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SSHSYDTIGYEVDGHKATITLNRPEALNALSPHMINELRAAYDEAENDDDIWLMIVTGTGRAFCTGADVK EIPEDGKVIYERPYLSTYDQWEAPQEGTPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFD PHVSIGLVAAREMVRLARALPRSVALRMALMGKHERMSAERAYELGMITEVVEHDKLLERAHEIADIVNS NAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVVRTEDAQEGPLAFVEKRAPDWQCR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1984 | - | - | 100% (270) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_2610 | - | 5e-40 | 34.96% (266) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1983 | - | 2e-36 | 39.39% (231) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 3e-33 | 32.84% (268) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4360 | - | 1e-149 | 95.54% (269) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 3e-33 | 32.84% (268) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-30 | 31.23% (269) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 8e-35 | 34.34% (265) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4023 | echA11_1 | 1e-126 | 81.20% (266) | enoyl-CoA hydratase EchA11_1 |
| M. avium 104 | MAV_1582 | - | 1e-133 | 84.96% (266) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2219 | - | 1e-140 | 90.98% (266) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_4071 | - | 1e-132 | 83.70% (270) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_3888 | echA11_1 | 1e-125 | 81.20% (266) | enoyl-CoA hydratase EchA11_1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1984|M.vanbaalenii_PYR-1 --MSSHSYDTIGYEVDGHKATITLNRPEALNALSPHMINELRAAYDEAEN
Mflv_4360|M.gilvum_PYR-GCK -MSSSPSYDTITYDVDGHKATITLNRPEALNALSPHMVSELRAAYDEAEN
MSMEG_2219|M.smegmatis_MC2_155 ----MTTYDTIKYEVNGHTATITLNRPEALNALSPHMIGELRAAYAEAES
MAV_1582|M.avium_104 --MPVDSFDTIKYEVDGHTATITLNRPDALNALSPHMITELRAAYHEAEN
TH_4071|M.thermoresistible__bu --MSDTSYDTIKYEVDGHTATITLNRPDALNALSPHMITELRTAYDEAEN
MMAR_4023|M.marinum_M --MPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
MUL_3888|M.ulcerans_Agy99 MTMPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
Mb1099c|M.bovis_AF2122/97 -----MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDD
Rv1070c|M.tuberculosis_H37Rv -----MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDD
MLBr_02402|M.leprae_Br4923 -----MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDI
MAB_0836c|M.abscessus_ATCC_199 ----MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDH
: : :*:***. ***..::: :. * * :
Mvan_1984|M.vanbaalenii_PYR-1 DDDIWLMIVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
Mflv_4360|M.gilvum_PYR-GCK DDDVWLMIVTGNGRAFCTGADVKEIPEDGRVIYERPYLSTYDQWEAPQEG
MSMEG_2219|M.smegmatis_MC2_155 DDDIWLTVVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
MAV_1582|M.avium_104 DDRVWLLVVTGTGRAFCSGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
TH_4071|M.thermoresistible__bu DDNVWLLVVTGTGRAFCSGADVKEIPEDGKVINERPYLSTYEQWEAPQEG
MMAR_4023|M.marinum_M NDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPYLATYEQWEAPQEG
MUL_3888|M.ulcerans_Agy99 DDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPDLATYEQWEAPQEG
Mb1099c|M.bovis_AF2122/97 DPDIGAIIITGSAKAFAAGADIKE--------MADLTFADAFTADFFATW
Rv1070c|M.tuberculosis_H37Rv DPDIGAIIITGSAKAFAAGADIKE--------MADLTFADAFTADFFATW
MLBr_02402|M.leprae_Br4923 DPDVGAILITGSPKVFAAGADIKE--------MASLTFTDAFDADFFSAW
MAB_0836c|M.abscessus_ATCC_199 DDGIRAAILTGAGSAYCVGGDLSDG------WMVRDGSAPPLDPATIGKG
: : ::** .:. *.*:. :
Mvan_1984|M.vanbaalenii_PYR-1 TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
Mflv_4360|M.gilvum_PYR-GCK TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
MSMEG_2219|M.smegmatis_MC2_155 TPPFRTMAKPVIVAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
MAV_1582|M.avium_104 TPPFRTMAKPVLTAVNGICCGAGMDWVTTTDIVIASEQATFFDPHVSIGL
TH_4071|M.thermoresistible__bu TPPFRTMAKPVLAAINGICCGAGLDWVTTGDIVIASERATFFDPHVSIGL
MMAR_4023|M.marinum_M TPPFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASEAATFFDPHVSIGL
MUL_3888|M.ulcerans_Agy99 TPLFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASETATFFDPHVSIGL
Mb1099c|M.bovis_AF2122/97 GKLAAVRT-PTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGV
Rv1070c|M.tuberculosis_H37Rv GKLAAVRT-PTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGV
MLBr_02402|M.leprae_Br4923 GKLAAVRT-PMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
MAB_0836c|M.abscessus_ATCC_199 LLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGL
: * :.*: * . *.* : *: :: : *.* *.:. *:
Mvan_1984|M.vanbaalenii_PYR-1 VAAR-EMVRLARALPRSVALRMALMGKHERMSAERAYELGMITEVVEHDK
Mflv_4360|M.gilvum_PYR-GCK VAAR-EMVRLARALPRSVALRMALMGKHERMTAERAYELGMITEVVPHDT
MSMEG_2219|M.smegmatis_MC2_155 VAAR-EMVRLARALPRSVALRMALMGKHERMTVERAYELGLITEIVEHDN
MAV_1582|M.avium_104 VAGR-ELVRVSRVLPRSIALRMALMGKHERMSAQRAYELGLISEIVEHDR
TH_4071|M.thermoresistible__bu VSGR-EVVRLARVLPRSVALRMAIMGRHERMSAQRAYELGMVSEVVEHDR
MMAR_4023|M.marinum_M VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
MUL_3888|M.ulcerans_Agy99 VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
Mb1099c|M.bovis_AF2122/97 LPGMGGSQRLTRAIGKAKAMDLILTG--RTMDAAEAERSGLVSRVVPADD
Rv1070c|M.tuberculosis_H37Rv LPGMGGSQRLTRAIGKAKAMDLILTG--RTMDAAEAERSGLVSRVVPADD
MLBr_02402|M.leprae_Br4923 LPGMGGSQRLTRAIGKAKAMDLILTG--RTIDAAEAERSGLVSRVVLADD
MAB_0836c|M.abscessus_ATCC_199 VPGAGSMVRLKRQIPYTKAMEMILTG--EPLTAFEAYHFGLVGHVVPAGT
:.. *: * : : *: : : * . : . .* *:: .:* .
Mvan_1984|M.vanbaalenii_PYR-1 LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
Mflv_4360|M.gilvum_PYR-GCK LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
MSMEG_2219|M.smegmatis_MC2_155 LLQRAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLHDGEILAETFRERVV
MAV_1582|M.avium_104 LLERAHEIADIVNSNAPLAVRGTRLAILKGLNVPLHEAEILAETFRERVL
TH_4071|M.thermoresistible__bu LLERAHEIADIVTRNAPLAVRGTRLAIVKGLDLPLHEAEILAEAFRERNL
MMAR_4023|M.marinum_M LLARAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
MUL_3888|M.ulcerans_Agy99 LLERAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
Mb1099c|M.bovis_AF2122/97 LLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAF
Rv1070c|M.tuberculosis_H37Rv LLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAF
MLBr_02402|M.leprae_Br4923 LLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTF
MAB_0836c|M.abscessus_ATCC_199 ALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVI
* .*: * : . *.* :: *: : . :. : . .
Mvan_1984|M.vanbaalenii_PYR-1 RTEDAQEGPLAFVEKRAPDWQCR
Mflv_4360|M.gilvum_PYR-GCK RTEDAQEGPLAFVEKRAPNWQCR
MSMEG_2219|M.smegmatis_MC2_155 RTEDALEGPLAFVEKRKPVWKCR
MAV_1582|M.avium_104 RTEDAAEGPRAFVEKRQPNWQCR
TH_4071|M.thermoresistible__bu HTEDSLEGPRAFTEKREPRWQCR
MMAR_4023|M.marinum_M RTRDALEGPRAFAEKRDPDWQCQ
MUL_3888|M.ulcerans_Agy99 RTRDAFEGPRAFAEKRDPDWQCQ
Mb1099c|M.bovis_AF2122/97 ATEDQSEGMAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv ATEDQSEGMAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923 VTDDQSEGMAAFIEKRAPQFTHR
MAB_0836c|M.abscessus_ATCC_199 TSADAREGLAAFKEKREARFTGR
: * ** ** *** . : :