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SLVTYELDDHVATITLNRPDARNAINGALRRDLNAAWNRFRDDEDAWVGILTANGDVFCAGGDLKDGEGS VGTFGGTFWEKPTINSFESGMELFKPTIAAVHGPCIGYGLTGVLFCDFVIASTEASFAYPEVSLGVPTIV GAIRLPERVRWADAMELLLTGRPITAERAKEIGLVWRLVEPDRLQSEAQSWARTLTEAAPLAQRATKEVA SRTANMGWIESVRFGETMRKVAGATEDVAEGIAAWREKRTPKWRAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2610 | - | - | 100% (257) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1984 | - | 4e-40 | 34.96% (266) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_0344 | - | 5e-36 | 38.28% (256) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 2e-35 | 37.21% (258) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4360 | - | 8e-41 | 35.34% (266) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 2e-35 | 37.21% (258) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 7e-31 | 35.22% (247) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2058 | - | 5e-36 | 38.34% (253) | enoyl-CoA dehydratase/isomerase |
| M. marinum M | MMAR_0465 | echA1 | 3e-35 | 39.15% (258) | enoyl-CoA hydratase EchA1 |
| M. avium 104 | MAV_2740 | - | 1e-136 | 89.88% (257) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_0335 | - | 4e-38 | 39.53% (258) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_3674 | - | 1e-132 | 85.99% (257) | PUTATIVE enoyl-CoA hydratase/isomerase family protein |
| M. ulcerans Agy99 | MUL_3888 | echA11_1 | 2e-35 | 35.34% (266) | enoyl-CoA hydratase EchA11_1 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2058|M.abscessus_ATCC_1997 MAEQP------IRYEVVDSVAWLTINRPEARNALNNAVRTGLIDAVLRFN
MSMEG_0335|M.smegmatis_MC2_155 ---MS------VDYEVRNGVAWLTINRPEARNSLNKAVRDGLFDGVRRFN
MMAR_0465|M.marinum_M MSELNGDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAMDRLD
Mb1099c|M.bovis_AF2122/97 MTYET------ILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
Rv1070c|M.tuberculosis_H37Rv MTYET------ILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
MLBr_02402|M.leprae_Br4923 MKYDT------ILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELD
Mvan_2610|M.vanbaalenii_PYR-1 --------MSLVTYELDDHVATITLNRPDARNAINGALRRDLNAAWNRFR
MAV_2740|M.avium_104 --------MSLVTYELHDHVATITLNRPEARNAINGALRQDLNAAWDRFR
TH_3674|M.thermoresistible__bu -----VQTMSLVTYEQRDHIATITLNRPEARNAINGAMRQDLNAAWNRFR
Mflv_4360|M.gilvum_PYR-GCK -MSSS-PSYDTITYDVDGHKATITLNRPEALNALSPHMVSELRAAYDEAE
MUL_3888|M.ulcerans_Agy99 -MTMPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAE
: : :*:***.* *::. : : . .
MAB_2058|M.abscessus_ATCC_1997 DDDAAKVLVLTGVGDKAFCAGGDLK------EMAQNAL-KVPPKDFAPQ-
MSMEG_0335|M.smegmatis_MC2_155 NDAQAKVLVLTGAGDKAFCAGGDLK------EMSDDQL-TVPPIDFVPQ-
MMAR_0465|M.marinum_M ADAGLSVGILTGAGG-SFCAGMDLK------AFARGEN-VVVEGRGLGF-
Mb1099c|M.bovis_AF2122/97 DDPDIGAIIITGSAK-AFAAGADIK------EMADLTFADAFTADFFAT-
Rv1070c|M.tuberculosis_H37Rv DDPDIGAIIITGSAK-AFAAGADIK------EMADLTFADAFTADFFAT-
MLBr_02402|M.leprae_Br4923 IDPDVGAILITGSPK-VFAAGADIK------EMASLTFTDAFDADFFSA-
Mvan_2610|M.vanbaalenii_PYR-1 DDEDAWVGILTANGD-VFCAGGDLKDGEGSVGTFGGTFWEKPTINSFES-
MAV_2740|M.avium_104 DDLDAWVGILTANGD-VFCAGGDLKDGEGSVGTFGGTFWEKPTINSFES-
TH_3674|M.thermoresistible__bu DDEDAWVGILTANGE-VFCAGADLKDSEGAVGTFGGTFWEKPTINSFES-
Mflv_4360|M.gilvum_PYR-GCK NDDDVWLMIVTGNGR-AFCTGADVK----EIPEDGRVIYERPYLSTYDQW
MUL_3888|M.ulcerans_Agy99 GDDRVWLTIVTGTGR-AFCTGADVK----AIPGDGKVIYERPDLATYEQW
* ::*. *.:* *:*
MAB_2058|M.abscessus_ATCC_1997 ------FGRNIDVAKPTIAAVNGVAFAGGFLLAQQCDLVVAAEHATFAVS
MSMEG_0335|M.smegmatis_MC2_155 ------FGRNITVDKPTIAAVNGVAFAGGFLLAQTCDLCVASTTAKFAIT
MMAR_0465|M.marinum_M ------TER--PPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIP
Mb1099c|M.bovis_AF2122/97 ------WGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQP
Rv1070c|M.tuberculosis_H37Rv ------WGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQP
MLBr_02402|M.leprae_Br4923 ------WGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQP
Mvan_2610|M.vanbaalenii_PYR-1 -----GMELF----KPTIAAVHGPCIGYGLTGVLFCDFVIASTEASFAYP
MAV_2740|M.avium_104 -----GMELF----KPTIAAVHGPCIGYGLTGVLFCDFVIASTEATFCYP
TH_3674|M.thermoresistible__bu -----GMELF----KPTIAAVNGPCVGYGLTGVLFCDFVIASTTATFSFP
Mflv_4360|M.gilvum_PYR-GCK EAPQEGTPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDP
MUL_3888|M.ulcerans_Agy99 EAPQEGTPLFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASETATFFDP
.* ::*: * . . * . *. :*: : * .
MAB_2058|M.abscessus_ATCC_1997 EVKVG--RGSPWATPLSWLVPPRVAMQILLTGD--PITAARAHQVGLVNE
MSMEG_0335|M.smegmatis_MC2_155 EAKVG--RGSPWAAPLPLMIPRRIAMELVLTGA--PISAARAHEIGFVNR
MMAR_0465|M.marinum_M EVKRGLVAGGGGLLRLPERIPYAIAMELALTGD--NLSAERAHALGMVNV
Mb1099c|M.bovis_AF2122/97 EIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGR--TMDAAEAERSGLVSR
Rv1070c|M.tuberculosis_H37Rv EIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGR--TMDAAEAERSGLVSR
MLBr_02402|M.leprae_Br4923 EIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGR--TIDAAEAERSGLVSR
Mvan_2610|M.vanbaalenii_PYR-1 EVSLG-VPTIVGAIRLPERVRWADAMELLLTGR--PITAERAKEIGLVWR
MAV_2740|M.avium_104 EVAIG-VPTIVGAIRLPRRVGWANAMELLLTGK--PMSAERAKEIGLVWK
TH_3674|M.thermoresistible__bu EVRIG-VPTIVGAIRLPQRVRWADAMELLLTGK--PITAQRAEEIGLVWR
Mflv_4360|M.gilvum_PYR-GCK HVSIG-LVAAREMVRLARALPRSVALRMALMGKHERMTAERAYELGMITE
MUL_3888|M.ulcerans_Agy99 HVSIG-LVAGRELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISE
. * *. : *: : * * : * .* *::
MAB_2058|M.abscessus_ATCC_1997 VVPADQLRERTQQLALSIAANAPLSVLASKRTVYLSAQHHLAAAYDLADE
MSMEG_0335|M.smegmatis_MC2_155 LAEPADLHAVAQKLAEQIAANAPLSVAAGKRTATLTAEHPLSEAFDIAES
MMAR_0465|M.marinum_M LAEPGAALDAAIALAEKITANGPLAVAATKRIITESRGWSLDTRFAQQMK
Mb1099c|M.bovis_AF2122/97 VVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERR
Rv1070c|M.tuberculosis_H37Rv VVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERR
MLBr_02402|M.leprae_Br4923 VVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERR
Mvan_2610|M.vanbaalenii_PYR-1 LVEPDRLQSEAQSWARTLTEAAPLAQRATKEVASRTANMGWIESVRFGET
MAV_2740|M.avium_104 LVEPDRLQAEARAWARTLTEAAPLAQRATKEVAWRTADMGWIESVRFGET
TH_3674|M.thermoresistible__bu LVPPDELQEQALAWARTLTEAAPLAQRATKEVAWRSADMGWIEAVRFGET
Mflv_4360|M.gilvum_PYR-GCK VVPHDTLLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAET
MUL_3888|M.ulcerans_Agy99 VVEHDRLLERAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEA
:. : * : . : :
MAB_2058|M.abscessus_ATCC_1997 IWEPVYLSDDAQEGPAAFREKRAPQWKGH
MSMEG_0335|M.smegmatis_MC2_155 IWEPVYLSGDAQEGMAAFKEKRSPVWKGR
MMAR_0465|M.marinum_M ILFPIFTSNDAKEGAIAFAEKRPPRWTGT
Mb1099c|M.bovis_AF2122/97 LFHSAFATEDQSEGMAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv LFHSAFATEDQSEGMAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923 LFHSTFVTDDQSEGMAAFIEKRAPQFTHR
Mvan_2610|M.vanbaalenii_PYR-1 MRKVAGATEDVAEGIAAWREKRTPKWRAR
MAV_2740|M.avium_104 MRKVAGATEDVAEGIRAWTEKRKPQWRGR
TH_3674|M.thermoresistible__bu MRKVAGATEDVAEGIRAWQEKRTPQWRGR
Mflv_4360|M.gilvum_PYR-GCK FRERVVRTEDAQEGPLAFVEKRAPNWQCR
MUL_3888|M.ulcerans_Agy99 FRERVLRTRDAFEGPRAFAEKRDPDWQCQ
: : * ** *: *** * :