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VSRESAGAAIRALRESRDWSLADLAAATGVSIMGLSYLERGARKPHKSTVQKIENGLGLPPGTYSRLLVA ADPEAELARLMAAQPVAEMPARRTGPVVVDRHSDTEVLEGYAEAQLDALKSVIDRLPATTSNEYETYILS VIAQCVKAELLAASSWRVAVNAGADSTGRLMEHLQALEATRVALLKRMPTSLSARFDRACAQSSLPETII AALVGVDVDEMWDIRNRGVISPSALPRVRAFTDAVESASRDEASQGDDEEGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0041 | - | - | 100% (262) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0023 | - | 1e-120 | 86.33% (256) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0023 | - | 1e-120 | 86.33% (256) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4084c | - | 5e-05 | 33.07% (127) | transcriptional regulator |
| M. marinum M | MMAR_0042 | - | 1e-118 | 81.23% (261) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0052 | - | 4e-08 | 25.51% (247) | hypothetical protein MSMEG_0052 |
| M. thermoresistible (build 8) | TH_1958 | - | 1e-05 | 36.08% (97) | transcriptional regulator, XRE family protein |
| M. ulcerans Agy99 | MUL_0041 | - | 1e-117 | 80.08% (261) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3014 | - | 4e-05 | 38.46% (65) | XRE family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0023|M.bovis_AF2122/97 -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSTM
Rv0023|M.tuberculosis_H37Rv -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSTM
MAV_0041|M.avium_104 -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSIM
MMAR_0042|M.marinum_M -----------------MSRESAGAAIRALRESHDWSLADLAAATGVSIM
MUL_0041|M.ulcerans_Agy99 -----------------MSRESAGAAIRALRESHDWSLADLAAATGVSIM
TH_1958|M.thermoresistible__bu VESRPASGHDAEVTRTAAP--AFGAMLRDWRRRRRLSQLDLALEAGVSAR
Mvan_3014|M.vanbaalenii_PYR-1 MAPHGRASQTGTVTSVQRPPMTFGAMMRDWRRRRRLSQLDLALAAGVSAR
MSMEG_0052|M.smegmatis_MC2_155 ---MTDAEFDLATGEFDVGLVRAGAAAAARRRELDISQRSLAADGIINAG
MAB_4084c|M.abscessus_ATCC_199 -----MPQESDLATAVSNAASDIGGFIRAQREAAQVSVRQLAEKAGVSNP
*. *. * .** :.
Mb0023|M.bovis_AF2122/97 GLSYLERGARKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAA
Rv0023|M.tuberculosis_H37Rv GLSYLERGARKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAA
MAV_0041|M.avium_104 GLSYLERGARKPHKSTVQKIENGLGLPPGTYSRLLVAADPEAELARLMAA
MMAR_0042|M.marinum_M GLSYLERGARKPHKGTVQKVENGLGLPPGTYSRLLVAADPEAELARLLAA
MUL_0041|M.ulcerans_Agy99 GLSYLERGARKPHKGTVQKVENGLGLPPGTYSRMLVAADPEAELARLLAA
TH_1958|M.thermoresistible__bu HVSFMETGRAAPSRTMVLRLAEVLEVPPREQNGLLVAAGYAPVYAERDLD
Mvan_3014|M.vanbaalenii_PYR-1 HVSFIETGRSAPSRAMVLRLATVLDVPQREQNRLFVAAGLAPVYGERSLQ
MSMEG_0052|M.smegmatis_MC2_155 ALIAFEKGRSWPRERTRLKLEEVLRWPPGTIARLRQGGSVPTTSAPVAPP
MAB_4084c|M.abscessus_ATCC_199 YLSQIERGLRRPSAEVLNQIAKALRVS---AEVLYVRAG--------ILD
: :* * * :: * . : ..
Mb0023|M.bovis_AF2122/97 QPSNPTAVR--RAGAVVVDRHSDTDVLEGYAEAQLDA-IKSVIDRLPATT
Rv0023|M.tuberculosis_H37Rv QPSNPTAVR--RAGAVVVDRHSDTDVLEGYAEAQLDA-IKSVIDRLPATT
MAV_0041|M.avium_104 QPVAEMPAR--RTGPVVVDRHSDTEVLEGYAEAQLDA-LKSVIDRLPATT
MMAR_0042|M.marinum_M RPTETASPR--RPGVVVVDRHSDTDVLEGYAEAQLDA-LRSVIDRLPAST
MUL_0041|M.ulcerans_Agy99 RPTETASPR--RRGVVVVDRHSDTDVLEGYAEAQLDA-LRSVIDRLPAST
TH_1958|M.thermoresistible__bu DPEMAAVRHGVQRVLDAHDPYPCVAVDRGWRVVQTNAGAAVLLDGVADHL
Mvan_3014|M.vanbaalenii_PYR-1 APDMAAVRAGVQMVLAAYDPYPCVMVDRGWWILQANPGASILLDGVAPHL
MSMEG_0052|M.smegmatis_MC2_155 PPPEPPAAA---PAPVTSVPAADEVPLIAQAVLTAVHTLETTINAMPPES
MAB_4084c|M.abscessus_ATCC_199 RSDASPVRD------------------------------AIIADTFITER
. : .
Mb0023|M.bovis_AF2122/97 SNEYETYILSVIAQCVKAEMLAASSWRVAVNAGADSTGRLMEHLRALEAT
Rv0023|M.tuberculosis_H37Rv SNEYETYILSVIAQCVKAEMLAASSWRVAVNAGADSTGRLMEHLRALEAT
MAV_0041|M.avium_104 SNEYETYILSVIAQCVKAELLAASSWRVAVNAGADSTGRLMEHLQALEAT
MMAR_0042|M.marinum_M SNEYETYILSVVAQCVKAEMLAASSWRVAVNAGSESSARLMEHLQALEAT
MUL_0041|M.ulcerans_Agy99 SNEYDTYILSVVAQCVKAEMLAASSWRVAVNAGSESSARLMEHLQALEAT
TH_1958|M.thermoresistible__bu LEQPNALRIALHPDGLAPRIRNLAQWRHHLISRLRR--EVALSRAPGAVA
Mvan_3014|M.vanbaalenii_PYR-1 LDRPNALRIALHPDGLAPRIRNLAQWRTHLVERLRR--EVDTAGSAELAD
MSMEG_0052|M.smegmatis_MC2_155 DPDFVPRVTAILGDLRQLEAVASRAARISMVT-PPLIKALSAVRRQIDEL
MAB_4084c|M.abscessus_ATCC_199 QKQ---VLLDVYSSFVQQNAEAQS--------------------------
: . .
Mb0023|M.bovis_AF2122/97 RGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDIRNRGVI
Rv0023|M.tuberculosis_H37Rv RGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDIRNRGVI
MAV_0041|M.avium_104 RVALLKRMPTSLSARFDRACAQSSLPETIIAALVGVDVDEMWDIRNRGVI
MMAR_0042|M.marinum_M RTALLERMPASLSARFDRACAQSQLPDAVIAALIGVDSDELWDIRNRGVI
MUL_0041|M.ulcerans_Agy99 RTALLERMPASLSARFDRACALSQLPDAVIAALIGVDSDELWDIRNRGVI
TH_1958|M.thermoresistible__bu LLAEIESYPGGFDDPGDLGGVVVPLELYTTSRRLLSFLSTVTTFGTALDL
Mvan_3014|M.vanbaalenii_PYR-1 LLAEIDSYPGGFDDSPDLGSVAVPLELVTEDGRLLRFLSMVTTFGTALDL
MSMEG_0052|M.smegmatis_MC2_155 TMRAANAPGATLGQRLYAARRQANLTVAETAQAAGVSEDAIARTEAEYPV
MAB_4084c|M.abscessus_ATCC_199 ----------------DVAESDLELPATTE--------------------
. *
Mb0023|M.bovis_AF2122/97 PAGALPRVRAFVDAIEAS--HDADEGQQ------------------
Rv0023|M.tuberculosis_H37Rv PAGALPRVRAFVDAIEAS--HDADEGQQ------------------
MAV_0041|M.avium_104 SPSALPRVRAFTDAVESASRDEASQGDDEEGS--------------
MMAR_0042|M.marinum_M PPGALPRIRAFVDGSTESSQQQDPGCDDGEGQR-------------
MUL_0041|M.ulcerans_Agy99 PPGALPRIRAFVDGSTESSEQQGPGYDDGEGQR-------------
TH_1958|M.thermoresistible__bu TAAELS-IEAFLPADERTASALAGPTSPAAASFPDPDTGTAAARQP
Mvan_3014|M.vanbaalenii_PYR-1 TAAELS-IEAFLPADDETAASLR-----------------------
MSMEG_0052|M.smegmatis_MC2_155 DAAAVHAIEALIDSLR------------------------------
MAB_4084c|M.abscessus_ATCC_199 ----------------------------------------------