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RVVQVANFYGPRSGGLRTAVDRLGAEYCAAGHTVFLIVPGPHPERVTLPSGVVRICLPARLIPYTGGYRA VHPGPVIALLAELRPDALEVSDRLTLRSLGPWGRRHGVSTVMISHERLDRLVGQILPVPIARAVADVANR RTAANYDAVVCTTAFAREEFDRIGATNVATVPLGVDLEQFHPRRRSAEVRRRWAAPEQSLLVHCGRLSVE KQPHRSIEAVAALRDSGIDARLVVVGEGPLRARLQRQAVRLPVEFTGYIGCRDTVADILASADVALAPGP HETFGLAALEALACGTPAVVSRTSALAEILTDDSGATADNDPHAIAHAVSTVLTRPEHQRRHSARQRAEQ FTWPRSAAGMLGALGAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3033 | - | - | 100% (368) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_3550 | - | 4e-18 | 28.61% (388) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_0978 | - | 4e-18 | 26.84% (395) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1785c | - | 1e-134 | 72.81% (331) | hypothetical protein Mb1785c |
| M. gilvum PYR-GCK | Mflv_3310 | - | 1e-172 | 84.24% (368) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv0557 | pimB | 3e-18 | 26.77% (381) | mannosyltransferase PIMB |
| M. leprae Br4923 | MLBr_01715 | - | 3e-17 | 26.55% (388) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3931c | - | 1e-17 | 27.87% (305) | glycosyl transferase |
| M. marinum M | MMAR_2629 | - | 1e-154 | 75.75% (367) | glycosyl transferase |
| M. avium 104 | MAV_2143 | - | 1e-157 | 77.38% (367) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_1113 | - | 9e-19 | 27.06% (377) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1121 | - | 2e-17 | 29.22% (308) | MANNOSYLTRANSFERASE PIMB |
| M. ulcerans Agy99 | MUL_3104 | - | 1e-150 | 75.99% (354) | glycosyl transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3033|M.vanbaalenii_PYR-1 ------------------------MRVVQVANFYGPR----SGG--LRTA
Mflv_3310|M.gilvum_PYR-GCK ------------------------MRVVQVANFYGPR----SGG--LRTA
MMAR_2629|M.marinum_M ------------------------MRVVQVANFYGPR----SGG--LRTA
MUL_3104|M.ulcerans_Agy99 ------------------------MRVVQVANFYGPR----SGG--LRTA
MAV_2143|M.avium_104 ------------------------MRVVQVANFYGPR----SGG--LRTA
Mb1785c|M.bovis_AF2122/97 ------------------------MSLTAHDGRFCSRYACCSGRQLLWTS
MSMEG_1113|M.smegmatis_MC2_155 ------------------------MRVAIVAESFLPN----VNG--VTNS
TH_1121|M.thermoresistible__bu ------------------------VRVAIVTESFLPH----VNG--VTNS
Rv0557|M.tuberculosis_H37Rv ---------------------MCGVRVAIVAESFLPQ----VNG--VSNS
MAB_3931c|M.abscessus_ATCC_199 ------------------------MRIAIVAESFLPN----VNG--VSNS
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPV---VIGG--LGRH
: : : . . :
Mvan_3033|M.vanbaalenii_PYR-1 VDRLGAEYCAAGHTVF-------LIVPGPHPER---VTLPSGVVRICLPA
Mflv_3310|M.gilvum_PYR-GCK VDRLGAEYCAAGHTVH-------LIVPGRHPET---VTLSSGVERISLPA
MMAR_2629|M.marinum_M VDRLGAEYCASGHEVF-------LIVPGAHTGQ---RRLDTGVVRISVPA
MUL_3104|M.ulcerans_Agy99 VDRLGAEYCASGHEVF-------LIVPGAHTGQ---RRLDTGVVRISLPA
MAV_2143|M.avium_104 VDRLGAEYCAHGHEVF-------LIVPGQRTER---ARLYTGVVRITLPA
Mb1785c|M.bovis_AF2122/97 LGRTPHRGGPAGRGILRQRTRGVLIVPGARTER---HLLRTGVVRITLPA
MSMEG_1113|M.smegmatis_MC2_155 VLRVIDHLRRTGHEVL-------VIAPDTPRGQPPADRIHDGVRVHRVPS
TH_1121|M.thermoresistible__bu VLRVVEHLRGTGHEVL-------VIAPDTPPGQPPAERVHDGVRIHRVPS
Rv0557|M.tuberculosis_H37Rv VVKVLEHLRRTGHEAL-------VIAPDTPPGEDRAERLHDGVRVHRVPS
MAB_3931c|M.abscessus_ATCC_199 VLRVLEHFRRTGHEAI-------VIAPDTPRGQAPAATEYAGVPVHRVPA
MLBr_01715|M.leprae_Br4923 VHHLSTALAAAGHDVVVLSRRPSGTDPCTHPTS---DEISEGVRVIAAAQ
: : *: * ** .
Mvan_3033|M.vanbaalenii_PYR-1 RLIPYTGGYRAVHPG-PVIALLA-------------ELRPDALEVSDRLT
Mflv_3310|M.gilvum_PYR-GCK RLIPCTGGYRAVLPR-PVTALLG-------------HLRPDALEVSDRLT
MMAR_2629|M.marinum_M KLIPLTGGYRAVMPG-RVRELLG-------------ALDPDAVEVSDRLT
MUL_3104|M.ulcerans_Agy99 NLIPLTGGYRAVMPG-RVRELLG-------------ALDPDAVEVSDRLT
MAV_2143|M.avium_104 RLIPFTGGYRAVLPG-PVKALLE-------------ALRPDALEVSDRLT
Mb1785c|M.bovis_AF2122/97 KHIPYTGGYRAVMPG-AVRTVLE-------------TLRPDTLEVSDRLT
MSMEG_1113|M.smegmatis_MC2_155 RMFPKITSLPLGVPRPRMIGVLR-------------GFDPDVVHLASPAL
TH_1121|M.thermoresistible__bu RMFPKITSLPLGIPRPRMIGVLR-------------GFDPDVVHLASPAL
Rv0557|M.tuberculosis_H37Rv RMFPKVTTLPLGVPTFRMLRALR-------------GFDPDVVHLASPAL
MAB_3931c|M.abscessus_ATCC_199 IMFPKVSTLPLGVPQPRMVRIFR-------------EFAPDVVHLASPFV
MLBr_01715|M.leprae_Br4923 DPHEFTFSNDMMAWTLAMGHAMIRTGLSLTRHSSDLPWRPDVVHAHDWLV
: : **.:. .
Mvan_3033|M.vanbaalenii_PYR-1 LRSLGPWGRRHGVSTVMISHERLDRLVGQILPVPIARAVADVANRRTAAN
Mflv_3310|M.gilvum_PYR-GCK LRSLGPWGRRHGVSTVMISHERLDRLVGQALPNPLARWVADAANRRTAAS
MMAR_2629|M.marinum_M LRSLGCWGRERGITTVMISHERLDRLVGQVLPHRAAQRLADFANRRTAAN
MUL_3104|M.ulcerans_Agy99 LRSLGCWGRERGITTVMISHERLDRLVGQVLPHRAAQRLADFANRRTAAN
MAV_2143|M.avium_104 LRSLGRWGRDHGVTTVMISHERLDRLVGQVLPRRAAQKFADLANARTAAD
Mb1785c|M.bovis_AF2122/97 LRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAAN
MSMEG_1113|M.smegmatis_MC2_155 LGYGGLHAARHLGVPSVAVFQTDVAGFAESYGMGVASRAAWAWTRHLHSR
TH_1121|M.thermoresistible__bu LGYGGLLAARRLRVPTVAVFQTDVAGFAASYGMGVAARAAWAWTRHLHRL
Rv0557|M.tuberculosis_H37Rv LGYGGLHAARRLGVPTVAVYQTDVPGFASSYGIPMTARAAWAWFRHLHRL
MAB_3931c|M.abscessus_ATCC_199 LGYGGLRAAQHLDVPVVAVYQTDVAGFADSYGAGFAARAAWRWTKHLHGR
MLBr_01715|M.leprae_Br4923 AHPAITLAQFYDVPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRES
. . . :
Mvan_3033|M.vanbaalenii_PYR-1 YDAVVCTTAFAREEFDRIG--ATNVATVPLGVDLEQFHPRRRSAEVRRRW
Mflv_3310|M.gilvum_PYR-GCK YDTVVCTTAFARAEFDRIG--ATNVMTVPLGVDLDQFHPRRRSWAVRRQW
MMAR_2629|M.marinum_M YDTVVCTTAFAREEFDRIG--ATNTLTVPLGVDLQTFHPRRRCPLVRQRF
MUL_3104|M.ulcerans_Agy99 YDTVVCTTAFAREEFDRIG--ATNTLTVPLGVDLQTFHPRRRCPLVRQRF
MAV_2143|M.avium_104 YDTVVCTTGFAREEFDRIG--AGNTVTVPLGVDLQTFHPRHHSQLVRRRW
Mb1785c|M.bovis_AF2122/97 YDTVVCTTGFAREEFDRIG--ATNTVTVPLGVDLKTFHPRRRCARVRQHW
MSMEG_1113|M.smegmatis_MC2_155 ADRTLAPSTSAMENLAAHR--IPRVHRWGRGVDITGFVPSARDEHLRRTW
TH_1121|M.thermoresistible__bu ADRTLAPSTAAMRDLARHG--VPRVHLWARGVDVGGFAPSARDEQLRRRW
Rv0557|M.tuberculosis_H37Rv ADRTLAPSTATMESLIAQG--IPRVHRWARGVDVQRFAPSARNEVLRRRW
MAB_3931c|M.abscessus_ATCC_199 ADRTLAPSSSAMEDLAMHG--IPRVFRWSRGVDIERFAPSARDDELRRAW
MLBr_01715|M.leprae_Br4923 DSLITCSASMCNEIIELFGPGLAEITVIRNGIDPARWPFAARR-------
. ..: : . *:* : :
Mvan_3033|M.vanbaalenii_PYR-1 AAPEQSLLVHCGRLSVEKQPHRSIEAVAALRDSGIDARLVVVGEGPLRAR
Mflv_3310|M.gilvum_PYR-GCK AGRGQVLLVHCGRLSVEKHPHRSIDATAALRRRGIDARLVVVGEGPLRGR
MMAR_2629|M.marinum_M ATPRQLLLIHCGRLSVEKHVDRSIGALAALCDAGVDARLVIVGEGPLRAR
MUL_3104|M.ulcerans_Agy99 ATPRQLLLIHCGRLSVEKHVDRSIGALAALCDAGVDARFVIVGEGPLRAR
MAV_2143|M.avium_104 AAPTQLLLVHCGRLSVEKRVDRSIDALGELCHAGVDARLVVVGEGPLRAR
Mb1785c|M.bovis_AF2122/97 ATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGPLRAR
MSMEG_1113|M.smegmatis_MC2_155 SPDGRPIVGFVGRLAPEKHVER----LAVLAAR-DDLQLVIVGDGVDRVK
TH_1121|M.thermoresistible__bu SPDGKPIVGFVGRLAPEKHVER----LRALAPR-TDLQLVIVGDGVDRRK
Rv0557|M.tuberculosis_H37Rv SPDGKPIVGFVGRLAPEKHVDR----LTGLAAS-GAVRLVIVGDGIDRAR
MAB_3931c|M.abscessus_ATCC_199 SPKGKPIIGFVGRLAPEKHVER----LAVLAGR-DDLQLVIVGGGVEREA
MLBr_01715|M.leprae_Br4923 ARTGPAELLYVGRLEYEKGVHDVIAALPRIRRSYPGTTLTIAGEGTQQDW
: : . *** ** . : :.:.* * :
Mvan_3033|M.vanbaalenii_PYR-1 LQRQAVRL----PVEFTGYIGCRDTVADILASADVALAPGPHETFGLAAL
Mflv_3310|M.gilvum_PYR-GCK LERQPARL----PVDFTGHIGCRDTVAEILASADVALAPGPHETFGLAAL
MMAR_2629|M.marinum_M LQRQAAGL----PVDFTGFVTHRDTVAQLLASADIALAPGPHETFGLAAL
MUL_3104|M.ulcerans_Agy99 LQRQAAGL----PVDFTGFVTHRDTVAQLLASADIPLAPGPHETFGLAAL
MAV_2143|M.avium_104 LQRQAARL----AVDFTGFISDRTTVAQLLASADVTLAPGPHETFGLAAL
Mb1785c|M.bovis_AF2122/97 LERKATGL----PIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAAL
MSMEG_1113|M.smegmatis_MC2_155 LQTVLP------TAVFTGELRG-AALAAAYASMDVFVHPGEHETFCQTVQ
TH_1121|M.thermoresistible__bu LENLLP------TAVFTGALYG-EQLAAAYASMDVFVHPGEHETFCQAVQ
Rv0557|M.tuberculosis_H37Rv LQSAMP------TAVFTGARYG-KELAEAYASMDVFVHSGEHETFCQVVQ
MAB_3931c|M.abscessus_ATCC_199 LEKLMP------TAVFTGELTG-SALSRAYASLDVFIHPGEHETFCQAVQ
MLBr_01715|M.leprae_Br4923 LVDQARKYKVIKATRFVGHLNH-NELLAALQRADAAVLPSHYEPFGLVAL
* . *.* : * : .. :*.* ..
Mvan_3033|M.vanbaalenii_PYR-1 EALACGTPAVVSRTSALAEILTDDSG---ATADNDPHAIAHAVSTVLTRP
Mflv_3310|M.gilvum_PYR-GCK EALASGTPAVVSRTSALAEILTRDSG---ATADNDPDAVAEAVAGVLTRP
MMAR_2629|M.marinum_M ESLACGTPAVVSRTSALSEIITTDSG---ASADNDPAAIAAAVRTIVGWP
MUL_3104|M.ulcerans_Agy99 ESLACGTPAVVSRTSALSEIITTDSG---ASADNDPAAIAAAVRTIVGWP
MAV_2143|M.avium_104 ESLACGTPAVVSRTSALTEIVTPDSG---ASAANDPAAIARAVSAIVSRP
Mb1785c|M.bovis_AF2122/97 ESLACGTPAVVSRTSALTEIITADSG---ACADNRPEAIAHAVRTIVSRP
MSMEG_1113|M.smegmatis_MC2_155 EAMASGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPAAVTHLIA--
TH_1121|M.thermoresistible__bu EALASGLPVIAPDAGGPRDLVAPCRTGLLLPVEEFETRLAGAVDHLLA--
Rv0557|M.tuberculosis_H37Rv EALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPDAVAHLVH--
MAB_3931c|M.abscessus_ATCC_199 EALASGVPSIAPDAGGPRDLVIPGRNGMLLPVADFEARLGMAVDHLVQPA
MLBr_01715|M.leprae_Br4923 EAAAAGTPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTVLEDPD
*: *.* * :.. .. : : . :
Mvan_3033|M.vanbaalenii_PYR-1 EHQRR-HSARQ-RAEQFTWPRSAAGMLGALG-------AR----------
Mflv_3310|M.gilvum_PYR-GCK EAQRR-DCARR-RAEQFTWPSSAAGMLRVMQ-------NR----------
MMAR_2629|M.marinum_M ERQRR-SSARR-RAEMFTWQVAAAGMLTALDADAPGCCGGGDAASRAC--
MUL_3104|M.ulcerans_Agy99 ERQRR-SSARR-RAEMFTWQGWPP----------PGC-------------
MAV_2143|M.avium_104 ERQRR-ISARR-RAEDFTWHRAAAGMLASLR--APVFDDPGGDSEQTA--
Mb1785c|M.bovis_AF2122/97 ERHRR-RCARR-RAEIFTWQRAAASMLATLG--AMAVSTRCGDTQDTA--
MSMEG_1113|M.smegmatis_MC2_155 ERRRYGIAARR-SVLARTWPVVCDELIGHYEAVLGRRSLRAA--------
TH_1121|M.thermoresistible__bu ERPRYAVAARR-SVLGRTWPAICDQLLEHYAAVXXAVAHPAPHRHAG---
Rv0557|M.tuberculosis_H37Rv ERQRYALAARR-SVLGRSWPVVCDELLGHYEAVRGRRTTQAA--------
MAB_3931c|M.abscessus_ATCC_199 TRSRFSAAARR-GVLARTWPAICDELLEHYAAAAGTTLGRGIMTA-----
MLBr_01715|M.leprae_Br4923 AAQQRALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQPRLPIVEHA
: .**. . *
Mvan_3033|M.vanbaalenii_PYR-1 ----
Mflv_3310|M.gilvum_PYR-GCK ----
MMAR_2629|M.marinum_M ----
MUL_3104|M.ulcerans_Agy99 ----
MAV_2143|M.avium_104 ----
Mb1785c|M.bovis_AF2122/97 ----
MSMEG_1113|M.smegmatis_MC2_155 ----
TH_1121|M.thermoresistible__bu ----
Rv0557|M.tuberculosis_H37Rv ----
MAB_3931c|M.abscessus_ATCC_199 ----
MLBr_01715|M.leprae_Br4923 LPDR