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MSLTAHDGRFCSRYACCSGRQLLWTSLGRTPHRGGPAGRGILRQRTRGVLIVPGARTERHLLRTGVVRIT LPAKHIPYTGGYRAVMPGAVRTVLETLRPDTLEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLL PRRAAQKFADFANARTAANYDTVVCTTGFAREEFDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATP TQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGPLRARLERKATGLPIDFTGFISDRHAVA GLLASADVALAPGPHETFGLAALESLACGTPAVVSRTSALTEIITADSGACADNRPEAIAHAVRTIVSRP ERHRRRCARRRAEIFTWQRAAASMLATLGAMAVSTRCGDTQDTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1785c | - | - | 100% (394) | hypothetical protein Mb1785c |
| M. bovis AF2122 / 97 | Mb0572 | pimB | 4e-15 | 29.50% (322) | mannosyltransferase PIMB |
| M. bovis AF2122 / 97 | Mb3058 | - | 1e-14 | 26.04% (361) | transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3310 | - | 1e-124 | 69.60% (329) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv0557 | pimB | 4e-15 | 29.50% (322) | mannosyltransferase PIMB |
| M. leprae Br4923 | MLBr_01715 | - | 3e-12 | 28.64% (220) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3931c | - | 9e-14 | 26.71% (307) | glycosyl transferase |
| M. marinum M | MMAR_2629 | - | 1e-146 | 78.98% (333) | glycosyl transferase |
| M. avium 104 | MAV_2143 | - | 1e-150 | 78.26% (345) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_1113 | - | 4e-13 | 27.93% (290) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_0088 | - | 1e-12 | 29.21% (202) | glycosyl transferase |
| M. ulcerans Agy99 | MUL_3104 | - | 1e-142 | 79.31% (319) | glycosyl transferase |
| M. vanbaalenii PYR-1 | Mvan_3033 | - | 1e-134 | 72.81% (331) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0557|M.tuberculosis_H37Rv ---------------------MCGVRVAIVAESFLPQ----VNG--VSNS
MSMEG_1113|M.smegmatis_MC2_155 ------------------------MRVAIVAESFLPN----VNG--VTNS
MAB_3931c|M.abscessus_ATCC_199 ------------------------MRIAIVAESFLPN----VNG--VSNS
Mflv_3310|M.gilvum_PYR-GCK ------------------------MRVVQVANFYGPR----SGG--LRTA
Mvan_3033|M.vanbaalenii_PYR-1 ------------------------MRVVQVANFYGPR----SGG--LRTA
MMAR_2629|M.marinum_M ------------------------MRVVQVANFYGPR----SGG--LRTA
MUL_3104|M.ulcerans_Agy99 ------------------------MRVVQVANFYGPR----SGG--LRTA
MAV_2143|M.avium_104 ------------------------MRVVQVANFYGPR----SGG--LRTA
Mb1785c|M.bovis_AF2122/97 ------------------------MSLTAHDGRFCSRYACCSGRQLLWTS
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPV---VIGG--LGRH
TH_0088|M.thermoresistible__bu ------------------------MRIALLSYRSKTH----CGG--QGVY
: : . .
Rv0557|M.tuberculosis_H37Rv VVKVLEHLRRTGHEAL---------VIAPDTPPGEDRAERLHDGVRVHRV
MSMEG_1113|M.smegmatis_MC2_155 VLRVIDHLRRTGHEVL---------VIAPDTPRGQPPADRIHDGVRVHRV
MAB_3931c|M.abscessus_ATCC_199 VLRVLEHFRRTGHEAI---------VIAPDTPRGQAPAATEYAGVPVHRV
Mflv_3310|M.gilvum_PYR-GCK VDRLGAEYCAAGHTVH---------LIVPGRHPET---VTLSSGVERISL
Mvan_3033|M.vanbaalenii_PYR-1 VDRLGAEYCAAGHTVF---------LIVPGPHPER---VTLPSGVVRICL
MMAR_2629|M.marinum_M VDRLGAEYCASGHEVF---------LIVPGAHTGQ---RRLDTGVVRISV
MUL_3104|M.ulcerans_Agy99 VDRLGAEYCASGHEVF---------LIVPGAHTGQ---RRLDTGVVRISL
MAV_2143|M.avium_104 VDRLGAEYCAHGHEVF---------LIVPGQRTER---ARLYTGVVRITL
Mb1785c|M.bovis_AF2122/97 LGRTPHRGGPAGRGILRQRTR--GVLIVPGARTER---HLLRTGVVRITL
MLBr_01715|M.leprae_Br4923 VHHLSTALAAAGHDVVVLSRR--PSGTDPCTHPTS---DEISEGVRVIAA
TH_0088|M.thermoresistible__bu VRHLSRGLVELGHQVEVFSGQPYPEGLDPRVKLTKVPSLDLYREPDPFRI
: : *: *
Rv0557|M.tuberculosis_H37Rv P--------SRMFPKVTT----LPLGVPTFRMLRALRGFDPDVVHLASPA
MSMEG_1113|M.smegmatis_MC2_155 P--------SRMFPKITS----LPLGVPRPRMIGVLRGFDPDVVHLASPA
MAB_3931c|M.abscessus_ATCC_199 P--------AIMFPKVST----LPLGVPQPRMVRIFREFAPDVVHLASPF
Mflv_3310|M.gilvum_PYR-GCK P--------ARLIPCTGG----YRAVLPR-PVTALLGHLRPDALEVSDRL
Mvan_3033|M.vanbaalenii_PYR-1 P--------ARLIPYTGG----YRAVHPG-PVIALLAELRPDALEVSDRL
MMAR_2629|M.marinum_M P--------AKLIPLTGG----YRAVMPG-RVRELLGALDPDAVEVSDRL
MUL_3104|M.ulcerans_Agy99 P--------ANLIPLTGG----YRAVMPG-RVRELLGALDPDAVEVSDRL
MAV_2143|M.avium_104 P--------ARLIPFTGG----YRAVLPG-PVKALLEALRPDALEVSDRL
Mb1785c|M.bovis_AF2122/97 P--------AKHIPYTGG----YRAVMPG-AVRTVLETLRPDTLEVSDRL
MLBr_01715|M.leprae_Br4923 A--------QDPHEFTFSNDMMAWTLAMGHAMIRTGLSLTRHSSDLPWRP
TH_0088|M.thermoresistible__bu PRPSEIRDRIDLLELLTTWTAGFPEPKTFTMRMARILAERRDEFDVVHDN
. . .:
Rv0557|M.tuberculosis_H37Rv LLGYGGLHAARRLGVPTVAVYQTDVPG-FASSYG-IPMTARAAWAWFRHL
MSMEG_1113|M.smegmatis_MC2_155 LLGYGGLHAARHLGVPSVAVFQTDVAG-FAESYG-MGVASRAAWAWTRHL
MAB_3931c|M.abscessus_ATCC_199 VLGYGGLRAAQHLDVPVVAVYQTDVAG-FADSYG-AGFAARAAWRWTKHL
Mflv_3310|M.gilvum_PYR-GCK TLRSLGPWGRRH-GVSTVMISHERLDR-LVGQALPNPLARWVADAANRRT
Mvan_3033|M.vanbaalenii_PYR-1 TLRSLGPWGRRH-GVSTVMISHERLDR-LVGQILPVPIARAVADVANRRT
MMAR_2629|M.marinum_M TLRSLGCWGRER-GITTVMISHERLDR-LVGQVLPHRAAQRLADFANRRT
MUL_3104|M.ulcerans_Agy99 TLRSLGCWGRER-GITTVMISHERLDR-LVGQVLPHRAAQRLADFANRRT
MAV_2143|M.avium_104 TLRSLGRWGRDH-GVTTVMISHERLDR-LVGQVLPRRAAQKFADLANART
Mb1785c|M.bovis_AF2122/97 TLRSLGRWGREH-GVTTVMISHERLDR-FAGQLLPRRAAQKFADFANART
MLBr_01715|M.leprae_Br4923 DVVHAHDWLVAHPAITLAQFYDVPMVS-TIHATEAGRHSGWVSGALSRQV
TH_0088|M.thermoresistible__bu QSLGTGLLELADLGLPVVATVHHPITRDKVVEVAAAKWWRKPLVRRWYGF
:. . . :
Rv0557|M.tuberculosis_H37Rv HRLADRTLAPSTATMESLIAQGIPRVHRWARGVDVQRFAPSARNEV---L
MSMEG_1113|M.smegmatis_MC2_155 HSRADRTLAPSTSAMENLAAHRIPRVHRWGRGVDITGFVPSARDEH---L
MAB_3931c|M.abscessus_ATCC_199 HGRADRTLAPSSSAMEDLAMHGIPRVFRWSRGVDIERFAPSARDDE---L
Mflv_3310|M.gilvum_PYR-GCK AASYDTVVCTTAFARAEFDRIGATNVMTVPLGVDLDQFHPRRRSWA---V
Mvan_3033|M.vanbaalenii_PYR-1 AANYDAVVCTTAFAREEFDRIGATNVATVPLGVDLEQFHPRRRSAE---V
MMAR_2629|M.marinum_M AANYDTVVCTTAFAREEFDRIGATNTLTVPLGVDLQTFHPRRRCPL---V
MUL_3104|M.ulcerans_Agy99 AANYDTVVCTTAFAREEFDRIGATNTLTVPLGVDLQTFHPRRRCPL---V
MAV_2143|M.avium_104 AADYDTVVCTTGFAREEFDRIGAGNTVTVPLGVDLQTFHPRHHSQL---V
Mb1785c|M.bovis_AF2122/97 AANYDTVVCTTGFAREEFDRIGATNTVTVPLGVDLKTFHPRRRCAR---V
MLBr_01715|M.leprae_Br4923 HAVESWLVRESDSLITCSASMCNEIIELFGPGLAEITVIRNGIDPARWPF
TH_0088|M.thermoresistible__bu AEMQKRVARRIPELITVSSSSAADISADFGVSPGQLHVVPLGVDTELFTP
. . .
Rv0557|M.tuberculosis_H37Rv RRRWSPDGKPIVGFVGR-LAPEKHVDR-LTGLAASG----AVRLVIVGDG
MSMEG_1113|M.smegmatis_MC2_155 RRTWSPDGRPIVGFVGR-LAPEKHVER-LAVLAARD----DLQLVIVGDG
MAB_3931c|M.abscessus_ATCC_199 RRAWSPKGKPIIGFVGR-LAPEKHVER-LAVLAGRD----DLQLVIVGGG
Mflv_3310|M.gilvum_PYR-GCK RRQWAGRGQVLLVHCGR-LSVEKHPHRSIDATAALRRRGIDARLVVVGEG
Mvan_3033|M.vanbaalenii_PYR-1 RRRWAAPEQSLLVHCGR-LSVEKQPHRSIEAVAALRDSGIDARLVVVGEG
MMAR_2629|M.marinum_M RQRFATPRQLLLIHCGR-LSVEKHVDRSIGALAALCDAGVDARLVIVGEG
MUL_3104|M.ulcerans_Agy99 RQRFATPRQLLLIHCGR-LSVEKHVDRSIGALAALCDAGVDARFVIVGEG
MAV_2143|M.avium_104 RRRWAAPTQLLLVHCGR-LSVEKRVDRSIDALGELCHAGVDARLVVVGEG
Mb1785c|M.bovis_AF2122/97 RQHWATPTQILLVHCGR-LSVEKHADRSIDALAALCDAGVDARLVIAGEG
MLBr_01715|M.leprae_Br4923 AARRARTGPAELLYVGR-LEYEKGVHDVIAALPRIRRSYPGTTLTIAGEG
TH_0088|M.thermoresistible__bu SEHRVPGRIIAIASADVPLKGISHLLHAVARLRAKRNLDVQLVSKLEPNG
: . * . : : *
Rv0557|M.tuberculosis_H37Rv IDRARLQSAMP------TAVFTGARYG-KELAEAYASMDVFVHSGEHETF
MSMEG_1113|M.smegmatis_MC2_155 VDRVKLQTVLP------TAVFTGELRG-AALAAAYASMDVFVHPGEHETF
MAB_3931c|M.abscessus_ATCC_199 VEREALEKLMP------TAVFTGELTG-SALSRAYASLDVFIHPGEHETF
Mflv_3310|M.gilvum_PYR-GCK PLRGRLERQPARL----PVDFTGHIGCRDTVAEILASADVALAPGPHETF
Mvan_3033|M.vanbaalenii_PYR-1 PLRARLQRQAVRL----PVEFTGYIGCRDTVADILASADVALAPGPHETF
MMAR_2629|M.marinum_M PLRARLQRQAAGL----PVDFTGFVTHRDTVAQLLASADIALAPGPHETF
MUL_3104|M.ulcerans_Agy99 PLRARLQRQAAGL----PVDFTGFVTHRDTVAQLLASADIPLAPGPHETF
MAV_2143|M.avium_104 PLRARLQRQAARL----AVDFTGFISDRTTVAQLLASADVTLAPGPHETF
Mb1785c|M.bovis_AF2122/97 PLRARLERKATGL----PIDFTGFISDRHAVAGLLASADVALAPGPHETF
MLBr_01715|M.leprae_Br4923 TQQDWLVDQARKYKVIKATRFVGHLNHNELLAALQR-ADAAVLPSHYEPF
TH_0088|M.thermoresistible__bu PTEKLIAELGISD-----IVQASSGLSDSELARLLASAEVACIPSLYEGF
. : .. :: : .. :* *
Rv0557|M.tuberculosis_H37Rv CQVVQEALASGLPVIAPDAGGPRDLITPHRTGLLLPVGEFEHRLPDAVAH
MSMEG_1113|M.smegmatis_MC2_155 CQTVQEAMASGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPAAVTH
MAB_3931c|M.abscessus_ATCC_199 CQAVQEALASGVPSIAPDAGGPRDLVIPGRNGMLLPVADFEARLGMAVDH
Mflv_3310|M.gilvum_PYR-GCK GLAALEALASGTPAVVSRTSALAEILTRDSG---ATADNDPDAVAEAVAG
Mvan_3033|M.vanbaalenii_PYR-1 GLAALEALACGTPAVVSRTSALAEILTDDSG---ATADNDPHAIAHAVST
MMAR_2629|M.marinum_M GLAALESLACGTPAVVSRTSALSEIITTDSG---ASADNDPAAIAAAVRT
MUL_3104|M.ulcerans_Agy99 GLAALESLACGTPAVVSRTSALSEIITTDSG---ASADNDPAAIAAAVRT
MAV_2143|M.avium_104 GLAALESLACGTPAVVSRTSALTEIVTPDSG---ASAANDPAAIARAVSA
Mb1785c|M.bovis_AF2122/97 GLAALESLACGTPAVVSRTSALTEIITADSG---ACADNRPEAIAHAVRT
MLBr_01715|M.leprae_Br4923 GLVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTV
TH_0088|M.thermoresistible__bu SLPAVEAMASGTPIVASRAGALPEVLGPDGECARLVPPADVDALTRVLGE
. *: *.* * :.. .. : : .
Rv0557|M.tuberculosis_H37Rv LVH--ERQRYA-LAARRS-VLGRSWPVVCDELLGHYEAVRGR---RTTQA
MSMEG_1113|M.smegmatis_MC2_155 LIA--ERRRYG-IAARRS-VLARTWPVVCDELIGHYEAVLGR---RSLRA
MAB_3931c|M.abscessus_ATCC_199 LVQPATRSRFS-AAARRG-VLARTWPAICDELLEHYAAAAGTTLGRGIMT
Mflv_3310|M.gilvum_PYR-GCK VLTRPEAQRR--DCARRR-AEQFTWPSSAAGMLR-------VMQNR----
Mvan_3033|M.vanbaalenii_PYR-1 VLTRPEHQRR--HSARQR-AEQFTWPRSAAGMLG-------ALGAR----
MMAR_2629|M.marinum_M IVGWPERQRR--SSARRR-AEMFTWQVAAAGMLTALDADAPGCCGGGDAA
MUL_3104|M.ulcerans_Agy99 IVGWPERQRR--SSARRR-AEMFTWQGWPP----------PGC-------
MAV_2143|M.avium_104 IVSRPERQRR--ISARRR-AEDFTWHRAAAGMLASLR--APVFDDPGGDS
Mb1785c|M.bovis_AF2122/97 IVSRPERHRR--RCARRR-AEIFTWQRAAASMLATLG--AMAVSTRCGDT
MLBr_01715|M.leprae_Br4923 LEDPDAAQQRA-LAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQPRL
TH_0088|M.thermoresistible__bu LLDSPHQRSRLGAAGRQRALDVFSWESVAAQTVSIYERAIC---------
: ..*. *
Rv0557|M.tuberculosis_H37Rv A---------
MSMEG_1113|M.smegmatis_MC2_155 A---------
MAB_3931c|M.abscessus_ATCC_199 A---------
Mflv_3310|M.gilvum_PYR-GCK ----------
Mvan_3033|M.vanbaalenii_PYR-1 ----------
MMAR_2629|M.marinum_M SRAC------
MUL_3104|M.ulcerans_Agy99 ----------
MAV_2143|M.avium_104 EQTA------
Mb1785c|M.bovis_AF2122/97 QDTA------
MLBr_01715|M.leprae_Br4923 PIVEHALPDR
TH_0088|M.thermoresistible__bu ----------