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KFKYGMLMPLLALFAVAVGFPLCYAAYLSVTDYKLTDREPPDFVGTANFATALSNPAFWEAFATTATYVV IAVCGELVIGFALALALHQQRWAKDLSRAIVLAPMFITPIAVGLIFRFLLNDQIGAVPALLHAVGADHDF FGSGRALLTLAFIDIWQWTPFMVLLILAGLESMPKQPMEAARVDGAGPVYRLRRVLIPMLAPVLTVAVLL RGLDALRVFEYVYATTRGGPGTETQTLQYYMYLEGIQFFRLAQASAMAFIVLVLVLAVIVVAFRTMERTR ERTPSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3110 | - | - | 100% (287) | binding-protein-dependent transport systems inner membrane component |
| M. smegmatis MC2 155 | MSMEG_3267 | - | 1e-43 | 33.99% (253) | transporter |
| M. smegmatis MC2 155 | MSMEG_5573 | - | 1e-40 | 33.09% (272) | sugar ABC transporter permease protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1268 | sugA | 4e-32 | 30.77% (273) | sugar-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3776 | - | 1e-116 | 70.21% (282) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv1236 | sugA | 5e-32 | 30.77% (273) | sugar-transport integral membrane protein ABC transporter |
| M. leprae Br4923 | MLBr_01087 | - | 6e-36 | 30.45% (266) | putative ABC-transport protein, inner membrane component |
| M. abscessus ATCC 19977 | MAB_1373 | - | 9e-37 | 34.33% (268) | sugar ABC transporter, permease protein SugA |
| M. marinum M | MMAR_4205 | sugA | 5e-36 | 31.73% (271) | sugar-transport integral membrane protein ABC transporter |
| M. avium 104 | MAV_1375 | sugA | 2e-34 | 33.46% (266) | ABC transporter, permease protein SugA |
| M. thermoresistible (build 8) | TH_2010 | - | 4e-41 | 31.77% (277) | sugar ABC transporter permease protein |
| M. ulcerans Agy99 | MUL_2126 | ugpA | 1e-34 | 33.93% (280) | SN-glycerol-3-phosphate transport integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_2623 | - | 1e-116 | 71.02% (283) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3776|M.gilvum_PYR-GCK -----------------------------------MKFQHGMVAPLVALF
Mvan_2623|M.vanbaalenii_PYR-1 -------------------------------MMPSLRFQHGMVAPLAALF
MSMEG_3110|M.smegmatis_MC2_155 -----------------------------------MKFKYGMLMPLLALF
Mb1268|M.bovis_AF2122/97 -------------MTSVEQRTATAVFSRTGSRMAERRLAFMLVAPAAMLM
Rv1236|M.tuberculosis_H37Rv -------------MTSVEQRTATAVFSRTGSRMAERRLAFMLVAPAAMLM
MMAR_4205|M.marinum_M -------------MT---------ALMRSRGRRAERRLAFALVAPATILM
MAV_1375|M.avium_104 ----------------------------MLGRTSEQRLALVLVAPAAILM
MLBr_01087|M.leprae_Br4923 -------------MTAVVG---KSWHVRASSVQPEQRLAFLLVTPAAMLM
MAB_1373|M.abscessus_ATCC_1997 -------------MTDR---------TSSEGKRAERRLGLLLIAPAALLM
TH_2010|M.thermoresistible__bu MTAIAPGASEHLTGSEADRVARIKHAKQQGVSRAEGWRRRGPLLPALIFM
MUL_2126|M.ulcerans_Agy99 ---------------------MTTTRPRRNRSWRDYALFVALVGPNLALL
: * ::
Mflv_3776|M.gilvum_PYR-GCK VGVVGFPLGYAAYLSVTDYKLTDQGAPDIVGADNFVATFGDSGFWNAFGT
Mvan_2623|M.vanbaalenii_PYR-1 VGVVGFPLGYAAYLSVTDYKLTDRGAPNLVGADNYVAAFSDGAFWGAFGT
MSMEG_3110|M.smegmatis_MC2_155 AVAVGFPLCYAAYLSVTDYKLTDREPPDFVGTANFATALSNPAFWEAFAT
Mb1268|M.bovis_AF2122/97 VAVTAYPIGYALWLSLQRNNLATPNDTAFIGLGNYHTILIDRYWWTALAV
Rv1236|M.tuberculosis_H37Rv VAVTAYPIGYALWLSLQRNNLATPNDTAFIGLGNYHTILIDRYWWTALAV
MMAR_4205|M.marinum_M LLVIGYPIGYAMWLSLQRNNLATPNETRFIGLGNYQTILVDRYWWTALAV
MAV_1375|M.avium_104 LAVTAYPIGYAVWLSLQRNNLAAPHDTAFVGLSNYATILSDRYWWTALAV
MLBr_01087|M.leprae_Br4923 LVVTAYPIGYAVWLSLQRYSLATPNETVFIGLGNYQTILTDPYWWTALAV
MAB_1373|M.abscessus_ATCC_1997 LAVTAYPICYAIWLSVQKYSFASPQDRKFVWFDNYITVLSDRYWWSALVV
TH_2010|M.thermoresistible__bu IIVTQVPFLFTLYFSTLSWNLVRPGSREFVGFQNYVDVVQDSTFWQVAVN
MUL_2126|M.ulcerans_Agy99 LLFVYRPLVDNIRLSFFDWNISDP-TAEFVGFSNYIEWFSRPDTRQIVAN
*: :* .: :: *: .
Mflv_3776|M.gilvum_PYR-GCK TALYVLVAVGLELVIGLAIALALQKQRWARDLTRSMLLAPMFITPIAVGL
Mvan_2623|M.vanbaalenii_PYR-1 TALYVLVAVGLELVIGLAIALALQKQRWAKDLTRSMLLAPMFITPIAVGL
MSMEG_3110|M.smegmatis_MC2_155 TATYVVIAVCGELVIGFALALALHQQRWAKDLSRAIVLAPMFITPIAVGL
Mb1268|M.bovis_AF2122/97 TLAITAVSVTIEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASY
Rv1236|M.tuberculosis_H37Rv TLAITAVSVTIEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASY
MMAR_4205|M.marinum_M TAAITVVSVACEFVLGLALALVMHRSLVAKGLVRTAVLVPYGIVTVVASY
MAV_1375|M.avium_104 TLGITVVSVSAEFVLGLALALVMHRTLVGKGLVRTAVLIPYGIVTAVASY
MLBr_01087|M.leprae_Br4923 TLAITVVSVSIEFILGLMLALVMHRTLLGKSLVRIAVLIPYSIVTVVASY
MAB_1373|M.abscessus_ATCC_1997 TLVITVISVLIELVLGLALALVMHRTIFGRGVVRTAVLIPYGIVTVAASY
TH_2010|M.thermoresistible__bu SVLIIVVTVLVSVLLGLGLALLLDRVFLGRGIVRTLLITPFLVTPVAGAL
MUL_2126|M.ulcerans_Agy99 TAIFTTAAVAGSMVLGLLLAMLLDQPLRGRNLVRSTVFAPFVISGAAVGL
: :* ..::*: :*: :.: .:.: * :: * : . .
Mflv_3776|M.gilvum_PYR-GCK TFRFLLN-DQLGAIPAMLHAIGIDYDFFGPGR--ALYTLAFIDVWQWTPF
Mvan_2623|M.vanbaalenii_PYR-1 TFRFLLN-DQLGAIPAMLDAIGVEYDFFGPGR--ALFTLAFIDVWQWTPF
MSMEG_3110|M.smegmatis_MC2_155 IFRFLLN-DQIGAVPALLHAVGADHDFFGSGR--ALLTLAFIDIWQWTPF
Mb1268|M.bovis_AF2122/97 SWYYAWT-PGTGYLANLLPYDSAPLTQQIP----SLGIVVIAEVWKTTPF
Rv1236|M.tuberculosis_H37Rv SWYYAWT-PGTGYLANLLPYDSAPLTQQIP----SLGIVVIAEVWKTTPF
MMAR_4205|M.marinum_M SWYYAWT-PGTGYLANLLPQGSAPLTQQIP----SLGIVVIAEVWKTTPF
MAV_1375|M.avium_104 SWYYAWT-PGTGYLANLLPHGSAPLTAQIP----SLAIVVLAEVWKTTPF
MLBr_01087|M.leprae_Br4923 SWYYAWT-PGTGYLASLLPQGSVPLTEQIP----SLSIVIIVEVWKTTPF
MAB_1373|M.abscessus_ATCC_1997 SWYYAWT-PGTGYLANLLPAGSAPLTQQIP----SLAVVILAEVWKTTPF
TH_2010|M.thermoresistible__bu MWKTAMLDPVFGIVNWLLSPFGVHQVDWVSRF--PLTSVMINLVWQWTPF
MUL_2126|M.ulcerans_Agy99 AAQFVFD-PHFGLVQDLLHRVGVNAPDFYQDTPWALFMVTVTYVWKNLGY
* : :* . .* : . :*: :
Mflv_3776|M.gilvum_PYR-GCK MVLLLLAGLESIPKEPLDAARVDGARGLYVLRRVTLPLLAPVLVVAILLR
Mvan_2623|M.vanbaalenii_PYR-1 MVLLLLAGLESIPKEPLDAARLDGASGLYVLRRVTLPLLAPVLVVAILLR
MSMEG_3110|M.smegmatis_MC2_155 MVLLILAGLESMPKQPMEAARVDGAGPVYRLRRVLIPMLAPVLTVAVLLR
Mb1268|M.bovis_AF2122/97 MSLLLLAGLALVPEDLLRAAQVDGASAWRRLTKVILPMIKPAIVVALLFR
Rv1236|M.tuberculosis_H37Rv MSLLLLAGLALVPEDLLRAAQVDGASAWRRLTKVILPMIKPAIVVALLFR
MMAR_4205|M.marinum_M MSLLLLAGLAMVPEDLLQAAQVDGAGAWRRLTKIILPLIKPAVLVALLFR
MAV_1375|M.avium_104 MSLLLLAGLALVPEDLLKAAQVDGAGAWRRLTRVTLPIIKPAVVVALLFR
MLBr_01087|M.leprae_Br4923 MSLLLLVGLALVPEDLLKAAQMDGAGAWRRLTKIILPIIKPAVMVALLFR
MAB_1373|M.abscessus_ATCC_1997 MALLLLAGLALVPDDLLKAAQVDGANGWSRLIRVTVPIMKPAILVALLFR
TH_2010|M.thermoresistible__bu MMLLILAGLQSMPRDILEAGRVDGAGTFQLFRELTLPHLRRFIELGAVLG
MUL_2126|M.ulcerans_Agy99 TCVIYLAALQGVRRDLLEAAEIDGASRWTSFRRVLLPQLRPTTFFLSITV
:: *..* : : : *..:*** : .: :* : . :
Mflv_3776|M.gilvum_PYR-GCK SLDAMKVFEYVFATTRGGP-GTETETLQYFIYQTGIQFFRLGSASSMAFV
Mvan_2623|M.vanbaalenii_PYR-1 CLDAMKVFEYVFATTRGGP-GTETETLQYFIYQTGIQFFRLGSASSMAFI
MSMEG_3110|M.smegmatis_MC2_155 GLDALRVFEYVYATTRGGP-GTETQTLQYYMYLEGIQFFRLAQASAMAFI
Mb1268|M.bovis_AF2122/97 TLDAFRIFDNIYVLTGGSN-NTGS--VSILGYDNLFKGFNVGLGSAISVL
Rv1236|M.tuberculosis_H37Rv TLDAFRIFDNIYVLTGGSN-NTGS--VSILGYDNLFKGFNVGLGSAISVL
MMAR_4205|M.marinum_M TLDAFRIFDNIYVLTGGDN-DTAS--VSILGYDNLFKGFNVGLGSAISVL
MAV_1375|M.avium_104 TLDAFRIFDNIYVLTNGAN-NTGS--VSMLGYDNLFKGFNVGLGSAISVL
MLBr_01087|M.leprae_Br4923 TLDAFRIFDNIYVLTRGVN-NTDS--VSILGYDNLFKGFNVGLGSAISVL
MAB_1373|M.abscessus_ATCC_1997 TLDAFRIFDNIYVLTGGSN-NTGS--VSILGYDNLFKAFNVGLGSAISVL
TH_2010|M.thermoresistible__bu AIYLVNTFDPIYMMTQGGP-GTASSNLPFYIYQRAFLGFDIGQAAAMGVI
MUL_2126|M.ulcerans_Agy99 LINSLQVFDVINVMTRGGPEGTGTTTMVYQVYLETFRNFRAGYGATIATM
: .. *: : * * .* : : * : * . .:::. :
Mflv_3776|M.gilvum_PYR-GCK VLIVVLAAIVFAFRRMDR------AREAGIR-
Mvan_2623|M.vanbaalenii_PYR-1 VLVVVLAVIVIAFRRMER------TKSR----
MSMEG_3110|M.smegmatis_MC2_155 VLVLVLAVIVVAFRTMER------TRERTPSR
Mb1268|M.bovis_AF2122/97 IFGCVAVIAFIFIKLFGA----AAPGGEPSGR
Rv1236|M.tuberculosis_H37Rv IFGCVAVIAFIFIKLFGA----AAPGGEPSGR
MMAR_4205|M.marinum_M IFGCVTLIAVVFITLFGAHQFHSAPGGVTDAR
MAV_1375|M.avium_104 IFGCVGLIALVFVKVFGA----AAPGGDVDGR
MLBr_01087|M.leprae_Br4923 IFGCVALIAVIFIKVFGV----VAPGGDSNGY
MAB_1373|M.abscessus_ATCC_1997 IFLCVAIIAVIFIKGFGAS--APTTDGEEARR
TH_2010|M.thermoresistible__bu VVIFTIIIATFALRLIFR----SFTGKEEAA-
MUL_2126|M.ulcerans_Agy99 MFLFLLVVTYYQVRVMDR-------GQQQ---
:. . :