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VPEDASSPVIAGGAPTGPARRSDRRPGQTIRKVLDAGLQELRESSYAGLTMRAVATRAGVSPASAYTYFP SKSALVAAVYLRFLRDLPVHTDVNETAQRRVSATLRDMAVVVADEPELTAACGAALMADDPAVKPLREQI GEEVSRRIAAALGPGWPRAVKSTLQMTFSGALMTARFVSFAEISGQLDEAVDLILGAARAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2958 | - | - | 100% (201) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0711 | - | 1e-41 | 50.00% (196) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0584 | - | 2e-09 | 26.14% (176) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0790c | - | 1e-39 | 49.47% (188) | hypothetical protein Mb0790c |
| M. gilvum PYR-GCK | Mflv_1599 | - | 1e-41 | 48.45% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0767c | - | 1e-39 | 49.47% (188) | hypothetical protein Rv0767c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1217c | - | 2e-40 | 49.72% (177) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2639 | - | 2e-85 | 80.10% (201) | hypothetical protein MMAR_2639 |
| M. smegmatis MC2 155 | MSMEG_5860 | - | 5e-43 | 48.48% (198) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1258 | - | 6e-46 | 51.26% (199) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3114 | - | 1e-73 | 84.05% (163) | hypothetical protein MUL_3114 |
| M. vanbaalenii PYR-1 | Mvan_5158 | - | 5e-41 | 50.27% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1599|M.gilvum_PYR-GCK --------------MSSDAVAALTPES------GHPPRNRRQEETFRKVL
Mvan_5158|M.vanbaalenii_PYR-1 --------------MSNDAVAQLTEEP------GNPPRNRRQEETFRKVL
MSMEG_5860|M.smegmatis_MC2_155 --------------MSSDAVAAVTPSG------GETPRNRRQEETFRKVL
TH_1258|M.thermoresistible__bu --------------VSSEAVSAITSEAGAT---GDTRRNRRQEETFRKVL
MAB_1217c|M.abscessus_ATCC_199 --------------MSSEVVVPLTEET---------PRNRRQEETIRKIV
Mb0790c|M.bovis_AF2122/97 --------------MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVL
Rv0767c|M.tuberculosis_H37Rv --------------MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVL
MMAR_2639|M.marinum_M MTLSGEPGYSYTGLVSSDNADPPDAGTGAPVP-AGRRSDRRPAQTIRKVL
MUL_3114|M.ulcerans_Agy99 --------------------------------------------------
MAV_2958|M.avium_104 --------------MPEDASSPVIAG-GAPTG-PARRSDRRPGQTIRKVL
Mflv_1599|M.gilvum_PYR-GCK AAGLEMLRESSYADLTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLNLM
Mvan_5158|M.vanbaalenii_PYR-1 AAGLEMLRESSYADLTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLSLI
MSMEG_5860|M.smegmatis_MC2_155 TAGIEMLRESSYADLTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLV
TH_1258|M.thermoresistible__bu AAGMETLRESSYADLTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLV
MAB_1217c|M.abscessus_ATCC_199 TAGREMLGETTYADMTIRGVAARAKVAPATAYTYFSSKSHLVAEIYLDLI
Mb0790c|M.bovis_AF2122/97 AAAMATLREKSYADLTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLV
Rv0767c|M.tuberculosis_H37Rv AAAMATLREKSYADLTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLV
MMAR_2639|M.marinum_M EAGLDELRATSFANLTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLL
MUL_3114|M.ulcerans_Agy99 ---MDELRATSFANLTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLL
MAV_2958|M.avium_104 DAGLQELRESSYAGLTMRAVATRAGVSPASAYTYFPSKSALVAAVYLRFL
* .::*.:*:* **:** *:**:*****.**. *:* :** ::
Mflv_1599|M.gilvum_PYR-GCK QQVDYFTDVNDSTVTRVEKTLRSMALMVADEPEVAAACTTALLSG-NDAT
Mvan_5158|M.vanbaalenii_PYR-1 TKVDYFTDVNDSTAVRVEKTLRSMALMIADEPEVAAACTTALLSG-NDAA
MSMEG_5860|M.smegmatis_MC2_155 RQVPYFTDVNDSMKTRVDKALRALTLVVADEPEVAAACTTALLGGGSDEA
TH_1258|M.thermoresistible__bu RQVPYFTDVNDPMPTRVEKALRSLALVVADEPEVAAACTTALMSG-NDPA
MAB_1217c|M.abscessus_ATCC_199 HEAPYFTDVNDTQAARVTKTLRSLALVVADEPEIATGCTTALLSN-NDEA
Mb0790c|M.bovis_AF2122/97 RQVPCVTDVNVPMPIRVTSSLRHLALVVADEPEIGAACTAALLDGGADPA
Rv0767c|M.tuberculosis_H37Rv RQVPCVTDVNVPMPIRVTSSLRHLALVVADEPEIGAACTAALLDGGADPA
MMAR_2639|M.marinum_M RDLPLHTDVNDTTKTRVSATMRDMAMVVADEPELTAACGTALMAD--DPA
MUL_3114|M.ulcerans_Agy99 RDLPLHTDVNDTTKTRVSATMRDMAMVVADEPELTAACGTALMAD--DPA
MAV_2958|M.avium_104 RDLPVHTDVNETAQRRVSATLRDMAVVVADEPELTAACGAALMAD--DPA
. **** . ** ::* :::::*****: :.* :**: . * :
Mflv_1599|M.gilvum_PYR-GCK VRSVRERIGGEIHRRIRAAVGPDPDPRTLAALEMTFFGALVNAGSGAFTY
Mvan_5158|M.vanbaalenii_PYR-1 VRTVRERIGAEIHRRIRAAVGPDPDPRTLAALEMTFFGALVNAGSGAFTY
MSMEG_5860|M.smegmatis_MC2_155 VRAVRDRIGAEIHKRIRSAVGPDADPRTVSALEMTFFGALVNAGSGAFTY
TH_1258|M.thermoresistible__bu VRKVRDRIGAEIHRRIRSAVGPGADPRLVSALEMTFFGALVHAGSGAFTY
MAB_1217c|M.abscessus_ATCC_199 VRAVRDKIGLEIHRRIRSAMGPDADPRVVSALEMTFFGALMHAGSGTFTY
Mb0790c|M.bovis_AF2122/97 VRAVRDRIGAEIHRRITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTY
Rv0767c|M.tuberculosis_H37Rv VRAVRDRIGAEIHRRITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTY
MMAR_2639|M.marinum_M VQPLRAQIGEEVARRIGAALGPGWPRSVKSTLQMTFSGALMTAR--FLSY
MUL_3114|M.ulcerans_Agy99 VQPLRTQIGEEVARRIGAALGPGWPRSVKSTLQMTFSGALMTAR--FLSY
MAV_2958|M.avium_104 VKPLREQIGEEVSRRIAAALGPGWPRAVKSTLQMTFSGALMTAR--FVSF
*: :* :** *: :** :*:**. :*:*:* ***: * .::
Mflv_1599|M.gilvum_PYR-GCK HQIADRLSYVVGLIVGDDQ---------
Mvan_5158|M.vanbaalenii_PYR-1 HQIADRLSYVVGLIVGDDK---------
MSMEG_5860|M.smegmatis_MC2_155 HQIADRLTYVVGLILGEDR---------
TH_1258|M.thermoresistible__bu HQIADRLSYVVGLILGEDQHAPTPGGDE
MAB_1217c|M.abscessus_ATCC_199 HQIADKLTFVVDLMLGKKE---------
Mb0790c|M.bovis_AF2122/97 HEIADRLGYVVGLILAGANEPSTGGSE-
Rv0767c|M.tuberculosis_H37Rv HEIADRLGYVVGLILAGANEPSTGGSE-
MMAR_2639|M.marinum_M EEIAGQLDEAVNLILGAAVA--------
MUL_3114|M.ulcerans_Agy99 EEIAGQLDEAVNLILGAAVA--------
MAV_2958|M.avium_104 AEISGQLDEAVDLILGAARAS-------
:*:.:* .*.*::.