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VSRESAGAAIRALRESRDWSLADLAAATGVSTMGLSYLERGARKPHKSTVQKVENGLGLPPGTYSRLLVA ADPDAELARLIAAQPSNPTAVRRAGAVVVDRHSDTDVLEGYAEAQLDAIKSVIDRLPATTSNEYETYILS VIAQCVKAEMLAASSWRVAVNAGADSTGRLMEHLRALEATRGALLERMPTSLSARFDRACAQSSLPEAVV AALIGVGADEMWDIRNRGVIPAGALPRVRAFVDAIEASHDADEGQQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0023 | - | - | 100% (256) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv3863 | - | 3e-07 | 23.36% (244) | hypothetical protein Rv3863 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0023 | - | 1e-141 | 100.00% (256) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4084c | - | 7e-06 | 32.80% (125) | transcriptional regulator |
| M. marinum M | MMAR_0042 | - | 1e-118 | 83.92% (255) | transcriptional regulatory protein |
| M. avium 104 | MAV_0041 | - | 1e-120 | 86.33% (256) | helix-turn-helix domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0052 | - | 5e-10 | 22.95% (244) | hypothetical protein MSMEG_0052 |
| M. thermoresistible (build 8) | TH_2085 | - | 1e-07 | 26.34% (224) | HYPOTHETICAL ALANINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_0041 | - | 1e-116 | 80.61% (263) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3014 | - | 3e-05 | 38.46% (65) | XRE family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0023|M.tuberculosis_H37Rv -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSTM
Mb0023|M.bovis_AF2122/97 -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSTM
MAV_0041|M.avium_104 -----------------MSRESAGAAIRALRESRDWSLADLAAATGVSIM
MMAR_0042|M.marinum_M -----------------MSRESAGAAIRALRESHDWSLADLAAATGVSIM
MUL_0041|M.ulcerans_Agy99 -----------------MSRESAGAAIRALRESHDWSLADLAAATGVSIM
MSMEG_0052|M.smegmatis_MC2_155 --MTDAEFDLA-TGEFDVGLVRAGAAAAARRRELDISQRSLAADGIINAG
TH_2085|M.thermoresistible__bu --MTDVDLTASPVSEVDPGLARAGAAAAARRRELNISQRRLAAEGIINAG
MAB_4084c|M.abscessus_ATCC_199 -----MPQESDLATAVSNAASDIGGFIRAQREAAQVSVRQLAEKAGVSNP
Mvan_3014|M.vanbaalenii_PYR-1 MAPHGRASQTGTVTSVQRPPMTFGAMMRDWRRRRRLSQLDLALAAGVSAR
*. *. * ** :.
Rv0023|M.tuberculosis_H37Rv GLSYLERGARKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAA
Mb0023|M.bovis_AF2122/97 GLSYLERGARKPHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAA
MAV_0041|M.avium_104 GLSYLERGARKPHKSTVQKIENGLGLPPGTYSRLLVAADPEAELARLMAA
MMAR_0042|M.marinum_M GLSYLERGARKPHKGTVQKVENGLGLPPGTYSRLLVAADPEAELARLLAA
MUL_0041|M.ulcerans_Agy99 GLSYLERGARKPHKGTVQKVENGLGLPPGTYSRMLVAADPEAELARLLAA
MSMEG_0052|M.smegmatis_MC2_155 ALIAFEKGRSWPRERTRLKLEEVLRWPPGTIARLRQGGSVPTTSAPVAPP
TH_2085|M.thermoresistible__bu ALIAFEKGRSWPRERTRAKLEQVLRWPPGTIARLRAGEDVGPAGGPATGA
MAB_4084c|M.abscessus_ATCC_199 YLSQIERGLRRPSAEVLNQIAKALRVS-AEVLYVRAGILDRSDASPVRDA
Mvan_3014|M.vanbaalenii_PYR-1 HVSFIETGRSAPSRAMVLRLATVLDVPQREQNRLFVAAGLAPVYGERSLQ
: :* * * :: * . : . . .
Rv0023|M.tuberculosis_H37Rv QPSNPTAVRRAGAVVVDR-------HSDTDVLEGYAEAQLDAIKSVIDRL
Mb0023|M.bovis_AF2122/97 QPSNPTAVRRAGAVVVDR-------HSDTDVLEGYAEAQLDAIKSVIDRL
MAV_0041|M.avium_104 QPVAEMPARRTGPVVVDR-------HSDTEVLEGYAEAQLDALKSVIDRL
MMAR_0042|M.marinum_M RPTETASPRRPGVVVVDR-------HSDTDVLEGYAEAQLDALRSVIDRL
MUL_0041|M.ulcerans_Agy99 RPTETASPRRRGVVVVDR-------HSDTDVLEGYAEAQLDALRSVIDRL
MSMEG_0052|M.smegmatis_MC2_155 PPPEPPAAAPAPVTS-VP------AADEVPLIAQAVLTAVHTLETTINAM
TH_2085|M.thermoresistible__bu QEPSATRTDQADYRPNAPGSDHGGSDDEVPLVAQAVLAAVNTLDDASEAL
MAB_4084c|M.abscessus_ATCC_199 IIADTFITERQKQVLLDVY---------SSFVQQNAEAQSDVAESDLE-L
Mvan_3014|M.vanbaalenii_PYR-1 APDMAAVRAGVQMVLAAYDPYPCVMVDRGWWILQANPGASILLDGVAPHL
: :
Rv0023|M.tuberculosis_H37Rv PATTSNEYETYILSVIAQCVK--AEMLAASSWRVAVNAGADSTGRLMEHL
Mb0023|M.bovis_AF2122/97 PATTSNEYETYILSVIAQCVK--AEMLAASSWRVAVNAGADSTGRLMEHL
MAV_0041|M.avium_104 PATTSNEYETYILSVIAQCVK--AELLAASSWRVAVNAGADSTGRLMEHL
MMAR_0042|M.marinum_M PASTSNEYETYILSVVAQCVK--AEMLAASSWRVAVNAGSESSARLMEHL
MUL_0041|M.ulcerans_Agy99 PASTSNEYDTYILSVVAQCVK--AEMLAASSWRVAVNAGSESSARLMEHL
MSMEG_0052|M.smegmatis_MC2_155 PPESDPDFVPRVTAILGDLRQ--LEAVASRAARISM-VTPPLIKALSAVR
TH_2085|M.thermoresistible__bu PDVDHPEFTPRLTKILADLRQ--LEAVAARAARISR-VSPRVIKALSAVR
MAB_4084c|M.abscessus_ATCC_199 PATTE---------------------------------------------
Mvan_3014|M.vanbaalenii_PYR-1 LDRPNALRIALHPDGLAPRIRNLAQWRTHLVERLRREVDTAGSAELADLL
Rv0023|M.tuberculosis_H37Rv RALEATRGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDI
Mb0023|M.bovis_AF2122/97 RALEATRGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGADEMWDI
MAV_0041|M.avium_104 QALEATRVALLKRMPTSLSARFDRACAQSSLPETIIAALVGVDVDEMWDI
MMAR_0042|M.marinum_M QALEATRTALLERMPASLSARFDRACAQSQLPDAVIAALIGVDSDELWDI
MUL_0041|M.ulcerans_Agy99 QALEATRTALLERMPASLSARFDRACALSQLPDAVIAALIGVDSDELWDI
MSMEG_0052|M.smegmatis_MC2_155 RQIDELTMRAANAPGATLGQRLYAARRQANLTVAETAQAAGVSEDAIART
TH_2085|M.thermoresistible__bu RSIDELTLRGARAPQATLGQRLYAARRGANLTIEETAQAAGVPAEVIIAA
MAB_4084c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_3014|M.vanbaalenii_PYR-1 AEIDSYPGGFDDSPDLGSVAVPLELVTEDGRLLRFLSMVTTFG--TALDL
Rv0023|M.tuberculosis_H37Rv RNRGVIPAGALPRVRAFVDAIEAS--HDADEGQQ-----
Mb0023|M.bovis_AF2122/97 RNRGVIPAGALPRVRAFVDAIEAS--HDADEGQQ-----
MAV_0041|M.avium_104 RNRGVISPSALPRVRAFTDAVESASRDEASQGDDEEGS-
MMAR_0042|M.marinum_M RNRGVIPPGALPRIRAFVDGSTESSQQQDPGCDDGEGQR
MUL_0041|M.ulcerans_Agy99 RNRGVIPPGALPRIRAFVDGSTESSEQQGPGYDDGEGQR
MSMEG_0052|M.smegmatis_MC2_155 EAEYPVDAAAVHAIEALIDSLR-----------------
TH_2085|M.thermoresistible__bu EADEPVAATAAGAIETLIAELDQP---------------
MAB_4084c|M.abscessus_ATCC_199 ---------------------------------------
Mvan_3014|M.vanbaalenii_PYR-1 TAAELSIEAFLPADDETAASLR-----------------