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MANVADANRELADFLKRARSAVDPARAGLPADGRIRRVPGLRREEVALLAGVSTDYYARLEQGRRITPSA AVLDAIARALDLGDTGRAHLGRLVGASPTRRRSSRPVQRVRPGLYQLLDSLDETPAMILGRRTDVLATNR AARVLFADFDAMPPRERNYARWMFTSEQARNLFADWSVQARTAVENLRLDFGGDPHDPAVIELVDELSAA SAEFRMWWAEHRVFQRTYGTKRLRHPVVGDLSVDYETFTMPGDAEQTLFVYLAEAGSPSRDALNLLLSWS ANSV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5465 | - | - | 100% (285) | XRE family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1062 | - | 9e-37 | 37.78% (270) | XRE family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0930 | - | 6e-33 | 36.97% (238) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5170 | - | 1e-28 | 31.20% (266) | XRE family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4641 | - | 1e-37 | 34.53% (278) | putative DNA-binding protein |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1626 | - | 1e-115 | 72.14% (280) | putative DNA-binding protein |
| M. thermoresistible (build 8) | TH_1958 | - | 4e-06 | 29.56% (159) | transcriptional regulator, XRE family protein |
| M. ulcerans Agy99 | MUL_1737 | - | 8e-05 | 45.28% (53) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5465|M.vanbaalenii_PYR-1 MMANVADANRELADFLKRARSAVDPARAGLPADGRIRRVPGLRREEVALL
MSMEG_1626|M.smegmatis_MC2_155 --MVMSDTNRDLADFLKRARAAVDPARAGLPADSRVRRVPGLRREEVALL
Mflv_5170|M.gilvum_PYR-GCK -MDTRAQRRLALGEFLRARREAIRRADVGLPELPRAR-TGGLRREEVAVT
MAB_4641|M.abscessus_ATCC_1997 -MAGTDERRRELGAFLRVRREHLVRADYGLPPVGRSR-TTGLRREEIAYL
TH_1958|M.thermoresistible__bu -----VESRPASGHDAEVTRTAAPAFGAMLRDWRRRR---RLSQLDLALE
MUL_1737|M.ulcerans_Agy99 -------------------------MTALLRAVRRQR---GLTLEQLAQR
* * * * ::*
Mvan_5465|M.vanbaalenii_PYR-1 AGVSTDYYARLEQGRRITPSAAVLDAIARALDLGDTGRAHLGRLVGASPT
MSMEG_1626|M.smegmatis_MC2_155 AGVSTDYYTRLEQGRRITPSRSVLDAIARALDLDDTGRAHLEHLVGAPPR
Mflv_5170|M.gilvum_PYR-GCK AGVSVTWYTWLEQGRDINPSKQVLDAVADALRLSPAEHEYVLALGGYA--
MAB_4641|M.abscessus_ATCC_1997 SGVSVTWYTWLEQGRDINPSRQVLEAIALEMRLSAAERTYLLELAGFAPL
TH_1958|M.thermoresistible__bu AGVSARHVSFMETGR-AAPSRTMVLRLAEVLEVPPREQNGLLVAAGYAPV
MUL_1737|M.ulcerans_Agy99 AGLTKSYLSKIERGQ-STPSIAVALKVARALDVDVG--------------
:*:: : :* *: ** : :* : :
Mvan_5465|M.vanbaalenii_PYR-1 RRRSSRP---VQRVRPGLYQLLDSLDETPAMILGRRTDVLATNRAARVLF
MSMEG_1626|M.smegmatis_MC2_155 GRKPPTA---AQRVRPGLYQLLESLTGTPAMILGRHSDVLGINRLGAALI
Mflv_5170|M.gilvum_PYR-GCK -VDAAVS---RGPLPPHIQHFLDALEGYPAFAITPDWGIAAWNTTYAALY
MAB_4641|M.abscessus_ATCC_1997 PHSATPD---PAPVPDHLLRLVENLVPSPAFVVSADWSIGGWNRAYELLY
TH_1958|M.thermoresistible__bu YAERDLDDPEMAAVRHGVQRVLDAHDPYPCVAVDRGWRVVQTNAGAAVLL
MUL_1737|M.ulcerans_Agy99 -------------------RLFSDESAHETITADRAHDRLGPQSGRYHVL
:... . : :
Mvan_5465|M.vanbaalenii_PYR-1 ADFDAMPPRERNYARWMFTSEQARNLFADWSVQARTAVENLRLDFGGDPH
MSMEG_1626|M.smegmatis_MC2_155 ADFDRMRPRERSYARWMFLSPDARKLFADWDVQARSVVENLRLELGAHPG
Mflv_5170|M.gilvum_PYR-GCK PNVERVPETDRNLLWLVFTDPYIHELLPNWDTDSRRFLAEFRADAGPRVG
MAB_4641|M.abscessus_ATCC_1997 PGIASIVPADRNLLRFIFTDPYVRQMLPDWPITSRRFLAEYRAEAGALLG
TH_1958|M.thermoresistible__bu DGVADHLLEQPNALRIALHPDGLAPRIRNLAQWRHHLISRLRREVALS-R
MUL_1737|M.ulcerans_Agy99 ASTQLGKTMSPFVVRPTAGQDCASD--------------------GPHPE
. . .
Mvan_5465|M.vanbaalenii_PYR-1 DPAVIELVDELSAASAEFRMWWAEH-RVFQRTYGTKRLRHPVVGDLSVDY
MSMEG_1626|M.smegmatis_MC2_155 DPVTTALVDELSAASTDFGDWWAQH-RVYQRTHGSKHLRHPVVGELTVDY
Mflv_5170|M.gilvum_PYR-GCK EPSYTALVSRLSSESPHFAAAWQAT-SIERFTSRERLFRHPAAGELRLEH
MAB_4641|M.abscessus_ATCC_1997 DPRHRALVDRLQQQSPEFARAWAEH-EVGRFTSRERRFHHPEAGELIFEH
TH_1958|M.thermoresistible__bu APGAVALLAEIESYPGGFDDPGDLGGVVVPLELYTTSRRLLSFLSTVTTF
MUL_1737|M.ulcerans_Agy99 HTGQEFVFVHTGSVELDYGD------QTITLGTGDSAYFDASVGHKLRAV
. :. . :
Mvan_5465|M.vanbaalenii_PYR-1 ETFTMPGDAEQTLFVYLAEAGSPSRDALNLLLSWSANSV-----------
MSMEG_1626|M.smegmatis_MC2_155 ETFTMPGDPDQTMFTYTTEAGTASREAMNLLISWTMSSATQPTESSEPA-
Mflv_5170|M.gilvum_PYR-GCK HQVAPVDVPDIQIVAYLPVPDSVASERLRMLTGQADTAR-----------
MAB_4641|M.abscessus_ATCC_1997 HRLSPSDLPDLHIVIYLPLDGTNTRTKLEALLSGGR--------------
TH_1958|M.thermoresistible__bu GTALDLTAAELSIEAFLPADERTASALAGPTSPAAASFPDPDTGTAAARQ
MUL_1737|M.ulcerans_Agy99 GTER----AEVVVVAGAELGGR----------------------------
.: :
Mvan_5465|M.vanbaalenii_PYR-1 -
MSMEG_1626|M.smegmatis_MC2_155 -
Mflv_5170|M.gilvum_PYR-GCK -
MAB_4641|M.abscessus_ATCC_1997 -
TH_1958|M.thermoresistible__bu P
MUL_1737|M.ulcerans_Agy99 -