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MAITEPNKGRTAPPMSRLREERRALNRHDLVRRATAILDDYGIADLTMRRLARELDIAPSALYWHFANKQ QLLGAVADHVLAPLAESDRRDAPWQERIDFLCSALRDALLSHKDGAELVSASFASGQTAHMITVLDRLAE AAATAGLGAVPAALAARSIVYYVLGYVADEQSRLQWDSAGALENGQSFLADGAGFADPSAQFGFGARLLV DGIGQLARQSSPIG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2685 | - | - | 100% (224) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1430c | - | 1e-22 | 37.18% (156) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0856c | - | 9e-18 | 32.00% (150) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 5e-09 | 24.12% (228) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3625 | - | 5e-55 | 56.85% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 5e-09 | 24.12% (228) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3679 | - | 2e-09 | 27.74% (137) | putative regulatory protein |
| M. avium 104 | MAV_1586 | - | 1e-07 | 27.78% (144) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3193 | - | 3e-57 | 59.26% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0654 | - | 1e-52 | 57.67% (189) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3622 | - | 4e-09 | 27.74% (137) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2792 | - | 1e-57 | 60.82% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3625|M.gilvum_PYR-GCK --------------------------MQLSKRDVVDVATSLLDDYGIADL
Mvan_2792|M.vanbaalenii_PYR-1 --------------------------MQLHKRDVVDVATSLLDDYGIADL
MSMEG_3193|M.smegmatis_MC2_155 --------------------------MQLHKPDVVAAATKILDDHGIADL
TH_0654|M.thermoresistible__bu --------------------------VQLRKSDVVDAATAILDNYGIADL
MAB_2685|M.abscessus_ATCC_1997 ----MAITEPNKGRTAPPMSRLREERRALNRHDLVRRATAILDDYGIADL
MMAR_3679|M.marinum_M --------MFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MUL_3622|M.ulcerans_Agy99 MISIRTSYVFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
Mb1388c|M.bovis_AF2122/97 -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
Rv1353c|M.tuberculosis_H37Rv -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
MAV_1586|M.avium_104 -----------MAKQATADKRQRRERGSINPDDIITGAFELAEQVSIDNL
: *: * : :: .: .*
Mflv_3625|M.gilvum_PYR-GCK SMRRLARELNVSAGALYWHFANKQQLLGAVADRILQPLT-PASGN----W
Mvan_2792|M.vanbaalenii_PYR-1 SMRRLARELNVSPGALYWHFANKQQLLGAVADRILAAVD-DVPAG----W
MSMEG_3193|M.smegmatis_MC2_155 TMRRLARELDVTPGALYWHFANKQELLGAVADHILRTAR-TDTADLA--W
TH_0654|M.thermoresistible__bu TTRRLARELGVTAGALYWHFANKQELLGAVADRILTPVP-AGEPEPG--W
MAB_2685|M.abscessus_ATCC_1997 TMRRLARELDIAPSALYWHFANKQQLLGAVADHVLAPLAESDRRDAP--W
MMAR_3679|M.marinum_M SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAPTD-D--W
MUL_3622|M.ulcerans_Agy99 SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAPID-D--W
Mb1388c|M.bovis_AF2122/97 SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
Rv1353c|M.tuberculosis_H37Rv SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
MAV_1586|M.avium_104 SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEASDW
: *. *. ::* :. .: :* ::* : *
Mflv_3625|M.gilvum_PYR-GCK PERVRATCAQLRDALLSHTDGAELVSASLAAG--QSEVMTAVLARLAAAA
Mvan_2792|M.vanbaalenii_PYR-1 RDRIAGICAQLRDALLSHTDGAELVSASFAAG--QSAAMTEVLGHLTAAA
MSMEG_3193|M.smegmatis_MC2_155 REQIHESCRALRDALLSHTDGAELVSASFASG--QSVVITEIVEQLGRAA
TH_0654|M.thermoresistible__bu AERISSTAGRLRDALLSHTDGAELVSATFAAG--QSRVLDEILARFAAAA
MAB_2685|M.abscessus_ATCC_1997 QERIDFLCSALRDALLSHKDGAELVSASFASG--QTAHMITVLDRLAEAA
MMAR_3679|M.marinum_M RADVHAIATAMWETMRQHPNAIPLVLTRRTVS--ASSYM--VADRLIAAL
MUL_3622|M.ulcerans_Agy99 RADVHAIATAMWETMRQHPNAIPLVLTRRTVW--ASSYM--VADRLIAAL
Mb1388c|M.bovis_AF2122/97 RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
Rv1353c|M.tuberculosis_H37Rv RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
MAV_1586|M.avium_104 RETLRNHARLMRKTFMGNPILCDLILIRAALSPKAARLGAQEMEKAVANL
: . : .:: : *: : : :
Mflv_3625|M.gilvum_PYR-GCK GDAGVASEHTDLVARTVIYYVLG-----------FTADEQSRLQWDA---
Mvan_2792|M.vanbaalenii_PYR-1 ADAGVAPEHAELTARTVIYYVLG-----------FTADEQSRLQWDA---
MSMEG_3193|M.smegmatis_MC2_155 RAAGVSDADVDAAARTVIYYVLG-----------FTVDEQSRLQWDA---
TH_0654|M.thermoresistible__bu AAAGLEGSRAVLAARTIVHYVLG-----------FTGDEQSRLQWDA---
MAB_2685|M.abscessus_ATCC_1997 ATAGLGAVPAALAARSIVYYVLG-----------YVADEQSRLQWDS---
MMAR_3679|M.marinum_M GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
MUL_3622|M.ulcerans_Agy99 GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
Mb1388c|M.bovis_AF2122/97 VTAGLSLEDAFDIYSAVSVHVRG-----SVVLDRLSRKSQSAGSGPSAIE
Rv1353c|M.tuberculosis_H37Rv VTAGLSLEDAFDIYSAVSVHVRG-----SVVLDRLSRKSQSAGSGPSAIE
MAV_1586|M.avium_104 VQAGLSPEDAFDTYSAISVHVRG-----SVVLQRLYEKNQSSDVGPRAIE
:*: : * * .:.
Mflv_3625|M.gilvum_PYR-GCK --AGAEVD-TTVWNE----------DPNARFAFGLRLLTDGIAAHSRTGS
Mvan_2792|M.vanbaalenii_PYR-1 --AGADVA-QTVWAE----------DPSARFTFGLHLLVDGIAVHSRAGT
MSMEG_3193|M.smegmatis_MC2_155 --VGALGDDQSMLTR----------DGTRQFRFGLQLLVDGLAAHGGGSE
TH_0654|M.thermoresistible__bu --AGAEVA-EPPADD----------NPSARFAFGLNLLINGIAAEIDAAA
MAB_2685|M.abscessus_ATCC_1997 --AGALENGQSFLADGAGF-----ADPSAQFGFGARLLVDGIGQLARQSS
MMAR_3679|M.marinum_M GLAGAEHPHIAALAQASQR-----STPAADFERALDILLAGIESFERRRD
MUL_3622|M.ulcerans_Agy99 GLAGAEHPHIAALAQASQR-----STPAADFERALDILLAGIESFERRRD
Mb1388c|M.bovis_AF2122/97 HPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSS
Rv1353c|M.tuberculosis_H37Rv HPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSS
MAV_1586|M.avium_104 DAVAIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEEGK
.. . * . :
Mflv_3625|M.gilvum_PYR-GCK ------------------------------
Mvan_2792|M.vanbaalenii_PYR-1 ------------------------------
MSMEG_3193|M.smegmatis_MC2_155 FTGFSSAERSFE------------------
TH_0654|M.thermoresistible__bu RKSE--------------------------
MAB_2685|M.abscessus_ATCC_1997 PIG---------------------------
MMAR_3679|M.marinum_M RR----------------------------
MUL_3622|M.ulcerans_Agy99 RR----------------------------
Mb1388c|M.bovis_AF2122/97 KAAGEVAVRRPTATADAPTPGARAKAVAR-
Rv1353c|M.tuberculosis_H37Rv KAAGEVAVRRPTATADAPTPGARAKAVAR-
MAV_1586|M.avium_104 GAKAGPSRQRKPAKSSAAR--GRTKAPANR