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QLHKPDVVAAATKILDDHGIADLTMRRLARELDVTPGALYWHFANKQELLGAVADHILRTARTDTADLAW REQIHESCRALRDALLSHTDGAELVSASFASGQSVVITEIVEQLGRAARAAGVSDADVDAAARTVIYYVL GFTVDEQSRLQWDAVGALGDDQSMLTRDGTRQFRFGLQLLVDGLAAHGGGSEFTGFSSAERSFE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3193 | - | - | 100% (205) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2225 | - | 4e-07 | 23.94% (213) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6537 | - | 6e-07 | 33.33% (69) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 6e-06 | 26.74% (86) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3625 | - | 1e-58 | 62.23% (188) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 6e-06 | 26.74% (86) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2685 | - | 2e-57 | 59.26% (189) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 4e-12 | 29.71% (138) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 6e-07 | 34.48% (87) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0654 | - | 4e-55 | 60.96% (187) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3622 | - | 1e-11 | 29.71% (138) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2792 | - | 1e-61 | 64.89% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3625|M.gilvum_PYR-GCK --------------------------MQLSKRDVVDVATSLLDDYGIADL
Mvan_2792|M.vanbaalenii_PYR-1 --------------------------MQLHKRDVVDVATSLLDDYGIADL
MSMEG_3193|M.smegmatis_MC2_155 --------------------------MQLHKPDVVAAATKILDDHGIADL
TH_0654|M.thermoresistible__bu --------------------------VQLRKSDVVDAATAILDNYGIADL
MAB_2685|M.abscessus_ATCC_1997 ----MAITEPNKGRTAPPMSRLREERRALNRHDLVRRATAILDDYGIADL
MMAR_3679|M.marinum_M --------MFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MUL_3622|M.ulcerans_Agy99 MISIRTSYVFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
Mb1388c|M.bovis_AF2122/97 -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
Rv1353c|M.tuberculosis_H37Rv -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
MAV_5055|M.avium_104 -----------------------MRRAGLKREAVVRAAVKIADAEGIEAI
: : * : : .: :
Mflv_3625|M.gilvum_PYR-GCK SMRRLARELNVSAGALYWHFANKQQLLGAVADRILQPLT-PASGN----W
Mvan_2792|M.vanbaalenii_PYR-1 SMRRLARELNVSPGALYWHFANKQQLLGAVADRILAAVD-DVPAG----W
MSMEG_3193|M.smegmatis_MC2_155 TMRRLARELDVTPGALYWHFANKQELLGAVADHILRTAR-TDTADLA--W
TH_0654|M.thermoresistible__bu TTRRLARELGVTAGALYWHFANKQELLGAVADRILTPVP-AGEPEPG--W
MAB_2685|M.abscessus_ATCC_1997 TMRRLARELDIAPSALYWHFANKQQLLGAVADHVLAPLAESDRRDAP--W
MMAR_3679|M.marinum_M SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAPTD-D--W
MUL_3622|M.ulcerans_Agy99 SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAPID-D--W
Mb1388c|M.bovis_AF2122/97 SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
Rv1353c|M.tuberculosis_H37Rv SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
MAV_5055|M.avium_104 SMRRVSQALGVTPMALYRYLPDKDALIDVVVDESLAVVPVPDPSG---SV
: :. *. ::* :. .: * :.* :
Mflv_3625|M.gilvum_PYR-GCK PERVRATCAQLRDALLSHTDGAELVSASLAAG--QSEVMTAVLARLAAAA
Mvan_2792|M.vanbaalenii_PYR-1 RDRIAGICAQLRDALLSHTDGAELVSASFAAG--QSAAMTEVLGHLTAAA
MSMEG_3193|M.smegmatis_MC2_155 REQIHESCRALRDALLSHTDGAELVSASFASG--QSVVITEIVEQLGRAA
TH_0654|M.thermoresistible__bu AERISSTAGRLRDALLSHTDGAELVSATFAAG--QSRVLDEILARFAAAA
MAB_2685|M.abscessus_ATCC_1997 QERIDFLCSALRDALLSHKDGAELVSASFASG--QTAHMITVLDRLAEAA
MMAR_3679|M.marinum_M RADVHAIATAMWETMRQHPNAIPLVLTRRTVS--ASSYM--VADRLIAAL
MUL_3622|M.ulcerans_Agy99 RADVHAIATAMWETMRQHPNAIPLVLTRRTVW--ASSYM--VADRLIAAL
Mb1388c|M.bovis_AF2122/97 RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
Rv1353c|M.tuberculosis_H37Rv RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
MAV_5055|M.avium_104 TAELLRCFGGLYDLLLDHPGLARAAGERPLEG----PFATRLGNNVLTLL
: : . : .: .
Mflv_3625|M.gilvum_PYR-GCK GDAGVASEHTDLVARTVIYYVLG-----------FTADEQSRLQWDA---
Mvan_2792|M.vanbaalenii_PYR-1 ADAGVAPEHAELTARTVIYYVLG-----------FTADEQSRLQWDA---
MSMEG_3193|M.smegmatis_MC2_155 RAAGVSDADVDAAARTVIYYVLG-----------FTVDEQSRLQWDA---
TH_0654|M.thermoresistible__bu AAAGLEGSRAVLAARTIVHYVLG-----------FTGDEQSRLQWDA---
MAB_2685|M.abscessus_ATCC_1997 ATAGLGAVPAALAARSIVYYVLG-----------YVADEQSRLQWDS---
MMAR_3679|M.marinum_M GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
MUL_3622|M.ulcerans_Agy99 GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
Mb1388c|M.bovis_AF2122/97 VTAGLSLEDAFDIYSAVSVHVRG-----SVVLDRLSRKSQSAGSGPSAIE
Rv1353c|M.tuberculosis_H37Rv VTAGLSLEDAFDIYSAVSVHVRG-----SVVLDRLSRKSQSAGSGPSAIE
MAV_5055|M.avium_104 QHNKIDEADAANLLVSAFSLTLG---------CALYRTSRSGRTASSRLS
: . * .:. :
Mflv_3625|M.gilvum_PYR-GCK --AGAEVD-TTVWNE----------DPNARFAFGLRLLTDGIAAHSRTGS
Mvan_2792|M.vanbaalenii_PYR-1 --AGADVA-QTVWAE----------DPSARFTFGLHLLVDGIAVHSRAGT
MSMEG_3193|M.smegmatis_MC2_155 --VGALGDDQSMLTR----------DGTRQFRFGLQLLVDGLAAHGGGSE
TH_0654|M.thermoresistible__bu --AGAEVA-EPPADD----------NPSARFAFGLNLLINGIAAEIDAAA
MAB_2685|M.abscessus_ATCC_1997 --AGALENGQSFLADGAGF-----ADPSAQFGFGARLLVDGIGQLARQSS
MMAR_3679|M.marinum_M GLAGAEHPHIAALAQASQR-----STPAADFERALDILLAGIESFERRRD
MUL_3622|M.ulcerans_Agy99 GLAGAEHPHIAALAQASQR-----STPAADFERALDILLAGIESFERRRD
Mb1388c|M.bovis_AF2122/97 HPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSS
Rv1353c|M.tuberculosis_H37Rv HPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSS
MAV_5055|M.avium_104 QVGDEAPAVRRLRGRLTVAS-----ADDTVFRDALTRLIAGYVTTAAKTG
* . :
Mflv_3625|M.gilvum_PYR-GCK -----------------------------
Mvan_2792|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_3193|M.smegmatis_MC2_155 FTGFSSAERSFE-----------------
TH_0654|M.thermoresistible__bu RKSE-------------------------
MAB_2685|M.abscessus_ATCC_1997 PIG--------------------------
MMAR_3679|M.marinum_M RR---------------------------
MUL_3622|M.ulcerans_Agy99 RR---------------------------
Mb1388c|M.bovis_AF2122/97 KAAGEVAVRRPTATADAPTPGARAKAVAR
Rv1353c|M.tuberculosis_H37Rv KAAGEVAVRRPTATADAPTPGARAKAVAR
MAV_5055|M.avium_104 GRRR-------------------------