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QLHKRDVVDVATSLLDDYGIADLSMRRLARELNVSPGALYWHFANKQQLLGAVADRILAAVDDVPAGWRD RIAGICAQLRDALLSHTDGAELVSASFAAGQSAAMTEVLGHLTAAAADAGVAPEHAELTARTVIYYVLGF TADEQSRLQWDAAGADVAQTVWAEDPSARFTFGLHLLVDGIAVHSRAGT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2792 | - | - | 100% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1989 | - | 1e-08 | 27.17% (173) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4778 | - | 8e-08 | 25.34% (146) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1047 | - | 2e-06 | 24.66% (146) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3625 | - | 6e-81 | 78.95% (190) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1019 | - | 2e-06 | 24.66% (146) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2685 | - | 7e-58 | 60.82% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 3e-09 | 27.67% (206) | putative regulatory protein |
| M. avium 104 | MAV_1586 | - | 7e-08 | 27.66% (141) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3193 | - | 1e-61 | 64.89% (188) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0654 | - | 3e-64 | 65.95% (185) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3622 | - | 4e-09 | 27.67% (206) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2792|M.vanbaalenii_PYR-1 --------------------------MQLHKRDVVDVATSLLDDYGIADL
Mflv_3625|M.gilvum_PYR-GCK --------------------------MQLSKRDVVDVATSLLDDYGIADL
MSMEG_3193|M.smegmatis_MC2_155 --------------------------MQLHKPDVVAAATKILDDHGIADL
TH_0654|M.thermoresistible__bu --------------------------VQLRKSDVVDAATAILDNYGIADL
MAB_2685|M.abscessus_ATCC_1997 ----MAITEPNKGRTAPPMSRLREERRALNRHDLVRRATAILDDYGIADL
MMAR_3679|M.marinum_M --------MFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MUL_3622|M.ulcerans_Agy99 MISIRTSYVFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
Mb1047|M.bovis_AF2122/97 ------------------------MTGTERRHQLIGIARSLFAERGYDGT
Rv1019|M.tuberculosis_H37Rv ------------------------MTGTERRHQLIGIARSLFAERGYDGT
MAV_1586|M.avium_104 -----------MAKQATADKRQRRERGSINPDDIITGAFELAEQVSIDNL
:: * : : . .
Mvan_2792|M.vanbaalenii_PYR-1 SMRRLARELNVSPGALYWHFANKQQLLGAVADRILAAVD----DVPAG--
Mflv_3625|M.gilvum_PYR-GCK SMRRLARELNVSAGALYWHFANKQQLLGAVADRILQPLT----PASGN--
MSMEG_3193|M.smegmatis_MC2_155 TMRRLARELDVTPGALYWHFANKQELLGAVADHILRTAR----TDTADLA
TH_0654|M.thermoresistible__bu TTRRLARELGVTAGALYWHFANKQELLGAVADRILTPVP----AGEPEPG
MAB_2685|M.abscessus_ATCC_1997 TMRRLARELDIAPSALYWHFANKQQLLGAVADHVLAPLAE---SDRRDAP
MMAR_3679|M.marinum_M SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKV---PAPTD-D
MUL_3622|M.ulcerans_Agy99 SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKV---PAPID-D
Mb1047|M.bovis_AF2122/97 SIEEIAQRANVSKPVVYEHFGGKEGLYAVVVDREMSALLDGITSSLTNNR
Rv1019|M.tuberculosis_H37Rv SIEEIAQRANVSKPVVYEHFGGKEGLYAVVVDREMSALLDGITSSLTNNR
MAV_1586|M.avium_104 SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFAT-PYVEASD
: :. . :* :. : * :.* :
Mvan_2792|M.vanbaalenii_PYR-1 WRDRIAGICAQLRDALLSHTDGAELVSASFAAG--QSAAMTEVLGHLTAA
Mflv_3625|M.gilvum_PYR-GCK WPERVRATCAQLRDALLSHTDGAELVSASLAAG--QSEVMTAVLARLAAA
MSMEG_3193|M.smegmatis_MC2_155 WREQIHESCRALRDALLSHTDGAELVSASFASG--QSVVITEIVEQLGRA
TH_0654|M.thermoresistible__bu WAERISSTAGRLRDALLSHTDGAELVSATFAAG--QSRVLDEILARFAAA
MAB_2685|M.abscessus_ATCC_1997 WQERIDFLCSALRDALLSHKDGAELVSASFASG--QTAHMITVLDRLAEA
MMAR_3679|M.marinum_M WRADVHAIATAMWETMRQHPNAIPLVLTRRTVS--ASSYM--VADRLIAA
MUL_3622|M.ulcerans_Agy99 WRADVHAIATAMWETMRQHPNAIPLVLTRRTVW--ASSYM--VADRLIAA
Mb1047|M.bovis_AF2122/97 SRVRVERVALALLTYVEERTDGFRIMIRDSPAS--ISSGTYSSLLNDAVS
Rv1019|M.tuberculosis_H37Rv SRVRVERVALALLTYVEERTDGFRIMIRDSPAS--ISSGTYSSLLNDAVS
MAV_1586|M.avium_104 WRETLRNHARLMRKTFMGNPILCDLILIRAALSPKAARLGAQEMEKAVAN
: . : . . :: . : .
Mvan_2792|M.vanbaalenii_PYR-1 AADAGVAPEHAELTARTVIYYVLG-----------FTADEQSRLQWDA--
Mflv_3625|M.gilvum_PYR-GCK AGDAGVASEHTDLVARTVIYYVLG-----------FTADEQSRLQWDA--
MSMEG_3193|M.smegmatis_MC2_155 ARAAGVSDADVDAAARTVIYYVLG-----------FTVDEQSRLQWDA--
TH_0654|M.thermoresistible__bu AAAAGLEGSRAVLAARTIVHYVLG-----------FTGDEQSRLQWDA--
MAB_2685|M.abscessus_ATCC_1997 AATAGLGAVPAALAARSIVYYVLG-----------YVADEQSRLQWDS--
MMAR_3679|M.marinum_M LGRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARI
MUL_3622|M.ulcerans_Agy99 LGRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARI
Mb1047|M.bovis_AF2122/97 QVSSILAGDFARRGLDPDLAPLYAQ---------ALVGSVSMTAQWWL--
Rv1019|M.tuberculosis_H37Rv QVSSILAGDFARRGLDPDLAPLYAQ---------ALVGSVSMTAQWWL--
MAV_1586|M.avium_104 LVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAIEDAVA
: : : .
Mvan_2792|M.vanbaalenii_PYR-1 ---AGADVA-QTVWAE-----DPSARFTFGLHLLVDGIAVHSRAGT----
Mflv_3625|M.gilvum_PYR-GCK ---AGAEVD-TTVWNE-----DPNARFAFGLRLLTDGIAAHSRTGS----
MSMEG_3193|M.smegmatis_MC2_155 ---VGALGDDQSMLTR-----DGTRQFRFGLQLLVDGLAAHGGGSEFTGF
TH_0654|M.thermoresistible__bu ---AGAEVA-EPPADD-----NPSARFAFGLNLLINGIAAEIDAAARKSE
MAB_2685|M.abscessus_ATCC_1997 ---AGALENGQSFLADGAGFADPSAQFGFGARLLVDGIGQLARQSSPIG-
MMAR_3679|M.marinum_M GGLAGAEHPHIAALAQASQRSTPAADFERALDILLAGIESFERRRDRR--
MUL_3622|M.ulcerans_Agy99 GGLAGAEHPHIAALAQASQRSTPAADFERALDILLAGIESFERRRDRR--
Mb1047|M.bovis_AF2122/97 ----DAREPKKEVVAA------------HLVNLVWNGLTHLEADPRLQDE
Rv1019|M.tuberculosis_H37Rv ----DAREPKKEVVAA------------HLVNLVWNGLTHLEADPRLQDE
MAV_1586|M.avium_104 IDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEEGKGAKA
: :
Mvan_2792|M.vanbaalenii_PYR-1 ------------------------
Mflv_3625|M.gilvum_PYR-GCK ------------------------
MSMEG_3193|M.smegmatis_MC2_155 SSAERSFE----------------
TH_0654|M.thermoresistible__bu ------------------------
MAB_2685|M.abscessus_ATCC_1997 ------------------------
MMAR_3679|M.marinum_M ------------------------
MUL_3622|M.ulcerans_Agy99 ------------------------
Mb1047|M.bovis_AF2122/97 ------------------------
Rv1019|M.tuberculosis_H37Rv ------------------------
MAV_1586|M.avium_104 GPSRQRKPAKSSAARGRTKAPANR