATALGVVAHELGRALAPVPFVASAVLATGLLLATRESDPDS
Mb1968c|M.bovis_AF2122/97           PEHGGLGATLVETAIAFAELGRALTPIP-FAATVFAIEAILRMGDDEQ-R
Rv1933c|M.tuberculosis_H37Rv        PEHGGLGATLVETAIAFAELGRALTPIP-FAATVFAIEAILRMGDDEQ-R
MMAR_2861|M.marinum_M               PEYGGAGGTLVETAIAFGELGRALTPVP-FAATILAIEAILRMGDSEQ-R
MUL_2893|M.ulcerans_Agy99           PEYGGAGGTLVETAIAFGELGRALTPVP-FAATILAIEAILRMGDSEQ-R
Mvan_4007|M.vanbaalenii_PYR-1       QECGGAGGSLVEAAIVFEELGRALTPVP-MAATVFAIEAVLRLGDDRQ-R
TH_4038|M.thermoresistible__bu      EEFGGSGFGYSELGVVVEETGRALLPGPFFGSVVLAGTALLCSADDAA-K
MAB_3123|M.abscessus_ATCC_1997      EQHGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSSGDDSA-L
MLBr_00737|M.leprae_Br4923          EEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELK
                                       ** *       :.  : . .    . . :.       :    .    

Mflv_0345|M.gilvum_PYR-GCK          QELLGPLVDGTRTAAFAVRDDAGAFDASSVEVQAVPTEQGWALSGTVERV
MSMEG_6585|M.smegmatis_MC2_155      DELLGALVEGARTAAFAVPDRAGAFDPALVGVTASADAT---LTGTVERI
MAV_1838|M.avium_104                EQRLSGLMEGHRTAAAAVTGDGGLWQRDSVTLVANANIDGWAVNGTVRHV
Mb1968c|M.bovis_AF2122/97           KRLLAGLLTGARIGTIAVSGHDVAS--ATTVRAVRRDG-RPALTGECTPV
Rv1933c|M.tuberculosis_H37Rv        KRLLAGLLTGARIGTIAVSGHDVAS--ATTVRAVRRDG-RPALTGECTPV
MMAR_2861|M.marinum_M               KGLLSGLLSGDRIGALAAAGPDLS---VTSVRAGRRDG-RPVLTGECAPV
MUL_2893|M.ulcerans_Agy99           KGLLSGLLSGDRIGALAAAGPDLS---VTSVRAGRRDG-RPVLTGECAPV
Mvan_4007|M.vanbaalenii_PYR-1       SRLLPALLSGERIATLAAARPDALDPARVTVRADRHAG-RTELSGESSPV
TH_4038|M.thermoresistible__bu      SRYLPGIATGETIAALALTEQSGRWSADAVQTTARHDGGRWIINGSKTFV
MAB_3123|M.abscessus_ATCC_1997      AEWVPALAAGEKTITLAGGRTRLA---DAITVSAESDTDGWKLTGDTEHV
MLBr_00737|M.leprae_Br4923          KQVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWI
                                       :  :       : *                         :.*    :

Mflv_0345|M.gilvum_PYR-GCK          VDAGAADVLLVAATTP-----DGVGLFVVEADSLGVQRIRLTTLDLTR--
MSMEG_6585|M.smegmatis_MC2_155      VDGAAADVFLVAATAP-----DGVALYAVDAS--DVQRTPLTTLDLTR--
MAV_1838|M.avium_104                LNGCAANDLVVVAKAD-----DQPALFLIDPMAEGVAVEAERVLDGTR--
Mb1968c|M.bovis_AF2122/97           LHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTPLPSFDITR--
Rv1933c|M.tuberculosis_H37Rv        LHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTPLPSFDITR--
MMAR_2861|M.marinum_M               LHGHVADLFVVPAESD-----GAVILYVVDAAAPGVAVVGLPSFDITR--
MUL_2893|M.ulcerans_Agy99           LHGHVADLFVVPAESD-----GAVILYVVDAAAPGVAVVGLPSFDITR--
Mvan_4007|M.vanbaalenii_PYR-1       LHGHVADLFVVPAVAD-----GRVALYVVAADAPGVTVDRLPSFDTTR--
TH_4038|M.thermoresistible__bu      LDGHAADLLLVAARTD-----SGISLLAVDQTE-GLTRRMLSTLDPTR--
MAB_3123|M.abscessus_ATCC_1997      PDGATADVILVLADTD-----SGPSLFAVDGDAPGVDRHSLATLDMTR--
MLBr_00737|M.leprae_Br4923          TNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGS
                                     ..  :    * * :      .      :     ..           :  

Mflv_0345|M.gilvum_PYR-GCK          PQATVGLLDA---PAQLIAGPEEAERVITHALQVGAALLAVEQVGAAQHL
MSMEG_6585|M.smegmatis_MC2_155      PQATIALTDT---PGRLVSGPGEAERVIGHALQVGAALLAVEQVGAAQHL
MAV_1838|M.avium_104                PMATITFTGA---TALKLTGREAVDTIIEHNIDVALAVLSAEQVGACERV
Mb1968c|M.bovis_AF2122/97           PVATLRLAGS---PAEPLTAG--TPDDMERVLDVARVLLAAEMLGGAEAC
Rv1933c|M.tuberculosis_H37Rv        PVATLRLAGS---PAEPLTAG--TPDDMERVLDVARVLLAAEMLGGAEAC
MMAR_2861|M.marinum_M               PVAKLRLVRA---PAEALAAS--SADEVARLLDVARVLLAAEMLGGAEAC
MUL_2893|M.ulcerans_Agy99           PVAKLRLVRA---PAEALAAS--SADEVARLLDVARVLLAAEMLGGAEAC
Mvan_4007|M.vanbaalenii_PYR-1       PVARLRLQQA---PAEPLVAG--PHDGIERVLDTARVLLSAEMLGGAEAC
TH_4038|M.thermoresistible__bu      RQGRIDFTDT---PAELIGAEGQAWPSLSHALDIAAALLALEQVGGAQRC
MAB_3123|M.abscessus_ATCC_1997      RQANIHFNSA---PARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAHM
MLBr_00737|M.leprae_Br4923          PTTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGA
                                        : :          :             ::     :. :  * .   

Mflv_0345|M.gilvum_PYR-GCK          LDLSVDYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHAVWALS
MSMEG_6585|M.smegmatis_MC2_155      LDLSVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHAVWALA
MAV_1838|M.avium_104                LEIACEYARTREQFGRPIGSFQAIKHKCADMLVDLEWARSASQAALEAVV
Mb1968c|M.bovis_AF2122/97           LDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAA
Rv1933c|M.tuberculosis_H37Rv        LDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAA
MMAR_2861|M.marinum_M               LDLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAA
MUL_2893|M.ulcerans_Agy99           LDLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAA
Mvan_4007|M.vanbaalenii_PYR-1       LAMAVEYSCTREQFDRPIGSFQAVKHSCADMMIEIDATRAAVMFAAMSAA
TH_4038|M.thermoresistible__bu      LEIAVDYAKTRHQFGKPIGSFQAIRHRFADLMLEIECARGAAQYAVYAAA
MAB_3123|M.abscessus_ATCC_1997      LDVTTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHD
MLBr_00737|M.leprae_Br4923          LDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAE
                                    *  :  *:  * **.. *.:**:::.  **       .*     *     

Mflv_0345|M.gilvum_PYR-GCK          DGS-DDPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEHQAHLYYKR
MSMEG_6585|M.smegmatis_MC2_155      DGS-DDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEHQAHLYFKR
MAV_1838|M.avium_104                SGE-RD--WRASMAKAVCSESLRNAAHANVQIHGGIGFTWEDSAHLYLRR
Mb1968c|M.bovis_AF2122/97           NG--DELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
Rv1933c|M.tuberculosis_H37Rv        NG--DELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
MMAR_2861|M.marinum_M               GG--DELHATAPLAKAQAADTYVLCAGSAIQVHGGIAFTWEHDLHLYFRR
MUL_2893|M.ulcerans_Agy99           GG--DELHATAPLAKAQAAGTYVLCAGSAIQVHGGIAFTWEHDLHLYFRR
Mvan_4007|M.vanbaalenii_PYR-1       DP--DELRITAPLVKAQAADTFTLCAGAAFQVHGGIAFTWEHDMHLYFRR
TH_4038|M.thermoresistible__bu      RGL-DELPAAASLAKAYCTDVYTKAAGANIQIHGGIGFTWEHPAHMYFKR
MAB_3123|M.abscessus_ATCC_1997      HPSLDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYKR
MLBr_00737|M.leprae_Br4923          RGE-PDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRD
                                         :     .  :   :      :   .* .*. .:* :   . : : 

Mflv_0345|M.gilvum_PYR-GCK          AYTDAALLGGAEEHRARVADFVLVVAPEKD-----APRVATGMPS
MSMEG_6585|M.smegmatis_MC2_155      ATTDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATGTN-
MAV_1838|M.avium_104                ARTDEVLLGGPGQHWDRVGLRVL----------------------
Mb1968c|M.bovis_AF2122/97           AKTTEALFGSSARNRALLAERAGLVKA------------------
Rv1933c|M.tuberculosis_H37Rv        AKTTEALFGSSARNRALLAERAGLVKA------------------
MMAR_2861|M.marinum_M               AKTTEALFGSSAHHRSLLADRVGL---------------------
MUL_2893|M.ulcerans_Agy99           AKTTEALFGSSAHHRSLLADRVGL---------------------
Mvan_4007|M.vanbaalenii_PYR-1       AKTTEALFGGSAHHRSLLADRVGL---------------------
TH_4038|M.thermoresistible__bu      AKSSEHLLGDAAYHRGLLADRAGI---------------------
MAB_3123|M.abscessus_ATCC_1997      AVSNSALFGGRAVHAERIAKEVIDA--------------------
MLBr_00737|M.leprae_Br4923          AKITQIYEGTNQIQRVVMSRALLR---------------------
                                    *       *    :   :.

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_4007	-	-	100% (365)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_0393	-	4e-51	36.76% (370)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4312	-	3e-46	35.41% (353)	acyl-CoA dehydrogenase domain-containing protein