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M. marinum M MMAR_2596 (-)

annotation: PE-PGRS family protein
coordinates: 3164212 - 3165732
length: 506

MSYLTVAPEALSAATSDAAEIGSALAAANAAAAARTAGLLSAGGDEVSAAIAAVFSAHGVQYQAISAQMA
QFHRQFAQALSAANRSYALAEAANASPLQAIEQQLLAAINAPTQTLLGRPLIGNGADGAPGQNGAAGGLL
WGNGGAGGAGTATHTAGGNGGDAGLIGNGGAGGAGFNAGNGAAGGAGGAGGHGGWLYGNGGVGGVGGTGG
AGVPAVPTGGDGGAGGVGGAAGLWGDGGAGGAGGQGGAGRVGAAGGASSGGTGGHGGVGGIGGSGGAGGW
VAGNGGAGGAGGAGGMGGMGGTGASIGGGGGTGGAGGTGAAGGDGGWLFGDGGSGGAGGAGGQGGAGRGS
EIGGGAGGAGSVGGAGGAGGTGAWLFGNGGSGGAGGAGGMGGNGGNGVGNPGDGGDGGGGGAGASGGDGG
WLWGSGGNGGSGGAGRDGADGGVDPKSGRTGATGDGGDGGDGGDGGDAALVGNGGNGGAGGSGVTDGAGG
RGGAGGGLYGTPGMSG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2596--100% (506)PE-PGRS family protein
M. marinum MMMAR_0837-e-16253.57% (588) PE-PGRS family protein
M. marinum MMMAR_4223-e-15750.74% (611) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1476cPE_PGRS261e-17061.87% (514) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-5e-9947.86% (491) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1441cPE_PGRS261e-16961.48% (514) PE-PGRS family protein
M. leprae Br4923MLBr_01183-2e-1238.54% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-4738.02% (384) hypothetical protein MAB_4284c
M. avium 104MAV_4827-2e-2645.56% (169) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-2e-8142.89% (457) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-7e-4042.61% (284) PUTATIVE -
M. ulcerans Agy99MUL_3292-1e-15953.10% (612) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-9847.65% (489) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2596|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2596|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2596|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2596|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2596|M.marinum_M               --------------------------------------------------
MUL_3292|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------MSIIDFILN
MAV_4827|M.avium_104                ----------------------------------------------MNIV
                                                                                      

TH_3810|M.thermoresistible__bu      ------------VDGDGGSGGRTGLFSKLS---------RGGDGGD----
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Mb1476c|M.bovis_AF2122/97           -------MS-NVMVVPGMLSAAAADVASIG---AALSAANGAAAPT----
Rv1441c|M.tuberculosis_H37Rv        -------MS-NVMVVPGMLSAAAADVASIG---AALSAANGAAAPT----
MMAR_2596|M.marinum_M               -------MS-YLTVAPEALSAATSDAAEIG---SALAAANAAAAAR----
MUL_3292|M.ulcerans_Agy99           -------MS-YVIAAPEMLAGAATDLAGIG---AALQSANGAAAAP----
MLBr_01183|M.leprae_Br4923          -------MPLFLNAEPQALTAAANTLEGLS---AATVASNAAAAQL----
MAB_4284c|M.abscessus_ATCC_199      LFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASN----
MAV_4827|M.avium_104                LGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDR----
                                                                             .        

TH_3810|M.thermoresistible__bu      --------------------GGLGGNGGHGGGTGIISLLSLAG--NGGNG
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
Mb1476c|M.bovis_AF2122/97           -------------------TAGVLAAGADEVSAAIASLFSGYA--RDYQA
Rv1441c|M.tuberculosis_H37Rv        -------------------TAGVLAAGADEVSAAIASLFSGYA--RDYQA
MMAR_2596|M.marinum_M               -------------------TAGLLSAGGDEVSAAIAAVFSAHG--VQYQA
MUL_3292|M.ulcerans_Agy99           -------------------ITGVLAAGADEISAAVAALFSGHA--LDYQA
MLBr_01183|M.leprae_Br4923          -------------------TTEIAPPAADDVSILLAHFFSGHG--RQYQA
MAB_4284c|M.abscessus_ATCC_199      --------------YGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILS
MAV_4827|M.avium_104                ------------------VISAILGTREGAADAGLQLSSIGVTWTDQLEA
                                                                      :              .

TH_3810|M.thermoresistible__bu      GNGYRTTDNNALDGGHGGNGGNVGFFSLFN--------------------
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
Mb1476c|M.bovis_AF2122/97           LSAQMARFHQQFVQALTASVGSYAAAEAAN--------------------
Rv1441c|M.tuberculosis_H37Rv        LSAQMARFHQQFVQALTASVGSYAAAEAAN--------------------
MMAR_2596|M.marinum_M               ISAQMAQFHRQFAQALSAANRSYALAEAAN--------------------
MUL_3292|M.ulcerans_Agy99           LSTQMAGFHQQFVTALNSAGASYAAAEAAS--------------------
MLBr_01183|M.leprae_Br4923          HASQGATNHQDLIQSLLTSSSAYAGTETAN--------------------
MAB_4284c|M.abscessus_ATCC_199      PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSP----------------
MAV_4827|M.avium_104                AALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG-----------YER
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
Mb1476c|M.bovis_AF2122/97           -ASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG---------------
Rv1441c|M.tuberculosis_H37Rv        -ASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG---------------
MMAR_2596|M.marinum_M               -ASPLQAIEQQLLAAINAPTQTLLGRPLIGNGADG---------------
MUL_3292|M.ulcerans_Agy99           -ANPLQAVEQQLLGVINAPTQALLGRPLIGDGTAG---------------
MLBr_01183|M.leprae_Br4923          -HDSL---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -SGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG----------------
MAV_4827|M.avium_104                TAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYG-----------DA
                                                                                      

TH_3810|M.thermoresistible__bu      ----------------LGGAGGWGGSG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
Mb1476c|M.bovis_AF2122/97           LPGQNGGAGG-----LLWGNGGNGGAG-------------DAAHPNGGNG
Rv1441c|M.tuberculosis_H37Rv        LPGQNGGAGG-----LLWGNGGNGGAG-------------DAAHPNGGNG
MMAR_2596|M.marinum_M               APGQNGAAGG-----LLWGNGGAGGAG-------------TATHTAGGNG
MUL_3292|M.ulcerans_Agy99           APGQNGGDGG-----LLWGNGGAGGVG-------------TAAHPTGGSG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AVAVGGSNSG----PIASGQGSTAVNG--------DVRDSNIINADHGSN
MAV_4827|M.avium_104                AGQLSAMVAGLEKLESLPGGLLLVGSG-------------VDVAPLKQVL
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1       QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
Mb1476c|M.bovis_AF2122/97           GDAGMFGNGGAG----------------------GAGYSP----------
Rv1441c|M.tuberculosis_H37Rv        GDAGMFGNGGAG----------------------GAGYSP----------
MMAR_2596|M.marinum_M               GDAGLIGNGGAG----------------------GAGFN-----------
MUL_3292|M.ulcerans_Agy99           GSAGLIGTGGAG----------------------GAGYGPAAQTGATGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGVDQSQTRVGG---------------DYTNVSGHGSADIDKSVTVVDDH
MAV_4827|M.avium_104                QTTTFLDVSVAE-----------------------EPETALARGAALAAA
                                                                                      

TH_3810|M.thermoresistible__bu      ------------VDGVDVVGGNPD--------------------------
Mflv_5091|M.gilvum_PYR-GCK          -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
Mb1476c|M.bovis_AF2122/97           ------------AAGTGAAGGAGGAGGAGG--WLSGNGG-----------
Rv1441c|M.tuberculosis_H37Rv        ------------AAGTGAAGGAGGAGGAGG--WLSGNGG-----------
MMAR_2596|M.marinum_M               -------------AGNGAAGGAGGAGGHGG--WLYGNGG-----------
MUL_3292|M.ulcerans_Agy99           GGVGGTGGSGLDGPDSGAAGGAGGSGGSGGAARLFGNGG-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG----------T
MAV_4827|M.avium_104                NAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPE-----------
                                                                                      

TH_3810|M.thermoresistible__bu      -----------------------------------------------GGT
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
Mb1476c|M.bovis_AF2122/97           AGGNGGTGASGADGGGGLPPVPASP----------------------GGN
Rv1441c|M.tuberculosis_H37Rv        AGGNGGTGASGADGGGGLPPVPASP----------------------GGN
MMAR_2596|M.marinum_M               VGGVGGT------GGAGVPAVPT------------------------GGD
MUL_3292|M.ulcerans_Agy99           AGGSGGK------GGNGGSAIET------------------------GND
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      STSAGGSAAVGGNAGLAGNAGLAGN----------------------AGL
MAV_4827|M.avium_104                PGDDELAYSAVGEEDAESPTVVIEK----------------------LFL
                                                                                      

TH_3810|M.thermoresistible__bu      PGAHGESHTPGVYTD-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
Mb1476c|M.bovis_AF2122/97           GGGGGAGGAAGMFGT-----------------------------------
Rv1441c|M.tuberculosis_H37Rv        GGGGDAGGAAGMFGT-----------------------------------
MMAR_2596|M.marinum_M               GGAGGVGGAAGLWGD-----------------------------------
MUL_3292|M.ulcerans_Agy99           GAAGAGGHGGWLVGN-----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAGLAGN-----------------------------------
MAV_4827|M.avium_104                PEDSEPRRRPVLLVG-----------------------------------
                                                                                      

TH_3810|M.thermoresistible__bu      -------------RQGEDGEDGTGTGIGGRGGNGG---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
Mb1476c|M.bovis_AF2122/97           -----------GGAGGTGGDGGAG---GAGDSPNS---------------
Rv1441c|M.tuberculosis_H37Rv        -----------GGAGGTGGDGGAG---GAGDSPNS---------------
MMAR_2596|M.marinum_M               -----------GGAGGAGGQGGAG-RVGAAGGASS---------------
MUL_3292|M.ulcerans_Agy99           -----------GGIGGDGGSGGVGGDAGAYGPPAN---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------AGLAGNAGLAGNAGLAGNAGLAGNAG-------------
MAV_4827|M.avium_104                -----------SGLAVVGISAVLALEIALAIGIRTTG------------T
                                                                                      

TH_3810|M.thermoresistible__bu      ---SSSGTHPMAEDGEHVKALDGRPGLDGGNGSHGGNGGHGGRGGFLGIG
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
Mb1476c|M.bovis_AF2122/97           ---GANGARGGDGGNG---------AAGGAGGRLFGNGGAGGNG---GTA
Rv1441c|M.tuberculosis_H37Rv        ---GANGARGGDGGNG---------AAGGAGGRLFGNGGAGGNG---GTA
MMAR_2596|M.marinum_M               ---GGTGGHGGVGGIG---------GSGGAGGWVAGNGGAG------GAG
MUL_3292|M.ulcerans_Agy99           ---GGAGGHGGMGGVGGDA--GLLFGSGGAGG-VGGNGAIGGTGVMSGAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-LAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104                VALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVA
                                                                                      

TH_3810|M.thermoresistible__bu      GSGGWGGHGGNGGDTDADGGNGGDGGNG------------GSAGRGGTGG
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
Mb1476c|M.bovis_AF2122/97           GQGGDGGTALGAG-GIG--GDGGTGGAG---------------GTGGTAG
Rv1441c|M.tuberculosis_H37Rv        GQGGDGGTALGAG-GIG--GDGGTGGAG---------------GTGGTAG
MMAR_2596|M.marinum_M               GAGGMGGMGGTGA-SIG--GGGGTGGAG---------------GTGAAGG
MUL_3292|M.ulcerans_Agy99           GAGGDGGNGGYAQ-LIGDGGGGGAGGAGYSASGLPPAGIGAPGGAGGAGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAG-LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVLN
MAV_4827|M.avium_104                APLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPV
                                                                                      

TH_3810|M.thermoresistible__bu      LR---------------------------GVFGINGGNGR----------
Mflv_5091|M.gilvum_PYR-GCK          AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1       AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155      AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
Mb1476c|M.bovis_AF2122/97           IG---------------------------GSSAGAGGAGG----------
Rv1441c|M.tuberculosis_H37Rv        IG---------------------------GSSAGAGGAGG----------
MMAR_2596|M.marinum_M               DG---------------------------GWLFGDGGSGG----------
MUL_3292|M.ulcerans_Agy99           SG---------------------------GWLVGNGGAGG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TG-------------------------VSGAIGGSSHVGG----------
MAV_4827|M.avium_104                SP--------------------------PQLLAPPRLSVPQPVQPPVRVP
                                                                                      

TH_3810|M.thermoresistible__bu      --------AGLGGRGX----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1       -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155      SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
Mb1476c|M.bovis_AF2122/97           -------DGGAGGNG-----------------------------------
Rv1441c|M.tuberculosis_H37Rv        -------DGGAGGTG-----------------------------------
MMAR_2596|M.marinum_M               -------AGGAGGQG-----------------------------------
MUL_3292|M.ulcerans_Agy99           -------IGGIGASGS----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --AINESLGGSGSVGG----------------------------------
MAV_4827|M.avium_104                QPPSPPQVGGTVPQSP----------------------------------
                                                                                      

TH_3810|M.thermoresistible__bu      ----------------------------------------------XXXG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155      GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
Mb1476c|M.bovis_AF2122/97           ---------GGSSMIG--------------GKGG------------TGGN
Rv1441c|M.tuberculosis_H37Rv        ---------GGSSMIG--------------GKGG------------TGGN
MMAR_2596|M.marinum_M               -------GAGRGSEIG-------------GGAGG------------AGSV
MUL_3292|M.ulcerans_Agy99           --FGAPSGQGGNGGIGGAAGLF-----GQGGAGGNGGQGGGDDFALSGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---STAVGGGAHTGVGGGVSTG-------VGVGSHVGGGISESLGGSGSV
MAV_4827|M.avium_104                ------PQHQTPPGEGTPPKPD--------GPGNYGG-----GHVPTPGA
                                                                                      

TH_3810|M.thermoresistible__bu      GGVGAAVRSGNGVFSGGGGTPSAG--------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155      GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
Mb1476c|M.bovis_AF2122/97           GGVGGTGGASALTIGNGSSAGAGG--------------------------
Rv1441c|M.tuberculosis_H37Rv        GGVGGTGGASALTIGNGSSAGAGG--------------------------
MMAR_2596|M.marinum_M               GGAGGAGGTGAWLFGNGGSGGAGG--------------------------
MUL_3292|M.ulcerans_Agy99           GGAGGAGGHGGQLYGDGGGGGAGG--------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGSTAVGGGAHTGVGGGVSTGVGVG-------------------------
MAV_4827|M.avium_104                GGSGGSGGGHVPTPGAGGSGGSGGG-------------------------
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1       GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155      GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
Mb1476c|M.bovis_AF2122/97           --------AGG------AGGTGGTG---------------------GYIE
Rv1441c|M.tuberculosis_H37Rv        --------AGG------AGGTGGTG---------------------GYIE
MMAR_2596|M.marinum_M               --------AGG---------MGGNG---------------------GNG-
MUL_3292|M.ulcerans_Agy99           --------MGGSVDIAESGVTGGRG---------------------GSGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------SHVGGGISESLGGSGSVG---------------------GSTA
MAV_4827|M.avium_104                --------------HVPTPGTGGPG---------------------GTGG
                                                                                      

TH_3810|M.thermoresistible__bu      FGVPTTIQFPAG--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1       SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155      AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
Mb1476c|M.bovis_AF2122/97           SLDGKGQAGNGG-------------------------NGGNGAAGGAGGG
Rv1441c|M.tuberculosis_H37Rv        SLDGKGQAGNGG-------------------------NGGNGAAGGAGGG
MMAR_2596|M.marinum_M               VGN-PGDGGDGG-------------------------GGGAGASGGDGG-
MUL_3292|M.ulcerans_Agy99           VGGGAGLWGAGG-------------------------QGGDGAQGGDGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGGGAHTGVGGG------------------------VNTGVGVGSHVGGG
MAV_4827|M.avium_104                SGGGHVPTPGAG-------------------------TPGGSGGGHLPFP
                                                                                      

TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1       GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155      QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
Mb1476c|M.bovis_AF2122/97           G----TGAGG--------NGGAG---------------------------
Rv1441c|M.tuberculosis_H37Rv        G----TGAGG--------NGGAG---------------------------
MMAR_2596|M.marinum_M               ---WLWGSGG--------NGGSGGAGRDG----ADGGVDPKSGRTG----
MUL_3292|M.ulcerans_Agy99           GVDTTTGAGG--------DGGAGAGGGTSGFLYGNGGAGGAGGHGGG---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ISESLGGSGS--------VGGSTAVGGGAHTSAINDALG-----------
MAV_4827|M.avium_104                GAGSTPGGSG---------GGHLPTPG-----------------------
                                                                                      

TH_3810|M.thermoresistible__bu      -------SCTSRAVSREGIMPSSR--------AASARAGAACASSTSRSR
Mflv_5091|M.gilvum_PYR-GCK          ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1       ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155      GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
Mb1476c|M.bovis_AF2122/97           ------GNGGDGGPSQGGGNPGFG--------GDGGTGGPGG---VGVPD
Rv1441c|M.tuberculosis_H37Rv        ------GNGGDGGPSQGGGNPGFG--------GDGGTGGPGG---VGVPD
MMAR_2596|M.marinum_M               ----ATGDGGDGGDGGDGGDAALV--------GNGGNGGAGG---SGVTD
MUL_3292|M.ulcerans_Agy99           ----GPGMGGDGGDGGDGGRAQLI--------GTGGNGGAGGTAAPGGTD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------GSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSM
MAV_4827|M.avium_104                -----AGTPGGGLGGFGGGHAPAP--------GGGLGGGGGHAPAPGGGL
                                                                                      

TH_3810|M.thermoresistible__bu      RSFCCSRA--------------------------
Mflv_5091|M.gilvum_PYR-GCK          -GAGGSGGSGGSGGSGGSGGAAGDSDD-------
Mvan_1264|M.vanbaalenii_PYR-1       -GAGGSGGSGGSGGAGGSGGAAGDSD--------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGNGGADGTPGTAGTTGANNP-------
Mb1476c|M.bovis_AF2122/97           GIGGANG-------AQGKHG--------------
Rv1441c|M.tuberculosis_H37Rv        GIGGANG-------AQGKHG--------------
MMAR_2596|M.marinum_M               GAGGRGGAGGGLYGTPGMSG--------------
MUL_3292|M.ulcerans_Agy99           GTAGAAGKGGVLFGTDGATG--------------
MLBr_01183|M.leprae_Br4923          ----------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104                GGFGGGHSGGGLGGLGGGHK--------------