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MPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEGNDRVWLTIVTGTGRAFCTGADV KAIPGDGKVIYERPYLATYEQWEAPQEGTPPFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASEAATFF DPHVSIGLVAGRELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDRLLARAHEIADMVN RNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVLRTRDALEGPRAFAEKRDPDWQCQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4023 | echA11_1 | - | 100% (270) | enoyl-CoA hydratase EchA11_1 |
| M. marinum M | MMAR_4024 | echA16_1 | 2e-34 | 40.83% (218) | enoyl-CoA hydratase EchA16_1 |
| M. marinum M | MMAR_4317 | echA1_1 | 2e-30 | 34.85% (264) | enoyl-CoA hydratase, EchA1_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 3e-30 | 34.73% (262) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4360 | - | 1e-122 | 78.95% (266) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv3516 | echA19 | 3e-30 | 34.73% (262) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_00120 | echA1 | 5e-25 | 30.15% (272) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 3e-35 | 36.22% (254) | putative enoyl-CoA hydratase/isomerase |
| M. avium 104 | MAV_1582 | - | 1e-134 | 84.07% (270) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2219 | - | 1e-124 | 80.00% (265) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_4071 | - | 1e-129 | 81.11% (270) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_3888 | echA11_1 | 1e-152 | 97.78% (270) | enoyl-CoA hydratase EchA11_1 |
| M. vanbaalenii PYR-1 | Mvan_1984 | - | 1e-126 | 81.20% (266) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3545|M.bovis_AF2122/97 -----MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVD
Rv3516|M.tuberculosis_H37Rv -----MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVD
MAB_0836c|M.abscessus_ATCC_199 -----MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEID
MMAR_4023|M.marinum_M ---MPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAE
MUL_3888|M.ulcerans_Agy99 -MTMPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAE
MAV_1582|M.avium_104 ---MPVDSFDTIKYEVDGHTATITLNRPDALNALSPHMITELRAAYHEAE
TH_4071|M.thermoresistible__bu ---MSDTSYDTIKYEVDGHTATITLNRPDALNALSPHMITELRTAYDEAE
Mflv_4360|M.gilvum_PYR-GCK --MSSSPSYDTITYDVDGHKATITLNRPEALNALSPHMVSELRAAYDEAE
Mvan_1984|M.vanbaalenii_PYR-1 ---MSSHSYDTIGYEVDGHKATITLNRPEALNALSPHMINELRAAYDEAE
MSMEG_2219|M.smegmatis_MC2_155 -----MTTYDTIKYEVNGHTATITLNRPEALNALSPHMIGELRAAYAEAE
MLBr_00120|M.leprae_Br4923 MGSDINRAYESVAVEIKDRVAQVTLIGPGKGNAMGPAFWSEMPEVFAELD
: : . :*: * **:.. : : .: . :
Mb3545|M.bovis_AF2122/97 NDPDIRCCILTGAGGYFCAGMDLKAATQ--------KPPGDSFKDGSYDP
Rv3516|M.tuberculosis_H37Rv NDPDIRCCILTGAGGYFCAGMDLKAATQ--------KPPGDSFKDGSYGP
MAB_0836c|M.abscessus_ATCC_199 HDDGIRAAILTGAGSAYCVGGDLSDGWM--------VRDGSAP---PLDP
MMAR_4023|M.marinum_M GNDRVWLTIVTGTGRAFCTGADVKAIPGDGK-----VIYERPYLATYEQW
MUL_3888|M.ulcerans_Agy99 GDDRVWLTIVTGTGRAFCTGADVKAIPGDGK-----VIYERPDLATYEQW
MAV_1582|M.avium_104 NDDRVWLLVVTGTGRAFCSGADVKEIPEDGK-----VIYERPYLSTYDQW
TH_4071|M.thermoresistible__bu NDDNVWLLVVTGTGRAFCSGADVKEIPEDGK-----VINERPYLSTYEQW
Mflv_4360|M.gilvum_PYR-GCK NDDDVWLMIVTGNGRAFCTGADVKEIPEDGR-----VIYERPYLSTYDQW
Mvan_1984|M.vanbaalenii_PYR-1 NDDDIWLMIVTGTGRAFCTGADVKEIPEDGK-----VIYERPYLSTYDQW
MSMEG_2219|M.smegmatis_MC2_155 SDDDIWLTVVTGTGRAFCTGADVKEIPEDGK-----VIYERPYLSTYDQW
MLBr_00120|M.leprae_Br4923 TNREVRAVVITGSGKDFSYGLDVPAMGGKFVPLLTDGALARPRTDFHAEV
: : ::** * :. * *: .
Mb3545|M.bovis_AF2122/97 SRIDA-LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGIS
Rv3516|M.tuberculosis_H37Rv SRIDA-LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGIS
MAB_0836c|M.abscessus_ATCC_199 ATIGKGLLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLP
MMAR_4023|M.marinum_M EAPQEGTPPFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASEAATFFDP
MUL_3888|M.ulcerans_Agy99 EAPQEGTPLFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASETATFFDP
MAV_1582|M.avium_104 EAPQEGTPPFRTMAKPVLTAVNGICCGAGMDWVTTTDIVIASEQATFFDP
TH_4071|M.thermoresistible__bu EAPQEGTPPFRTMAKPVLAAINGICCGAGLDWVTTGDIVIASERATFFDP
Mflv_4360|M.gilvum_PYR-GCK EAPQEGTPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDP
Mvan_1984|M.vanbaalenii_PYR-1 EAPQEGTPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDP
MSMEG_2219|M.smegmatis_MC2_155 EAPQEGTPPFRTMAKPVIVAINGICCGAGLDWVTTGDIVIASDKATFFDP
MLBr_00120|M.leprae_Br4923 LRMQKAINAVADCRTPTIAAVHGWCIGGALDLISAVDIRYASADAKFSMR
.* :.*:.* . ... : : ** :. *.*
Mb3545|M.bovis_AF2122/97 EAKWSLYPMGGSAVRLVRQIPYTLACDLLLTG--RHITAAEAKEMGLIGH
Rv3516|M.tuberculosis_H37Rv EAKWSLYPMGGSAVRLVRQIPYTLACDLLLTG--RHITAAEAKEMGLIGH
MAB_0836c|M.abscessus_ATCC_199 EVQRGLVPGAGSMVRLKRQIPYTKAMEMILTG--EPLTAFEAYHFGLVGH
MMAR_4023|M.marinum_M HVSIGLVAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISE
MUL_3888|M.ulcerans_Agy99 HVSIGLVAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISE
MAV_1582|M.avium_104 HVSIGLVAGR-ELVRVSRVLPRSIALRMALMGKHERMSAQRAYELGLISE
TH_4071|M.thermoresistible__bu HVSIGLVSGR-EVVRLARVLPRSVALRMAIMGRHERMSAQRAYELGMVSE
Mflv_4360|M.gilvum_PYR-GCK HVSIGLVAAR-EMVRLARALPRSVALRMALMGKHERMTAERAYELGMITE
Mvan_1984|M.vanbaalenii_PYR-1 HVSIGLVAAR-EMVRLARALPRSVALRMALMGKHERMSAERAYELGMITE
MSMEG_2219|M.smegmatis_MC2_155 HVSIGLVAAR-EMVRLARALPRSVALRMALMGKHERMTVERAYELGLITE
MLBr_00120|M.leprae_Br4923 EVKLAIVADMGSLARLPLILSDGHLRELALTG--KDIDATRAEKIGLVND
... .: . . .*: :. : : * . : . .* .:*:: .
Mb3545|M.bovis_AF2122/97 VVP-DGQALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDT
Rv3516|M.tuberculosis_H37Rv VVP-DGQALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDT
MAB_0836c|M.abscessus_ATCC_199 VVP-AGTALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEA
MMAR_4023|M.marinum_M VVE-HDRLLARAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAE
MUL_3888|M.ulcerans_Agy99 VVE-HDRLLERAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAE
MAV_1582|M.avium_104 IVE-HDRLLERAHEIADIVNSNAPLAVRGTRLAILKGLNVPLHEAEILAE
TH_4071|M.thermoresistible__bu VVE-HDRLLERAHEIADIVTRNAPLAVRGTRLAIVKGLDLPLHEAEILAE
Mflv_4360|M.gilvum_PYR-GCK VVP-HDTLLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAE
Mvan_1984|M.vanbaalenii_PYR-1 VVE-HDKLLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAE
MSMEG_2219|M.smegmatis_MC2_155 IVE-HDNLLQRAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLHDGEILAE
MLBr_00120|M.leprae_Br4923 VYDNADKTLAAAHATAAEIAANPPLAVYGVKDVLYQQRTSAISESLRYVA
: . * * * : * **** : . . :.
Mb3545|M.bovis_AF2122/97 QIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
Rv3516|M.tuberculosis_H37Rv QIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
MAB_0836c|M.abscessus_ATCC_199 RLTRPVITSADAREGLAAFKEKREARFTGR
MMAR_4023|M.marinum_M AFRERVLRTRDALEGPRAFAEKRDPDWQCQ
MUL_3888|M.ulcerans_Agy99 AFRERVLRTRDAFEGPRAFAEKRDPDWQCQ
MAV_1582|M.avium_104 TFRERVLRTEDAAEGPRAFVEKRQPNWQCR
TH_4071|M.thermoresistible__bu AFRERNLHTEDSLEGPRAFTEKREPRWQCR
Mflv_4360|M.gilvum_PYR-GCK TFRERVVRTEDAQEGPLAFVEKRAPNWQCR
Mvan_1984|M.vanbaalenii_PYR-1 TFRERVVRTEDAQEGPLAFVEKRAPDWQCR
MSMEG_2219|M.smegmatis_MC2_155 TFRERVVRTEDALEGPLAFVEKRKPVWKCR
MLBr_00120|M.leprae_Br4923 AWNAAFLPSKDLTEGISATFAKRAPQFIGE
. : * ** * ** . : .