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M. tuberculosis H37Rv Rv1236 (sugA)

annotation: PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA
coordinates: 1378927 - 1379850
length: 307

VTSVEQRTATAVFSRTGSRMAERRLAFMLVAPAAMLMVAVTAYPIGYALWLSLQRNNLATPNDTAFIGLG
NYHTILIDRYWWTALAVTLAITAVSVTIEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASYSWY
YAWTPGTGYLANLLPYDSAPLTQQIPSLGIVVIAEVWKTTPFMSLLLLAGLALVPEDLLRAAQVDGASAW
RRLTKVILPMIKPAIVVALLFRTLDAFRIFDNIYVLTGGSNNTGSVSILGYDNLFKGFNVGLGSAISVLI
FGCVAVIAFIFIKLFGAAAPGGEPSGR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1236sugA-100% (307)PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA
M. tuberculosis H37RvRv2316uspA3e-3733.96% (268) sugar-transport integral membrane protein ABC transporter
M. tuberculosis H37RvRv2040c-3e-2827.17% (276) sugar-transport integral membrane protein ABC transporter

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1268sugA1e-173100.00% (307) sugar-transport integral membrane protein ABC transporter
M. gilvum PYR-GCKMflv_3852-2e-7653.07% (277) binding-protein-dependent transport systems inner membrane
M. leprae Br4923MLBr_01087-1e-13781.85% (292) putative ABC-transport protein, inner membrane component
M. abscessus ATCC 19977MAB_1373-1e-12776.63% (291) sugar ABC transporter, permease protein SugA
M. marinum MMMAR_4205sugA1e-14083.16% (297) sugar-transport integral membrane protein ABC transporter
M. avium 104MAV_1375sugA1e-14285.12% (289) ABC transporter, permease protein SugA
M. smegmatis MC2 155MSMEG_5060-1e-13578.50% (307) ABC transporter, permease protein SugA
M. thermoresistible (build 8)TH_4307-1e-13377.70% (296) PUTATIVE binding-protein-dependent transport systems inner
M. ulcerans Agy99MUL_4512sugA1e-12785.38% (260) sugar-transport integral membrane protein ABC transporter
M. vanbaalenii PYR-1Mvan_2543-3e-7552.71% (277) binding-protein-dependent transport systems inner membrane

CLUSTAL 2.0.9 multiple sequence alignment


Rv1236|M.tuberculosis_H37Rv         MTSVEQRTA------TAVFSRTGSRMAERRLAFMLVAPAAMLMVAVTAYP
Mb1268|M.bovis_AF2122/97            MTSVEQRTA------TAVFSRTGSRMAERRLAFMLVAPAAMLMVAVTAYP
MAV_1375|M.avium_104                -----------------MLGRT----SEQRLALVLVAPAAILMLAVTAYP
MMAR_4205|M.marinum_M               ---------------MTALMRSRGRRAERRLAFALVAPATILMLLVIGYP
MUL_4512|M.ulcerans_Agy99           ---------------MTAFLRSRGRRAERRLAFALVAPATILMLLVIGYP
MLBr_01087|M.leprae_Br4923          ---MTAVVG------KSWHVRASSVQPEQRLAFLLVTPAAMLMLVVTAYP
MSMEG_5060|M.smegmatis_MC2_155      ---MTAAVT-----PSASAVASDDKKSERRLAFWLIAPAVLLMLAVTAYP
TH_4307|M.thermoresistible__bu      ---MTAAAEKADPTPAAAVARTDDTRSERRLAYWLIAPAVLLMVAVTGYP
MAB_1373|M.abscessus_ATCC_1997      ---MTDRTS------------SEGKRAERRLGLLLIAPAALLMLAVTAYP
Mflv_3852|M.gilvum_PYR-GCK          ---MTAPADAPIQKDPGKPSVSERAKGERRLGLYLTLPSYVVMLLVTAYP
Mvan_2543|M.vanbaalenii_PYR-1       ---MTALHEAPIQKDPGTPAVSERARGERRLGIYLTLPSYVVMLLVTAYP
                                                         :     *:**.  *  *: ::*: * .**

Rv1236|M.tuberculosis_H37Rv         IGYALWLSLQRNNLATPNDTAFIGLGNYHTILIDRYWWTALAVTLAITAV
Mb1268|M.bovis_AF2122/97            IGYALWLSLQRNNLATPNDTAFIGLGNYHTILIDRYWWTALAVTLAITAV
MAV_1375|M.avium_104                IGYAVWLSLQRNNLAAPHDTAFVGLSNYATILSDRYWWTALAVTLGITVV
MMAR_4205|M.marinum_M               IGYAMWLSLQRNNLATPNETRFIGLGNYQTILVDRYWWTALAVTAAITVV
MUL_4512|M.ulcerans_Agy99           IGYAMWLSLQRNNLATPNETRFIGLGNYQTILVDRYWWTALAVTAAITVV
MLBr_01087|M.leprae_Br4923          IGYAVWLSLQRYSLATPNETVFIGLGNYQTILTDPYWWTALAVTLAITVV
MSMEG_5060|M.smegmatis_MC2_155      IGYAVWLSLQRYNLAEPHDTEFIGLANYVTVLTDGYWWTAFAVTLGITVV
TH_4307|M.thermoresistible__bu      IAYAVWLSLLRYNLAQPDDVSFVGLENYVTVLTDEYWWTAFAVTLGITVV
MAB_1373|M.abscessus_ATCC_1997      ICYAIWLSVQKYSFASPQDRKFVWFDNYITVLSDRYWWSALVVTLVITVI
Mflv_3852|M.gilvum_PYR-GCK          LGYALVLSLYNFRLTDPEGRSFVGLGNYLVILTDPIWWNDFVTTLAITVV
Mvan_2543|M.vanbaalenii_PYR-1       LGYALVLSLYNFRLTDPEGRSFVGLSNYLVILTDPLWWNDFVTTLAITVV
                                    : **: **: .  :: *.   *: : ** .:* *  **. :..*  **.:

Rv1236|M.tuberculosis_H37Rv         SVTIEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASYSWYYAWT
Mb1268|M.bovis_AF2122/97            SVTIEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASYSWYYAWT
MAV_1375|M.avium_104                SVSAEFVLGLALALVMHRTLVGKGLVRTAVLIPYGIVTAVASYSWYYAWT
MMAR_4205|M.marinum_M               SVACEFVLGLALALVMHRSLVAKGLVRTAVLVPYGIVTVVASYSWYYAWT
MUL_4512|M.ulcerans_Agy99           SVACEFVLGLALALVMHRSLVAKGLVRTAVLVPYGIVTVVASYSWYYAWT
MLBr_01087|M.leprae_Br4923          SVSIEFILGLMLALVMHRTLLGKSLVRIAVLIPYSIVTVVASYSWYYAWT
MSMEG_5060|M.smegmatis_MC2_155      SVAIEFALGLALALVMHRTIFGKGAVRTAILIPYGIVTVAASYSWYYAWT
TH_4307|M.thermoresistible__bu      SVAIEFVLGLALALVMHRTIFGKGVVRTAILIPYGIVTVAASYSWYYAWT
MAB_1373|M.abscessus_ATCC_1997      SVLIELVLGLALALVMHRTIFGRGVVRTAVLIPYGIVTVAASYSWYYAWT
Mflv_3852|M.gilvum_PYR-GCK          TVAIELVLGFWFAFVMLRIVRGRGPLRTAILIPYGIVTVVSAFIWRYAFA
Mvan_2543|M.vanbaalenii_PYR-1       TVAIELVLGFWFAFVMLRIVRGRGPLRTAILIPYGIVTVVSAFIWRYAFA
                                    :*  *: **: :*:** * : .:. :* *:*:**.***..::: * **::

Rv1236|M.tuberculosis_H37Rv         PGTGYLANLLPYDSAPLT-QQIPSLGIVVIAEVWKTTPFMSLLLLAGLAL
Mb1268|M.bovis_AF2122/97            PGTGYLANLLPYDSAPLT-QQIPSLGIVVIAEVWKTTPFMSLLLLAGLAL
MAV_1375|M.avium_104                PGTGYLANLLPHGSAPLT-AQIPSLAIVVLAEVWKTTPFMSLLLLAGLAL
MMAR_4205|M.marinum_M               PGTGYLANLLPQGSAPLT-QQIPSLGIVVIAEVWKTTPFMSLLLLAGLAM
MUL_4512|M.ulcerans_Agy99           PGTGYLANLLPQGIAPLT-QQIPSLGIVVIAEVWKTTPFMSLLLLAGLAM
MLBr_01087|M.leprae_Br4923          PGTGYLASLLPQGSVPLT-EQIPSLSIVIIVEVWKTTPFMSLLLLVGLAL
MSMEG_5060|M.smegmatis_MC2_155      PGTGYLANLLPEGSAPLT-DQLPSLAIVVLAEVWKTTPFMALLLLAGLAL
TH_4307|M.thermoresistible__bu      PGTGYLANLLPDGSAPLT-QQLPSLAIVVLAEVWKTTPFMALLLLAGLAL
MAB_1373|M.abscessus_ATCC_1997      PGTGYLANLLPAGSAPLT-QQIPSLAVVILAEVWKTTPFMALLLLAGLAL
Mflv_3852|M.gilvum_PYR-GCK          IDSGFVNQWLNLTDFDWFGDRWSAIFVICLSEIWKTTPFISLLLLAGLVQ
Mvan_2543|M.vanbaalenii_PYR-1       IDSGFVNQWLNLTEFDWFGDRWSAIFVICLSEIWKTTPFISLLLLAGLVQ
                                     .:*:: . *          : .:: :: : *:******::****.**. 

Rv1236|M.tuberculosis_H37Rv         VPEDLLRAAQVDGASAWRRLTKVILPMIKPAIVVALLFRTLDAFRIFDNI
Mb1268|M.bovis_AF2122/97            VPEDLLRAAQVDGASAWRRLTKVILPMIKPAIVVALLFRTLDAFRIFDNI
MAV_1375|M.avium_104                VPEDLLKAAQVDGAGAWRRLTRVTLPIIKPAVVVALLFRTLDAFRIFDNI
MMAR_4205|M.marinum_M               VPEDLLQAAQVDGAGAWRRLTKIILPLIKPAVLVALLFRTLDAFRIFDNI
MUL_4512|M.ulcerans_Agy99           VPEDLLQAAQVDGAGAWRRLTKIILPLIKPAVLVALLFRTLDAFRIFDNI
MLBr_01087|M.leprae_Br4923          VPEDLLKAAQMDGAGAWRRLTKIILPIIKPAVMVALLFRTLDAFRIFDNI
MSMEG_5060|M.smegmatis_MC2_155      VPQDLLNAAQVDGAGPWKRLTKVILPMIKPAILVALLFRTLDAFRIFDNI
TH_4307|M.thermoresistible__bu      VPQELLNAAQMDGANAWQRLVKIILPMIKPAILVALLFRTLDAFRIFDNI
MAB_1373|M.abscessus_ATCC_1997      VPDDLLKAAQVDGANGWSRLIRVTVPIMKPAILVALLFRTLDAFRIFDNI
Mflv_3852|M.gilvum_PYR-GCK          VPEDMQEAAKVDGATAWQRLWKITLPNMKAAIMVALLFRTLDAWRIFDNP
Mvan_2543|M.vanbaalenii_PYR-1       VPEDMQEAAKVDGATAWQRLWKITLPNMKAAIMVALLFRTLDAWRIFDNP
                                    **::: .**::***  * ** :: :* :*.*::**********:***** 

Rv1236|M.tuberculosis_H37Rv         YVLTGGSNNTGSVSILGYDNLFKGFNVGLGSA----------------IS
Mb1268|M.bovis_AF2122/97            YVLTGGSNNTGSVSILGYDNLFKGFNVGLGSA----------------IS
MAV_1375|M.avium_104                YVLTNGANNTGSVSMLGYDNLFKGFNVGLGSA----------------IS
MMAR_4205|M.marinum_M               YVLTGGDNDTASVSILGYDNLFKGFNVGLGSA----------------IS
MUL_4512|M.ulcerans_Agy99           YVLTGGDNDTASVSILGYDNLFKGFNVGLAVQGIQCGPRFGDQRVDLRLC
MLBr_01087|M.leprae_Br4923          YVLTRGVNNTDSVSILGYDNLFKGFNVGLGSA----------------IS
MSMEG_5060|M.smegmatis_MC2_155      YILTGGSNDTGSVSILGYDNLFKAFNVGLGSA----------------IS
TH_4307|M.thermoresistible__bu      YILTGGANNTGSVSILGYNNLFKAFNLGLGSA----------------IS
MAB_1373|M.abscessus_ATCC_1997      YVLTGGSNNTGSVSILGYDNLFKAFNVGLGSA----------------IS
Mflv_3852|M.gilvum_PYR-GCK          YVMTAGANNTETISFLAYRQNVTLVNLGMGSA----------------VS
Mvan_2543|M.vanbaalenii_PYR-1       YVMTAGANNTETISFLAYRQNVTLVNLGMGSA----------------VS
                                    *::* * *:* ::*:*.* : .. .*:*:.                  :.

Rv1236|M.tuberculosis_H37Rv         VLIFGCVAVIAFIFIKLFGA----AAPGGEPSGR----------------
Mb1268|M.bovis_AF2122/97            VLIFGCVAVIAFIFIKLFGA----AAPGGEPSGR----------------
MAV_1375|M.avium_104                VLIFGCVGLIALVFVKVFGA----AAPGGDVDGR----------------
MMAR_4205|M.marinum_M               VLIFGCVTLIAVVFITLFGAHQFHSAPGGVTDAR----------------
MUL_4512|M.ulcerans_Agy99           HSHCGCLHHAVRRPSIRFCARWCDRCALRLGPCRRVAGGERSGWPSTPWS
MLBr_01087|M.leprae_Br4923          VLIFGCVALIAVIFIKVFGV----VAPGGDSNGY----------------
MSMEG_5060|M.smegmatis_MC2_155      VLIFLSVAIIAFIYIKIFGA----AAPGSDEEVR----------------
TH_4307|M.thermoresistible__bu      VLIFLCVAVIAFIYIKIFGT----SAPGSDAERS----------------
MAB_1373|M.abscessus_ATCC_1997      VLIFLCVAIIAVIFIKGFGA----SAPTTDGEEARR--------------
Mflv_3852|M.gilvum_PYR-GCK          VLLFLSVVAIAWIFIKVFKT----DLSQVRGDQ-----------------
Mvan_2543|M.vanbaalenii_PYR-1       VLLFLSVVGIAWIFIKVFKT----DLSQVRGDQ-----------------
                                         .:   .      * .      .                       

Rv1236|M.tuberculosis_H37Rv         -----------
Mb1268|M.bovis_AF2122/97            -----------
MAV_1375|M.avium_104                -----------
MMAR_4205|M.marinum_M               -----------
MUL_4512|M.ulcerans_Agy99           WSTPCSRCCGS
MLBr_01087|M.leprae_Br4923          -----------
MSMEG_5060|M.smegmatis_MC2_155      -----------
TH_4307|M.thermoresistible__bu      -----------
MAB_1373|M.abscessus_ATCC_1997      -----------
Mflv_3852|M.gilvum_PYR-GCK          -----------
Mvan_2543|M.vanbaalenii_PYR-1       -----------