For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1958 (-)

annotation: transcriptional regulator, XRE family protein
coordinates: 3802634 - 3803509
length: 292

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1958--100% (292)transcriptional regulator, XRE family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0023-6e-0631.01% (129) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3292-7e-9974.49% (243) XRE family transcriptional regulator
M. tuberculosis H37RvRv0023-6e-0631.01% (129) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4641-3e-0527.34% (128) putative DNA-binding protein
M. marinum MMMAR_3947-3e-0632.54% (126) transcriptional regulatory protein
M. avium 104MAV_0041-2e-0536.08% (97) helix-turn-helix domain-containing protein
M. smegmatis MC2 155MSMEG_3525-1e-10575.20% (250) transcriptional regulator, XRE family protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3014-1e-10376.11% (247) XRE family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_1958|M.thermoresistible__bu      ------VESRPASGHDAEVTRTAAPAFGAMLRDWRRRRRLSQLDLALEAG
MSMEG_3525|M.smegmatis_MC2_155      -----------------MTSTVPGTSIGSLVRQWRQRRRISQLDLAIEAD
Mflv_3292|M.gilvum_PYR-GCK          ------------------------------MRGWRRRRRLSQLELALHAG
Mvan_3014|M.vanbaalenii_PYR-1       ----MAPHGRASQTGTVTSVQRPPMTFGAMMRDWRRRRRLSQLDLALAAG
Mb0023|M.bovis_AF2122/97            ---------------------MSRESAGAAIRALRESRDWSLADLAAATG
Rv0023|M.tuberculosis_H37Rv         ---------------------MSRESAGAAIRALRESRDWSLADLAAATG
MAV_0041|M.avium_104                ---------------------MSRESAGAAIRALRESRDWSLADLAAATG
MMAR_3947|M.marinum_M               -----------------------MPNRGGFVHAARERAGLTCRELAEKAG
MAB_4641|M.abscessus_ATCC_1997      MAGTDERRRELGAFLRVRREHLVRADYGLPPVGRSRTTGLRREEIAYLSG
                                                                       .       ::*  :.

TH_1958|M.thermoresistible__bu      VSARHVSFMETGR-AAPSRTMVLRLAEVLEVPPREQNGLLVAAGYAPVYA
MSMEG_3525|M.smegmatis_MC2_155      VSPRHVSFIETGR-AQPSRAMVLRLAEALDVPRREQNQLLLAAGLAPVYA
Mflv_3292|M.gilvum_PYR-GCK          VSARHISFIETGR-AKPSRAMVLRLSSVLGVPQRDQNAMLIAAGLAPAYT
Mvan_3014|M.vanbaalenii_PYR-1       VSARHVSFIETGR-SAPSRAMVLRLATVLDVPQREQNRLFVAAGLAPVYG
Mb0023|M.bovis_AF2122/97            VSTMGLSYLERGA-RKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELA
Rv0023|M.tuberculosis_H37Rv         VSTMGLSYLERGA-RKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELA
MAV_0041|M.avium_104                VSIMGLSYLERGA-RKPHKSTVQKIENGLGLPPGTYSRLLVAADPEAELA
MMAR_3947|M.marinum_M               CSLRYVHDIEQG--CSPSIRVLNGLVRALQLSAWEQRFLFAACG------
MAB_4641|M.abscessus_ATCC_1997      VSVTWYTWLEQGRDINPSRQVLEAIALEMRLSAAERTYLLELAGFAP-LP
                                     *      :* *    *    :  :   : :.      ::  ..      

TH_1958|M.thermoresistible__bu      ERDLDDP-EMAAVRHGVQRVLDAHDPYPCVAVDRGWRVVQTNAGAAVLLD
MSMEG_3525|M.smegmatis_MC2_155      ERSLDDP-EMTAVRDGLTRVLDAYDPYPCVAVDREWNLLRANAGAGVMLD
Mflv_3292|M.gilvum_PYR-GCK          ERSLDAP-DMAAVRAGVARVLDAYEPFPCVVVTRGWWILQTNAGAGVLLD
Mvan_3014|M.vanbaalenii_PYR-1       ERSLQAP-DMAAVRAGVQMVLAAYDPYPCVMVDRGWWILQANPGASILLD
Mb0023|M.bovis_AF2122/97            RLIAAQPSNPTAVRRAGAVVVDRHS---DTDVLEGYAEAQLDA-IKSVID
Rv0023|M.tuberculosis_H37Rv         RLIAAQPSNPTAVRRAGAVVVDRHS---DTDVLEGYAEAQLDA-IKSVID
MAV_0041|M.avium_104                RLMAAQPVAEMPARRTGPVVVDRHS---DTEVLEGYAEAQLDA-LKSVID
MMAR_3947|M.marinum_M               -RILPDP--ALTDTDISQRYLDALQPHPAAALHPSWRFKAWNQQWQRLFQ
MAB_4641|M.abscessus_ATCC_1997      HSATPDP---APVPDHLLRLVENLVPSPAFVVSADWSIGGWNRAYELLYP
                                          *    .        :          :   :     :     :  

TH_1958|M.thermoresistible__bu      GVADHLLEQPNALRIALHPDGLAPRIRNLAQWRHHLIS------RLRREV
MSMEG_3525|M.smegmatis_MC2_155      GVAPHLLERPNALRITLHPEGMAPRIRNLAEWRHHLIS------RLRREV
Mflv_3292|M.gilvum_PYR-GCK          GVAAHLLERPNALRIALHPDGLAPRIGNLAQWRTHLIE------RLRREV
Mvan_3014|M.vanbaalenii_PYR-1       GVAPHLLDRPNALRIALHPDGLAPRIRNLAQWRTHLVE------RLRREV
Mb0023|M.bovis_AF2122/97            RLPATTSNEYETYILSVIAQCVKAEMLAASSWRVAVNAGADSTGRLMEHL
Rv0023|M.tuberculosis_H37Rv         RLPATTSNEYETYILSVIAQCVKAEMLAASSWRVAVNAGADSTGRLMEHL
MAV_0041|M.avium_104                RLPATTSNEYETYILSVIAQCVKAELLAASSWRVAVNAGADSTGRLMEHL
MMAR_3947|M.marinum_M               GVLLAPS-MHQWLYLSTTSRRILRNWDEVSQWCVGWLR-------YGLAV
MAB_4641|M.abscessus_ATCC_1997      GIASIVPADRNLLRFIFTDPYVRQMLPDWPITSRRFLA-----EYRAEAG
                                     :        :   :      :       .                    

TH_1958|M.thermoresistible__bu      ALSRAPGAVALLAEIESYPGGFD---DPGDLGGVVVPLELYTTSRRLLSF
MSMEG_3525|M.smegmatis_MC2_155      AVSGSGGLAALLAEIESYPGGFA---TKHDLGGVAVPLELDTGRGEVLTF
Mflv_3292|M.gilvum_PYR-GCK          AVDGCAELDRLLAEIESYPGGFE---HSPDLGGVAVPLVLRTTGGRTLRF
Mvan_3014|M.vanbaalenii_PYR-1       DTAGSAELADLLAEIDSYPGGFD---DSPDLGSVAVPLELVTEDGRLLRF
Mb0023|M.bovis_AF2122/97            RALEATRGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDI
Rv0023|M.tuberculosis_H37Rv         RALEATRGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDI
MAV_0041|M.avium_104                QALEATRVALLKRMPTSLSARFDRACAQSSLPETIIAALVGVDVDEMWDI
MMAR_3947|M.marinum_M               DVDAVKPMVSALMPVTEFR---------REWEAQVIPVDPAT---RLWVV
MAB_4641|M.abscessus_ATCC_1997      ALLGDPRHRALVDRLQQQSPEFARAWAEHEVGRFTSRERRFHHPEAGELI
                                                    .            .                   .

TH_1958|M.thermoresistible__bu      LSTVTTFGTALDLTAAELSIEAFLPADERTASALAGPTSPAAASFPDPDT
MSMEG_3525|M.smegmatis_MC2_155      LSTVTTFGTALDLTAAELSVEAFLPADEQTAAALRG--------------
Mflv_3292|M.gilvum_PYR-GCK          LSTVTTFGTALDLTAAELSVEAFLPADDATAAALR---------------
Mvan_3014|M.vanbaalenii_PYR-1       LSMVTTFGTALDLTAAELSIEAFLPADDETAASLR---------------
Mb0023|M.bovis_AF2122/97            RNRGVIPAGALPRVRAFVDAIEAS--HDADEGQQ----------------
Rv0023|M.tuberculosis_H37Rv         RNRGVIPAGALPRVRAFVDAIEAS--HDADEGQQ----------------
MAV_0041|M.avium_104                RNRGVISPSALPRVRAFTDAVESASRDEASQGDDEEGS------------
MMAR_3947|M.marinum_M               RDGGTELRIDMRFWHASPMPGGLLLGVILDAG------------------
MAB_4641|M.abscessus_ATCC_1997      FEHHRLSPSDLPDLHIVIYLPLDGTNTRTKLEALLSGGR-----------
                                     .        :                                       

TH_1958|M.thermoresistible__bu      GTAAARQP
MSMEG_3525|M.smegmatis_MC2_155      --------
Mflv_3292|M.gilvum_PYR-GCK          --------
Mvan_3014|M.vanbaalenii_PYR-1       --------
Mb0023|M.bovis_AF2122/97            --------
Rv0023|M.tuberculosis_H37Rv         --------
MAV_0041|M.avium_104                --------
MMAR_3947|M.marinum_M               --------
MAB_4641|M.abscessus_ATCC_1997      --------