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M. ulcerans Agy99 MUL_3672 (-)

annotation: PE-PGRS family protein
coordinates: 4085372 - 4086748
length: 458

MAYVIADLEAMAAAAADLAGVNSAIAAANGIAAVPTTAVQACAGDQVSAAVAALFAAHAQGYQSISTQMS
AMHDQLVQTLSASSASYAGAEASNAAQASLDLINAPTQALLGRPLIGNGADGATVGRIGTPGGAGGLLYG
NGGRGGDSTLAGVSGGGGGYAGLIGNGGAGGTGGNGGSGGLGGNAWLLGSGGTGGTGGAGVSSGFGGTGG
NGGLGGLLYGSGGAGGTGGAGAAGAVLGGMGGLGGDARLFGTGGAGGTGGDNSLGLTGQGGQGGDAGAGG
ASGYGIGNGGAGGAAGDGGGAGSLGTGGNGGSGGRAALLYGVGRDGGAGGAGGDGVGSAGGSGGLGGAAG
LVDVGGDGGAGGAGGGAGGDGGAGAYLIGDGGDGGAGGHGGDGGAGGDGNAGSLAGGTGGNGGDAKVIGN
GGNGGDGGVRFGGGANGSGGTGGAAGLLGSPGSDGTTV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_3672--100% (458)PE-PGRS family protein
M. ulcerans Agy99MUL_3247-e-12148.72% (548) PE-PGRS family protein
M. ulcerans Agy99MUL_3056-e-11950.38% (532) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2186cPE_PGRS381e-12852.52% (497) hypothetical protein Mb2186c
M. gilvum PYR-GCKMflv_5091-1e-8144.49% (463) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1396cPE_PGRS251e-12752.54% (512) PE-PGRS family protein
M. leprae Br4923MLBr_01183-6e-1338.04% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-9e-4337.72% (334) hypothetical protein MAB_4284c
M. marinum MMMAR_3729-0.090.50% (484) PE-PGRS family protein, PE_PGRS25
M. avium 104MAV_4827-4e-2341.67% (180) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-6441.65% (425) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-4142.23% (296) PUTATIVE -
M. vanbaalenii PYR-1Mvan_1264-1e-8043.32% (464) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb2186c|M.bovis_AF2122/97           --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3672|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3729|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3672|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3729|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3672|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3729|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3672|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3729|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------------MSI
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3672|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3729|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      IDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVA
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           ------------------MSFVIAAPEVMAAAAT------------DLAN
Rv1396c|M.tuberculosis_H37Rv        ------------------MSFLFAQPEMLGAAAT------------DLAS
MUL_3672|M.ulcerans_Agy99           ------------------MAYVIADLEAMAAAAA------------DLAG
MMAR_3729|M.marinum_M               ------------------MAYVIADLEAMAAAAA------------DLAG
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923          -----------------MPLFLNAEPQALTAAAN------------TLEG
MAB_4284c|M.abscessus_ATCC_199      SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFL
MAV_4827|M.avium_104                -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAA
                                                                                      

Mb2186c|M.bovis_AF2122/97           IGSSISAASAAAAGPTMGILAAGADEVSVAISALFGSHAQGYQTLSAQLA
Rv1396c|M.tuberculosis_H37Rv        IGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQTYQALRTQAA
MUL_3672|M.ulcerans_Agy99           VNSAIAAANGIAAVPTTAVQACAGDQVSAAVAALFAAHAQGYQSISTQMS
MMAR_3729|M.marinum_M               VNSAIAAANGIAAVPTTAVQACAGDQVSAAVAALFAAHAQGYQSISAQMS
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MLBr_01183|M.leprae_Br4923          LSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGA
MAB_4284c|M.abscessus_ATCC_199      SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTT
MAV_4827|M.avium_104                TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARR
                                                                                      

Mb2186c|M.bovis_AF2122/97           AYHN----------------QFVRALNAGAGSYAS---------------
Rv1396c|M.tuberculosis_H37Rv        AFHQ----------------QIVQTLTSTAGAYAS---------------
MUL_3672|M.ulcerans_Agy99           AMHD----------------QLVQTLSASSASYAG---------------
MMAR_3729|M.marinum_M               AMHD----------------QLVQTLSASSASYAG---------------
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      IIS--------------------LLSLAGNGGNGG---------------
MLBr_01183|M.leprae_Br4923          TNHQ----------------DLIQSLLTSSSAYAG---------------
MAB_4284c|M.abscessus_ATCC_199      AIGDG----------------AVAVGGSNSGPIAS---------------
MAV_4827|M.avium_104                IDNVMLVS----------AFLAAAALAQNVGGAMG---------------
                                                                  .   .               

Mb2186c|M.bovis_AF2122/97           --------------------------------------------------
Rv1396c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3672|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3729|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           ------------AEAANVQQTLLNAIN----------------------A
Rv1396c|M.tuberculosis_H37Rv        ------------AEAANVEQQLLGAIN----------------------A
MUL_3672|M.ulcerans_Agy99           ------------AEASNAAQASLDLIN----------------------A
MMAR_3729|M.marinum_M               ------------AEASNAAQAFLDLIN----------------------A
Mflv_5091|M.gilvum_PYR-GCK          -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1       -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF
MLBr_01183|M.leprae_Br4923          --------------TETANHDSL---------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------GQGSTAVNGDVRDSN----------IINADHGSNVGVD
MAV_4827|M.avium_104                ----YERTAVLLVEPDTATLAVVETSD------------------GSIPD
                                                                                      

Mb2186c|M.bovis_AF2122/97           PTQTLLGRPLIG---------------------NGADGGP----------
Rv1396c|M.tuberculosis_H37Rv        PTMALLGRPLIG---------------------HGADGAPGT--------
MUL_3672|M.ulcerans_Agy99           PTQALLGRPLIG---------------------NGADG------------
MMAR_3729|M.marinum_M               PTQALLGRPLIG---------------------NGADG------------
Mflv_5091|M.gilvum_PYR-GCK          ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1       ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      SLFNLGGAGGWG--------------------GSGVDG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      QSQTRVGGDYTN------------------VSGHGSADIDKSVTVVDDHS
MAV_4827|M.avium_104                VYKQQIRAESYG---------------------DAAGQLSAMVAG-----
                                                                                      

Mb2186c|M.bovis_AF2122/97           ---------GQNGGPGG---------------------------------
Rv1396c|M.tuberculosis_H37Rv        ---------GQAGGAGG---------------------------------
MUL_3672|M.ulcerans_Agy99           ------------ATVGR---------------------------------
MMAR_3729|M.marinum_M               ------------ATVGG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu      -----------VDVVGG---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      Q--------RNTTNINDS--------------------------------
MAV_4827|M.avium_104                -------LEKLESLPGG---------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           --LLYGNGGNGGAGDTAN---------------------------PNGGN
Rv1396c|M.tuberculosis_H37Rv        --ILYGNGGNGGSGATG----------------------------QAGGA
MUL_3672|M.ulcerans_Agy99           ------IGTPGGAGG---------------------------LLYGNGGR
MMAR_3729|M.marinum_M               ------IGTPGGAGG---------------------------LLYGNGGR
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu      -------NPDGGTPG------------------------------AHGES
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --FNTDRSTNIGSGNTTNTEIGSHN------------------QANIGTS
MAV_4827|M.avium_104                -LLLVGSGVDVAPLKQVLQTTT---------------------FLDVSVA
                                                                                      

Mb2186c|M.bovis_AF2122/97           GGSAGLIGNGGAGG------------------------------------
Rv1396c|M.tuberculosis_H37Rv        GGAAGLIGHGGAGG------------------------------------
MUL_3672|M.ulcerans_Agy99           GGDSTLAGVSG---------------------------------------
MMAR_3729|M.marinum_M               GGDSTLAGVSG---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu      HTPGVYTDRQ----------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TSAGGSAAVGGNAG------------------------------------
MAV_4827|M.avium_104                EEPETALARGAALA------------------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           -------------AGAATGAGGAGGNGGWLYGNGG---------------
Rv1396c|M.tuberculosis_H37Rv        -------------LGGTGASGGAGGAGGWLWGNGG---------------
MUL_3672|M.ulcerans_Agy99           ---------------GGGGYAGLIG-NGGAGGTGG---------------
MMAR_3729|M.marinum_M               ---------------GGGGDAGLIG-NGGAGGTGG---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu      ---------------GEDGEDGTGTGIGGRGGNGG---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------LAGNAGLAGNAGLAGNAGLAGN---------------
MAV_4827|M.avium_104                -------------AANAPLFASSTAALAYAQDPGTG--------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           --PGGAAGLGTAG---GVSPAGGAGGAAGLWGHG-GAGGAGG------SA
Rv1396c|M.tuberculosis_H37Rv        --AGGNGGVGVAGDPGGVGGAGGAGGAAGLWGSG-GSGGTGGQGGVGGGK
MUL_3672|M.ulcerans_Agy99           --NGGSGGLGGNAWLLGSGGTGGTGGAGVSSGFG-GTGGNGGLGGLLYGS
MMAR_3729|M.marinum_M               --NGGSGGLGGNAWLLGSGGTGGTGGAGVSSGFG-GTGGNGGLGGLLYGS
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG-GK
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG-GK
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG-GR
TH_3810|M.thermoresistible__bu      -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNG-GH
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA-GNAGLAGNAGLAGNA
MAV_4827|M.avium_104                --AVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPE
                                                                                      

Mb2186c|M.bovis_AF2122/97           SGAPGAGGAGGDG------GRGGLLYGDGGAG---------GAGGNGSNG
Rv1396c|M.tuberculosis_H37Rv        SGDGGTGGIGGAG------GGGGWLHGDGGAG---------GHGGQGGTG
MUL_3672|M.ulcerans_Agy99           GGAGGTGGAGAAG------AVLGGMGGLGGDAR------LFGTGGAGGTG
MMAR_3729|M.marinum_M               GGAGGTGGAGAAG------AVLGGMGGLGGDAR------LFGTGGAGGTG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
TH_3810|M.thermoresistible__bu      GGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAG-----LAGNAGLAGNAGLAG--------NAGLAGNAG
MAV_4827|M.avium_104                DSEPRRRPVLLVG------SGLAVVGISAVLALEIALAIGIRTTGTVALQ
                                                                                      

Mb2186c|M.bovis_AF2122/97           VTG-----------------------------------------------
Rv1396c|M.tuberculosis_H37Rv        VSSG-----------GNGGAGGTGGDGRGLSGSGGAGGRGGQ-----TGV
MUL_3672|M.ulcerans_Agy99           GDN-------------SLGLTGQGG-------------------------
MMAR_3729|M.marinum_M               GDN-------------SLGLTGQGG-------------------------
Mflv_5091|M.gilvum_PYR-GCK          GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1       GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155      GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
TH_3810|M.thermoresistible__bu      GDG---------------GNGGSAG-------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAG-------------NAGLAGNAG-------------------------
MAV_4827|M.avium_104                PTPNQHLIVPTEQAPAPPPVQASAPQ------------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           -------VHGGNGGAGGAAGLIGNGG------------------------
Rv1396c|M.tuberculosis_H37Rv        GGKVGENNFGGAGGAGGTGGLIGNGG------------------------
MUL_3672|M.ulcerans_Agy99           --------QGGD--------------------------------------
MMAR_3729|M.marinum_M               --------QGGDGGYGGALFGSGGSGGG---------------------G
Mflv_5091|M.gilvum_PYR-GCK          --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1       --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155      GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
TH_3810|M.thermoresistible__bu      --------RGGTGGLRGVFGINGGNG------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------LAGNAAVAGNAAVAGNAA------------------------
MAV_4827|M.avium_104                ------PKISVPEPVAAPKPLSPPVAAP--------------------LP
                                                                                      

Mb2186c|M.bovis_AF2122/97           AGGDGGNGGLSNTGASG---------GAGGAG---------GAALIGNGG
Rv1396c|M.tuberculosis_H37Rv        AGGNGGQGAISGAGGAGGNAWLIGDGGAGGNG---------GDIRGQGGG
MUL_3672|M.ulcerans_Agy99           ---------AGAGGASG---------YGIGNG--------GAGGAAGDGG
MMAR_3729|M.marinum_M               GAGSSAGGDGGAGGASG---------YGIGNG--------GAGGAAGDGG
Mflv_5091|M.gilvum_PYR-GCK          QGGTGGTGGQGGTGGTG---------GTGGTG--------GTGGAGGDGG
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTGGQGGTGGTG---------GTGGTG--------GTGGAGGDGG
MSMEG_0868|M.smegmatis_MC2_155      HGGSGINGGHGGNGGQG---------TIEANGPSAVASGIGAGGNGGDGI
TH_3810|M.thermoresistible__bu      RAGLGGRGXXXXGGGVG---------AAVRSG---------------NGV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VAGNAAVGGVLNTGVSG---------AIGGSSHVGGAINESLGGSGSVGG
MAV_4827|M.avium_104                AAPPPAAPPLPEAPPIP---------AAPPVVPVPVVVPPVPVPVPVRIP
                                                                                      

Mb2186c|M.bovis_AF2122/97           DGGHGGNG----GHGNSGGAG----------GAGGAGG------------
Rv1396c|M.tuberculosis_H37Rv        AGGAGGAGGQLIGNGGTGGAGGTVTSPNGLGGAGGAGG------------
MUL_3672|M.ulcerans_Agy99           GAGSLGTG----GNGGSGGRAALLYGVGRDGGAGGAGG------------
MMAR_3729|M.marinum_M               GAGSLGTG----GNGGSGGRAALLYGVGGDGGAGGAGG------------
Mflv_5091|M.gilvum_PYR-GCK          LGGLGGFG----GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGL
Mvan_1264|M.vanbaalenii_PYR-1       LGGLGGFG----GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGL
MSMEG_0868|M.smegmatis_MC2_155      DGGLGGNG----GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGN
TH_3810|M.thermoresistible__bu      FSGGGGTP----SAGFGVPTTIQFPAGSCTSRAVSREG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      STAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSG------------
MAV_4827|M.avium_104                VPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVG------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           ---------HVGLIGNGGNGGAGGNG------------------------
Rv1396c|M.tuberculosis_H37Rv        ---------SAGLIGHGGTGGAGGHS------------------------
MUL_3672|M.ulcerans_Agy99           -----------DGVGSAGGSGGLGG-------------------------
MMAR_3729|M.marinum_M               -----------DVVGSAGGSGGFGG-------------------------
Mflv_5091|M.gilvum_PYR-GCK          FG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGAT
Mvan_1264|M.vanbaalenii_PYR-1       FG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGAT
MSMEG_0868|M.smegmatis_MC2_155      GGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTT
TH_3810|M.thermoresistible__bu      ------------IMPSSRAASARAG-------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------SVGGSTAVGGGAHTGVGGGVS-----------------------
MAV_4827|M.avium_104                --------GTVPQSPPQHQTPPGEGTPPK---------------------
                                                                                      

Mb2186c|M.bovis_AF2122/97           --GNDNSSTLADAGSGGAGAAGGNGG-------------LFYGNGGVGGR
Rv1396c|M.tuberculosis_H37Rv        --AQGPD---GNGGIGGAGGAGGNGG-------------QLYGTGGTGGT
MUL_3672|M.ulcerans_Agy99           --AAGLVDVGGDGGAGGAGGGAGGDG-----------------GAGAYLI
MMAR_3729|M.marinum_M               --AAGLVGVGGDGGAGGAGGGAGGDG-----------------GAGAYLI
Mflv_5091|M.gilvum_PYR-GCK          G-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA
Mvan_1264|M.vanbaalenii_PYR-1       G-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA
MSMEG_0868|M.smegmatis_MC2_155      GVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGA
TH_3810|M.thermoresistible__bu      --AACASSTSRSRRSFCCSRA-----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -TGVGVGSHVGGGISESLGGSGSVGG------------STAVGGGAHTGV
MAV_4827|M.avium_104                --PDGPGNYGGGHVPTPGAGGSGGSG------------GGHVPTPGAGGS
                                                                                      

Mb2186c|M.bovis_AF2122/97           GGNGGQAP----TPGNAGDGGAGG--------NARLIGDGGRGGNGGEGG
Rv1396c|M.tuberculosis_H37Rv        GGKGGDGFGVFGKGGAGGTGGRGG--------AAGLIGDAGTGGTGGKGG
MUL_3672|M.ulcerans_Agy99           GDGGDGGAGGH----------------------GGDGGAGGDGNAGSLAG
MMAR_3729|M.marinum_M               GDGGDGGAG-------------------------------GDGNAGSLAG
Mflv_5091|M.gilvum_PYR-GCK          -NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-ING
Mvan_1264|M.vanbaalenii_PYR-1       -NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-ING
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGGVNTGVGVGSHVGGGISESLGGS-----GSVGGSTAVGGGAHTSAIND
MAV_4827|M.avium_104                GGSGGGHVPTPGTGGPGGTGGSGG----------GHVPTPGAGTPGGSGG
                                                                                      

Mb2186c|M.bovis_AF2122/97           -DGPPGV---------------KGDGGNGGNGGNAVVIG-----NGGNGG
Rv1396c|M.tuberculosis_H37Rv        TAGEDGT---------------GGNGGTGGNGGAAVLIG-----NGGGGG
MUL_3672|M.ulcerans_Agy99           GTGGNGG--------------DAKVIGNGGNGG-----------DGGVRF
MMAR_3729|M.marinum_M               GTGGNGG--------------DAKLIGNGGNGG-----------DGGVGF
Mflv_5091|M.gilvum_PYR-GCK          GAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGG
Mvan_1264|M.vanbaalenii_PYR-1       GAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGG
MSMEG_0868|M.smegmatis_MC2_155      GDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ALGGSGS-----------VGGSTAVGGGAHTSAINESMNSSINASHSSSM
MAV_4827|M.avium_104                GHLPFPG-----------AGSTPGGSGGGHLPTPGAGTPGGGLGGFGGGH
                                                                                      

Mb2186c|M.bovis_AF2122/97           AGGFG------IP--VGSGGAGGSRGVLFGTPGANGADG-----
Rv1396c|M.tuberculosis_H37Rv        AGGNGGAGNDGTPGNGGGGGVGGTGGTLFGQPGQPGPPGQPGPA
MUL_3672|M.ulcerans_Agy99           GGGANGS-----------GGTGGAAGLL-GSPGSDGTTV-----
MMAR_3729|M.marinum_M               GGGANGS-----------GGTGGAAGLL-GSPGSDGTTV-----
Mflv_5091|M.gilvum_PYR-GCK          GGGAGGSGAGGAG---GAGGSGGSGGSG-GSGGSGGAAGDSDD-
Mvan_1264|M.vanbaalenii_PYR-1       SGGAGGSGTGGAG---GAGGSGGSGGSG-GAGGSGGAAGDSD--
MSMEG_0868|M.smegmatis_MC2_155      NGGTGGTTAGGSGN-GGNGGNGGNGGAD-GTPGTAGTTGANNP-
TH_3810|M.thermoresistible__bu      --------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH--
MAV_4827|M.avium_104                APAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK--