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M. smegmatis MC2 155 MSMEG_2219 (-)

annotation: enoyl-CoA hydratase/isomerase family protein
coordinates: 2300197 - 2301003
length: 268

TTYDTIKYEVNGHTATITLNRPEALNALSPHMIGELRAAYAEAESDDDIWLTVVTGTGRAFCTGADVKEI
PEDGKVIYERPYLSTYDQWEAPQEGTPPFRTMAKPVIVAINGICCGAGLDWVTTGDIVIASDKATFFDPH
VSIGLVAAREMVRLARALPRSVALRMALMGKHERMTVERAYELGLITEIVEHDNLLQRAHEIADIVNSNA
PLAVRGTRLAIHKTLDLPLHDGEILAETFRERVVRTEDALEGPLAFVEKRKPVWKCR*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_2219 - - 100% (268) enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155 MSMEG_2218 - 1e-37 39.06% (233) enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155 MSMEG_5198 - 5e-34 34.32% (271) carnitinyl-CoA dehydratase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1099c echA8 6e-31 31.18% (263) enoyl-CoA hydratase
M. gilvum PYR-GCK Mflv_4360 - 1e-139 89.10% (266) enoyl-CoA hydratase/isomerase
M. tuberculosis H37Rv Rv1070c echA8 6e-31 31.18% (263) enoyl-CoA hydratase
M. leprae Br4923 MLBr_02402 - 8e-28 29.01% (262) enoyl-CoA hydratase
M. abscessus ATCC 19977 MAB_0836c - 3e-34 33.83% (266) putative enoyl-CoA hydratase/isomerase
M. marinum M MMAR_4023 echA11_1 1e-124 80.00% (265) enoyl-CoA hydratase EchA11_1
M. avium 104 MAV_1582 - 1e-132 84.21% (266) enoyl-CoA hydratase/isomerase family protein
M. thermoresistible (build 8) TH_4071 - 1e-130 82.02% (267) PUTATIVE Enoyl-CoA hydratase/isomerase
M. ulcerans Agy99 MUL_3888 echA11_1 1e-123 79.25% (265) enoyl-CoA hydratase EchA11_1
M. vanbaalenii PYR-1 Mvan_1984 - 1e-140 90.98% (266) enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4360|M.gilvum_PYR-GCK          -MSSSPSYDTITYDVDGHKATITLNRPEALNALSPHMVSELRAAYDEAEN
Mvan_1984|M.vanbaalenii_PYR-1       --MSSHSYDTIGYEVDGHKATITLNRPEALNALSPHMINELRAAYDEAEN
MSMEG_2219|M.smegmatis_MC2_155      ----MTTYDTIKYEVNGHTATITLNRPEALNALSPHMIGELRAAYAEAES
MAV_1582|M.avium_104                --MPVDSFDTIKYEVDGHTATITLNRPDALNALSPHMITELRAAYHEAEN
TH_4071|M.thermoresistible__bu      --MSDTSYDTIKYEVDGHTATITLNRPDALNALSPHMITELRTAYDEAEN
MMAR_4023|M.marinum_M               --MPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
MUL_3888|M.ulcerans_Agy99           MTMPGDAFDTIGYELDGHTATITLNRPHALNALSPHMITELRAAYAEAEG
Mb1099c|M.bovis_AF2122/97           -----MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDD
Rv1070c|M.tuberculosis_H37Rv        -----MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDD
MLBr_02402|M.leprae_Br4923          -----MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDI
MAB_0836c|M.abscessus_ATCC_199      ----MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDH
                                              :  :       :*:***.  ***..::: :.  *  * : 

Mflv_4360|M.gilvum_PYR-GCK          DDDVWLMIVTGNGRAFCTGADVKEIPEDGRVIYERPYLSTYDQWEAPQEG
Mvan_1984|M.vanbaalenii_PYR-1       DDDIWLMIVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
MSMEG_2219|M.smegmatis_MC2_155      DDDIWLTVVTGTGRAFCTGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
MAV_1582|M.avium_104                DDRVWLLVVTGTGRAFCSGADVKEIPEDGKVIYERPYLSTYDQWEAPQEG
TH_4071|M.thermoresistible__bu      DDNVWLLVVTGTGRAFCSGADVKEIPEDGKVINERPYLSTYEQWEAPQEG
MMAR_4023|M.marinum_M               NDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPYLATYEQWEAPQEG
MUL_3888|M.ulcerans_Agy99           DDRVWLTIVTGTGRAFCTGADVKAIPGDGKVIYERPDLATYEQWEAPQEG
Mb1099c|M.bovis_AF2122/97           DPDIGAIIITGSAKAFAAGADIKE--------MADLTFADAFTADFFATW
Rv1070c|M.tuberculosis_H37Rv        DPDIGAIIITGSAKAFAAGADIKE--------MADLTFADAFTADFFATW
MLBr_02402|M.leprae_Br4923          DPDVGAILITGSPKVFAAGADIKE--------MASLTFTDAFDADFFSAW
MAB_0836c|M.abscessus_ATCC_199      DDGIRAAILTGAGSAYCVGGDLSDG------WMVRDGSAPPLDPATIGKG
                                    :  :   ::**   .:. *.*:.               :           

Mflv_4360|M.gilvum_PYR-GCK          TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
Mvan_1984|M.vanbaalenii_PYR-1       TPPFRRMAKPVLAAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
MSMEG_2219|M.smegmatis_MC2_155      TPPFRTMAKPVIVAINGICCGAGLDWVTTGDIVIASDKATFFDPHVSIGL
MAV_1582|M.avium_104                TPPFRTMAKPVLTAVNGICCGAGMDWVTTTDIVIASEQATFFDPHVSIGL
TH_4071|M.thermoresistible__bu      TPPFRTMAKPVLAAINGICCGAGLDWVTTGDIVIASERATFFDPHVSIGL
MMAR_4023|M.marinum_M               TPPFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASEAATFFDPHVSIGL
MUL_3888|M.ulcerans_Agy99           TPLFRSMAKPVLTAVNGICCGAGLDWVTTSDIVIASETATFFDPHVSIGL
Mb1099c|M.bovis_AF2122/97           GKLAAVRT-PTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGV
Rv1070c|M.tuberculosis_H37Rv        GKLAAVRT-PTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGV
MLBr_02402|M.leprae_Br4923          GKLAAVRT-PMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
MAB_0836c|M.abscessus_ATCC_199      LLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGL
                                           : * :.*: * . *.* :     *: :: : *.*  *.:. *:

Mflv_4360|M.gilvum_PYR-GCK          VAAR-EMVRLARALPRSVALRMALMGKHERMTAERAYELGMITEVVPHDT
Mvan_1984|M.vanbaalenii_PYR-1       VAAR-EMVRLARALPRSVALRMALMGKHERMSAERAYELGMITEVVEHDK
MSMEG_2219|M.smegmatis_MC2_155      VAAR-EMVRLARALPRSVALRMALMGKHERMTVERAYELGLITEIVEHDN
MAV_1582|M.avium_104                VAGR-ELVRVSRVLPRSIALRMALMGKHERMSAQRAYELGLISEIVEHDR
TH_4071|M.thermoresistible__bu      VSGR-EVVRLARVLPRSVALRMAIMGRHERMSAQRAYELGMVSEVVEHDR
MMAR_4023|M.marinum_M               VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
MUL_3888|M.ulcerans_Agy99           VAGR-ELVRLARVLPRSVALRMALVGKHERMDARRAFDLGLISEVVEHDR
Mb1099c|M.bovis_AF2122/97           LPGMGGSQRLTRAIGKAKAMDLILTG--RTMDAAEAERSGLVSRVVPADD
Rv1070c|M.tuberculosis_H37Rv        LPGMGGSQRLTRAIGKAKAMDLILTG--RTMDAAEAERSGLVSRVVPADD
MLBr_02402|M.leprae_Br4923          LPGMGGSQRLTRAIGKAKAMDLILTG--RTIDAAEAERSGLVSRVVLADD
MAB_0836c|M.abscessus_ATCC_199      VPGAGSMVRLKRQIPYTKAMEMILTG--EPLTAFEAYHFGLVGHVVPAGT
                                    :..     *: * :  : *: : : *  . : . .*   *:: .:*  . 

Mflv_4360|M.gilvum_PYR-GCK          LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
Mvan_1984|M.vanbaalenii_PYR-1       LLERAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLLEGEILAETFRERVV
MSMEG_2219|M.smegmatis_MC2_155      LLQRAHEIADIVNSNAPLAVRGTRLAIHKTLDLPLHDGEILAETFRERVV
MAV_1582|M.avium_104                LLERAHEIADIVNSNAPLAVRGTRLAILKGLNVPLHEAEILAETFRERVL
TH_4071|M.thermoresistible__bu      LLERAHEIADIVTRNAPLAVRGTRLAIVKGLDLPLHEAEILAEAFRERNL
MMAR_4023|M.marinum_M               LLARAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
MUL_3888|M.ulcerans_Agy99           LLERAHEIADMVNRNAPLAVRGTRLAILKGIDLPLPEAEMLAEAFRERVL
Mb1099c|M.bovis_AF2122/97           LLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAF
Rv1070c|M.tuberculosis_H37Rv        LLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAF
MLBr_02402|M.leprae_Br4923          LLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTF
MAB_0836c|M.abscessus_ATCC_199      ALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVI
                                     * .*:  *  :   .  *.* :: *: :    .  :.      : .  .

Mflv_4360|M.gilvum_PYR-GCK          RTEDAQEGPLAFVEKRAPNWQCR
Mvan_1984|M.vanbaalenii_PYR-1       RTEDAQEGPLAFVEKRAPDWQCR
MSMEG_2219|M.smegmatis_MC2_155      RTEDALEGPLAFVEKRKPVWKCR
MAV_1582|M.avium_104                RTEDAAEGPRAFVEKRQPNWQCR
TH_4071|M.thermoresistible__bu      HTEDSLEGPRAFTEKREPRWQCR
MMAR_4023|M.marinum_M               RTRDALEGPRAFAEKRDPDWQCQ
MUL_3888|M.ulcerans_Agy99           RTRDAFEGPRAFAEKRDPDWQCQ
Mb1099c|M.bovis_AF2122/97           ATEDQSEGMAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv        ATEDQSEGMAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923          VTDDQSEGMAAFIEKRAPQFTHR
MAB_0836c|M.abscessus_ATCC_199      TSADAREGLAAFKEKREARFTGR
                                     : *  **  ** *** . :  :

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_2219	-	-	100% (268)	enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155	MSMEG_2218	-	1e-37	39.06% (233)	enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155	MSMEG_5198	-	5e-34	34.32% (271)	carnitinyl-CoA dehydratase