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MSYLTVAPEALSAATSDAAEIGSALAAANAAAAARTAGLLSAGGDEVSAAIAAVFSAHGVQYQAISAQMA QFHRQFAQALSAANRSYALAEAANASPLQAIEQQLLAAINAPTQTLLGRPLIGNGADGAPGQNGAAGGLL WGNGGAGGAGTATHTAGGNGGDAGLIGNGGAGGAGFNAGNGAAGGAGGAGGHGGWLYGNGGVGGVGGTGG AGVPAVPTGGDGGAGGVGGAAGLWGDGGAGGAGGQGGAGRVGAAGGASSGGTGGHGGVGGIGGSGGAGGW VAGNGGAGGAGGAGGMGGMGGTGASIGGGGGTGGAGGTGAAGGDGGWLFGDGGSGGAGGAGGQGGAGRGS EIGGGAGGAGSVGGAGGAGGTGAWLFGNGGSGGAGGAGGMGGNGGNGVGNPGDGGDGGGGGAGASGGDGG WLWGSGGNGGSGGAGRDGADGGVDPKSGRTGATGDGGDGGDGGDGGDAALVGNGGNGGAGGSGVTDGAGG RGGAGGGLYGTPGMSG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2596 | - | - | 100% (506) | PE-PGRS family protein |
M. marinum M | MMAR_0837 | - | e-162 | 53.57% (588) | PE-PGRS family protein |
M. marinum M | MMAR_4223 | - | e-157 | 50.74% (611) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1476c | PE_PGRS26 | 1e-170 | 61.87% (514) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 5e-99 | 47.86% (491) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1441c | PE_PGRS26 | 1e-169 | 61.48% (514) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 38.54% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 2e-47 | 38.02% (384) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 2e-26 | 45.56% (169) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-81 | 42.89% (457) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 7e-40 | 42.61% (284) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3292 | - | 1e-159 | 53.10% (612) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-98 | 47.65% (489) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2596|M.marinum_M -------------------------------------------------- MUL_3292|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2596|M.marinum_M -------------------------------------------------- MUL_3292|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2596|M.marinum_M -------------------------------------------------- MUL_3292|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2596|M.marinum_M -------------------------------------------------- MUL_3292|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2596|M.marinum_M -------------------------------------------------- MUL_3292|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------MSIIDFILN MAV_4827|M.avium_104 ----------------------------------------------MNIV TH_3810|M.thermoresistible__bu ------------VDGDGGSGGRTGLFSKLS---------RGGDGGD---- Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG Mb1476c|M.bovis_AF2122/97 -------MS-NVMVVPGMLSAAAADVASIG---AALSAANGAAAPT---- Rv1441c|M.tuberculosis_H37Rv -------MS-NVMVVPGMLSAAAADVASIG---AALSAANGAAAPT---- MMAR_2596|M.marinum_M -------MS-YLTVAPEALSAATSDAAEIG---SALAAANAAAAAR---- MUL_3292|M.ulcerans_Agy99 -------MS-YVIAAPEMLAGAATDLAGIG---AALQSANGAAAAP---- MLBr_01183|M.leprae_Br4923 -------MPLFLNAEPQALTAAANTLEGLS---AATVASNAAAAQL---- MAB_4284c|M.abscessus_ATCC_199 LFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASN---- MAV_4827|M.avium_104 LGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDR---- . TH_3810|M.thermoresistible__bu --------------------GGLGGNGGHGGGTGIISLLSLAG--NGGNG Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG Mb1476c|M.bovis_AF2122/97 -------------------TAGVLAAGADEVSAAIASLFSGYA--RDYQA Rv1441c|M.tuberculosis_H37Rv -------------------TAGVLAAGADEVSAAIASLFSGYA--RDYQA MMAR_2596|M.marinum_M -------------------TAGLLSAGGDEVSAAIAAVFSAHG--VQYQA MUL_3292|M.ulcerans_Agy99 -------------------ITGVLAAGADEISAAVAALFSGHA--LDYQA MLBr_01183|M.leprae_Br4923 -------------------TTEIAPPAADDVSILLAHFFSGHG--RQYQA MAB_4284c|M.abscessus_ATCC_199 --------------YGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILS MAV_4827|M.avium_104 ------------------VISAILGTREGAADAGLQLSSIGVTWTDQLEA : . TH_3810|M.thermoresistible__bu GNGYRTTDNNALDGGHGGNGGNVGFFSLFN-------------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT Mb1476c|M.bovis_AF2122/97 LSAQMARFHQQFVQALTASVGSYAAAEAAN-------------------- Rv1441c|M.tuberculosis_H37Rv LSAQMARFHQQFVQALTASVGSYAAAEAAN-------------------- MMAR_2596|M.marinum_M ISAQMAQFHRQFAQALSAANRSYALAEAAN-------------------- MUL_3292|M.ulcerans_Agy99 LSTQMAGFHQQFVTALNSAGASYAAAEAAS-------------------- MLBr_01183|M.leprae_Br4923 HASQGATNHQDLIQSLLTSSSAYAGTETAN-------------------- MAB_4284c|M.abscessus_ATCC_199 PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSP---------------- MAV_4827|M.avium_104 AALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG-----------YER TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------- Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------- MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH Mb1476c|M.bovis_AF2122/97 -ASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG--------------- Rv1441c|M.tuberculosis_H37Rv -ASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG--------------- MMAR_2596|M.marinum_M -ASPLQAIEQQLLAAINAPTQTLLGRPLIGNGADG--------------- MUL_3292|M.ulcerans_Agy99 -ANPLQAVEQQLLGVINAPTQALLGRPLIGDGTAG--------------- MLBr_01183|M.leprae_Br4923 -HDSL--------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -SGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG---------------- MAV_4827|M.avium_104 TAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYG-----------DA TH_3810|M.thermoresistible__bu ----------------LGGAGGWGGSG----------------------- Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS Mb1476c|M.bovis_AF2122/97 LPGQNGGAGG-----LLWGNGGNGGAG-------------DAAHPNGGNG Rv1441c|M.tuberculosis_H37Rv LPGQNGGAGG-----LLWGNGGNGGAG-------------DAAHPNGGNG MMAR_2596|M.marinum_M APGQNGAAGG-----LLWGNGGAGGAG-------------TATHTAGGNG MUL_3292|M.ulcerans_Agy99 APGQNGGDGG-----LLWGNGGAGGVG-------------TAAHPTGGSG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVAVGGSNSG----PIASGQGSTAVNG--------DVRDSNIINADHGSN MAV_4827|M.avium_104 AGQLSAMVAGLEKLESLPGGLLLVGSG-------------VDVAPLKQVL TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ- Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ- MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY Mb1476c|M.bovis_AF2122/97 GDAGMFGNGGAG----------------------GAGYSP---------- Rv1441c|M.tuberculosis_H37Rv GDAGMFGNGGAG----------------------GAGYSP---------- MMAR_2596|M.marinum_M GDAGLIGNGGAG----------------------GAGFN----------- MUL_3292|M.ulcerans_Agy99 GSAGLIGTGGAG----------------------GAGYGPAAQTGATGGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVGG---------------DYTNVSGHGSADIDKSVTVVDDH MAV_4827|M.avium_104 QTTTFLDVSVAE-----------------------EPETALARGAALAAA TH_3810|M.thermoresistible__bu ------------VDGVDVVGGNPD-------------------------- Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG----------- Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG----------- MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA Mb1476c|M.bovis_AF2122/97 ------------AAGTGAAGGAGGAGGAGG--WLSGNGG----------- Rv1441c|M.tuberculosis_H37Rv ------------AAGTGAAGGAGGAGGAGG--WLSGNGG----------- MMAR_2596|M.marinum_M -------------AGNGAAGGAGGAGGHGG--WLYGNGG----------- MUL_3292|M.ulcerans_Agy99 GGVGGTGGSGLDGPDSGAAGGAGGSGGSGGAARLFGNGG----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG----------T MAV_4827|M.avium_104 NAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPE----------- TH_3810|M.thermoresistible__bu -----------------------------------------------GGT Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV Mb1476c|M.bovis_AF2122/97 AGGNGGTGASGADGGGGLPPVPASP----------------------GGN Rv1441c|M.tuberculosis_H37Rv AGGNGGTGASGADGGGGLPPVPASP----------------------GGN MMAR_2596|M.marinum_M VGGVGGT------GGAGVPAVPT------------------------GGD MUL_3292|M.ulcerans_Agy99 AGGSGGK------GGNGGSAIET------------------------GND MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 STSAGGSAAVGGNAGLAGNAGLAGN----------------------AGL MAV_4827|M.avium_104 PGDDELAYSAVGEEDAESPTVVIEK----------------------LFL TH_3810|M.thermoresistible__bu PGAHGESHTPGVYTD----------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD----------- Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN----------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP Mb1476c|M.bovis_AF2122/97 GGGGGAGGAAGMFGT----------------------------------- Rv1441c|M.tuberculosis_H37Rv GGGGDAGGAAGMFGT----------------------------------- MMAR_2596|M.marinum_M GGAGGVGGAAGLWGD----------------------------------- MUL_3292|M.ulcerans_Agy99 GAAGAGGHGGWLVGN----------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGN----------------------------------- MAV_4827|M.avium_104 PEDSEPRRRPVLLVG----------------------------------- TH_3810|M.thermoresistible__bu -------------RQGEDGEDGTGTGIGGRGGNGG--------------- Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG--------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG--------------- MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ Mb1476c|M.bovis_AF2122/97 -----------GGAGGTGGDGGAG---GAGDSPNS--------------- Rv1441c|M.tuberculosis_H37Rv -----------GGAGGTGGDGGAG---GAGDSPNS--------------- MMAR_2596|M.marinum_M -----------GGAGGAGGQGGAG-RVGAAGGASS--------------- MUL_3292|M.ulcerans_Agy99 -----------GGIGGDGGSGGVGGDAGAYGPPAN--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------AGLAGNAGLAGNAGLAGNAGLAGNAG------------- MAV_4827|M.avium_104 -----------SGLAVVGISAVLALEIALAIGIRTTG------------T TH_3810|M.thermoresistible__bu ---SSSGTHPMAEDGEHVKALDGRPGLDGGNGSHGGNGGHGGRGGFLGIG Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG Mb1476c|M.bovis_AF2122/97 ---GANGARGGDGGNG---------AAGGAGGRLFGNGGAGGNG---GTA Rv1441c|M.tuberculosis_H37Rv ---GANGARGGDGGNG---------AAGGAGGRLFGNGGAGGNG---GTA MMAR_2596|M.marinum_M ---GGTGGHGGVGGIG---------GSGGAGGWVAGNGGAG------GAG MUL_3292|M.ulcerans_Agy99 ---GGAGGHGGMGGVGGDA--GLLFGSGGAGG-VGGNGAIGGTGVMSGAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-LAGNAGLAGNAGLAGNA MAV_4827|M.avium_104 VALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVA TH_3810|M.thermoresistible__bu GSGGWGGHGGNGGDTDADGGNGGDGGNG------------GSAGRGGTGG Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG Mb1476c|M.bovis_AF2122/97 GQGGDGGTALGAG-GIG--GDGGTGGAG---------------GTGGTAG Rv1441c|M.tuberculosis_H37Rv GQGGDGGTALGAG-GIG--GDGGTGGAG---------------GTGGTAG MMAR_2596|M.marinum_M GAGGMGGMGGTGA-SIG--GGGGTGGAG---------------GTGAAGG MUL_3292|M.ulcerans_Agy99 GAGGDGGNGGYAQ-LIGDGGGGGAGGAGYSASGLPPAGIGAPGGAGGAGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG-LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVLN MAV_4827|M.avium_104 APLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPV TH_3810|M.thermoresistible__bu LR---------------------------GVFGINGGNGR---------- Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------- Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------- MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG Mb1476c|M.bovis_AF2122/97 IG---------------------------GSSAGAGGAGG---------- Rv1441c|M.tuberculosis_H37Rv IG---------------------------GSSAGAGGAGG---------- MMAR_2596|M.marinum_M DG---------------------------GWLFGDGGSGG---------- MUL_3292|M.ulcerans_Agy99 SG---------------------------GWLVGNGGAGG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TG-------------------------VSGAIGGSSHVGG---------- MAV_4827|M.avium_104 SP--------------------------PQLLAPPRLSVPQPVQPPVRVP TH_3810|M.thermoresistible__bu --------AGLGGRGX---------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH Mb1476c|M.bovis_AF2122/97 -------DGGAGGNG----------------------------------- Rv1441c|M.tuberculosis_H37Rv -------DGGAGGTG----------------------------------- MMAR_2596|M.marinum_M -------AGGAGGQG----------------------------------- MUL_3292|M.ulcerans_Agy99 -------IGGIGASGS---------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --AINESLGGSGSVGG---------------------------------- MAV_4827|M.avium_104 QPPSPPQVGGTVPQSP---------------------------------- TH_3810|M.thermoresistible__bu ----------------------------------------------XXXG Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD Mb1476c|M.bovis_AF2122/97 ---------GGSSMIG--------------GKGG------------TGGN Rv1441c|M.tuberculosis_H37Rv ---------GGSSMIG--------------GKGG------------TGGN MMAR_2596|M.marinum_M -------GAGRGSEIG-------------GGAGG------------AGSV MUL_3292|M.ulcerans_Agy99 --FGAPSGQGGNGGIGGAAGLF-----GQGGAGGNGGQGGGDDFALSGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---STAVGGGAHTGVGGGVSTG-------VGVGSHVGGGISESLGGSGSV MAV_4827|M.avium_104 ------PQHQTPPGEGTPPKPD--------GPGNYGG-----GHVPTPGA TH_3810|M.thermoresistible__bu GGVGAAVRSGNGVFSGGGGTPSAG-------------------------- Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL Mb1476c|M.bovis_AF2122/97 GGVGGTGGASALTIGNGSSAGAGG-------------------------- Rv1441c|M.tuberculosis_H37Rv GGVGGTGGASALTIGNGSSAGAGG-------------------------- MMAR_2596|M.marinum_M GGAGGAGGTGAWLFGNGGSGGAGG-------------------------- MUL_3292|M.ulcerans_Agy99 GGAGGAGGHGGQLYGDGGGGGAGG-------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHTGVGGGVSTGVGVG------------------------- MAV_4827|M.avium_104 GGSGGSGGGHVPTPGAGGSGGSGGG------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG Mb1476c|M.bovis_AF2122/97 --------AGG------AGGTGGTG---------------------GYIE Rv1441c|M.tuberculosis_H37Rv --------AGG------AGGTGGTG---------------------GYIE MMAR_2596|M.marinum_M --------AGG---------MGGNG---------------------GNG- MUL_3292|M.ulcerans_Agy99 --------MGGSVDIAESGVTGGRG---------------------GSGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------SHVGGGISESLGGSGSVG---------------------GSTA MAV_4827|M.avium_104 --------------HVPTPGTGGPG---------------------GTGG TH_3810|M.thermoresistible__bu FGVPTTIQFPAG-------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV Mb1476c|M.bovis_AF2122/97 SLDGKGQAGNGG-------------------------NGGNGAAGGAGGG Rv1441c|M.tuberculosis_H37Rv SLDGKGQAGNGG-------------------------NGGNGAAGGAGGG MMAR_2596|M.marinum_M VGN-PGDGGDGG-------------------------GGGAGASGGDGG- MUL_3292|M.ulcerans_Agy99 VGGGAGLWGAGG-------------------------QGGDGAQGGDGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGGGAHTGVGGG------------------------VNTGVGVGSHVGGG MAV_4827|M.avium_104 SGGGHVPTPGAG-------------------------TPGGSGGGHLPFP TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------- Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------- MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS Mb1476c|M.bovis_AF2122/97 G----TGAGG--------NGGAG--------------------------- Rv1441c|M.tuberculosis_H37Rv G----TGAGG--------NGGAG--------------------------- MMAR_2596|M.marinum_M ---WLWGSGG--------NGGSGGAGRDG----ADGGVDPKSGRTG---- MUL_3292|M.ulcerans_Agy99 GVDTTTGAGG--------DGGAGAGGGTSGFLYGNGGAGGAGGHGGG--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGS--------VGGSTAVGGGAHTSAINDALG----------- MAV_4827|M.avium_104 GAGSTPGGSG---------GGHLPTPG----------------------- TH_3810|M.thermoresistible__bu -------SCTSRAVSREGIMPSSR--------AASARAGAACASSTSRSR Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG- Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG- MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN Mb1476c|M.bovis_AF2122/97 ------GNGGDGGPSQGGGNPGFG--------GDGGTGGPGG---VGVPD Rv1441c|M.tuberculosis_H37Rv ------GNGGDGGPSQGGGNPGFG--------GDGGTGGPGG---VGVPD MMAR_2596|M.marinum_M ----ATGDGGDGGDGGDGGDAALV--------GNGGNGGAGG---SGVTD MUL_3292|M.ulcerans_Agy99 ----GPGMGGDGGDGGDGGRAQLI--------GTGGNGGAGGTAAPGGTD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------GSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSM MAV_4827|M.avium_104 -----AGTPGGGLGGFGGGHAPAP--------GGGLGGGGGHAPAPGGGL TH_3810|M.thermoresistible__bu RSFCCSRA-------------------------- Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD------- Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP------- Mb1476c|M.bovis_AF2122/97 GIGGANG-------AQGKHG-------------- Rv1441c|M.tuberculosis_H37Rv GIGGANG-------AQGKHG-------------- MMAR_2596|M.marinum_M GAGGRGGAGGGLYGTPGMSG-------------- MUL_3292|M.ulcerans_Agy99 GTAGAAGKGGVLFGTDGATG-------------- MLBr_01183|M.leprae_Br4923 ---------------------------------- MAB_4284c|M.abscessus_ATCC_199 GSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH MAV_4827|M.avium_104 GGFGGGHSGGGLGGLGGGHK--------------