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KRILLVTNDYPPRRGGIQAYLEALVEHLVASGEHSLTVYAPKWKGAEDYDSVAAATGYEVVRHPGTLMVP EPTVALRMRRLIRERGIDTVWFGAAAPLALLAPLARAAGARRVIASTHGHEVGWSMLPLARTALRRIGND TDVVTFISAYTRGRFASAFGPHAALEHVPPGVDTDRFVPDEVARAELRARYGLGERPVVVCVSRLVPRKG QDMLIRALPAIRQRVPGAALVIVGGGPYRTALHRLAHTFGVAEDVVFTDGVPGEELPAHHAMADVFAMPC RTRGSGLDVEGLGIVYLEASSTGVPVVAGRSGGAPETVVDGETGVVVDGWDVGAIAAAVGDLLADPARAA AMGAAGRQAVLDNWRWSRQAEKLARLL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3550 | - | - | 100% (378) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_2096 | - | 9e-24 | 29.32% (399) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_5246 | - | 6e-23 | 29.17% (360) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2211c | - | 1e-152 | 70.11% (378) | hypothetical protein Mb2211c |
| M. gilvum PYR-GCK | Mflv_2961 | - | 0.0 | 90.74% (378) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv2188c | - | 1e-152 | 70.11% (378) | hypothetical protein Rv2188c |
| M. leprae Br4923 | MLBr_00886 | - | 1e-147 | 67.46% (378) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_1976 | - | 1e-148 | 70.03% (377) | hypothetical protein MAB_1976 |
| M. marinum M | MMAR_3232 | - | 1e-155 | 71.96% (378) | glycosyltransferase |
| M. avium 104 | MAV_2306 | - | 1e-151 | 71.43% (378) | glycosyl transferase, group 1 |
| M. smegmatis MC2 155 | MSMEG_4253 | - | 1e-168 | 77.33% (375) | glycosyl transferase, group 1 family protein |
| M. thermoresistible (build 8) | TH_1111 | - | 1e-168 | 76.72% (378) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3543 | - | 1e-154 | 71.69% (378) | glycosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3550|M.vanbaalenii_PYR-1 --------MKRILLVTNDYPPRRGGIQAYLEALVEHLVASGEHSLTVYAP
Mflv_2961|M.gilvum_PYR-GCK ----MGGLVKRILLVTNDFPPRRGGIQSYLEALVGHLVASGDHTLTVYAP
MSMEG_4253|M.smegmatis_MC2_155 -----------MLLVTNDFPPRRGGIQSYLEAFVGELVRT--HELTVYAP
TH_1111|M.thermoresistible__bu -----VTGVSRVLLVTNDFPPRPGGIQSYLHELVLRLVRTQSHVVTVYAP
Mb2211c|M.bovis_AF2122/97 --------MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAP
Rv2188c|M.tuberculosis_H37Rv --------MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAP
MMAR_3232|M.marinum_M --------MSRVLLVTNDFPPRRGGIQSYLSEFVGRLVEAGSHSITVYAP
MUL_3543|M.ulcerans_Agy99 --------MSRVLLVTNDFPPRRGGIQSYLSESVGRLVEAGSHSITVYAP
MLBr_00886|M.leprae_Br4923 --------MSRVLLVTNDFPPRRGGIQSYLGEFVDRLINIGSHDVMVYAP
MAV_2306|M.avium_104 --------MSRVLLVTNDFPPRPGGIHSYLGEFVGRLAAAGSHELTVYAP
MAB_1976|M.abscessus_ATCC_1997 MTFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLAG--SHEVTVYAP
:******:*** ***::** * .* * : ****
Mvan_3550|M.vanbaalenii_PYR-1 KWKGAEDYDSVAAATGYEVVRHPGTLMVPEPTVALRMRRLIRERGIDTVW
Mflv_2961|M.gilvum_PYR-GCK KWKGAPDYDAVAAATGYEVVRHPGTLMLPEPTVVLRMRKIIAERGIDTVW
MSMEG_4253|M.smegmatis_MC2_155 KWKGAEEYDEKAARSGYRVVRHPTTLMLPEPTVASRMKRLIGEHDIETVW
TH_1111|M.thermoresistible__bu RWRGSDDFDAEAARTGYRVVRHPGTLMLPEPSVARRMRRLIRDEGIDTVW
Mb2211c|M.bovis_AF2122/97 QWKGADAFDDAARAAGYRVVRHPSTVMLPGPTVDVRMRRLIAEHDIETVW
Rv2188c|M.tuberculosis_H37Rv QWKGADAFDDAARAAGYRVVRHPSTVMLPGPTVDVRMRRLIAEHDIETVW
MMAR_3232|M.marinum_M QWKGAQGYDDVARAAGYRVVRHPSTLMLPVPTVDSRMRRLIAQHDIDTVW
MUL_3543|M.ulcerans_Agy99 QWKGAQGYDDVARAAGYRVVRHPSTLMLPVPTVDSRMRRLIAQHDIDTVW
MLBr_00886|M.leprae_Br4923 QWTGADTFDNAAHDGGYQVVRHPGTLMLPGPAVDARMRRLIVDHGIDTVW
MAV_2306|M.avium_104 DWKGAQAHDEAV---GYRVVRHPGTLMLPGPAVDARMRRLIAEHVIDTVW
MAB_1976|M.abscessus_ATCC_1997 RWKGCERYDAAA---EYQVVRHPTSLMLPGPGVRRRMVDLIRAQHADVVW
* *. .* . *.***** ::*:* * * ** :* . :.**
Mvan_3550|M.vanbaalenii_PYR-1 FGAAAPLALLAPLARAAGARRVIASTHGHEVGWSMLPLARTALRRIGNDT
Mflv_2961|M.gilvum_PYR-GCK FGAAAPLALMAPLARAAGARRVIASTHGHEVGWSMLPLARNALRRIGNDT
MSMEG_4253|M.smegmatis_MC2_155 FGAAAPLALLGPLARRAGARRIVASTHGHEVGWSMLPVARTALRRIGNDA
TH_1111|M.thermoresistible__bu FGAAAPLALLAGTARAAGARRVLASTHGHEVGWSMLPVARHALRIIGDNT
Mb2211c|M.bovis_AF2122/97 FGAAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGT
Rv2188c|M.tuberculosis_H37Rv FGAAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGT
MMAR_3232|M.marinum_M FGAAAPLALLAPRARQAGATRVLASTHGHEVGWSMLPVARSVLRRIGDTT
MUL_3543|M.ulcerans_Agy99 FGAAAPLALLAPRARQAGATRVLASTHGHEVGWSMLPVAGSVLRRIGDTT
MLBr_00886|M.leprae_Br4923 FGSAAPLALLAPCARKAGATRVLASTHGHEVGWSMLPVARSVLRRIGDVT
MAV_2306|M.avium_104 FGAAAPLALLAQRARAAGARRVLASTHGHEVGWSMLPVARSVLRRIGEQT
MAB_1976|M.abscessus_ATCC_1997 FGAAAPLALLSSAAKAAGAAVTAASTHGHEVGWSMLPVARSALRQIGEST
**:******:. *: *** **************:* .** **: :
Mvan_3550|M.vanbaalenii_PYR-1 DVVTFISAYTRGRFASAFGPHAALEHVPPGVDTDRFVPDEVARAELRARY
Mflv_2961|M.gilvum_PYR-GCK DVVTYISAYTRGRFASAFGPDAALEHVPPGVDTDRFVPDEVARAEMRARY
MSMEG_4253|M.smegmatis_MC2_155 DVVTFVSRYTRSRFASAFGPSAALEHLPPGVDTDRFAPDPDARARMRERY
TH_1111|M.thermoresistible__bu DVLTYVSRYTRRRFASAFGPRAGLEHVPPGVDIDRFAPDPVARTALRTRY
Mb2211c|M.bovis_AF2122/97 DVVTFVSSYTRSRFASAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
Rv2188c|M.tuberculosis_H37Rv DVVTFVSSYTRSRFASAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
MMAR_3232|M.marinum_M DIVTFVSRYTRSRFAPAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
MUL_3543|M.ulcerans_Agy99 DIVTFVSRYTRSRFAPAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
MLBr_00886|M.leprae_Br4923 DVVTFVSRYTRSRVTAAFGPRAALEYLPPGVDADRFRPDPASRAELRNRY
MAV_2306|M.avium_104 DVVTFVSRYTRSRFAPAFGPRARLEYLPSGVDTDRFRPDPAGRARLRERY
MAB_1976|M.abscessus_ATCC_1997 DVITYVSRYTRGRFASAFGPRAALEYLPSGVDTNRFCPDPAAREELRERY
*::*::* *** *.:.**** * **::*.*** :** ** .* :* **
Mvan_3550|M.vanbaalenii_PYR-1 GLGERPVVVCVSRLVPRKGQDMLIRALPAIRQRVPGAALVIVGGGPYRTA
Mflv_2961|M.gilvum_PYR-GCK RLGNRPVVACVSRLVPRKGQDMLIRALPAIRQRAPGAALVIVGGGPYRTS
MSMEG_4253|M.smegmatis_MC2_155 GLGDRPVVVCLSRLVPRKGQDMLIRALPELRRRVPDTALAIVGGGPYLET
TH_1111|M.thermoresistible__bu RLGERPVVLCLSRLVPRKGQDMLIRALPMIRRRVGDAVLVIVGGGPYRTA
Mb2211c|M.bovis_AF2122/97 RLGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVGGGPYLET
Rv2188c|M.tuberculosis_H37Rv RLGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVGGGPYLET
MMAR_3232|M.marinum_M QLGERPTVVCVSRLVPRKGQDTLIKALPAIRRRVDGAALVIVGGGPYLET
MUL_3543|M.ulcerans_Agy99 QLGERPTVVCVSRLVPRKGQDTLIKALPAIRRRVDGAALVIVGGGPYLET
MLBr_00886|M.leprae_Br4923 RLGERPTVVCLARLVPRKGQDMLIRALPSIRQRADGAALMIVGGGPYLGT
MAV_2306|M.avium_104 GLGERPTVVCVSRLVPRKGQDMLIRAMPSIVQRVDGAALVIVGGGPHLQS
MAB_1976|M.abscessus_ATCC_1997 GLGDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGGPYAEP
**:**.: *::********* *: *:* : .*. .:.* ******: .
Mvan_3550|M.vanbaalenii_PYR-1 LHRLAHTFGVAEDVVFTDGVPGEELPAHHAMADVFAMPCRTRGSGLDVEG
Mflv_2961|M.gilvum_PYR-GCK LHRLAHDFGVADHVVFTDGVPGEELPAHHAMADVFAMPCRTRGSGLDVEG
MSMEG_4253|M.smegmatis_MC2_155 LQRMASDLGVAEHVVFTRGIPAEELPAHHAMADVFAMPCRTRGAGLDVEG
TH_1111|M.thermoresistible__bu LQRLAHRYDVAAHVVFTGGIPAEELPAHHAMADVFAMPCRTRGAGLDVEG
Mb2211c|M.bovis_AF2122/97 LRKLAHDCGVADHVTFTGGVATDELPAHHALADVFAMPCRTRGAGMDVEG
Rv2188c|M.tuberculosis_H37Rv LRKLAHDCGVADHVTFTGGVATDELPAHHALADVFAMPCRTRGAGMDVEG
MMAR_3232|M.marinum_M LRKLARDCEVDEHVTFTGGVPGEELPTHHAMADVFAMPCRTRGSGMDVEG
MUL_3543|M.ulcerans_Agy99 LRKLARDCEVDEHVTFTSGVPGEELPTHHAMADVFAMPCRTRGSGMDVEG
MLBr_00886|M.leprae_Br4923 LRKLAQGCGVADHVIFAGGVAAVEVPAHYTLADVFAMPCRTRGGGMDVEG
MAV_2306|M.avium_104 LRALARDCGVAAQVTFTGGIPAAELPTHHALADVFAMPCRTRGAGLDVEG
MAB_1976|M.abscessus_ATCC_1997 LRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEG
*: :* * .* *: *:. *:*:*:::.***********.*:****
Mvan_3550|M.vanbaalenii_PYR-1 LGIVYLEASSTGVPVVAGRSGGAPETVVDGETGVVVDGWDVGAIAAAVGD
Mflv_2961|M.gilvum_PYR-GCK LGIVYLEASSTGVPVVAGRSGGAPETVRDGETGLVVDGWDVGAIAASVGE
MSMEG_4253|M.smegmatis_MC2_155 LGIVYLEASACGVPVVAGRSGGAPETVLDGKTGTVVDGTDVDAITTAVGD
TH_1111|M.thermoresistible__bu LGIVYLEASATGVPVVAGRSGGAPETVRHGETGLVVDGRDVREIATAVGD
Mb2211c|M.bovis_AF2122/97 LGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRSVDRVADAVAE
Rv2188c|M.tuberculosis_H37Rv LGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRSVDRVADAVAE
MMAR_3232|M.marinum_M LGIVFLEASASGVPVIAGESGGAPETVQHNKTGLVVDGNSVDKVAGAVIE
MUL_3543|M.ulcerans_Agy99 LGIVFLEASASGVPVIAGESGGAPETVQHNKTGLVVDGNSVDKVAGAVIE
MLBr_00886|M.leprae_Br4923 LGIVFLEASATGVPVIAGKSGGAPEAVQHNKTGLVVDGRSVNMVADAVTE
MAV_2306|M.avium_104 LGIVYLEASASGVPVIAGRSGGAPETVQHNKTGLVVDGRSVTEIADAVTE
MAB_1976|M.abscessus_ATCC_1997 LGIVFLEASACGVPVVAGNSGGAPETVRAGETGVVVDGRSVSAITDAIVQ
****:****: ****:**.******:* .:** **** .* :: :: :
Mvan_3550|M.vanbaalenii_PYR-1 LLADPARAAAMGAAGRQAVLDNWRWSRQAEKLARLL---------
Mflv_2961|M.gilvum_PYR-GCK LLADPARAAAMGAAGRQWAVDNWRWSLQAERLARLL---------
MSMEG_4253|M.smegmatis_MC2_155 LLADPRRAAAMGVAGRHWALDNWQWRTRGARLAELLSGRREARQA
TH_1111|M.thermoresistible__bu LLSDPDRAAAMGAAGRQWVVQQWQWQTQADRLARLLQV-------
Mb2211c|M.bovis_AF2122/97 LLIDRDRAVAMGAAGREWVTAQWRWDTLAAKLADFLRGDDAAR--
Rv2188c|M.tuberculosis_H37Rv LLIDRDRAVAMGAAGREWVTAQWRWDTLAAKLADFLRGDDAAR--
MMAR_3232|M.marinum_M VLADRDRAARMGDAGRQWVTSQWRWDTLAARLAELLRGDDTGR--
MUL_3543|M.ulcerans_Agy99 VLADRDRAARMGDAGRQWVTSQWRWDTLAARLAELLRGDDAGR--
MLBr_00886|M.leprae_Br4923 LLTDRDRAAAMGAAGRHWVTAEWRWDTLAARLADLLCGNDSR---
MAV_2306|M.avium_104 LLSDPDRAAAMGAAGRQWVTSQWRWDTLAARLAGLLGD-------
MAB_1976|M.abscessus_ATCC_1997 ILVDPARAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA-----
:* * **. ** *** . :*:* . ::* ::