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VSSSPSYDTITYDVDGHKATITLNRPEALNALSPHMVSELRAAYDEAENDDDVWLMIVTGNGRAFCTGAD VKEIPEDGRVIYERPYLSTYDQWEAPQEGTPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATF FDPHVSIGLVAAREMVRLARALPRSVALRMALMGKHERMTAERAYELGMITEVVPHDTLLERAHEIADIV NSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVVRTEDAQEGPLAFVEKRAPNWQCR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4360 | - | - | 100% (271) | enoyl-CoA hydratase/isomerase |
| M. gilvum PYR-GCK | Mflv_4361 | - | 3e-40 | 41.56% (231) | enoyl-CoA hydratase/isomerase |
| M. gilvum PYR-GCK | Mflv_2117 | - | 2e-34 | 34.98% (263) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 6e-34 | 35.52% (259) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv3516 | echA19 | 3e-34 | 35.52% (259) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-30 | 30.71% (267) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 8e-37 | 35.74% (263) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4023 | echA11_1 | 1e-122 | 78.95% (266) | enoyl-CoA hydratase EchA11_1 |
| M. avium 104 | MAV_1582 | - | 1e-132 | 83.46% (266) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2219 | - | 1e-139 | 89.10% (266) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_4071 | - | 1e-130 | 82.16% (269) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_3888 | echA11_1 | 1e-121 | 78.95% (266) | enoyl-CoA hydratase EchA11_1 |
| M. vanbaalenii PYR-1 | Mvan_1984 | - | 1e-149 | 95.54% (269) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4360|M.gilvum_PYR-GCK -MSSSPSYDTITYDVDGHKATITLNRPEALNALSPHMVSELRAAYDEAEN
Mvan_1984|M.vanbaalenii_PYR-1 --MSSHSYDTIGYEVDGHKATITLNRPEALNALSPHMINELRAAYDEAEN
MSMEG_2219|M.smegmatis_MC2_155 ----MTTYDTIKYEVNGHTATITLNRPEALNALSPHMIGELRAAYAEAES
MAV_1582|M.avium_104 --MPVDSFDTIKYEVDGHTATITLNRPDALNALSPHMITELRAAYHEAEN
TH_4071|M.thermoresistible__bu --MSDTSYDTIKYEVDGHTATITLNRPDALNALSPHMITELRTAYDEAEN
MMAR_4023|M.marinum_M --MPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
MUL_3888|M.ulcerans_Agy99 MTMPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
Mb3545|M.bovis_AF2122/97 ----MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDN
Rv3516|M.tuberculosis_H37Rv ----MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDN
MAB_0836c|M.abscessus_ATCC_199 ----MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDH
MLBr_02402|M.leprae_Br4923 ----MKYDT-ILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDI
: :*:*** ***...*: : * . :
Mflv_4360|M.gilvum_PYR-GCK DDDVWLMIVTGNGRAFCTGADVKEIPEDGRVIYERPYLSTYDQWEAPQEG
Mvan_1984|M.vanbaalenii_PYR-1 DDDIWLMIVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
MSMEG_2219|M.smegmatis_MC2_155 DDDIWLTVVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
MAV_1582|M.avium_104 DDRVWLLVVTGTGRAFCSGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
TH_4071|M.thermoresistible__bu DDNVWLLVVTGTGRAFCSGADVKEIPEDGKVINERPYLSTYEQWEAPQEG
MMAR_4023|M.marinum_M NDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPYLATYEQWEAPQEG
MUL_3888|M.ulcerans_Agy99 DDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPDLATYEQWEAPQEG
Mb3545|M.bovis_AF2122/97 DPDIRCCILTGAGGYFCAGMDLKAATQ---KPPGDSFKDGSYDPSRIDA-
Rv3516|M.tuberculosis_H37Rv DPDIRCCILTGAGGYFCAGMDLKAATQ---KPPGDSFKDGSYGPSRIDA-
MAB_0836c|M.abscessus_ATCC_199 DDGIRAAILTGAGSAYCVGGDLSDGWM---VRDGSAP---PLDPATIGKG
MLBr_02402|M.leprae_Br4923 DPDVGAILITGSPKVFAAGADIKEMAS---LTFTDAF-----DADFFSA-
: : ::** :. * *:. .
Mflv_4360|M.gilvum_PYR-GCK TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
Mvan_1984|M.vanbaalenii_PYR-1 TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
MSMEG_2219|M.smegmatis_MC2_155 TPPFRTMAKPVIVAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
MAV_1582|M.avium_104 TPPFRTMAKPVLTAVNGICCGAGMDWVTTTDIVIASEQATFFDPHVSIGL
TH_4071|M.thermoresistible__bu TPPFRTMAKPVLAAINGICCGAGLDWVTTGDIVIASERATFFDPHVSIGL
MMAR_4023|M.marinum_M TPPFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASEAATFFDPHVSIGL
MUL_3888|M.ulcerans_Agy99 TPLFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASETATFFDPHVSIGL
Mb3545|M.bovis_AF2122/97 LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSL
Rv3516|M.tuberculosis_H37Rv LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSL
MAB_0836c|M.abscessus_ATCC_199 LLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGL
MLBr_02402|M.leprae_Br4923 WGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
: .*::.*: * . ..* : *: :: : *.* .. . .:
Mflv_4360|M.gilvum_PYR-GCK VAAR-EMVRLARALPRSVALRMALMGKHERMTAERAYELGMITEVVPHDT
Mvan_1984|M.vanbaalenii_PYR-1 VAAR-EMVRLARALPRSVALRMALMGKHERMSAERAYELGMITEVVEHDK
MSMEG_2219|M.smegmatis_MC2_155 VAAR-EMVRLARALPRSVALRMALMGKHERMTVERAYELGLITEIVEHDN
MAV_1582|M.avium_104 VAGR-ELVRVSRVLPRSIALRMALMGKHERMSAQRAYELGLISEIVEHDR
TH_4071|M.thermoresistible__bu VSGR-EVVRLARVLPRSVALRMAIMGRHERMSAQRAYELGMVSEVVEHDR
MMAR_4023|M.marinum_M VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
MUL_3888|M.ulcerans_Agy99 VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
Mb3545|M.bovis_AF2122/97 YPMGGSAVRLVRQIPYTLACDLLLTG--RHITAAEAKEMGLIGHVVPDGQ
Rv3516|M.tuberculosis_H37Rv YPMGGSAVRLVRQIPYTLACDLLLTG--RHITAAEAKEMGLIGHVVPDGQ
MAB_0836c|M.abscessus_ATCC_199 VPGAGSMVRLKRQIPYTKAMEMILTG--EPLTAFEAYHFGLVGHVVPAGT
MLBr_02402|M.leprae_Br4923 LPGMGGSQRLTRAIGKAKAMDLILTG--RTIDAAEAERSGLVSRVVLADD
. *: * : : * : : * . : . .* *:: .:* .
Mflv_4360|M.gilvum_PYR-GCK LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
Mvan_1984|M.vanbaalenii_PYR-1 LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
MSMEG_2219|M.smegmatis_MC2_155 LLQRAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLHDGEILAETFRERVV
MAV_1582|M.avium_104 LLERAHEIADIVNSNAPLAVRGTRLAILKGLNVPLHEAEILAETFRERVL
TH_4071|M.thermoresistible__bu LLERAHEIADIVTRNAPLAVRGTRLAIVKGLDLPLHEAEILAEAFRERNL
MMAR_4023|M.marinum_M LLARAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
MUL_3888|M.ulcerans_Agy99 LLERAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
Mb3545|M.bovis_AF2122/97 ALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVF
Rv3516|M.tuberculosis_H37Rv ALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVF
MAB_0836c|M.abscessus_ATCC_199 ALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVI
MLBr_02402|M.leprae_Br4923 LLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTF
* .* :* : . *.: :: . . :. : .
Mflv_4360|M.gilvum_PYR-GCK RTEDAQEGPLAFVEKRAPNWQCR
Mvan_1984|M.vanbaalenii_PYR-1 RTEDAQEGPLAFVEKRAPDWQCR
MSMEG_2219|M.smegmatis_MC2_155 RTEDALEGPLAFVEKRKPVWKCR
MAV_1582|M.avium_104 RTEDAAEGPRAFVEKRQPNWQCR
TH_4071|M.thermoresistible__bu HTEDSLEGPRAFTEKREPRWQCR
MMAR_4023|M.marinum_M RTRDALEGPRAFAEKRDPDWQCQ
MUL_3888|M.ulcerans_Agy99 RTRDAFEGPRAFAEKRDPDWQCQ
Mb3545|M.bovis_AF2122/97 LSDDAKEGPRAFAEKRAPNFQNR
Rv3516|M.tuberculosis_H37Rv LSDDAKEGPRAFAEKRAPNFQNR
MAB_0836c|M.abscessus_ATCC_199 TSADAREGLAAFKEKREARFTGR
MLBr_02402|M.leprae_Br4923 VTDDQSEGMAAFIEKRAPQFTHR
: * ** ** *** . : :