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MAYVIADLEAMAAAAADLAGVNSAIAAANGIAAVPTTAVQACAGDQVSAAVAALFAAHAQGYQSISTQMS AMHDQLVQTLSASSASYAGAEASNAAQASLDLINAPTQALLGRPLIGNGADGATVGRIGTPGGAGGLLYG NGGRGGDSTLAGVSGGGGGYAGLIGNGGAGGTGGNGGSGGLGGNAWLLGSGGTGGTGGAGVSSGFGGTGG NGGLGGLLYGSGGAGGTGGAGAAGAVLGGMGGLGGDARLFGTGGAGGTGGDNSLGLTGQGGQGGDAGAGG ASGYGIGNGGAGGAAGDGGGAGSLGTGGNGGSGGRAALLYGVGRDGGAGGAGGDGVGSAGGSGGLGGAAG LVDVGGDGGAGGAGGGAGGDGGAGAYLIGDGGDGGAGGHGGDGGAGGDGNAGSLAGGTGGNGGDAKVIGN GGNGGDGGVRFGGGANGSGGTGGAAGLLGSPGSDGTTV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_3672 | - | - | 100% (458) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_3247 | - | e-121 | 48.72% (548) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_3056 | - | e-119 | 50.38% (532) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2186c | PE_PGRS38 | 1e-128 | 52.52% (497) | hypothetical protein Mb2186c |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-81 | 44.49% (463) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1396c | PE_PGRS25 | 1e-127 | 52.54% (512) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 6e-13 | 38.04% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 9e-43 | 37.72% (334) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_3729 | - | 0.0 | 90.50% (484) | PE-PGRS family protein, PE_PGRS25 |
M. avium 104 | MAV_4827 | - | 4e-23 | 41.67% (180) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-64 | 41.65% (425) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-41 | 42.23% (296) | PUTATIVE - |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-80 | 43.32% (464) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv1396c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- MMAR_3729|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv1396c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- MMAR_3729|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv1396c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- MMAR_3729|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv1396c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- MMAR_3729|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------MSI MAV_4827|M.avium_104 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv1396c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- MMAR_3729|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 IDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVA MAV_4827|M.avium_104 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 ------------------MSFVIAAPEVMAAAAT------------DLAN Rv1396c|M.tuberculosis_H37Rv ------------------MSFLFAQPEMLGAAAT------------DLAS MUL_3672|M.ulcerans_Agy99 ------------------MAYVIADLEAMAAAAA------------DLAG MMAR_3729|M.marinum_M ------------------MAYVIADLEAMAAAAA------------DLAG Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MLBr_01183|M.leprae_Br4923 -----------------MPLFLNAEPQALTAAAN------------TLEG MAB_4284c|M.abscessus_ATCC_199 SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFL MAV_4827|M.avium_104 -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAA Mb2186c|M.bovis_AF2122/97 IGSSISAASAAAAGPTMGILAAGADEVSVAISALFGSHAQGYQTLSAQLA Rv1396c|M.tuberculosis_H37Rv IGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQTYQALRTQAA MUL_3672|M.ulcerans_Agy99 VNSAIAAANGIAAVPTTAVQACAGDQVSAAVAALFAAHAQGYQSISTQMS MMAR_3729|M.marinum_M VNSAIAAANGIAAVPTTAVQACAGDQVSAAVAALFAAHAQGYQSISAQMS Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG MLBr_01183|M.leprae_Br4923 LSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGA MAB_4284c|M.abscessus_ATCC_199 SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTT MAV_4827|M.avium_104 TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARR Mb2186c|M.bovis_AF2122/97 AYHN----------------QFVRALNAGAGSYAS--------------- Rv1396c|M.tuberculosis_H37Rv AFHQ----------------QIVQTLTSTAGAYAS--------------- MUL_3672|M.ulcerans_Agy99 AMHD----------------QLVQTLSASSASYAG--------------- MMAR_3729|M.marinum_M AMHD----------------QLVQTLSASSASYAG--------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MLBr_01183|M.leprae_Br4923 TNHQ----------------DLIQSLLTSSSAYAG--------------- MAB_4284c|M.abscessus_ATCC_199 AIGDG----------------AVAVGGSNSGPIAS--------------- MAV_4827|M.avium_104 IDNVMLVS----------AFLAAAALAQNVGGAMG--------------- . . Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv1396c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- MMAR_3729|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------ Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------ MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 ------------AEAANVQQTLLNAIN----------------------A Rv1396c|M.tuberculosis_H37Rv ------------AEAANVEQQLLGAIN----------------------A MUL_3672|M.ulcerans_Agy99 ------------AEASNAAQASLDLIN----------------------A MMAR_3729|M.marinum_M ------------AEASNAAQAFLDLIN----------------------A Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF MLBr_01183|M.leprae_Br4923 --------------TETANHDSL--------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------GQGSTAVNGDVRDSN----------IINADHGSNVGVD MAV_4827|M.avium_104 ----YERTAVLLVEPDTATLAVVETSD------------------GSIPD Mb2186c|M.bovis_AF2122/97 PTQTLLGRPLIG---------------------NGADGGP---------- Rv1396c|M.tuberculosis_H37Rv PTMALLGRPLIG---------------------HGADGAPGT-------- MUL_3672|M.ulcerans_Agy99 PTQALLGRPLIG---------------------NGADG------------ MMAR_3729|M.marinum_M PTQALLGRPLIG---------------------NGADG------------ Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY TH_3810|M.thermoresistible__bu SLFNLGGAGGWG--------------------GSGVDG------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTN------------------VSGHGSADIDKSVTVVDDHS MAV_4827|M.avium_104 VYKQQIRAESYG---------------------DAAGQLSAMVAG----- Mb2186c|M.bovis_AF2122/97 ---------GQNGGPGG--------------------------------- Rv1396c|M.tuberculosis_H37Rv ---------GQAGGAGG--------------------------------- MUL_3672|M.ulcerans_Agy99 ------------ATVGR--------------------------------- MMAR_3729|M.marinum_M ------------ATVGG--------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG----------- Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG----------- MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA TH_3810|M.thermoresistible__bu -----------VDVVGG--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 Q--------RNTTNINDS-------------------------------- MAV_4827|M.avium_104 -------LEKLESLPGG--------------------------------- Mb2186c|M.bovis_AF2122/97 --LLYGNGGNGGAGDTAN---------------------------PNGGN Rv1396c|M.tuberculosis_H37Rv --ILYGNGGNGGSGATG----------------------------QAGGA MUL_3672|M.ulcerans_Agy99 ------IGTPGGAGG---------------------------LLYGNGGR MMAR_3729|M.marinum_M ------IGTPGGAGG---------------------------LLYGNGGR Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV TH_3810|M.thermoresistible__bu -------NPDGGTPG------------------------------AHGES MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --FNTDRSTNIGSGNTTNTEIGSHN------------------QANIGTS MAV_4827|M.avium_104 -LLLVGSGVDVAPLKQVLQTTT---------------------FLDVSVA Mb2186c|M.bovis_AF2122/97 GGSAGLIGNGGAGG------------------------------------ Rv1396c|M.tuberculosis_H37Rv GGAAGLIGHGGAGG------------------------------------ MUL_3672|M.ulcerans_Agy99 GGDSTLAGVSG--------------------------------------- MMAR_3729|M.marinum_M GGDSTLAGVSG--------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD----------- Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN----------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP TH_3810|M.thermoresistible__bu HTPGVYTDRQ---------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TSAGGSAAVGGNAG------------------------------------ MAV_4827|M.avium_104 EEPETALARGAALA------------------------------------ Mb2186c|M.bovis_AF2122/97 -------------AGAATGAGGAGGNGGWLYGNGG--------------- Rv1396c|M.tuberculosis_H37Rv -------------LGGTGASGGAGGAGGWLWGNGG--------------- MUL_3672|M.ulcerans_Agy99 ---------------GGGGYAGLIG-NGGAGGTGG--------------- MMAR_3729|M.marinum_M ---------------GGGGDAGLIG-NGGAGGTGG--------------- Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG--------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG--------------- MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGNAGLAGN--------------- MAV_4827|M.avium_104 -------------AANAPLFASSTAALAYAQDPGTG-------------- Mb2186c|M.bovis_AF2122/97 --PGGAAGLGTAG---GVSPAGGAGGAAGLWGHG-GAGGAGG------SA Rv1396c|M.tuberculosis_H37Rv --AGGNGGVGVAGDPGGVGGAGGAGGAAGLWGSG-GSGGTGGQGGVGGGK MUL_3672|M.ulcerans_Agy99 --NGGSGGLGGNAWLLGSGGTGGTGGAGVSSGFG-GTGGNGGLGGLLYGS MMAR_3729|M.marinum_M --NGGSGGLGGNAWLLGSGGTGGTGGAGVSSGFG-GTGGNGGLGGLLYGS Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG-GK Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG-GK MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG-GR TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNG-GH MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA-GNAGLAGNAGLAGNA MAV_4827|M.avium_104 --AVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPE Mb2186c|M.bovis_AF2122/97 SGAPGAGGAGGDG------GRGGLLYGDGGAG---------GAGGNGSNG Rv1396c|M.tuberculosis_H37Rv SGDGGTGGIGGAG------GGGGWLHGDGGAG---------GHGGQGGTG MUL_3672|M.ulcerans_Agy99 GGAGGTGGAGAAG------AVLGGMGGLGGDAR------LFGTGGAGGTG MMAR_3729|M.marinum_M GGAGGTGGAGAAG------AVLGGMGGLGGDAR------LFGTGGAGGTG Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG TH_3810|M.thermoresistible__bu GGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG-----LAGNAGLAGNAGLAG--------NAGLAGNAG MAV_4827|M.avium_104 DSEPRRRPVLLVG------SGLAVVGISAVLALEIALAIGIRTTGTVALQ Mb2186c|M.bovis_AF2122/97 VTG----------------------------------------------- Rv1396c|M.tuberculosis_H37Rv VSSG-----------GNGGAGGTGGDGRGLSGSGGAGGRGGQ-----TGV MUL_3672|M.ulcerans_Agy99 GDN-------------SLGLTGQGG------------------------- MMAR_3729|M.marinum_M GDN-------------SLGLTGQGG------------------------- Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG--------- Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG--------- MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI TH_3810|M.thermoresistible__bu GDG---------------GNGGSAG------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LAG-------------NAGLAGNAG------------------------- MAV_4827|M.avium_104 PTPNQHLIVPTEQAPAPPPVQASAPQ------------------------ Mb2186c|M.bovis_AF2122/97 -------VHGGNGGAGGAAGLIGNGG------------------------ Rv1396c|M.tuberculosis_H37Rv GGKVGENNFGGAGGAGGTGGLIGNGG------------------------ MUL_3672|M.ulcerans_Agy99 --------QGGD-------------------------------------- MMAR_3729|M.marinum_M --------QGGDGGYGGALFGSGGSGGG---------------------G Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG-----------------------G MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG TH_3810|M.thermoresistible__bu --------RGGTGGLRGVFGINGGNG------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------LAGNAAVAGNAAVAGNAA------------------------ MAV_4827|M.avium_104 ------PKISVPEPVAAPKPLSPPVAAP--------------------LP Mb2186c|M.bovis_AF2122/97 AGGDGGNGGLSNTGASG---------GAGGAG---------GAALIGNGG Rv1396c|M.tuberculosis_H37Rv AGGNGGQGAISGAGGAGGNAWLIGDGGAGGNG---------GDIRGQGGG MUL_3672|M.ulcerans_Agy99 ---------AGAGGASG---------YGIGNG--------GAGGAAGDGG MMAR_3729|M.marinum_M GAGSSAGGDGGAGGASG---------YGIGNG--------GAGGAAGDGG Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTG---------GTGGTG--------GTGGAGGDGG Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGQGGTGGTG---------GTGGTG--------GTGGAGGDGG MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQG---------TIEANGPSAVASGIGAGGNGGDGI TH_3810|M.thermoresistible__bu RAGLGGRGXXXXGGGVG---------AAVRSG---------------NGV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VAGNAAVGGVLNTGVSG---------AIGGSSHVGGAINESLGGSGSVGG MAV_4827|M.avium_104 AAPPPAAPPLPEAPPIP---------AAPPVVPVPVVVPPVPVPVPVRIP Mb2186c|M.bovis_AF2122/97 DGGHGGNG----GHGNSGGAG----------GAGGAGG------------ Rv1396c|M.tuberculosis_H37Rv AGGAGGAGGQLIGNGGTGGAGGTVTSPNGLGGAGGAGG------------ MUL_3672|M.ulcerans_Agy99 GAGSLGTG----GNGGSGGRAALLYGVGRDGGAGGAGG------------ MMAR_3729|M.marinum_M GAGSLGTG----GNGGSGGRAALLYGVGGDGGAGGAGG------------ Mflv_5091|M.gilvum_PYR-GCK LGGLGGFG----GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGL Mvan_1264|M.vanbaalenii_PYR-1 LGGLGGFG----GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGL MSMEG_0868|M.smegmatis_MC2_155 DGGLGGNG----GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGN TH_3810|M.thermoresistible__bu FSGGGGTP----SAGFGVPTTIQFPAGSCTSRAVSREG------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSG------------ MAV_4827|M.avium_104 VPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVG------------ Mb2186c|M.bovis_AF2122/97 ---------HVGLIGNGGNGGAGGNG------------------------ Rv1396c|M.tuberculosis_H37Rv ---------SAGLIGHGGTGGAGGHS------------------------ MUL_3672|M.ulcerans_Agy99 -----------DGVGSAGGSGGLGG------------------------- MMAR_3729|M.marinum_M -----------DVVGSAGGSGGFGG------------------------- Mflv_5091|M.gilvum_PYR-GCK FG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGAT Mvan_1264|M.vanbaalenii_PYR-1 FG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGAT MSMEG_0868|M.smegmatis_MC2_155 GGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTT TH_3810|M.thermoresistible__bu ------------IMPSSRAASARAG------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------SVGGSTAVGGGAHTGVGGGVS----------------------- MAV_4827|M.avium_104 --------GTVPQSPPQHQTPPGEGTPPK--------------------- Mb2186c|M.bovis_AF2122/97 --GNDNSSTLADAGSGGAGAAGGNGG-------------LFYGNGGVGGR Rv1396c|M.tuberculosis_H37Rv --AQGPD---GNGGIGGAGGAGGNGG-------------QLYGTGGTGGT MUL_3672|M.ulcerans_Agy99 --AAGLVDVGGDGGAGGAGGGAGGDG-----------------GAGAYLI MMAR_3729|M.marinum_M --AAGLVGVGGDGGAGGAGGGAGGDG-----------------GAGAYLI Mflv_5091|M.gilvum_PYR-GCK G-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA Mvan_1264|M.vanbaalenii_PYR-1 G-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA MSMEG_0868|M.smegmatis_MC2_155 GVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGA TH_3810|M.thermoresistible__bu --AACASSTSRSRRSFCCSRA----------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -TGVGVGSHVGGGISESLGGSGSVGG------------STAVGGGAHTGV MAV_4827|M.avium_104 --PDGPGNYGGGHVPTPGAGGSGGSG------------GGHVPTPGAGGS Mb2186c|M.bovis_AF2122/97 GGNGGQAP----TPGNAGDGGAGG--------NARLIGDGGRGGNGGEGG Rv1396c|M.tuberculosis_H37Rv GGKGGDGFGVFGKGGAGGTGGRGG--------AAGLIGDAGTGGTGGKGG MUL_3672|M.ulcerans_Agy99 GDGGDGGAGGH----------------------GGDGGAGGDGNAGSLAG MMAR_3729|M.marinum_M GDGGDGGAG-------------------------------GDGNAGSLAG Mflv_5091|M.gilvum_PYR-GCK -NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-ING Mvan_1264|M.vanbaalenii_PYR-1 -NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-ING MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGGVNTGVGVGSHVGGGISESLGGS-----GSVGGSTAVGGGAHTSAIND MAV_4827|M.avium_104 GGSGGGHVPTPGTGGPGGTGGSGG----------GHVPTPGAGTPGGSGG Mb2186c|M.bovis_AF2122/97 -DGPPGV---------------KGDGGNGGNGGNAVVIG-----NGGNGG Rv1396c|M.tuberculosis_H37Rv TAGEDGT---------------GGNGGTGGNGGAAVLIG-----NGGGGG MUL_3672|M.ulcerans_Agy99 GTGGNGG--------------DAKVIGNGGNGG-----------DGGVRF MMAR_3729|M.marinum_M GTGGNGG--------------DAKLIGNGGNGG-----------DGGVGF Mflv_5091|M.gilvum_PYR-GCK GAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGG Mvan_1264|M.vanbaalenii_PYR-1 GAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGG MSMEG_0868|M.smegmatis_MC2_155 GDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ALGGSGS-----------VGGSTAVGGGAHTSAINESMNSSINASHSSSM MAV_4827|M.avium_104 GHLPFPG-----------AGSTPGGSGGGHLPTPGAGTPGGGLGGFGGGH Mb2186c|M.bovis_AF2122/97 AGGFG------IP--VGSGGAGGSRGVLFGTPGANGADG----- Rv1396c|M.tuberculosis_H37Rv AGGNGGAGNDGTPGNGGGGGVGGTGGTLFGQPGQPGPPGQPGPA MUL_3672|M.ulcerans_Agy99 GGGANGS-----------GGTGGAAGLL-GSPGSDGTTV----- MMAR_3729|M.marinum_M GGGANGS-----------GGTGGAAGLL-GSPGSDGTTV----- Mflv_5091|M.gilvum_PYR-GCK GGGAGGSGAGGAG---GAGGSGGSGGSG-GSGGSGGAAGDSDD- Mvan_1264|M.vanbaalenii_PYR-1 SGGAGGSGTGGAG---GAGGSGGSGGSG-GAGGSGGAAGDSD-- MSMEG_0868|M.smegmatis_MC2_155 NGGTGGTTAGGSGN-GGNGGNGGNGGAD-GTPGTAGTTGANNP- TH_3810|M.thermoresistible__bu -------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-- MAV_4827|M.avium_104 APAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK--