For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_1113 (-)

annotation: glycosyl transferase
coordinates: 1175363 - 1176490
length: 375

VRVAIVAESFLPNVNGVTNSVLRVIDHLRRTGHEVLVIAPDTPRGQPPADRIHDGVRVHRVPSRMFPKIT
SLPLGVPRPRMIGVLRGFDPDVVHLASPALLGYGGLHAARHLGVPSVAVFQTDVAGFAESYGMGVASRAA
WAWTRHLHSRADRTLAPSTSAMENLAAHRIPRVHRWGRGVDITGFVPSARDEHLRRTWSPDGRPIVGFVG
RLAPEKHVERLAVLAARDDLQLVIVGDGVDRVKLQTVLPTAVFTGELRGAALAAAYASMDVFVHPGEHET
FCQTVQEAMASGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPAAVTHLIAERRRYGIAARRSVLAR
TWPVVCDELIGHYEAVLGRRSLRAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1113--100% (375)glycosyl transferase
M. smegmatis MC2 155MSMEG_5080-1e-1431.67% (221) glycogen synthase
M. smegmatis MC2 155MSMEG_2935-1e-1428.53% (389) phosphatidylinositol alpha-mannosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0572pimB1e-16574.93% (375) mannosyltransferase PIMB
M. gilvum PYR-GCKMflv_5260-0.082.13% (375) glycosyl transferase, group 1
M. tuberculosis H37RvRv0557pimB1e-16574.93% (375) mannosyltransferase PIMB
M. leprae Br4923MLBr_00452-1e-1326.82% (384) putative glycosyltransferase
M. abscessus ATCC 19977MAB_3931c-1e-15772.70% (370) glycosyl transferase
M. marinum MMMAR_0903pimB1e-16175.75% (367) mannosyltransferase, PimB
M. avium 104MAV_4586-1e-17177.98% (377) glycosyl transferase
M. thermoresistible (build 8)TH_1121-1e-17781.97% (366) MANNOSYLTRANSFERASE PIMB
M. ulcerans Agy99MUL_0656pimB1e-16075.48% (367) mannosyltransferase, PimB
M. vanbaalenii PYR-1Mvan_0978-0.083.73% (375) glycosyl transferase, group 1

CLUSTAL 2.0.9 multiple sequence alignment


Mb0572|M.bovis_AF2122/97            MCGVRVAIVAESFLPQVNGVSNSVVKVLEHLRRTGHEALVIAPDTPPGED
Rv0557|M.tuberculosis_H37Rv         MCGVRVAIVAESFLPQVNGVSNSVVKVLEHLRRTGHEALVIAPDTPPGED
MAV_4586|M.avium_104                ---MRVAIVAESFLPEVNGVSNSVIRVLEHLRRTGHEALVIAPDTPPGQP
MMAR_0903|M.marinum_M               ---MRVAIVAESFLPNVNGVSNSVVRVLEHLRRTGHEALVIAPDNPPGEP
MUL_0656|M.ulcerans_Agy99           ---MRVAIVAESFLPNVNGVSNSVVRVLEHLRRTGHEALVIAPDNPPGEP
Mflv_5260|M.gilvum_PYR-GCK          ---MRVAIVAESFLPNVNGVTNSVLRVIEHLRRTGHEALVIAPDTPRGEP
Mvan_0978|M.vanbaalenii_PYR-1       ---MRVAIVAESFLPNVNGVTNSVLRVIEHLRRTGHEVLVIAPDTPRGQP
MSMEG_1113|M.smegmatis_MC2_155      ---MRVAIVAESFLPNVNGVTNSVLRVIDHLRRTGHEVLVIAPDTPRGQP
TH_1121|M.thermoresistible__bu      ---VRVAIVTESFLPHVNGVTNSVLRVVEHLRGTGHEVLVIAPDTPPGQP
MAB_3931c|M.abscessus_ATCC_199      ---MRIAIVAESFLPNVNGVSNSVLRVLEHFRRTGHEAIVIAPDTPRGQA
MLBr_00452|M.leprae_Br4923          ---MRIGMICPYSFDVPGGVQSHVLQLAEVMRARGQQVRVLAPASPDVSL
                                       :*:.::    :   .** . *::: : :*  *::. *:** .*  . 

Mb0572|M.bovis_AF2122/97            RAERLHDGVRVHRVPSRMFPKVTTLPLG-VPTFRMLRALRGFDPDVVHLA
Rv0557|M.tuberculosis_H37Rv         RAERLHDGVRVHRVPSRMFPKVTTLPLG-VPTFRMLRALRGFDPDVVHLA
MAV_4586|M.avium_104                RAERIHDGIRVHRVPSRMFPKVTTLPLG-VPTPRLVSVLRGFDPHVVHLA
MMAR_0903|M.marinum_M               RADRLHDGVRVHRTPARMFPKVTTLPLG-VPTPRILRVLRGFEPDVVHLA
MUL_0656|M.ulcerans_Agy99           RADRLHDGVRVHRTPARMFPEVTTLPLG-VPTPRILRVLRGFEPDVVHLA
Mflv_5260|M.gilvum_PYR-GCK          PADRVYDGVRVHRVPSAMFPKVTSLPLG-VPRPRMVGVLRGFDPDVVHLA
Mvan_0978|M.vanbaalenii_PYR-1       AADKVYEGVRVHRVPSMMFPKITSLPLG-VPRPRMVGVLRGFDPDVVHLA
MSMEG_1113|M.smegmatis_MC2_155      PADRIHDGVRVHRVPSRMFPKITSLPLG-VPRPRMIGVLRGFDPDVVHLA
TH_1121|M.thermoresistible__bu      PAERVHDGVRIHRVPSRMFPKITSLPLG-IPRPRMIGVLRGFDPDVVHLA
MAB_3931c|M.abscessus_ATCC_199      PAATEYAGVPVHRVPAIMFPKVSTLPLG-VPQPRMVRIFREFAPDVVHLA
MLBr_00452|M.leprae_Br4923          PEYVVSAGR---AIPIPYNGSVARLQFSPAVHSRVRRWLVDGDFDVLHLH
                                           *      *     .:: * :.     *:   :     .*:** 

Mb0572|M.bovis_AF2122/97            SPALLGYGGLHAARRLGVPTVAVYQTDVPGFASSYGIPMTARAAWAWFRH
Rv0557|M.tuberculosis_H37Rv         SPALLGYGGLHAARRLGVPTVAVYQTDVPGFASSYGIPMTARAAWAWFRH
MAV_4586|M.avium_104                SPALLGYGGLRAARWLGVPTVAVYQTDVPGFAASYGIPMTARAAWAWFRH
MMAR_0903|M.marinum_M               SPALLGYGALRAARRLGVPTVAVYQTDVPGFAASYGIAATSRAAWAWFRH
MUL_0656|M.ulcerans_Agy99           SPALLGYGALRAARRLGVPTVAVYQTDVLGFAASYGIAATSRAAWAWFRH
Mflv_5260|M.gilvum_PYR-GCK          SPALLGWGGVHAARHLGVPTVAVFQTDVAGFAQSYGIGMMSRASWAWTRR
Mvan_0978|M.vanbaalenii_PYR-1       SPALLGWGGVHAARRLGIPTVAVFQTDVAGFAESYGIGMLSHASWAWTRR
MSMEG_1113|M.smegmatis_MC2_155      SPALLGYGGLHAARHLGVPSVAVFQTDVAGFAESYGMGVASRAAWAWTRH
TH_1121|M.thermoresistible__bu      SPALLGYGGLLAARRLRVPTVAVFQTDVAGFAASYGMGVAARAAWAWTRH
MAB_3931c|M.abscessus_ATCC_199      SPFVLGYGGLRAAQHLDVPVVAVYQTDVAGFADSYGAGFAARAAWRWTKH
MLBr_00452|M.leprae_Br4923          EPNAPSLS-MWALRVAEGPIVATFHTSTT---KSLTLSVFQGVLRPWHEK
                                    .*   . . : * :    * **.::*..     *        .   * .:

Mb0572|M.bovis_AF2122/97            LHRLADRTLAPSTATMESLIAQGIPR-----VHRWARGVDVQRFAPSARN
Rv0557|M.tuberculosis_H37Rv         LHRLADRTLAPSTATMESLIAQGIPR-----VHRWARGVDVQRFAPSARN
MAV_4586|M.avium_104                LHTLADRTLAPSTVTMESLVAHRFPR-----VHRWARGVDVLRFAPSARS
MMAR_0903|M.marinum_M               LHGLADRTLAPSTPTMQTLLDQGFPR-----VHRWARGVDLIRFAPSARD
MUL_0656|M.ulcerans_Agy99           LHGLADRTLAPSTPTMQTLLDQGFPR-----VHRWARGVDLIRFAPSARD
Mflv_5260|M.gilvum_PYR-GCK          LHSKADRTLAPSTSAMENLAAHGIPR-----VHKWARGVDVTGFAPSARD
Mvan_0978|M.vanbaalenii_PYR-1       LHSKADRTLAPSTSAMENLAAHRIPR-----VHKWARGVDVTGFAPSARD
MSMEG_1113|M.smegmatis_MC2_155      LHSRADRTLAPSTSAMENLAAHRIPR-----VHRWGRGVDITGFVPSARD
TH_1121|M.thermoresistible__bu      LHRLADRTLAPSTAAMRDLARHGVPR-----VHLWARGVDVGGFAPSARD
MAB_3931c|M.abscessus_ATCC_199      LHGRADRTLAPSSSAMEDLAMHGIPR-----VFRWSRGVDIERFAPSARD
MLBr_00452|M.leprae_Br4923          IIGRIAVSDLARRWQMEALGSDAVEIPNGVNVDSLSSAPQLAGYPRLGKT
                                    :      :  .    *. *  . .       *   . . ::  :   .: 

Mb0572|M.bovis_AF2122/97            EVLRRRWSPDGKPIVGFVGRLAPEKHVDRLTGLAASGAVRLVIVGDGID-
Rv0557|M.tuberculosis_H37Rv         EVLRRRWSPDGKPIVGFVGRLAPEKHVDRLTGLAASGAVRLVIVGDGID-
MAV_4586|M.avium_104                EALRRRWSPQGKPIVGFVGRLAPEKHVERLAGLAASDAVQLVVVGDGVD-
MMAR_0903|M.marinum_M               ESLRRRWSPDGRPIVGFVGRLAPEKHAERLAGLAASGAVTLVIVGAGVD-
MUL_0656|M.ulcerans_Agy99           ESLRRRWSPDGRPIVGFVGRLAPEKDAERLAGLAASGAVTLVIVGAGVD-
Mflv_5260|M.gilvum_PYR-GCK          QRLRQSWSPQGKPIVGFVGRLAPEKHVERLAPLHARDDIQLVIVGDGVD-
Mvan_0978|M.vanbaalenii_PYR-1       ERLRRSWSPDGRPIIGFVGRLAPEKHVERLAALHARDDLQIVVVGDGVD-
MSMEG_1113|M.smegmatis_MC2_155      EHLRRTWSPDGRPIVGFVGRLAPEKHVERLAVLAARDDLQLVIVGDGVD-
TH_1121|M.thermoresistible__bu      EQLRRRWSPDGKPIVGFVGRLAPEKHVERLRALAPRTDLQLVIVGDGVD-
MAB_3931c|M.abscessus_ATCC_199      DELRRAWSPKGKPIIGFVGRLAPEKHVERLAVLAGRDDLQLVIVGGGVE-
MLBr_00452|M.leprae_Br4923          VLFLGRYDEPRKGMSVLLDALP--------GVMECFDDVQLLIVGRGDEE
                                      :   :.   : :  ::. *.          :     : :::** * : 

Mb0572|M.bovis_AF2122/97            --RARLQSAMPTAVFTGARYGKELAEAYASMDVFVHSGEH-ETFCQVVQE
Rv0557|M.tuberculosis_H37Rv         --RARLQSAMPTAVFTGARYGKELAEAYASMDVFVHSGEH-ETFCQVVQE
MAV_4586|M.avium_104                --RAKLQSAMPTAVFTGALYGDELAAAYASMDVFVHPGEH-ETFCQVVQE
MMAR_0903|M.marinum_M               --RRKLELAMPTAVFTGALYGDELAAAYASMDVFVHAGEH-ETFCQVVQE
MUL_0656|M.ulcerans_Agy99           --RRKLELAMPTAVFTGALYGDELAAAYASMDVFVHAGEH-ETFCQVVQE
Mflv_5260|M.gilvum_PYR-GCK          --RARLESAFPRAVFTGALYGPELAAAYASMDVFVHGGEH-ETFCQAVQE
Mvan_0978|M.vanbaalenii_PYR-1       --RAKLESELPRAVFTGALYGDELAAAYASMDVFVHPGEH-ETFCQAVQE
MSMEG_1113|M.smegmatis_MC2_155      --RVKLQTVLPTAVFTGELRGAALAAAYASMDVFVHPGEH-ETFCQTVQE
TH_1121|M.thermoresistible__bu      --RRKLENLLPTAVFTGALYGEQLAAAYASMDVFVHPGEH-ETFCQAVQE
MAB_3931c|M.abscessus_ATCC_199      --REALEKLMPTAVFTGELTGSALSRAYASLDVFIHPGEH-ETFCQAVQE
MLBr_00452|M.leprae_Br4923          QLRSQAGGLVEHIRFLGQVDDAGKAAAMRSADVYCAPNIGGESFGIVLVE
                                      *      .    * *   .   : *  * **:   .   *:*  .: *

Mb0572|M.bovis_AF2122/97            ALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPDAVAHLVH--E
Rv0557|M.tuberculosis_H37Rv         ALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPDAVAHLVH--E
MAV_4586|M.avium_104                ALASGLPVIAPDAGGPRDLVTPWRTGLLLAVDEFETKLPAAVAHLIG--E
MMAR_0903|M.marinum_M               ALASGLPVIAPDAGGPRDLVTPQRTGLLLPVDGFETQLPAAVAHLVH--E
MUL_0656|M.ulcerans_Agy99           ALASGLPVIAPDAGGPRDLVAPQRTGLLLPVDGFETQLPAAVAHLVH--E
Mflv_5260|M.gilvum_PYR-GCK          AMASGLPVIAPDAGGPRDLVAPYRSGLLLPVAEFEDRLSESVDHLVV--E
Mvan_0978|M.vanbaalenii_PYR-1       AMASGLPVIAPDAGGPRDLVAPYRTGLLLPVAEFESRLAESVDHLVA--E
MSMEG_1113|M.smegmatis_MC2_155      AMASGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPAAVTHLIA--E
TH_1121|M.thermoresistible__bu      ALASGLPVIAPDAGGPRDLVAPCRTGLLLPVEEFETRLAGAVDHLLA--E
MAB_3931c|M.abscessus_ATCC_199      ALASGVPSIAPDAGGPRDLVIPGRNGMLLPVADFEARLGMAVDHLVQPAT
MLBr_00452|M.leprae_Br4923          AMAAGTPVVASDLDAFRRVLRDGEVGHLVPAGDSAALADALVALLRNDVL
                                    *:*:* * :*.* .. * ::   . * *: .          *  *     

Mb0572|M.bovis_AF2122/97            RQRYALAARRSVLGRSWPVVCDELLGHYEAVRG---RRTTQAA------
Rv0557|M.tuberculosis_H37Rv         RQRYALAARRSVLGRSWPVVCDELLGHYEAVRG---RRTTQAA------
MAV_4586|M.avium_104                RHRYAPAARRSVLGRSWPVICDELLGHYEAVLSPFVRRQVRAGRYAQGE
MMAR_0903|M.marinum_M               RQRYSQAARRSVLGRSWSVICDELLDHYAEVLAPTGRAQDWLWRRRRA-
MUL_0656|M.ulcerans_Agy99           RQRYSQAARRSVLGRSWSVICDELLDHYAEVLAPTGRAQDWLWRRRRA-
Mflv_5260|M.gilvum_PYR-GCK          RRRYSQAARRSVLGRTWPVICDELVGHYEAVVG---ARALRAA------
Mvan_0978|M.vanbaalenii_PYR-1       RRRYSVAARRSVLGRTWPVICDELLGHYEAVMG---ARRLRAA------
MSMEG_1113|M.smegmatis_MC2_155      RRRYGIAARRSVLARTWPVVCDELIGHYEAVLG---RRSLRAA------
TH_1121|M.thermoresistible__bu      RPRYAVAARRSVLGRTWPAICDQLLEHYAAVXX---AVAHPAPHRHAG-
MAB_3931c|M.abscessus_ATCC_199      RSRFSAAARRGVLARTWPAICDELLEHYAAAAGTTLGRGIMTA------
MLBr_00452|M.leprae_Br4923          RERYVAAGAEAVRRYDWSVVASQIMRVYETVATSGSKVQVAS-------
                                    * *:  *. ..*    *..:..:::  *  .