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TALLRAVRRQRGLTLEQLAQRAGLTKSYLSKIERGQSTPSIAVALKVARALDVDVGRLFSDESAHETITA DRAHDRLGPQSGRYHVLASTQLGKTMSPFVVRPTAGQDCASDGPHPEHTGQEFVFVHTGSVELDYGDQTI TLGTGDSAYFDASVGHKLRAVGTERAEVVVVAGAELGGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1737 | - | - | 100% (180) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_4542 | - | 4e-06 | 35.00% (60) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0484 | - | 5e-06 | 35.00% (60) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1295 | - | 2e-10 | 25.95% (158) | XRE family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0474 | - | 5e-06 | 35.00% (60) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1049 | - | 2e-38 | 47.46% (177) | putative transcription regulator protein |
| M. marinum M | MMAR_2152 | - | 9e-99 | 99.44% (180) | transcriptional regulator |
| M. avium 104 | MAV_3453 | - | 2e-67 | 75.28% (178) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1151 | - | 6e-13 | 28.30% (159) | DNA-binding protein |
| M. thermoresistible (build 8) | TH_3894 | - | 7e-13 | 29.27% (164) | PUTATIVE putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0450 | - | 2e-50 | 59.20% (174) | XRE family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1737|M.ulcerans_Agy99 --------------------------------------MTALLRAVRRQR
MMAR_2152|M.marinum_M --------------------------------------MTALLRAVRRQR
MAV_3453|M.avium_104 --------------------------------------MTALLRPVRRQR
Mvan_0450|M.vanbaalenii_PYR-1 --------------------------------------MSGLLRAVRQER
MAB_1049|M.abscessus_ATCC_1997 --------------------------------------MASLVRALRRER
Mb0484|M.bovis_AF2122/97 -----------------MSSEEKLAAKVSTKASDVASDIGSFIRSQRETA
Rv0474|M.tuberculosis_H37Rv -----------------MSSEEKLAAKVSTKASDVASDIGSFIRSQRETA
Mflv_1295|M.gilvum_PYR-GCK MANQNDRDDHTPLLRNTSGTARDRDPGAPVEELEIESAIGRNVRLLRQQQ
MSMEG_1151|M.smegmatis_MC2_155 -------------------MGKAKPNDNKALVDAMLGDLGSRIRMLRKER
TH_3894|M.thermoresistible__bu --------------------------------------------------
MUL_1737|M.ulcerans_Agy99 GLTLEQLAQRAGLTKSYLSKIERGQSTPSIAVALKVARALDVDVGRLFSD
MMAR_2152|M.marinum_M GLTLEQLAQRAGLTKSYLSKIERGQSTPSIAVALKVARALDVDVGRLFSD
MAV_3453|M.avium_104 GLTLEALAAQTGLTKSYLSKIERGQSTPSIAVALKVARALDVDVGRLFSD
Mvan_0450|M.vanbaalenii_PYR-1 GMTLDDLAADTGLTKSYLSKVERGQSVPSIAAALKISRALEVDVAQLFSD
MAB_1049|M.abscessus_ATCC_1997 GLTLEELGSRTGLTKSYLSKVEREHSTPSVSVAMRIAGALDVDVSRLFTN
Mb0484|M.bovis_AF2122/97 HVSMRQLAERSGVSNPYLSQVERGLRKPSADVLSQIAKALRVSAEVLYVR
Rv0474|M.tuberculosis_H37Rv HVSMRQLAERSGVSNPYLSQVERGLRKPSADVLSQIAKALRVSAEVLYVR
Mflv_1295|M.gilvum_PYR-GCK GLTVAETAARVGISKAMMSKIENAQTSCSLSTLALLAKGFDVPVTSLFRG
MSMEG_1151|M.smegmatis_MC2_155 QLTTERLAETAGVSAGLISQIERGNGNPSFATLVQLAHGLQMPIGQLLEA
TH_3894|M.thermoresistible__bu -VTLAALATETGLSESTLSRLENGKLRPTLEQLLPLARAHGVPIDDLVQA
:: . *:: :*::*. : :: . : *
MUL_1737|M.ulcerans_Agy99 ESAHETITADRAHD------RLGPQSGRYHVLASTQLGKTMSPFVVRPTA
MMAR_2152|M.marinum_M ESAHETITVDRAHD------RLGPQSGRYHVLASTQLGKTMSPFVVRPTA
MAV_3453|M.avium_104 EAAREKIAVERAG---------GPGGRRYRVLASSMLGKTMSPFVIRPT-
Mvan_0450|M.vanbaalenii_PYR-1 DPEVSTISVDRAAE------R---GADRHHAVAARMLGKEMSPFVVRPG-
MAB_1049|M.abscessus_ATCC_1997 DAYESRVVVDRGAD------EWD--DGKFHALSTEMLGKIMTPFLASPS-
Mb0484|M.bovis_AF2122/97 AG------------------------------------------ILEPS-
Rv0474|M.tuberculosis_H37Rv AG------------------------------------------ILEPS-
Mflv_1295|M.gilvum_PYR-GCK ADVERPAAFVKAGTGAR-IVREGTREGHEYQLLGSLRGEHKRLECLEVTL
MSMEG_1151|M.smegmatis_MC2_155 PESKSVVVRKNERRRLDGHGLANDDGGSYELLTPDLNGALEATWVVTPP-
TH_3894|M.thermoresistible__bu PLTGDPRIHLRPIR----------RFGLTVIPLTRRAGGIQAYKIVYPPA
MUL_1737|M.ulcerans_Agy99 GQDCASDGPHPEHTGQEFVFVHTGSVELDYG--DQTIT--LGTGDSAYFD
MMAR_2152|M.marinum_M GQDCASDGPHPEHTGQEFVFVHTGSVELDYG--DQTIT--LGTGDSAYFD
MAV_3453|M.avium_104 --EQLADDPHPEHAGQEFLFVHAGRVELDYG--DQTFT--LGPGDSAYFD
Mvan_0450|M.vanbaalenii_PYR-1 --RTFTTHPHPTHLGQEFIFVHSGRVELSHD--GRIIA--LEAGDCAYFD
MAB_1049|M.abscessus_ATCC_1997 --TEFAEH-KSSHEGQEFVFVHRGSIELQCGQDDEVVSYELDEGDSAYLD
Mb0484|M.bovis_AF2122/97 ----------ETSQVRDAIITDTAITERQKQ---ILLD----------IY
Rv0474|M.tuberculosis_H37Rv ----------ETSQVRDAIITDTAITERQKQ---ILLD----------IY
Mflv_1295|M.gilvum_PYR-GCK S-EKSQTYPLFQHPGTEFIYMLEGVMDYSHS--RSVYR--LQPGDSLQID
MSMEG_1151|M.smegmatis_MC2_155 --GYDTSATPYHHHGEEFGIVLSGTKDVYLDG----IRHRLHAGDSIRYA
TH_3894|M.thermoresistible__bu DRAMTTPLQTQTHEGYEWFYVLNGRVRFVLGEQELLLN----PGEVAEFD
: .
MUL_1737|M.ulcerans_Agy99 ASVGHKLRAVGTERAEVVVVAG--AELGGR-----
MMAR_2152|M.marinum_M ASVGHKLRAVGTERAEVVVVAG--AELGGR-----
MAV_3453|M.avium_104 ASVSHKVRSVGPEPAEVVAVAH--AEPGSAAFAG-
Mvan_0450|M.vanbaalenii_PYR-1 ASAPHKLRQIGEDAAEVVVVAGNAPRPGAPRRRG-
MAB_1049|M.abscessus_ATCC_1997 ATRTHRIRRTSETPALVVIVAAT------------
Mb0484|M.bovis_AF2122/97 ASFTHQNEATREECPSDPTPTDD------------
Rv0474|M.tuberculosis_H37Rv ASFTHQNEATREECPSDPTPTDD------------
Mflv_1295|M.gilvum_PYR-GCK GEGAHGPVDLVEVPIRFLSVIAFPDSQV-------
MSMEG_1151|M.smegmatis_MC2_155 SNIPHWYVNPSETEECTAIWVSTPPTW--------
TH_3894|M.thermoresistible__bu TRIPHWIGSAGPEPAELLTLFGPEGERAHLLTAGD
*