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MTMPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEGDDRVWLTIVTGTGRAFCTGA DVKAIPGDGKVIYERPDLATYEQWEAPQEGTPLFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASETAT FFDPHVSIGLVAGRELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDRLLERAHEIADM VNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVLRTRDAFEGPRAFAEKRDPDWQCQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3888 | echA11_1 | - | 100% (272) | enoyl-CoA hydratase EchA11_1 |
| M. ulcerans Agy99 | MUL_3889 | echA16_1 | 3e-34 | 39.63% (217) | enoyl-CoA hydratase EchA16_1 |
| M. ulcerans Agy99 | MUL_0972 | echA1_1 | 3e-30 | 35.00% (260) | enoyl-CoA hydratase, EchA1_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 1e-30 | 34.73% (262) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4360 | - | 1e-121 | 78.95% (266) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv3516 | echA19 | 2e-30 | 34.10% (261) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-25 | 29.66% (263) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 3e-37 | 37.01% (254) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4023 | echA11_1 | 1e-151 | 97.78% (270) | enoyl-CoA hydratase EchA11_1 |
| M. avium 104 | MAV_1582 | - | 1e-133 | 84.07% (270) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2219 | - | 1e-123 | 79.25% (265) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_4071 | - | 1e-127 | 80.74% (270) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1984 | - | 1e-125 | 81.20% (266) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3888|M.ulcerans_Agy99 MTMPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
MMAR_4023|M.marinum_M --MPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
MAV_1582|M.avium_104 --MPVDSFDTIKYEVDGHTATITLNRPDALNALSPHMITELRAAYHEAEN
TH_4071|M.thermoresistible__bu --MSDTSYDTIKYEVDGHTATITLNRPDALNALSPHMITELRTAYDEAEN
Mflv_4360|M.gilvum_PYR-GCK -MSSSPSYDTITYDVDGHKATITLNRPEALNALSPHMVSELRAAYDEAEN
Mvan_1984|M.vanbaalenii_PYR-1 --MSSHSYDTIGYEVDGHKATITLNRPEALNALSPHMINELRAAYDEAEN
MSMEG_2219|M.smegmatis_MC2_155 ----MTTYDTIKYEVNGHTATITLNRPEALNALSPHMIGELRAAYAEAES
Mb3545|M.bovis_AF2122/97 ----MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDN
Rv3516|M.tuberculosis_H37Rv ----MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDN
MAB_0836c|M.abscessus_ATCC_199 ----MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDH
MLBr_02402|M.leprae_Br4923 ----MKYDT-ILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDI
: :*:*** ***...*: : * . :
MUL_3888|M.ulcerans_Agy99 DDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPDLATYEQWEAPQEG
MMAR_4023|M.marinum_M NDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPYLATYEQWEAPQEG
MAV_1582|M.avium_104 DDRVWLLVVTGTGRAFCSGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
TH_4071|M.thermoresistible__bu DDNVWLLVVTGTGRAFCSGADVKEIPEDGKVINERPYLSTYEQWEAPQEG
Mflv_4360|M.gilvum_PYR-GCK DDDVWLMIVTGNGRAFCTGADVKEIPEDGRVIYERPYLSTYDQWEAPQEG
Mvan_1984|M.vanbaalenii_PYR-1 DDDIWLMIVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
MSMEG_2219|M.smegmatis_MC2_155 DDDIWLTVVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
Mb3545|M.bovis_AF2122/97 DPDIRCCILTGAGGYFCAGMDLKAATQ---KPPGDSFKDGSYDPSRIDA-
Rv3516|M.tuberculosis_H37Rv DPDIRCCILTGAGGYFCAGMDLKAATQ---KPPGDSFKDGSYGPSRIDA-
MAB_0836c|M.abscessus_ATCC_199 DDGIRAAILTGAGSAYCVGGDLSDGWM---VRDGSAP---PLDPATIGKG
MLBr_02402|M.leprae_Br4923 DPDVGAILITGSPKVFAAGADIKEMAS---LTFTDAF-----DADFFSA-
: : ::** :. * *:. .
MUL_3888|M.ulcerans_Agy99 TPLFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASETATFFDPHVSIGL
MMAR_4023|M.marinum_M TPPFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASEAATFFDPHVSIGL
MAV_1582|M.avium_104 TPPFRTMAKPVLTAVNGICCGAGMDWVTTTDIVIASEQATFFDPHVSIGL
TH_4071|M.thermoresistible__bu TPPFRTMAKPVLAAINGICCGAGLDWVTTGDIVIASERATFFDPHVSIGL
Mflv_4360|M.gilvum_PYR-GCK TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
Mvan_1984|M.vanbaalenii_PYR-1 TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
MSMEG_2219|M.smegmatis_MC2_155 TPPFRTMAKPVIVAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
Mb3545|M.bovis_AF2122/97 LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSL
Rv3516|M.tuberculosis_H37Rv LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSL
MAB_0836c|M.abscessus_ATCC_199 LLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGL
MLBr_02402|M.leprae_Br4923 WGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
: .*::.*: * . ..* : *: :: : *.* .. . .:
MUL_3888|M.ulcerans_Agy99 VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
MMAR_4023|M.marinum_M VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
MAV_1582|M.avium_104 VAGR-ELVRVSRVLPRSIALRMALMGKHERMSAQRAYELGLISEIVEHDR
TH_4071|M.thermoresistible__bu VSGR-EVVRLARVLPRSVALRMAIMGRHERMSAQRAYELGMVSEVVEHDR
Mflv_4360|M.gilvum_PYR-GCK VAAR-EMVRLARALPRSVALRMALMGKHERMTAERAYELGMITEVVPHDT
Mvan_1984|M.vanbaalenii_PYR-1 VAAR-EMVRLARALPRSVALRMALMGKHERMSAERAYELGMITEVVEHDK
MSMEG_2219|M.smegmatis_MC2_155 VAAR-EMVRLARALPRSVALRMALMGKHERMTVERAYELGLITEIVEHDN
Mb3545|M.bovis_AF2122/97 YPMGGSAVRLVRQIPYTLACDLLLTG--RHITAAEAKEMGLIGHVVPDGQ
Rv3516|M.tuberculosis_H37Rv YPMGGSAVRLVRQIPYTLACDLLLTG--RHITAAEAKEMGLIGHVVPDGQ
MAB_0836c|M.abscessus_ATCC_199 VPGAGSMVRLKRQIPYTKAMEMILTG--EPLTAFEAYHFGLVGHVVPAGT
MLBr_02402|M.leprae_Br4923 LPGMGGSQRLTRAIGKAKAMDLILTG--RTIDAAEAERSGLVSRVVLADD
. *: * : : * : : * . : . .* *:: .:* .
MUL_3888|M.ulcerans_Agy99 LLERAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
MMAR_4023|M.marinum_M LLARAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
MAV_1582|M.avium_104 LLERAHEIADIVNSNAPLAVRGTRLAILKGLNVPLHEAEILAETFRERVL
TH_4071|M.thermoresistible__bu LLERAHEIADIVTRNAPLAVRGTRLAIVKGLDLPLHEAEILAEAFRERNL
Mflv_4360|M.gilvum_PYR-GCK LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
Mvan_1984|M.vanbaalenii_PYR-1 LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
MSMEG_2219|M.smegmatis_MC2_155 LLQRAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLHDGEILAETFRERVV
Mb3545|M.bovis_AF2122/97 ALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVF
Rv3516|M.tuberculosis_H37Rv ALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVF
MAB_0836c|M.abscessus_ATCC_199 ALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVI
MLBr_02402|M.leprae_Br4923 LLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTF
* .* :* : . *.: :: . . :. : .
MUL_3888|M.ulcerans_Agy99 RTRDAFEGPRAFAEKRDPDWQCQ
MMAR_4023|M.marinum_M RTRDALEGPRAFAEKRDPDWQCQ
MAV_1582|M.avium_104 RTEDAAEGPRAFVEKRQPNWQCR
TH_4071|M.thermoresistible__bu HTEDSLEGPRAFTEKREPRWQCR
Mflv_4360|M.gilvum_PYR-GCK RTEDAQEGPLAFVEKRAPNWQCR
Mvan_1984|M.vanbaalenii_PYR-1 RTEDAQEGPLAFVEKRAPDWQCR
MSMEG_2219|M.smegmatis_MC2_155 RTEDALEGPLAFVEKRKPVWKCR
Mb3545|M.bovis_AF2122/97 LSDDAKEGPRAFAEKRAPNFQNR
Rv3516|M.tuberculosis_H37Rv LSDDAKEGPRAFAEKRAPNFQNR
MAB_0836c|M.abscessus_ATCC_199 TSADAREGLAAFKEKREARFTGR
MLBr_02402|M.leprae_Br4923 VTDDQSEGMAAFIEKRAPQFTHR
: * ** ** *** . : :