For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RVVQVANFYGPRSGGLRTAVDRLGAEYCAAGHTVHLIVPGRHPETVTLSSGVERISLPARLIPCTGGYRA VLPRPVTALLGHLRPDALEVSDRLTLRSLGPWGRRHGVSTVMISHERLDRLVGQALPNPLARWVADAANR RTAASYDTVVCTTAFARAEFDRIGATNVMTVPLGVDLDQFHPRRRSWAVRRQWAGRGQVLLVHCGRLSVE KHPHRSIDATAALRRRGIDARLVVVGEGPLRGRLERQPARLPVDFTGHIGCRDTVAEILASADVALAPGP HETFGLAALEALASGTPAVVSRTSALAEILTRDSGATADNDPDAVAEAVAGVLTRPEAQRRDCARRRAEQ FTWPSSAAGMLRVMQNR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3310 | - | - | 100% (368) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_4262 | - | 7e-20 | 28.40% (405) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_5260 | - | 1e-18 | 28.85% (305) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1785c | - | 1e-124 | 69.60% (329) | hypothetical protein Mb1785c |
| M. tuberculosis H37Rv | Rv3032 | - | 2e-19 | 28.36% (409) | transferase |
| M. leprae Br4923 | MLBr_01715 | - | 3e-18 | 27.62% (391) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3931c | - | 8e-20 | 27.76% (371) | glycosyl transferase |
| M. marinum M | MMAR_2629 | - | 1e-147 | 73.15% (365) | glycosyl transferase |
| M. avium 104 | MAV_2143 | - | 1e-148 | 75.14% (362) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_1113 | - | 9e-19 | 28.14% (366) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1121 | - | 5e-20 | 30.84% (308) | MANNOSYLTRANSFERASE PIMB |
| M. ulcerans Agy99 | MUL_3104 | - | 1e-144 | 73.73% (354) | glycosyl transferase |
| M. vanbaalenii PYR-1 | Mvan_3033 | - | 1e-172 | 84.24% (368) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3032|M.tuberculosis_H37Rv ------------------------MRILMVSWEYPPV---VIGG--LGRH
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPV---VIGG--LGRH
Mflv_3310|M.gilvum_PYR-GCK ------------------------MRVVQVANFYGPR----SGG--LRTA
Mvan_3033|M.vanbaalenii_PYR-1 ------------------------MRVVQVANFYGPR----SGG--LRTA
MMAR_2629|M.marinum_M ------------------------MRVVQVANFYGPR----SGG--LRTA
MUL_3104|M.ulcerans_Agy99 ------------------------MRVVQVANFYGPR----SGG--LRTA
MAV_2143|M.avium_104 ------------------------MRVVQVANFYGPR----SGG--LRTA
Mb1785c|M.bovis_AF2122/97 ------------------------MSLTAHDGRFCSRYACCSGRQLLWTS
MSMEG_1113|M.smegmatis_MC2_155 ------------------------MRVAIVAESFLPN----VNG--VTNS
TH_1121|M.thermoresistible__bu ------------------------VRVAIVTESFLPH----VNG--VTNS
MAB_3931c|M.abscessus_ATCC_199 ------------------------MRIAIVAESFLPN----VNG--VSNS
: : : . . :
Rv3032|M.tuberculosis_H37Rv VHHLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPH
MLBr_01715|M.leprae_Br4923 VHHLSTALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDPH
Mflv_3310|M.gilvum_PYR-GCK VDRLGAEYCAAGHTVH-------LIVPGRHPETVTLSSGVERISLPARLI
Mvan_3033|M.vanbaalenii_PYR-1 VDRLGAEYCAAGHTVF-------LIVPGPHPERVTLPSGVVRICLPARLI
MMAR_2629|M.marinum_M VDRLGAEYCASGHEVF-------LIVPGAHTGQRRLDTGVVRISVPAKLI
MUL_3104|M.ulcerans_Agy99 VDRLGAEYCASGHEVF-------LIVPGAHTGQRRLDTGVVRISLPANLI
MAV_2143|M.avium_104 VDRLGAEYCAHGHEVF-------LIVPGQRTERARLYTGVVRITLPARLI
Mb1785c|M.bovis_AF2122/97 LGRTPHRGGPAGRGILRQRTRGVLIVPGARTERHLLRTGVVRITLPAKHI
MSMEG_1113|M.smegmatis_MC2_155 VLRVIDHLRRTGHEVLVIAP----DTPRGQPPADRIHDGVRVHRVPSRMF
TH_1121|M.thermoresistible__bu VLRVVEHLRGTGHEVLVIAP----DTPPGQPPAERVHDGVRIHRVPSRMF
MAB_3931c|M.abscessus_ATCC_199 VLRVLEHFRRTGHEAIVIAP----DTPRGQAPAATEYAGVPVHRVPAIMF
: : *: * :. ** .
Rv3032|M.tuberculosis_H37Rv EFTFGNDMMAWTLAMGHAMIRAGLRLKKLGTDRSWRPDVVHAHDWLVAHP
MLBr_01715|M.leprae_Br4923 EFTFSNDMMAWTLAMGHAMIRTGLSLTRHSSDLPWRPDVVHAHDWLVAHP
Mflv_3310|M.gilvum_PYR-GCK PCTGG--------------YRAVLPRPVTALLGHLRPDALEVSDRLTLRS
Mvan_3033|M.vanbaalenii_PYR-1 PYTGG--------------YRAVHPGPVIALLAELRPDALEVSDRLTLRS
MMAR_2629|M.marinum_M PLTGG--------------YRAVMPGRVRELLGALDPDAVEVSDRLTLRS
MUL_3104|M.ulcerans_Agy99 PLTGG--------------YRAVMPGRVRELLGALDPDAVEVSDRLTLRS
MAV_2143|M.avium_104 PFTGG--------------YRAVLPGPVKALLEALRPDALEVSDRLTLRS
Mb1785c|M.bovis_AF2122/97 PYTGG--------------YRAVMPGAVRTVLETLRPDTLEVSDRLTLRS
MSMEG_1113|M.smegmatis_MC2_155 PKITS-------------LPLGVPRPRMIGVLRGFDPDVVHLASPALLGY
TH_1121|M.thermoresistible__bu PKITS-------------LPLGIPRPRMIGVLRGFDPDVVHLASPALLGY
MAB_3931c|M.abscessus_ATCC_199 PKVST-------------LPLGVPQPRMVRIFREFAPDVVHLASPFVLGY
**.:. .
Rv3032|M.tuberculosis_H37Rv AIALAQ-FYDVPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDS
MLBr_01715|M.leprae_Br4923 AITLAQ-FYDVPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDS
Mflv_3310|M.gilvum_PYR-GCK LGPWGR-RHGVSTVMISHERLDRLVGQALPNPLARWVADAANRRTAASYD
Mvan_3033|M.vanbaalenii_PYR-1 LGPWGR-RHGVSTVMISHERLDRLVGQILPVPIARAVADVANRRTAANYD
MMAR_2629|M.marinum_M LGCWGR-ERGITTVMISHERLDRLVGQVLPHRAAQRLADFANRRTAANYD
MUL_3104|M.ulcerans_Agy99 LGCWGR-ERGITTVMISHERLDRLVGQVLPHRAAQRLADFANRRTAANYD
MAV_2143|M.avium_104 LGRWGR-DHGVTTVMISHERLDRLVGQVLPRRAAQKFADLANARTAADYD
Mb1785c|M.bovis_AF2122/97 LGRWGR-EHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYD
MSMEG_1113|M.smegmatis_MC2_155 GGLHAARHLGVPSVAVFQTDVAGFAESYGMGVASRAAWAWTRHLHS-RAD
TH_1121|M.thermoresistible__bu GGLLAARRLRVPTVAVFQTDVAGFAASYGMGVAARAAWAWTRHLHR-LAD
MAB_3931c|M.abscessus_ATCC_199 GGLRAAQHLDVPVVAVYQTDVAGFADSYGAGFAARAAWRWTKHLHG-RAD
. :. * : :: .
Rv3032|M.tuberculosis_H37Rv LITCSASMNDEITELFGPG---LAEITVIRNGIDAARWPFAARRPRTGP-
MLBr_01715|M.leprae_Br4923 LITCSASMCNEIIELFGPG---LAEITVIRNGIDPARWPFAARRARTGP-
Mflv_3310|M.gilvum_PYR-GCK TVVCTTAFARAEFDRIGATNVMTVPLGVDLDQFHPRRRSWAVRRQWAGRG
Mvan_3033|M.vanbaalenii_PYR-1 AVVCTTAFAREEFDRIGATNVATVPLGVDLEQFHPRRRSAEVRRRWAAPE
MMAR_2629|M.marinum_M TVVCTTAFAREEFDRIGATNTLTVPLGVDLQTFHPRRRCPLVRQRFATPR
MUL_3104|M.ulcerans_Agy99 TVVCTTAFAREEFDRIGATNTLTVPLGVDLQTFHPRRRCPLVRQRFATPR
MAV_2143|M.avium_104 TVVCTTGFAREEFDRIGAGNTVTVPLGVDLQTFHPRHHSQLVRRRWAAPT
Mb1785c|M.bovis_AF2122/97 TVVCTTGFAREEFDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATPT
MSMEG_1113|M.smegmatis_MC2_155 RTLAPSTSAMENLAAHRIPRVHRWGRGVDITGFVPSARDEHLRRTWSPDG
TH_1121|M.thermoresistible__bu RTLAPSTAAMRDLARHGVPRVHLWARGVDVGGFAPSARDEQLRRRWSPDG
MAB_3931c|M.abscessus_ATCC_199 RTLAPSSSAMEDLAMHGIPRVFRWSRGVDIERFAPSARDDELRRAWSPKG
..: * : . *: :
Rv3032|M.tuberculosis_H37Rv -AELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLIDQ
MLBr_01715|M.leprae_Br4923 -AELLYVGRLEYEKGVHDVIAALPRIRRSYPGTTLTIAGEGTQQDWLVDQ
Mflv_3310|M.gilvum_PYR-GCK QVLLVHCGRLSVEKHPHRSIDATAALRRRGIDARLVVVGEGPLRGRLERQ
Mvan_3033|M.vanbaalenii_PYR-1 QSLLVHCGRLSVEKQPHRSIEAVAALRDSGIDARLVVVGEGPLRARLQRQ
MMAR_2629|M.marinum_M QLLLIHCGRLSVEKHVDRSIGALAALCDAGVDARLVIVGEGPLRARLQRQ
MUL_3104|M.ulcerans_Agy99 QLLLIHCGRLSVEKHVDRSIGALAALCDAGVDARFVIVGEGPLRARLQRQ
MAV_2143|M.avium_104 QLLLVHCGRLSVEKRVDRSIDALGELCHAGVDARLVVVGEGPLRARLQRQ
Mb1785c|M.bovis_AF2122/97 QILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGPLRARLERK
MSMEG_1113|M.smegmatis_MC2_155 RPIVGFVGRLAPEKHVERLAVLAARD-----DLQLVIVGDGVDRVKLQTV
TH_1121|M.thermoresistible__bu KPIVGFVGRLAPEKHVERLRALAPRT-----DLQLVIVGDGVDRRKLENL
MAB_3931c|M.abscessus_ATCC_199 KPIIGFVGRLAPEKHVERLAVLAGRD-----DLQLVIVGGGVEREALEKL
: . *** ** . . :.:.* * : *
Rv3032|M.tuberculosis_H37Rv ARKHRVLRATRFVGHLDHTELLALLHR-ADAAVLPSHYEPFGLVALEAAA
MLBr_01715|M.leprae_Br4923 ARKYKVIKATRFVGHLNHNELLAALQR-ADAAVLPSHYEPFGLVALEAAA
Mflv_3310|M.gilvum_PYR-GCK P----ARLPVDFTGHIGCRDTVAEILASADVALAPGPHETFGLAALEALA
Mvan_3033|M.vanbaalenii_PYR-1 A----VRLPVEFTGYIGCRDTVADILASADVALAPGPHETFGLAALEALA
MMAR_2629|M.marinum_M A----AGLPVDFTGFVTHRDTVAQLLASADIALAPGPHETFGLAALESLA
MUL_3104|M.ulcerans_Agy99 A----AGLPVDFTGFVTHRDTVAQLLASADIPLAPGPHETFGLAALESLA
MAV_2143|M.avium_104 A----ARLAVDFTGFISDRTTVAQLLASADVTLAPGPHETFGLAALESLA
Mb1785c|M.bovis_AF2122/97 A----TGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLA
MSMEG_1113|M.smegmatis_MC2_155 LP------TAVFTGELRG-AALAAAYASMDVFVHPGEHETFCQTVQEAMA
TH_1121|M.thermoresistible__bu LP------TAVFTGALYG-EQLAAAYASMDVFVHPGEHETFCQAVQEALA
MAB_3931c|M.abscessus_ATCC_199 MP------TAVFTGELTG-SALSRAYASLDVFIHPGEHETFCQAVQEALA
. *.* : :: * : *. :*.* .. *: *
Rv3032|M.tuberculosis_H37Rv AGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPAAAQR
MLBr_01715|M.leprae_Br4923 AGTPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTVLEDPDAAQQ
Mflv_3310|M.gilvum_PYR-GCK SGTPAVVSRTSALAEILTRDSG--ATADNDPDAVAEAVAGVLTRP---EA
Mvan_3033|M.vanbaalenii_PYR-1 CGTPAVVSRTSALAEILTDDSG--ATADNDPHAIAHAVSTVLTRP---EH
MMAR_2629|M.marinum_M CGTPAVVSRTSALSEIITTDSG--ASADNDPAAIAAAVRTIVGWP---ER
MUL_3104|M.ulcerans_Agy99 CGTPAVVSRTSALSEIITTDSG--ASADNDPAAIAAAVRTIVGWP---ER
MAV_2143|M.avium_104 CGTPAVVSRTSALTEIVTPDSG--ASAANDPAAIARAVSAIVSRP---ER
Mb1785c|M.bovis_AF2122/97 CGTPAVVSRTSALTEIITADSG--ACADNRPEAIAHAVRTIVSRP---ER
MSMEG_1113|M.smegmatis_MC2_155 SGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPAAVTHLI---AERR
TH_1121|M.thermoresistible__bu SGLPVIAPDAGGPRDLVAPCRTGLLLPVEEFETRLAGAVDHLL---AERP
MAB_3931c|M.abscessus_ATCC_199 SGVPSIAPDAGGPRDLVIPGRNGMLLPVADFEARLGMAVDHLVQP-ATRS
.* * :.. .. : : . : .
Rv3032|M.tuberculosis_H37Rv RARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHALPDR
MLBr_01715|M.leprae_Br4923 RALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQPRLPIVEHALPDR
Mflv_3310|M.gilvum_PYR-GCK QRRDCARRRAEQFTWPSSAAGMLRVMQ-------NR--------------
Mvan_3033|M.vanbaalenii_PYR-1 QRRHSARQRAEQFTWPRSAAGMLGALG-------AR--------------
MMAR_2629|M.marinum_M QRRSSARRRAEMFTWQVAAAGMLTALDADAPGCCGGGDAASRAC------
MUL_3104|M.ulcerans_Agy99 QRRSSARRRAEMFTWQGWPP----------PGC-----------------
MAV_2143|M.avium_104 QRRISARRRAEDFTWHRAAAGMLASLR--APVFDDPGGDSEQTA------
Mb1785c|M.bovis_AF2122/97 HRRRCARRRAEIFTWQRAAASMLATLG--AMAVSTRCGDTQDTA------
MSMEG_1113|M.smegmatis_MC2_155 RYGIAARRSVLARTWPVVCDELIGHYEAVLGRRSLRAA------------
TH_1121|M.thermoresistible__bu RYAVAARRSVLGRTWPAICDQLLEHYAAVXXAVAHPAPHRHAG-------
MAB_3931c|M.abscessus_ATCC_199 RFSAAARRGVLARTWPAICDELLEHYAAAAGTTLGRGIMTA---------
: . .: . *