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MAPHGRASQTGTVTSVQRPPMTFGAMMRDWRRRRRLSQLDLALAAGVSARHVSFIETGRSAPSRAMVLRL ATVLDVPQREQNRLFVAAGLAPVYGERSLQAPDMAAVRAGVQMVLAAYDPYPCVMVDRGWWILQANPGAS ILLDGVAPHLLDRPNALRIALHPDGLAPRIRNLAQWRTHLVERLRREVDTAGSAELADLLAEIDSYPGGF DDSPDLGSVAVPLELVTEDGRLLRFLSMVTTFGTALDLTAAELSIEAFLPADDETAASLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3014 | - | - | 100% (270) | XRE family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5465 | - | 7e-06 | 27.21% (147) | XRE family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0023 | - | 3e-05 | 38.46% (65) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3292 | - | 1e-107 | 79.10% (244) | XRE family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0023 | - | 3e-05 | 38.46% (65) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2152 | - | 5e-05 | 42.62% (61) | transcriptional regulator |
| M. avium 104 | MAV_0041 | - | 3e-05 | 38.46% (65) | helix-turn-helix domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3525 | - | 1e-100 | 71.43% (252) | transcriptional regulator, XRE family protein |
| M. thermoresistible (build 8) | TH_1958 | - | 1e-103 | 76.11% (247) | transcriptional regulator, XRE family protein |
| M. ulcerans Agy99 | MUL_1737 | - | 3e-05 | 42.62% (61) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3014|M.vanbaalenii_PYR-1 MAPHGRASQTGTVTSVQRPPMTFGAMMRDWRRRRRLSQLDLALAAGVSAR
Mflv_3292|M.gilvum_PYR-GCK --------------------------MRGWRRRRRLSQLELALHAGVSAR
MSMEG_3525|M.smegmatis_MC2_155 -------------MTSTVPGTSIGSLVRQWRQRRRISQLDLAIEADVSPR
TH_1958|M.thermoresistible__bu --VESRPASGHDAEVTRTAAPAFGAMLRDWRRRRRLSQLDLALEAGVSAR
MMAR_2152|M.marinum_M ----------------------MTALLRAVRRQRGLTLEQLAQRAGLTKS
MUL_1737|M.ulcerans_Agy99 ----------------------MTALLRAVRRQRGLTLEQLAQRAGLTKS
Mb0023|M.bovis_AF2122/97 -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSTM
Rv0023|M.tuberculosis_H37Rv -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSTM
MAV_0041|M.avium_104 -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSIM
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Mvan_3014|M.vanbaalenii_PYR-1 HVSFIETGRSAPSRAMVLRLATVLDVPQREQNRLFVAAGLAPVYGERSLQ
Mflv_3292|M.gilvum_PYR-GCK HISFIETGRAKPSRAMVLRLSSVLGVPQRDQNAMLIAAGLAPAYTERSLD
MSMEG_3525|M.smegmatis_MC2_155 HVSFIETGRAQPSRAMVLRLAEALDVPRREQNQLLLAAGLAPVYAERSLD
TH_1958|M.thermoresistible__bu HVSFMETGRAAPSRTMVLRLAEVLEVPPREQNGLLVAAGYAPVYAERDLD
MMAR_2152|M.marinum_M YLSKIERGQSTPSIAVALKVARALDVD-----------------------
MUL_1737|M.ulcerans_Agy99 YLSKIERGQSTPSIAVALKVARALDVD-----------------------
Mb0023|M.bovis_AF2122/97 GLSYLERGARKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAA
Rv0023|M.tuberculosis_H37Rv GLSYLERGARKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAA
MAV_0041|M.avium_104 GLSYLERGARKPHKSTVQKIENGLGLPPGTYSRLLVAADPEAELARLMAA
:* :* * * : . :: * :
Mvan_3014|M.vanbaalenii_PYR-1 APDMAAVRAGVQMVLAA-------YDPYPCVMVDRGWWILQANPGASILL
Mflv_3292|M.gilvum_PYR-GCK APDMAAVRAGVARVLDA-------YEPFPCVVVTRGWWILQTNAGAGVLL
MSMEG_3525|M.smegmatis_MC2_155 DPEMTAVRDGLTRVLDA-------YDPYPCVAVDREWNLLRANAGAGVML
TH_1958|M.thermoresistible__bu DPEMAAVRHGVQRVLDA-------HDPYPCVAVDRGWRVVQTNAGAAVLL
MMAR_2152|M.marinum_M ----------VGRLFSD-------ESAHETITVDRAHDRLGPQSGR----
MUL_1737|M.ulcerans_Agy99 ----------VGRLFSD-------ESAHETITADRAHDRLGPQSGR----
Mb0023|M.bovis_AF2122/97 QPSNPTAVRRAGAVVVDRHSDTDVLEGYAEAQLDAIKSVIDRLPATTSNE
Rv0023|M.tuberculosis_H37Rv QPSNPTAVRRAGAVVVDRHSDTDVLEGYAEAQLDAIKSVIDRLPATTSNE
MAV_0041|M.avium_104 QPVAEMPARRTGPVVVDRHSDTEVLEGYAEAQLDALKSVIDRLPATTSNE
:. . . : ..
Mvan_3014|M.vanbaalenii_PYR-1 DGVAPHLLDRPNALRIALHPDGLAPRIRNLAQWRTHLVERLRREVDTAGS
Mflv_3292|M.gilvum_PYR-GCK DGVAAHLLERPNALRIALHPDGLAPRIGNLAQWRTHLIERLRREVAVDGC
MSMEG_3525|M.smegmatis_MC2_155 DGVAPHLLERPNALRITLHPEGMAPRIRNLAEWRHHLISRLRREVAVSGS
TH_1958|M.thermoresistible__bu DGVADHLLEQPNALRIALHPDGLAPRIRNLAQWRHHLISRLRREVALSRA
MMAR_2152|M.marinum_M ----YHVLAS-TQLGKTMSPFVVRPTAGQDCASDGPHPEHTGQEFVFVHT
MUL_1737|M.ulcerans_Agy99 ----YHVLAS-TQLGKTMSPFVVRPTAGQDCASDGPHPEHTGQEFVFVHT
Mb0023|M.bovis_AF2122/97 YETYILSVIAQCVKAEMLAASSWRVAVNAGADSTGRLMEHLR-ALEATRG
Rv0023|M.tuberculosis_H37Rv YETYILSVIAQCVKAEMLAASSWRVAVNAGADSTGRLMEHLR-ALEATRG
MAV_0041|M.avium_104 YETYILSVIAQCVKAELLAASSWRVAVNAGADSTGRLMEHLQ-ALEATRV
: : . . .: .
Mvan_3014|M.vanbaalenii_PYR-1 AELADLLAEIDSYPGGFDDSPDLGSVAVPLELVTEDGRLLRFLSMVTTFG
Mflv_3292|M.gilvum_PYR-GCK AELDRLLAEIESYPGGFEHSPDLGGVAVPLVLRTTGGRTLRFLSTVTTFG
MSMEG_3525|M.smegmatis_MC2_155 GGLAALLAEIESYPGGFATKHDLGGVAVPLELDTGRGEVLTFLSTVTTFG
TH_1958|M.thermoresistible__bu PGAVALLAEIESYPGGFDDPGDLGGVVVPLELYTTSRRLLSFLSTVTTFG
MMAR_2152|M.marinum_M G-------SVELDYG--DQTITLG-----------TGDSAYFDASVGHKL
MUL_1737|M.ulcerans_Agy99 G-------SVELDYG--DQTITLG-----------TGDSAYFDASVGHKL
Mb0023|M.bovis_AF2122/97 ALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDIRNRGVIPA
Rv0023|M.tuberculosis_H37Rv ALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDIRNRGVIPA
MAV_0041|M.avium_104 ALLKRMPTSLSARFDRACAQSSLPETIIAALVGVDVDEMWDIRNRGVISP
.:. . * :
Mvan_3014|M.vanbaalenii_PYR-1 TALDLTAAELSIEAFLPADDETAASLR-----------------------
Mflv_3292|M.gilvum_PYR-GCK TALDLTAAELSVEAFLPADDATAAALR-----------------------
MSMEG_3525|M.smegmatis_MC2_155 TALDLTAAELSVEAFLPADEQTAAALRG----------------------
TH_1958|M.thermoresistible__bu TALDLTAAELSIEAFLPADERTASALAGPTSPAAASFPDPDTGTAAARQP
MMAR_2152|M.marinum_M RAVGTERAEVVVVAGAELGGR-----------------------------
MUL_1737|M.ulcerans_Agy99 RAVGTERAEVVVVAGAELGGR-----------------------------
Mb0023|M.bovis_AF2122/97 GALPRVRAFVDAIEAS--HDADEGQQ------------------------
Rv0023|M.tuberculosis_H37Rv GALPRVRAFVDAIEAS--HDADEGQQ------------------------
MAV_0041|M.avium_104 SALPRVRAFTDAVESASRDEASQGDDEEGS--------------------
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