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M. gilvum PYR-GCK Mflv_2133 (-)

annotation: methyltransferase type 12
coordinates: 2211072 - 2211704
length: 210

MSDVVDNPFFARLWTAMSSREPESLRRLRRDNLAGLTGRVLEVGAGTGTNFEFYPSTVTEVVAVEPERRL
AVLAEQAAAGAAVPVTVSTDTVEQFADAKPFDAVVCSLVLCSVDDPEQVVSQLFSVLKPGGELRYLEHVA
SDGAARGRLQRFADATFWPRLLGNCHTHRRTEDTITRAGFRVDDARREWTFPAWVPVPVAEFAIGVARRP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2133--100% (210)methyltransferase type 12

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1178-5e-7565.37% (205) hypothetical protein Mb1178
M. tuberculosis H37RvRv1147-5e-7565.37% (205) hypothetical protein Rv1147
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1291-2e-6256.52% (207) hypothetical protein MAB_1291
M. marinum MMMAR_4303-4e-7766.50% (206) hypothetical protein MMAR_4303
M. avium 104MAV_1288-1e-7363.77% (207) hypothetical protein MAV_1288
M. smegmatis MC2 155MSMEG_5176-1e-8171.84% (206) methyltransferase type 11
M. thermoresistible (build 8)TH_1988-1e-5872.08% (154) methyltransferase type 11
M. ulcerans Agy99MUL_0991-3e-7766.50% (206) hypothetical protein MUL_0991
M. vanbaalenii PYR-1Mvan_4571-9e-9981.90% (210) methyltransferase type 12

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2133|M.gilvum_PYR-GCK          -------MSDVVDNPFFARLWTAMSSREPESLRRLRRDNLAGLTGRVLEV
Mvan_4571|M.vanbaalenii_PYR-1       -------MNDSVDNPFFARLWTLMSSREPESLRRLRRENLAGLTGRVLEV
MSMEG_5176|M.smegmatis_MC2_155      MPPTDAAQPEPVDNPFFAWLWKTLSTHETESVRRMRAENLAGLSGRVLEV
TH_1988|M.thermoresistible__bu      -------MTSTVDNPFFARMWTWLSSHEPEAMRQRREQLLAGLSGRVLEV
Mb1178|M.bovis_AF2122/97            MTSGAAASASRVDHPLFARIWPVVAAHEAEAIRALRRENLAGLSGRVLEV
Rv1147|M.tuberculosis_H37Rv         MTSGAAASASRVDHPLFARIWPVVAAHEAEAIRALRRENLAGLSGRVLEV
MMAR_4303|M.marinum_M               MTS----LAKNIDHPFFARIWPFIVAHEAEPVRALRRENLAGLSGRVLEI
MUL_0991|M.ulcerans_Agy99           MTS----LAKNIDHPFFARIWPFIVAHEAEPVRALRRENLAGLSGRVLEI
MAV_1288|M.avium_104                MTT------VVVDNPFFARIWPVVATHETAAVRALRRENVAGLTGRVLEV
MAB_1291|M.abscessus_ATCC_1997      MTT-----PVSFDNRFFSATWSAIARREPQEIKELRAENLRGLTGHVLEV
                                               .*: :*:  *  :  :*.  ::  * : : **:*:***:

Mflv_2133|M.gilvum_PYR-GCK          GAGTGTNFEFYPSTVTEVVAVEPERRLAVLAEQAAAGAAVPVTVSTDTVE
Mvan_4571|M.vanbaalenii_PYR-1       GAGTGTNFEFYPATVTEVVAVEPEHRLATLAQDAAARAAVPITVTTDTVE
MSMEG_5176|M.smegmatis_MC2_155      GAGTGTNFEFYPSTVDEVVAIEPERRLADVARQAAAKAPVPVSVTGDTIE
TH_1988|M.thermoresistible__bu      GAGTGTNFAFYPPGVTEVVAVEPEQRLVAVVRQAAAEAPVPVTVRAETVE
Mb1178|M.bovis_AF2122/97            GAGVGTNFAYYPVAVEQVIAMEPEPRLAAKARIAAADAPVPIVVTDKTVE
Rv1147|M.tuberculosis_H37Rv         GAGVGTNFAYYPVAVEQVIAMEPEPRLAAKARIAAADAPVPIVVTDKTVE
MMAR_4303|M.marinum_M               GAGMGTNFAFYPQTVTEVVAVEPEPHLALRARAAGEDAPIPVTVTADTAE
MUL_0991|M.ulcerans_Agy99           GAGMGTNFAFYPQTVTEVVAVEPEPHLALRARAAGEDAPIPVTVTADTAE
MAV_1288|M.avium_104                GAGIGTNFPLYPETVDEVIAVEPEPRLADRARAAAQVVPVRVVVTGETAE
MAB_1291|M.abscessus_ATCC_1997      GAGIGSNFLLYPNTVTAVTALEPESRLRPQAEDAAAGAAIPVTVTAGVFE
                                    *** *:**  **  *  * *:*** :*   .. *.  ..: : *   . *

Mflv_2133|M.gilvum_PYR-GCK          QFADA--KPFDAVVCSLVLCSVDDPEQVVSQLFSVLKPGGELRYLEHVAS
Mvan_4571|M.vanbaalenii_PYR-1       EFTDA--EPFDAVVCSLVLCSVDKPEDVVAELLSMLKPGGQLRYLEHIAA
MSMEG_5176|M.smegmatis_MC2_155      TFASA--QPFDAVVCSLVLCSVDDPEQVVGQLYSLLRPGGELRYLEHVAG
TH_1988|M.thermoresistible__bu      NFDSS--EPFDAVVCTLVLCSVDDPAGVVRQLFSLLRPGGELRYLEHIAS
Mb1178|M.bovis_AF2122/97            EFRDT--ETFDAVVCSLVLCSVSDPGAVLAHLRSLLRRGGELRYLEHVAS
Rv1147|M.tuberculosis_H37Rv         EFRDT--ETFDAVVCSLVLCSVSDPGAVLAHLRSLLRRGGELRYLEHVAS
MMAR_4303|M.marinum_M               QFSDQ--DPFDAVVCSLVLCSVTDQLGVLQHLRSLLRPGGELRYLEHIAS
MUL_0991|M.ulcerans_Agy99           QFSDQ--DPFDAVVCSLVLCSVTDQLGVLQHLRSLLRPGGELRYLEHIAS
MAV_1288|M.avium_104                AVGGD--EPFDAVVCSLVLCSVRDPQNVLRRLYSLLRPGGQLRYLEHIAS
MAB_1291|M.abscessus_ATCC_1997      DLAVTGEDRFDAVVCSLVLCSVGDPDRAAAQAFEVLKPGGEVRFFEHVAH
                                     .     . ******:****** .   .  .  .:*: **::*::**:* 

Mflv_2133|M.gilvum_PYR-GCK          DGAARGRLQRFADATFWPRLLGNCHTHRRTEDTITRAGFRVDDARREWTF
Mvan_4571|M.vanbaalenii_PYR-1       EGG-RARLQRFADATVWPRLLGNCHTHRHTEETIVGAGFRVRDARREWTF
MSMEG_5176|M.smegmatis_MC2_155      TGF-QARLQRLADATVWPKLFGGCHTHRHTEQVIASSGFGVRGRRREQVL
TH_1988|M.thermoresistible__bu      AGA-RGRLQRFADXR-----------------------------------
Mb1178|M.bovis_AF2122/97            AGA-RGRVQRFVDATFWPRLAGNCHTHRHTERAILDAGFVVDSSRREWAF
Rv1147|M.tuberculosis_H37Rv         AGA-RGRVQRFVDATFWPRLAGNCHTHRHTERAILDAGFVVDSSRREWAF
MMAR_4303|M.marinum_M               AGA-RGRLQQFVDATFWPRIAGNCHTHRDTERVIKAAGFDVESTRREWTL
MUL_0991|M.ulcerans_Agy99           AGA-RGRLQQFVDATFWPRIAGNCHTHRDTERVIKAAGFDVESTRREWTL
MAV_1288|M.avium_104                AGA-RGRFQRFVDATLWPRLFGNCHTHRDTERSIVEAGFDVDASRREWTL
MAB_1291|M.abscessus_ATCC_1997      DGA-LGLVQRAVDATFWPRLFGNCHTHRDTLAAIERAGFTIEERRDDWLK
                                     *   . .*: .*                                     

Mflv_2133|M.gilvum_PYR-GCK          PAWVPVPVAEFAIGVARRP-
Mvan_4571|M.vanbaalenii_PYR-1       PRWVPLPVAEFAIGVAVKP-
MSMEG_5176|M.smegmatis_MC2_155      PAWVPVPTTEFAIGRAVRP-
TH_1988|M.thermoresistible__bu      --------------------
Mb1178|M.bovis_AF2122/97            PAWVPLPVSELALGRAHRT-
Rv1147|M.tuberculosis_H37Rv         PAWVPLPVSELALGRAHRT-
MMAR_4303|M.marinum_M               PTWAPVPVAELVLGRARRP-
MUL_0991|M.ulcerans_Agy99           PTWAPVPVAELVLGRARRP-
MAV_1288|M.avium_104                PAWSPMPVSELLLGRAHRPA
MAB_1291|M.abscessus_ATCC_1997      VMGIPMPSSSIVIGRAVKPA