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MAPTNDQAARWNRYWDKKSRTYDREIGFFDRHLFGDSRQWVCSQATGDVLEVAVGTGLNLNFYPDDVALT GIDWSEQMLERARRRAAEIGRTATLQQADAHHLPFEDASFDTVVCTFGLCAIPDHAQALTEMARVLRPGG KLVLVDHVQSTAAPVRAVQRLLEVFTVPLAGEHFLRRPLSHIRSATGLEIDRVERFKLGLVERLVAHKPV AP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2948 | - | - | 100% (212) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_0109 | - | 2e-15 | 42.14% (140) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_2287 | - | 1e-10 | 37.96% (108) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1440c | - | 2e-14 | 38.78% (98) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_2133 | - | 6e-14 | 32.03% (153) | methyltransferase type 12 |
| M. tuberculosis H37Rv | Rv1405c | - | 2e-14 | 38.78% (98) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 5e-15 | 36.27% (102) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_4018 | - | 4e-12 | 36.36% (121) | similarity with UbiE/COQ5 methyltransferase |
| M. marinum M | MMAR_3393 | - | 7e-17 | 35.33% (150) | methyltransferase |
| M. avium 104 | MAV_3373 | - | 1e-14 | 39.80% (98) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_0098 | - | 6e-13 | 35.33% (150) | methyltransferase |
| M. thermoresistible (build 8) | TH_1988 | - | 3e-13 | 32.48% (117) | methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_0991 | - | 5e-14 | 29.14% (151) | hypothetical protein MUL_0991 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1440c|M.bovis_AF2122/97 ----------MTIDTPAREDQTLAATHRAMWA-LGDYALMAEE---VMAP
Rv1405c|M.tuberculosis_H37Rv ----------MTIDTPAREDQTLAATHRAMWA-LGDYALMAEE---VMAP
MLBr_00551|M.leprae_Br4923 ----------MNLYTPIHEDQSLAAIHRAMWA-LGDYALMAEE---VMAP
MAV_3373|M.avium_104 ----------MTLDTTT-ADASVAARHRTVWA-LGDYALMAEE---VMAP
Mflv_2133|M.gilvum_PYR-GCK ---------------------MSDVVDNPFFA-RLWTAMSSRE---PESL
TH_1988|M.thermoresistible__bu ---------------------MTSTVDNPFFA-RMWTWLSSHE---PEAM
MUL_0991|M.ulcerans_Agy99 ------------------MTSLAKNIDHPFFA-RIWPFIVAHE---AEPV
Mvan_2948|M.vanbaalenii_PYR-1 ----------------MAPTNDQAARWNRYWD-KKSRTYDREIGFFDRHL
MMAR_3393|M.marinum_M ------MNQQDSPSTCYRAEPVDAQAFTAHFD-RLYTRLARPYD-LAVKL
MSMEG_0098|M.smegmatis_MC2_155 --MDTALRRAMDLLIDPPAEPDFSKGYLDLLG-RGDSTAPKNTGLIQKAW
MAB_4018|M.abscessus_ATCC_1997 MLHHPTLADSLIDPARIDHPPRRDHGYLDVLGPESDEPVSVANRFMQSPL
Mb1440c|M.bovis_AF2122/97 LGPI-----------------LVAAAGIGPGV---------RVLDVAAGS
Rv1405c|M.tuberculosis_H37Rv LGPI-----------------LVAAAGIGPGV---------RVLDVAAGS
MLBr_00551|M.leprae_Br4923 LGPI-----------------LVTATGIRPGM---------QVLDVAAGS
MAV_3373|M.avium_104 LGPT-----------------LVEAAGIGPGV---------RVLDVAAGS
Mflv_2133|M.gilvum_PYR-GCK RRLR-----------------RDNLAGLTG-----------RVLEVGAGT
TH_1988|M.thermoresistible__bu RQRR-----------------EQLLAGLSG-----------RVLEVGAGT
MUL_0991|M.ulcerans_Agy99 RALR-----------------RENLAGLSG-----------RVLEIGAGM
Mvan_2948|M.vanbaalenii_PYR-1 FGDS-----------------RQWVCSQATG----------DVLEVAVGT
MMAR_3393|M.marinum_M LPVW-----------------RHWISAALPHIRGP------RVLEVSFGT
MSMEG_0098|M.smegmatis_MC2_155 ASPLGSKLYDRAQLL-----NRRLVASTRPPVEWLRIPPGGTVLDIGCGP
MAB_4018|M.abscessus_ATCC_1997 LAAIYERAWRPMFTRGFSYGGKSTLKAHTALMDEIAGRGDHKILDVACGP
. :*::. *
Mb1440c|M.bovis_AF2122/97 GNISLPAAKTG-ATVISTDLTPELLQRSQARAAQQGLTLQYQEANAQALP
Rv1405c|M.tuberculosis_H37Rv GNISLPAAKTG-ATVISTDLTPELLQRSQARAAQQGLTLQYQEANAQALP
MLBr_00551|M.leprae_Br4923 GNISLPAAKTG-ATIVSTDLTPELLQRSQARATELGLTLEYREADAQALP
MAV_3373|M.avium_104 GNITLPAAAAG-ASVVSTDLTPELLQRSRDRAAGMGLTIDYREANAQALP
Mflv_2133|M.gilvum_PYR-GCK GTNFEFYPSTV-TEVVAVEPERRLAVLAEQAAAGAAVPVTVSTDTVEQFA
TH_1988|M.thermoresistible__bu GTNFAFYPPGV-TEVVAVEPEQRLVAVVRQAAAEAPVPVTVRAETVENFD
MUL_0991|M.ulcerans_Agy99 GTNFAFYPQTV-TEVVAVEPEPHLALRARAAGEDAPIPVTVTADTAEQFS
Mvan_2948|M.vanbaalenii_PYR-1 GLNLNFYPDD--VALTGIDWSEQMLERARRRAAEIGRTATLQQADAHHLP
MMAR_3393|M.marinum_M GWLLTRYANN--FDTYGVDLNRRMVAMARRNLRRAGVSADLSQANVEALP
MSMEG_0098|M.smegmatis_MC2_155 GNITAQLARAAGLDGLALGVDISEPMLARAVAAEAGRQVGFVRADAQQLP
MAB_4018|M.abscessus_ATCC_1997 GLYTRELAAQLGTAGVCIGLDLSGPMLRRAVRDNSAERVDYIRGSAHSLP
* . . .. :
Mb1440c|M.bovis_AF2122/97 FADDEFDTVISAIGVMFAPDHQAAADELVRVCRPGGTIGVISWTCEGFFG
Rv1405c|M.tuberculosis_H37Rv FADDEFDTVISAIGVMFAPDHQAAADELVRVCRPGGTIGVISWTCEGFFG
MLBr_00551|M.leprae_Br4923 FGDGEFDVVMSAIGVMFAPDHRRAASELVRVCRPNGTIGVISWTQEGFFG
MAV_3373|M.avium_104 FGDGEFDAVVSAIGVQFAPDHQRAADELVRVCRPGGRIGLISWTPEGFFG
Mflv_2133|M.gilvum_PYR-GCK DAK-PFDAVVCSLVLCSVDDPEQVVSQLFSVLKPGGELRYLEHVASDGAA
TH_1988|M.thermoresistible__bu SSE-PFDAVVCTLVLCSVDDPAGVVRQLFSLLRPGGELRYLEHIASAG-A
MUL_0991|M.ulcerans_Agy99 DQD-PFDAVVCSLVLCSVTDQLGVLQHLRSLLRPGGELRYLEHIASAG-A
Mvan_2948|M.vanbaalenii_PYR-1 FEDASFDTVVCTFGLCAIPDHAQALTEMARVLRPGGKLVLVDHVQSTAAP
MMAR_3393|M.marinum_M YPDGQFDTVVNTMSFSGYPNGARAMTQLHRVLRRQGRLVLIDVGYPQDGN
MSMEG_0098|M.smegmatis_MC2_155 FRDEVFDAATSLAVFQLIPDPVAAVSEIVRVLKPGGRVAIMVPTAGAVKP
MAB_4018|M.abscessus_ATCC_1997 FADATFDTVVCLAALYLIPDPEQAVRELCRVAGPDGQIVVFTSLRTRAAS
. **.. . : . .: : * : .
Mb1440c|M.bovis_AF2122/97 RMLATIRPYRPSVSADLPPSALWGREAYVTGLLGDGVTGLKTARGLLEVK
Rv1405c|M.tuberculosis_H37Rv RMLATIRPYRPSVSADLPPSALWGREAYVTGLLGDGVTGLKTARGLLEVK
MLBr_00551|M.leprae_Br4923 RMLATIRPYRPSLSAALPPAALWGREAYIRGLLDDTVTNVKTERRQLEVK
MAV_3373|M.avium_104 RMLATIRPYRPSLSHPVPPAALWGRPGYVRALLGERIGEITTARGMLPVN
Mflv_2133|M.gilvum_PYR-GCK RGRLQR----------------FADATFWPRLLGNCHTHRRTED-TITRA
TH_1988|M.thermoresistible__bu RGRLQR----------------FADX----R-------------------
MUL_0991|M.ulcerans_Agy99 RGRLQQ----------------FVDATFWPRIAGNCHTHRDTER-VIKAA
Mvan_2948|M.vanbaalenii_PYR-1 VRAVQR-----------------LLEVFTVPLAGEHFLRRPLSHIRSATG
MMAR_3393|M.marinum_M RLGTALAG--------------------MWQRAGDVIRDMPTLLDDFGFE
MSMEG_0098|M.smegmatis_MC2_155 VTFLARG-------------------------GARIFGDDELGDIFENVG
MAB_4018|M.abscessus_ATCC_1997 LPGVTT---------------------AMRIGGFRAFGRDEVTGWLRAQG
Mb1440c|M.bovis_AF2122/97 RFDTAQAVHDYFKNNYGPTIEAYAHIGDNAVLAAELDRQLVELAAQYLSD
Rv1405c|M.tuberculosis_H37Rv RFDTAQAVHDYFKNNYGPTIEAYAHIGDNAVLAAELDRQLVELAAQYLSD
MLBr_00551|M.leprae_Br4923 RFNSAEGVHNYFKNHYGPTIEAYTNIGDNSVLAAELDAQLTELAQKYLTN
MAV_3373|M.avium_104 RFGSAEDVHAYFKQHYGPTIEAYANIGHNRVLAAELDAQLVELAAQHLSD
Mflv_2133|M.gilvum_PYR-GCK GFRVDDARREWTFPAWVPVPVAEFAIGVARRP------------------
TH_1988|M.thermoresistible__bu --------------------------------------------------
MUL_0991|M.ulcerans_Agy99 GFDVESTRREWTLPTWAPVPVAELVLGRARRP------------------
Mvan_2948|M.vanbaalenii_PYR-1 ---LEIDRVERFKLGLVERLVAHKPVAP----------------------
MMAR_3393|M.marinum_M VQHEQIGGFGSVHLYLATKL------------------------------
MSMEG_0098|M.smegmatis_MC2_155 LVGVRVKTHGFIQWVRGTKL------------------------------
MAB_4018|M.abscessus_ATCC_1997 WTDIDQTVTGQGQFIRARRAVALRVAT-----------------------
Mb1440c|M.bovis_AF2122/97 GVMEWEYLLLTAEKR--
Rv1405c|M.tuberculosis_H37Rv GVMEWEYLLLTAEKR--
MLBr_00551|M.leprae_Br4923 STMGWEYLLLTAQKH--
MAV_3373|M.avium_104 GTMGWEYLLVTAEKRSG
Mflv_2133|M.gilvum_PYR-GCK -----------------
TH_1988|M.thermoresistible__bu -----------------
MUL_0991|M.ulcerans_Agy99 -----------------
Mvan_2948|M.vanbaalenii_PYR-1 -----------------
MMAR_3393|M.marinum_M -----------------
MSMEG_0098|M.smegmatis_MC2_155 -----------------
MAB_4018|M.abscessus_ATCC_1997 -----------------